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Our top choices for Santa María hotels

ibis Cartagena Marbella

ibis Cartagena Marbella
3.0 star property
Marbella
8.2 out of 10, Very Good, (1007)
"Excellent hotel "
Canada
Nizar
The price is ¥9,149
¥9,149 total
Dec 19 - Dec 20
ibis Cartagena Marbella

Hotel Ayenda Casa Cano 1805

Hotel Ayenda Casa Cano 1805
3.0 star property
Marbella
8.2 out of 10, Very Good, (209)
"Great location, beautiful "
United States
Joseph
The price is ¥8,359
¥8,359 total
Jan 13 - Jan 14, 2026
Hotel Ayenda Casa Cano 1805

Sonesta Hotel Cartagena

Sonesta Hotel Cartagena
4.0 star property
La Boquilla
8.0 out of 10, Very Good, (1002)
"Everything looked amazing"
United States
Yely
The price is ¥21,361
¥21,361 total
Dec 17 - Dec 18
Sonesta Hotel Cartagena

Varanasi Hotel Boutique

Varanasi Hotel Boutique
3.0 star property
Marbella
9.2 out of 10, Wonderful, (578)
"room clean all good"
United States
Steven
The price is ¥17,447
¥17,447 total
Dec 25 - Dec 26
Varanasi Hotel Boutique

Hotel Capilla del Mar

Hotel Capilla del Mar
4.0 star property
Bocagrande
8.8 out of 10, Excellent, (1002)
"nice location and friendly staff. However, construction across the street is an eye sore."
United States
Narayan
The price is ¥18,454
¥18,454 total
Dec 22 - Dec 23
Hotel Capilla del Mar

GHL San Lazaro Art Hotel

GHL San Lazaro Art Hotel
4.0 star property
Pie del Cerro
9.2 out of 10, Wonderful, (914)
"I really have a great time, perfect place to get to know the City right in the middle of everything Hotel was clean, big room, staff members "
United States
Jose E
The price is ¥16,942
¥16,942 total
Jan 16 - Jan 17, 2026
GHL San Lazaro Art Hotel

Movich Hotel Cartagena de Indias

Movich Hotel Cartagena de Indias
4.0 star property
Cartagena Walled City
9.4 out of 10, Exceptional, (554)
"The room was clean and well appointed but just a little bit musty when we entered. I loved the location of this hotel it was near to everything no need for cabs. The staff were very helpful and friendly. The food was just meh, the menu could be more varied especially breakfast. We loved the rooftop restaurant for the view and atmosphere. I would stay there again but just eat out more. "
United States
Desalyn Teresa
The price is ¥64,299
¥64,299 total
Dec 17 - Dec 18
Movich Hotel Cartagena de Indias

GHL Corales de Indias

GHL Corales de Indias
4.0 star property
Marbella
8.0 out of 10, Very Good, (1001)
"Habitacion"
Mexico
Mario
The price is ¥22,498
¥22,498 total
Jan 13 - Jan 14, 2026
GHL Corales de Indias

GHL Arsenal Hotel

GHL Arsenal Hotel
4.0 star property
Cartagena Walled City
9.2 out of 10, Wonderful, (1003)
"Everything went perfect! The staff and rooms were amazing! We will definitely stay there again! "
United States
Zoraida
The price is ¥27,436
¥27,436 total
Jan 14 - Jan 15, 2026
GHL Arsenal Hotel

Hotel Summer Frente Al Mar

Hotel Summer Frente Al Mar
3.0 star property
La Boquilla
8.0 out of 10, Very Good, (527)
"The experience was amazing! The attention was excellent. The food was delicious. Just a heads up, the hotel is near the airport, so there will be some noise. "
United States
Merly
Hotel Summer Frente Al Mar

Hotel Don Pedro de Heredia

Hotel Don Pedro de Heredia
3.5 star property
Cartagena Walled City
8.4 out of 10, Very Good, (725)
"Excellent location, clean room, very comfortable, nice staff."
United States
Alexander
The price is ¥10,623
¥10,623 total
Dec 18 - Dec 19
Hotel Don Pedro de Heredia

Bondo Estudio

Bondo Estudio
3.5 star property
Marbella
9.2 out of 10, Wonderful, (615)
"Great location and very friendly and professional staff. "
United States
Jeffrey
The price is ¥12,902
¥12,902 total
Dec 18 - Dec 19
Bondo Estudio

Hotel Oceania Cartagena

Hotel Oceania Cartagena
3.0 star property
El Laguito
7.4 out of 10, Good, (55)
"Very affordable accommodation in a higly touristic area. The facilities are basic, but decent."
United States
Lex
The price is ¥7,086
¥8,315 total
Dec 18 - Dec 19
Hotel Oceania Cartagena

