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Find hotels in South San Diego, CA from ￥10,320

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November 2026

December 2026

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Our top choices for South San Diego hotels

A buffet with various food items, including omelets and other dishes, served in metal trays.

1. Holiday Inn Express San Diego South - Chula Vista by IHG

Chula Vista

Daniel

￥27,020 total

includes taxes & fees

Dec 6 - Dec 7

A modern kitchen area with a self-serve station, including a waffle maker, coffee machine, and various food items.

2. Best Western Chula Vista/Otay Valley Hotel

Otay

Edna

￥19,149 total

includes taxes & fees

Nov 15 - Nov 16

A breakfast bar with La Quinta branding, a coffee machine, and a waffle display.

3. La Quinta Inn by Wyndham San Diego Chula Vista

Chula Vista

Luis

￥17,930 total

includes taxes & fees

Nov 29 - Nov 30

A spacious lobby with a modern design, featuring a large seating area, a reception desk, and large windows offering views of the city.

4. Ayres Hotel San Diego South - Chula Vista

Otay Ranch

Rosemary

￥29,520 total

includes taxes & fees

Nov 29 - Nov 30

An outdoor patio with a fire feature, seating, and large windows.

5. Hampton Inn & Suites Imperial Beach San Diego

Mar Vista

Joshua

￥26,966 total

includes taxes & fees

Nov 8 - Nov 9

A hotel lobby with a patterned carpet, a reception desk, a sofa with cushions, and potted plants.

6. Comfort Inn Chula Vista San Diego South

Chula Vista

Xochitl

￥18,110 total

includes taxes & fees

Nov 29 - Nov 30

A modern hotel with a prominent 'Hercor Hotel' sign, multiple balconies, and a 'Urban Boutique' label.

7. Hercor Hotel - Urban Boutique

Chula Vista

fannie

￥19,321 total

includes taxes & fees

Nov 19 - Nov 20

A spacious lobby with a large seating area, a reception desk, and a television screen.

8. Element by Marriott San Diego Chula Vista

Otay Ranch

Maricela

￥32,509 total

includes taxes & fees

Nov 15 - Nov 16

A retro-themed arcade with classic games, a foosball table, and a long communal table with stools.

9. The Rambler Hotel

Chula Vista

Neal

￥16,139 total

includes taxes & fees

Dec 1 - Dec 2

A rooftop terrace with seating, a table with bottles, and a view of the ocean at sunset.

10. Pier South Resort, Autograph Collection by Marriott

Seacoast

Timothy

￥40,668 total

includes taxes & fees

Nov 15 - Nov 16

A modern interior with a long table and blue chairs, large windows with a view of palm trees and parked vehicles outside.

11. Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG

Otay Mesa

Renato

￥23,435 total

includes taxes & fees

Dec 6 - Dec 7

A spacious lobby with a fireplace, wooden furniture, and a chandelier.

12. Best Western Americana Inn

San Ysidro

Erika

￥18,877 total

includes taxes & fees

Nov 22 - Nov 23

A compact kitchen with a sink, a microwave, a coffee maker, and a TV mounted above the counter.

13. Studio 6 Suites San Ysidro, CA -San Diego South Bay

San Ysidro

Zach

￥11,757 total

includes taxes & fees

Nov 9 - Nov 10

A hotel with a large swimming pool, multiple water slides, and a well-lit outdoor area with lounge chairs and umbrellas.

14. Gaylord Pacific Resort & Convention Center

Chula Vista

Joane

￥57,429 total

includes taxes & fees

Nov 29 - Nov 30

A modern hotel room with a shower, a bed, a desk, and a window with a view.

15. Hampton Inn Chula Vista Eastlake

Chula Vista

jose

￥28,498 total

includes taxes & fees

Nov 15 - Nov 16

A modern living room with a large window, a fireplace, and a kitchen area.

16. Rodeway Inn San Diego South San Ysidro Border

San Ysidro

Guadalupe

￥13,543 total

includes taxes & fees

Nov 15 - Nov 16

A room with two teal armchairs, a small round table with a lamp, and a large cityscape painting on the wall.

17. SureStay Hotel by Best Western Chula Vista San Diego Bay

Chula Vista

Sergio

￥13,278 total

includes taxes & fees

Nov 19 - Nov 20

A spacious lobby with a flat-screen TV, a fireplace, and comfortable seating areas.

18. Residence Inn by Marriott San Diego Chula Vista

Otay Ranch

Leslie

￥32,683 total

includes taxes & fees

Nov 30 - Dec 1

A modern kitchen with a herringbone-patterned backsplash, a central island with a coffee machine, and pendant lighting.

19. Quality Inn San Diego South - Chula Vista

Chula Vista

Yolanda

￥15,122 total

includes taxes & fees

Nov 29 - Nov 30

A modern hotel room with a large bed, bedside tables, a desk, and a mirror.

20. Motel 6 San Diego, CA - Southbay

Nestor

Sandra

￥13,391 total

includes taxes & fees

Nov 24 - Nov 25

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Stay near popular South San Diego attractions

The exterior of the Mattress Firm Amphitheatre with palm trees and a clear sky.

North Island Credit Union Amphitheatre

7.6/10 (374 reviews)

You can enjoy a show at North Island Credit Union Amphitheatre on your trip to Chula Vista. Experience the acclaimed theater scene and great live music in this walkable area.

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Learn more about South San Diego

Discover the family-friendly area of South San Diego—theaters, natural beauty, and sights from Sesame Place San Diego to North Island Credit Union Amphitheatre.

See all hotels in South San Diego

Top South San Diego Hotel Reviews

Ayres Hotel San Diego South - Chula Vista

Otay Ranch

10/10 Excellent

Excellent customer service. Very clean throughout the hotel and inside room and bathroom. Room and bathroom is spacious. Tub shower is excellent. Water pressure is super. The family loved the Pool and hot tub area. Also outdoor area is available and there’s an outdoor bar that opens in the evening. Breakfast in the morning was delicious with waffles, pancakes, eggs, a protein and potatoes. Can also request for kitchen staff to make an omelet if you prefer. Will definitely recommend this hotel.

Madeline