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Find hotels in San Francisco, Panama City from ￥7,179

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Discover 1,542 San Francisco hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Our top choices for San Francisco hotels

Las Americas Golden Tower Panama
View from property

Las Americas Golden Tower Panama

4.0 star property
9.0 out of 10, Wonderful, (1023)
"Very friendly staff, room was also very clean"
The price is ￥21,319
￥23,450 total
includes taxes & fees
Sep 28 - Sep 29
Las Americas Golden Tower Panama
Residence Inn by Marriott Panama City
Outdoor pool, open 6:00 AM to 11:00 PM, pool umbrellas, sun loungers

Residence Inn by Marriott Panama City

4.0 star property
9.0 out of 10, Wonderful, (515)
"Stayed here while a relative was hospitalized, easy access to the hospital and shopping center with lots of food options. If visiting Panama city it is very conveniently located."
The price is ￥19,949
￥21,944 total
includes taxes & fees
Oct 25 - Oct 26
Residence Inn by Marriott Panama City
San Francisco by Wynwood House
Lobby sitting area

San Francisco by Wynwood House

3.0 star property
9.2 out of 10, Wonderful, (50)
"Good comfy rooms"
The price is ￥14,218
￥19,702 total
includes taxes & fees
Sep 30 - Oct 1
San Francisco by Wynwood House
Courtyard by Marriott Panama Multiplaza Mall
Reception

Courtyard by Marriott Panama Multiplaza Mall

4.0 star property
8.8 out of 10, Excellent, (1000)
"The breakfast buffet was excellent and the staff was friendly "
The price is ￥19,130
￥21,043 total
includes taxes & fees
Oct 25 - Oct 26
Courtyard by Marriott Panama Multiplaza Mall
Decapolis Hotel Panama City
Exterior

Decapolis Hotel Panama City

4.0 star property
8.6 out of 10, Excellent, (1335)
"The rooms are clean and the staff is very friendly and helpful. The amenities like the hot tub are very good. "
The price is ￥12,530
￥13,783 total
includes taxes & fees
Oct 3 - Oct 4
Decapolis Hotel Panama City
Plaza Paitilla Inn Hotel
View from property

Plaza Paitilla Inn Hotel

3.5 star property
9.4 out of 10, Exceptional, (2125)
"Stayed 4 nights excellent property and views from the room"
The price is ￥22,290
￥24,519 total
includes taxes & fees
Oct 7 - Oct 8
Plaza Paitilla Inn Hotel
JW Marriott Panama
4 outdoor pools, free cabanas, pool umbrellas

JW Marriott Panama

5.0 star property
8.8 out of 10, Excellent, (1013)
"The staff is top notch, the accommodations amazing, the dining options great, close to airport and activities "
The price is ￥33,774
￥37,151 total
includes taxes & fees
Oct 3 - Oct 4
JW Marriott Panama
Sheraton Grand Panama
Terrace/patio

Sheraton Grand Panama

4.0 star property
8.6 out of 10, Excellent, (951)
"Great staff and beautiful hotel. Will definitely stay again!"
The price is ￥19,795
￥21,775 total
includes taxes & fees
Oct 12 - Oct 13
Sheraton Grand Panama
Megapolis Hotel Panamá
Front of property

Megapolis Hotel Panamá

4.5 star property
8.4 out of 10, Very Good, (1093)
"Great place "
The price is ￥18,459
￥20,305 total
includes taxes & fees
Sep 28 - Sep 29
Megapolis Hotel Panamá
Aloft Panama
Exterior

Aloft Panama

3.5 star property
8.6 out of 10, Excellent, (854)
"The buffet breakfast was excellent and staff was very friendly. "
The price is ￥17,282
￥19,010 total
includes taxes & fees
Sep 30 - Oct 1
Aloft Panama
Boutique Apartments Panamá Coco del Mar
Outdoor pool

Boutique Apartments Panamá Coco del Mar

3.5 star property
7.6 out of 10, Good, (131)
"Great view with access to the pool and gym."
The price is ￥4,338
￥24,757 total
includes taxes & fees
Sep 29 - Sep 30
Boutique Apartments Panamá Coco del Mar
Wanders Panama by Boutique Apartments
Outdoor pool

Wanders Panama by Boutique Apartments

4.0 star property
10.0 out of 10, Exceptional, (1)
"I will go again thank you so much"
The price is ￥15,065
￥32,646 total
includes taxes & fees
Sep 28 - Sep 29
Wanders Panama by Boutique Apartments
Boutique Apartments Atlapa
Outdoor pool