Casa Claver Loft Boutique Hotel

Casa Claver Loft Boutique Hotel
4.0 star property
Cartagena Walled City
9.6 out of 10, Exceptional, (579)
"Hotel is great, customer service, cleanliness, close to everything. Amazing stay! "
United States
Esperanza
The price is ¥41,825
¥41,825 total
Dec 21 - Dec 22
Casa Claver Loft Boutique Hotel

Osh Hotel Cartagena

Osh Hotel Cartagena
3.5 star property
Cartagena Walled City
9.6 out of 10, Exceptional, (749)
"Great hotel and staff!"
United States
Todd
The price is ¥32,730
¥32,730 total
Dec 17 - Dec 18
Osh Hotel Cartagena

Ganem Suites Cartagena

Ganem Suites Cartagena
3.0 star property
Cartagena Walled City
8.8 out of 10, Excellent, (148)
"A really good place to stay in the Walled city got people staying over a weeek."
United States
Sierria
The price is ¥10,475
¥11,909 total
Dec 17 - Dec 18
Ganem Suites Cartagena

Hotel Regatta Cartagena

Hotel Regatta Cartagena
3.5 star property
Bocagrande
7.8 out of 10, Good, (702)
"Great location "
United States
Hector
The price is ¥18,543
¥18,543 total
Dec 18 - Dec 19
Hotel Regatta Cartagena

Bastión Luxury Hotel

Bastión Luxury Hotel
4.5 star property
Cartagena Walled City
9.6 out of 10, Exceptional, (1003)
"Beautiful property "
Canada
Linda
The price is ¥42,027
¥42,027 total
Dec 17 - Dec 18
Bastión Luxury Hotel

Townhouse Boutique Hotel

Townhouse Boutique Hotel
4.0 star property
Cartagena Walled City
9.2 out of 10, Wonderful, (384)
"Excellent staff, clean room, and beautiful roof -top restaurant/ bar."
Canada
Silvia
The price is ¥23,370
¥23,370 total
Dec 17 - Dec 18
Townhouse Boutique Hotel

Sofitel Barú Cartagena

Sofitel Barú Cartagena
5.0 star property
Cartagena
9.4 out of 10, Exceptional, (620)
"Great stay"
United States
Neil
The price is ¥56,092
¥56,092 total
Dec 22 - Dec 23
Sofitel Barú Cartagena
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santa María Hotel Reviews

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Frequently asked questions

Where is the best place to stay in Santa María?
Located 4.3 mi (6.9 km) from the heart of Santa María, Hilton Cartagena is a top choice for your stay based on our traveler data. Two other choices for your stay in the area are Hyatt Regency Cartagena and ibis Cartagena Marbella. See all available top hotels, or vacation rentals in Santa María.
What's the top vacation rental that Santa María has to offer?
Casa Baloco: This vacation home rental near Santa María is located in the city center and has a terrace, a garden, and air-conditioning to put you at ease in your new surroundings. Kitchen amenities include kitchenware to make your meal-planning easier. You and your friends and family can relax into your vacation with amenities like a hot tub. See all vacation rentals in Santa María.
If I need to cancel my hotel reservation in Santa María, will I receive a refund?
Yes, you'll find most hotel reservations are fully refundable if cancelled prior to the hotel's cancellation deadline, which often is within 24-48 hours of your check-in date. If you booked a non-refundable reservation, you may still be able to cancel and get a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Santa María.
Where can I learn more about changing or cancelling my trip to Santa María?
To access more information about rescheduling or cancelling your trip to Santa María, head over to our customer service page.
What are some hotels with pools in Santa María?
Hilton Cartagena: Resort, 9-minute walk from Bocagrande Beach. Features 4 outdoor pools, a children's pool, and a full-service spa. Hyatt Regency Cartagena and Hotel Almirante Cartagena - Colombia are a couple of other choices that offer an onsite pool. View all hotels with pools in Santa María.
How is it staying in Santa María?
Visitors are sure to enjoy all that Santa María has to offer. In Santa María, there are 10 hotels and other accommodations to choose from. Find out more about Santa María.
What are the top places to visit in Santa María?
Places to visit in the wider area include Marbella Beach, Las Americas International Convention Center, and La Boquilla Beach. You'll also find Walls of Cartagena and Centro Comercial La Serrezuela in the area. Check out what more to see and do in Expedia's Santa María guide.
What's the weather like in Santa María?
The hottest months are usually February and March with an average temp of 82°F, while the coldest months are January and February with an average of 82°F. The rainiest months in Santa María are October, November, August, and September, with each month seeing an average of 11 inches of rainfall.

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