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Go beyond your typical stay in South Carolina Midlands

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Our top choices for South Carolina Midlands hotels

TRU BY Hilton North Augusta

North Augusta

April

￥19,719 total

includes taxes & fees

Jun 21 - Jun 22

Aiken Midtown Hotel

Aiken

Evelio

￥14,871 total

includes taxes & fees

Jul 16 - Jul 17

La Quinta Inn by Wyndham Columbia SE / Fort Jackson

Columbia

Marvin

￥14,701 total

includes taxes & fees

Jul 12 - Jul 13

Holiday Inn Express & Suites Latta by IHG

Latta

Diana

￥19,911 total

includes taxes & fees

Jun 21 - Jun 22

Howard Johnson by Wyndham Florence

Florence

michael

￥12,114 total

includes taxes & fees

Jun 16 - Jun 17

Room, 2 Queen Beds, Non Smoking | Desk, blackout drapes, iron/ironing board, free WiFi

Baymont by Wyndham Santee

Santee

Gary

￥13,337 total

includes taxes & fees

Jun 16 - Jun 17

Suite, 1 King Bed with Sofa bed, Non Smoking | Premium bedding, desk, iron/ironing board, free cribs/infant beds

Quality Inn & Suites Florence Civic Center

Florence

Kim

￥15,828 total

includes taxes & fees

Jun 17 - Jun 18

Best Western Plus Santee Inn

Santee

Nicole

￥19,210 total

includes taxes & fees

Jun 18 - Jun 19

Springhill Suites by Marriott Columbia near Fort Jackson

Columbia

Mary

￥17,768 total

includes taxes & fees

Jul 12 - Jul 13

Best Western Rock Hill

Rock Hill

Charmaine

￥12,664 total

includes taxes & fees

Jun 21 - Jun 22

Tru By Hilton Santee

Santee

Jeffrey

￥18,853 total

includes taxes & fees

Jun 21 - Jun 22

LivSmart Studios by Hilton Columbia Greystone

Columbia

￥19,253 total

includes taxes & fees

Jul 12 - Jul 13

Hilton Garden Inn Columbia/Harbison

Columbia

Stephone

￥16,777 total

includes taxes & fees

Jun 28 - Jun 29

Holiday Inn Express Richburg by IHG

Richburg

Linda

￥18,843 total

includes taxes & fees

Jun 28 - Jun 29

Carriage House Inn

Aiken

Melissa

￥21,429 total

includes taxes & fees

Jun 17 - Jun 18

Imperial motel

Mullins

James

￥10,962 total

includes taxes & fees

Jun 16 - Jun 17

Park Inn by Radisson Florence, SC

Florence

Pierre

￥16,878 total

includes taxes & fees

Jun 21 - Jun 22

Fairfield Inn & Suites by Marriott Santee

Santee

Carl

￥23,851 total

includes taxes & fees

Jun 21 - Jun 22

La Quinta Inn & Suites by Wyndham Florence

Florence

Ray

￥15,103 total

includes taxes & fees

Jun 16 - Jun 17

Comfort Inn & Suites Florence Center Area

Florence

Dana

￥19,583 total

includes taxes & fees

Jun 28 - Jun 29

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Vacation Rentals in South Carolina Midlands

Cottage

Lake Access & Boat Slip: Greenwood Cottage!

Greenwood

"Outstanding little cottage for my mom and daughter weekend! Super clean and comfortable. "

Vacation Home

Signature Townhome, 3 Bedrooms, Balcony, River View | Water view

Beautiful 3BR Townhouse

East Augusta

"The water view and close proximity to restaurants and shops The place was as pictured and some. Very quiet and relaxing place. Will definitely be booking again"

Aparthotel

stayAPT Suites Rock Hill

Rock Hill

"Would never book here again.. drove 12 hours and when we got into the place it hardly looked cleaned. No one ever came to restock the toiletries or towels etc. Extra sheets that were given for the pull out couch literally had cigarette burn holes in them and there was a sheet left on the pull out couch with fecal stains on it. Upon leaving yesterday we also saw cockroaches. Never again. outrageous price for 3 nights not worth it. Not to mention every time we needed to talk to the front desk no...

