Find Business Hotels in Otay Mesa, CA

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Our top choices for Otay Mesa business-friendly hotels

Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG

Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG
2.5 star property
Otay Mesa
8.0 out of 10, Very Good, (1569)
"Great place to stay. Really clean and helpful staff "
United States
Zulma
The price is ¥18,609
¥21,168 total
includes taxes & fees
Jan 11 - Jan 12
Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG

Quality Suites San Diego Otay Mesa

Quality Suites San Diego Otay Mesa
2.5 star property
Otay Mesa
7.2 out of 10, Good, (1006)
"Clean, convenient location "
United States
Mary
The price is ¥16,545
¥18,820 total
includes taxes & fees
Jan 11 - Jan 12
Quality Suites San Diego Otay Mesa

Crowne Plaza San Diego - Mission Valley by IHG

Crowne Plaza San Diego - Mission Valley by IHG
3.5 star property
Mission Valley
7.8 out of 10, Good, (1015)
"Room and breakfast "
United States
Juan
The price is ¥14,543
¥16,780 total
includes taxes & fees
Jan 4 - Jan 5
Crowne Plaza San Diego - Mission Valley by IHG

Hyatt Regency Mission Bay Spa and Marina

Hyatt Regency Mission Bay Spa and Marina
4.0 star property
Mission Bay
8.4 out of 10, Very Good, (1589)
"Totally Recommend! Rooms are really clean and comfortable, the staff are great as well. "
United States
Fernando
The price is ¥20,955
¥32,361 total
includes taxes & fees
Jan 10 - Jan 11
Hyatt Regency Mission Bay Spa and Marina

San Diego Mission Bay Resort

San Diego Mission Bay Resort
4.0 star property
Mission Bay
8.4 out of 10, Very Good, (1317)
"Room was super clean and updated, location up against the bay was perfect. We really enjoyed our stay and want to come back soon!"
United States
Haley
The price is ¥21,455
¥32,930 total
includes taxes & fees
Jan 4 - Jan 5
San Diego Mission Bay Resort

Sycuan Casino Resort

Sycuan Casino Resort
4.0 star property
El Cajon
9.2 out of 10, Wonderful, (1651)
"Very nice getaway for the family "
United States
Richard
Sycuan Casino Resort

Hampton Inn & Suites by Hilton San Diego SeaWorld

Hampton Inn & Suites by Hilton San Diego SeaWorld
3.0 star property
Point Loma
9.2 out of 10, Wonderful, (461)
"Clean room, helpful staff, convenient location "
United States
David
The price is ¥18,485
¥21,248 total
includes taxes & fees
Jan 7 - Jan 8
Hampton Inn & Suites by Hilton San Diego SeaWorld

Loews Coronado Bay Resort

Loews Coronado Bay Resort
4.0 star property
Silver Strand
8.8 out of 10, Excellent, (1059)
"Clean room, gorgeous grounds, very friendly staff "
United States
Taryn
The price is ¥31,120
¥42,176 total
includes taxes & fees
Jan 3 - Jan 4
Loews Coronado Bay Resort

Wyndham San Diego Bayside

Wyndham San Diego Bayside
4.0 star property
Downtown San Diego
8.4 out of 10, Very Good, (6014)
"Always an amazing stay"
United States
Jana
The price is ¥19,806
¥28,406 total
includes taxes & fees
Jan 4 - Jan 5
Wyndham San Diego Bayside

DoubleTree by Hilton Hotel San Diego - Mission Valley

DoubleTree by Hilton Hotel San Diego - Mission Valley
4.0 star property
Mission Valley
8.4 out of 10, Very Good, (1445)
"The room was super quiet and clean. The staff was kind at check in and check out. We would definitely stay here again. "
United States
Janelle
The price is ¥18,465
¥21,224 total
includes taxes & fees
Jan 4 - Jan 5
DoubleTree by Hilton Hotel San Diego - Mission Valley
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Otay Mesa Hotel Reviews

Frequently asked questions

Why book your business-friendly hotel in Otay Mesa with Expedia?
Here at Expedia, our business is to help you land an excellent stay at the right price. From upmarket, corporate-friendly retreats to affordable hotels loaded with amenities, you'll have your next work trip organized in a few quick clicks.
How can I find cheap business-friendly hotels in Otay Mesa?
Select the "business friendly" filter, listed under the "traveler experience" heading, to find cheap business-friendly hotels in Otay Mesa. Then refine your search by your nightly budget. Looking for properties outside the city center is another good way to save.

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