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Our top choices for South San Diego hotels

A Holiday Inn Express building with a prominent entrance, palm trees, and a clear sky.

1. Holiday Inn Express San Diego South - Chula Vista by IHG

Chula Vista

Daniel

￥29,717 total

includes taxes & fees

Nov 18 - Nov 19

A hotel room with a large bed, a desk with a chair, a nightstand, a mirror, and a blue-striped carpet.

2. Best Western Chula Vista/Otay Valley Hotel

Otay

Mario

￥19,063 total

includes taxes & fees

Nov 15 - Nov 16

A hotel room with two beds, a television, a desk, and a dresser.

3. La Quinta Inn by Wyndham San Diego Chula Vista

Chula Vista

Nuwan

￥18,439 total

includes taxes & fees

Nov 29 - Nov 30

A conference room with rows of chairs, a large window with curtains, a flat-screen TV on the wall, and a patterned carpet.

4. Hampton Inn & Suites Imperial Beach San Diego

Mar Vista

Joshua

￥25,881 total

includes taxes & fees

Nov 29 - Nov 30

A hotel lobby with a patterned carpet, a reception desk, a sofa with cushions, and potted plants.

5. Comfort Inn Chula Vista San Diego South

Chula Vista

Xochitl

￥18,082 total

includes taxes & fees

Nov 29 - Nov 30

An outdoor patio area with seating and a bar.

6. Ayres Hotel San Diego South - Chula Vista

Otay Ranch

Rosemary

￥30,055 total

includes taxes & fees

Nov 29 - Nov 30

A rooftop terrace with seating, a table with bottles, and a view of the ocean at sunset.

7. Pier South Resort, Autograph Collection by Marriott

Seacoast

David

￥40,741 total

includes taxes & fees

Nov 1 - Nov 2

A modern hotel with a prominent 'Hercor Hotel' sign, multiple balconies, and a 'Urban Boutique' label.

8. Hercor Hotel - Urban Boutique

Chula Vista

fannie

￥19,354 total

includes taxes & fees

Nov 19 - Nov 20

A spacious lobby with a large seating area, a reception desk, and a television screen.

9. Element by Marriott San Diego Chula Vista

Otay Ranch

Maricela

￥40,329 total

includes taxes & fees

Nov 22 - Nov 23

A spacious lobby with a flat-screen TV, a fireplace, and comfortable seating areas.

10. Residence Inn by Marriott San Diego Chula Vista

Otay Ranch

Leslie

￥33,552 total

includes taxes & fees

Nov 8 - Nov 9

A modern interior with a long table and blue chairs, large windows with a view of palm trees and parked vehicles outside.

11. Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG

Otay Mesa

Helen

￥23,869 total

includes taxes & fees

Nov 29 - Nov 30

A spacious lobby with a fireplace, wooden furniture, and a chandelier.

12. Best Western Americana Inn

San Ysidro

Rene

￥18,794 total

includes taxes & fees

Nov 22 - Nov 23

A retro-themed arcade with classic games, a foosball table, and a long communal table with stools.

13. The Rambler Hotel

Chula Vista

Neal

￥21,344 total

includes taxes & fees

Nov 4 - Nov 5

An outdoor seating area with fire pit, lounge chairs, and tables, adjacent to a building with large windows and a brick facade.

14. Hampton Inn Chula Vista Eastlake

Chula Vista

jose

￥28,797 total

includes taxes & fees

Nov 29 - Nov 30

A modern living room with a large window, a fireplace, and a kitchen area.

15. Rodeway Inn San Diego South San Ysidro Border

San Ysidro

Guadalupe

￥15,343 total

includes taxes & fees

Nov 4 - Nov 5

A hotel with a large swimming pool, multiple water slides, and a well-lit outdoor area with lounge chairs and umbrellas.

16. Gaylord Pacific Resort & Convention Center

Chula Vista

Joane

￥57,531 total

includes taxes & fees

Nov 29 - Nov 30

A modern hotel room with a large bed, bedside tables, a desk, and a mirror.

17. Motel 6 San Diego, CA - Southbay

Nestor

Sandra

￥13,417 total

includes taxes & fees

Nov 15 - Nov 16

A modern kitchen with a herringbone-patterned backsplash, a central island with a coffee machine, and pendant lighting.

18. Quality Inn San Diego South - Chula Vista

Chula Vista

Yolanda

￥15,931 total

includes taxes & fees

Nov 22 - Nov 23

A compact kitchen with a sink, a microwave, a coffee maker, and a TV mounted above the counter.

19. Studio 6 Suites San Ysidro, CA -San Diego South Bay

San Ysidro

Zach

￥14,730 total

includes taxes & fees

Nov 22 - Nov 23

A neatly arranged hotel room with a large bed, a desk, a chair, and a bedside table.

20. Valli Hi Motel

San Ysidro

Christian

￥14,562 total

includes taxes & fees

Nov 1 - Nov 2

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Stay near popular South San Diego attractions

The exterior of the Mattress Firm Amphitheatre with palm trees and a clear sky.

North Island Credit Union Amphitheatre

7.6/10 (374 reviews)

You can enjoy a show at North Island Credit Union Amphitheatre on your trip to Chula Vista. Experience the acclaimed theater scene and great live music in this walkable area.

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Learn more about South San Diego

Discover the family-friendly area of South San Diego—theaters, natural beauty, and sights from Sesame Place San Diego to North Island Credit Union Amphitheatre.

See all hotels in South San Diego

A silhouette of a person holding a surfboard against a sunset.

Top South San Diego Hotel Reviews

The Alcala Hotel Mission Valley/Seaworld

10/10 Excellent

"The staff was amazing. Very attentive to our needs during our stay. The pool was clean and heated the jacuzzi was great, room was nice and clean and the breakfast was a plus. The only down fall was in the rooms it gets so muggy and humid. Also parking is 10 a night but is secure. Over all a great stay!"

Bay Club Hotel & Marina

10/10 Excellent

"The room was very clean, bed & pillows were so comfortable. The front desk staff was helpful & I was quickly supplied with extra coffee & cups for my room. The view from balcony was magnificent. Onsite restaurant had fantastic breakfast. This was my second time staying here & next time I’m in San Diego I will definitely be booking a stay here again"

Wyndham San Diego Bayside

10/10 Excellent

"Nice clean room, central located to walking activities. It's nice to have a view of the bay but not nice to look onto the dirty roof tops of the buildings in front of us. That I do not know if they can do anything about. On a nicer note we spoke with a lovely lady about different eating places we could walk to, she even gave up a coupon to eat at a few that were in front of the hotel, down the water front."