Apartment

Easy Access to I-77 & I-20: Columbia Duplex!

Columbia

"It was very nice and pleasant. Quiet neighborhood."

Cottage

3 Mi to Marina: Quiet Getaway w/ Deck in Lexington

Lexington

"Very cozy home lots of room and kept clean!"

Cottage

1 Mi to Lake Murray! Pet-friendly Extended Base

Hollands Landing

Cottage

Peaceful Camden Vacation Rental ~ 3 Mi to Town!

Camden

"Location was perfect for us. Very cozy, and clean. Hadn't been modernized, but it was in great shape. Nasolgic; felt like I was visiting my grandparents! Only having one bathroom was a bit challenging, but we made it work!"

Cottage

Stunning Lakefront Retreat w/ Dock Access!

Greenwood

Cottage

Bright Hopkins Home w/ Game Room & Fire Pit!

Hopkins

Cottage

Prosperity Vacation Rental ~ 1 Mi to Lake Murray!

Hollands Landing

"The property had a lot of land. It was a peaceful, beautiful scenery. They had games in the house, ax throwing, corn hole outside & bonfire. Seeing the neighbors horses walk by was amazing. "

Cottage

Spacious Aiken Home ~ 8 Mi to Downtown!

Aiken

"We loved how spacious the house was! Lots of comfortable seating options. Beds were comfortable! "

Cottage

Greenwood Getaway w/ Furnished Patio & Lake View

Greenwood

"Wonderful stay and would definitely stay again! Reasonable price for the luxury place with everything that you could ask for in a rental. Close to restaurants and bars if that is your thing and right near the lake with beautiful views!! We loved our stay!"

Cottage

Columbia Vacation Rental < 2 Mi to University

Downtown Columbia

"House was very welcoming, with a cottage vibe, the older home renovations mixed with the floor and trim work over the doors was beautiful and unique. Very updated home nicely done. "

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Stay near popular South Carolina Midlands attractions

Carowinds Theme Park

4.4/5 (962 reviews)

Choose from 13 roller coasters, chase your friends in a bumper car, enjoy the water slides and beaches of Boomerang Bay, and walk with dinosaurs.

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Learn more about South Carolina Midlands

With Revolutionary War sites, a charming capital city and lots of kayaking opportunities, this southern region is sure to delight.

See all hotels in South Carolina Midlands

Top South Carolina Midlands Hotel Reviews

Moxy Columbia Downtown

10/10 Excellent

"The rooftop bar and location are impeccable. This is my second stay. I love it both times"

Hyatt Place Columbia/Downtown/The Vista

4/10 Poor

"Overall, hotel was clean and updated, and the staff was friendly (with one exception). There is a mandatory $20 parking fee - not an issue, but the parking situation is awful. We paid the fee, but there was no attendant to give us the card for the garage. The person at the desk told us not to worry about it, just give them our room number and they’d mark us down for when we came back later that day after checking in. When we got back, there were no available parking spaces and we couldn’t get into the overflow garage because we didn’t have the ticket from the valet/parking attendant being absent earlier in the day. I waited in the car behind a couple other of vehicles for valet to come and get us situated. After several minutes with no movement, I went inside to the front desk and told them about the situation. They said valet had stepped out and they didn’t know when they’d be back. I explained that I was stuck with my three toddlers in the car and could t park because they hadn’t given me a ticket when I paid earlier. At this point there was a line of 7-8 cars behind me with no one able to park or get into their room because of the situation. The one staff member at the front desk was clearly overwhelmed and unable to help us. Valet finally showed up and we were able to get parked around 45 minutes after getting there, which is an eternity with young kids in tow. Overall, the hotel was great, but the parking situation truly spoiled the stay."