Boutique Apartments Atlapa

3.0 star property
7.2 out of 10, Good, (20)
"The area was great, just a short walk to many great places to eat and the supermarket. We enjoyed the facilities and the staff was always friendly and easy to deal with/talk to. Fantastic place to stay."
Boutique Apartments Atlapa
Casa Orquídea
Terrace/patio

Casa Orquídea

2.0 star property
9.0 out of 10, Wonderful, (2)
"For me was very convenient "
The price is ￥9,497
￥10,447 total
includes taxes & fees
Sep 25 - Sep 26
Casa Orquídea
w Bright 1BR w Private Balcony in San Francisco
Apartment | Internet

w Bright 1BR w Private Balcony in San Francisco

2.0 star property
The price is ￥14,502
￥20,339 total
includes taxes & fees
Sep 28 - Sep 29
w Bright 1BR w Private Balcony in San Francisco
w Premium 1BR w Balcony in San Francisco
Apartment | 1 bedroom, Internet

w Premium 1BR w Balcony in San Francisco

2.0 star property
The price is ￥14,856
￥20,729 total
includes taxes & fees
Sep 28 - Sep 29
w Premium 1BR w Balcony in San Francisco
Hyatt Regency Panama City
Restaurant

Hyatt Regency Panama City

4.5 star property
10.0 out of 10, Exceptional, (73)
"Place is very nice, convenient and staff very friendly. "
The price is ￥24,697
￥27,167 total
includes taxes & fees
Sep 27 - Sep 28
Hyatt Regency Panama City
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
Suite, 1 Bedroom, Non Smoking, Golf View (Terrace) | Premium bedding, minibar, in-room safe, desk

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

5.0 star property
9.6 out of 10, Exceptional, (608)
"Staff was lovely - especially front desk, door staff, cleaning team and room service. Only critique is that service was very slow in the restaurant both times but otherwise a lovely visit. "
The price is ￥30,765
￥33,841 total
includes taxes & fees
Oct 5 - Oct 6
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
Gran Evenia Panama
Outdoor pool, sun loungers

Gran Evenia Panama

4.5 star property
9.2 out of 10, Wonderful, (182)
"Excellent hotel and staff."
Gran Evenia Panama
Panama House Bed & Breakfast
Terrace/patio

Panama House Bed & Breakfast

2.5 star property
9.0 out of 10, Wonderful, (172)
"Was amazing the host and the people there was super friendly and welcoming. Also has amazing local food spots within walking distance."
The price is ￥5,085
￥5,593 total
includes taxes & fees
Sep 30 - Oct 1
Panama House Bed & Breakfast
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in San Francisco

Find the best San Francisco areas and neighborhoods for the activities you enjoy most.

Casco Viejo

Unique features of Casco Viejo include the historic sites and bars. Make a stop by Interoceanic Canal Museum or National Theater while you're exploring the area.

Bella Vista

Bella Vista is highly notable for its popular shops, and you might want to visit top sights like Via Espana and Iglesia del Carmen. See more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina.

El Cangrejo

The abundant dining options and casinos are top of the list for many visitors to El Cangrejo. A stop by Crown Casino or Luxor Towers might round out your trip.

Punta Paitilla

Travelers come to Punta Paitilla for its abundant dining options, and you can see top attractions like Avenida Balboa and Multicentro Panama while you're in town.

Calidonia

You might enjoy the shopping while in Calidonia. Cinta Costera is a notable sight, and you can get around town at Estación Lotería or Santo Tomas Station to see more of the city.

Top San Francisco Hotel Reviews

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

10/10 Excellent
"The Riu Plaza was great for the accomadatioms. We had a little mix up with booking in the beginning but they were really professional about it and got it handled. The Pool area was clean and nice to hang out at. The breakfast included was GREAT. The 3 restaurants were great also and the food from Ibiza outside dining for dinner was excellent. The staff were very friendly and helpful. The location of Rui was perfect and very Uber friendly. The view from the Hotel of on the right floor was excellent as well . I would recommend this spot to anyone coming to visit Panamá City. "
Antoine 4-night trip
Posted 2 days ago
Hotel Riu Plaza Panama

Explore a world of travel with Expedia

Explore a world of travel with Expedia

Frequently asked questions

What is San Francisco like?

San Francisco is a welcoming neighborhood that travelers like for its restaurants. Be sure to check out Multiplaza Pacific Mall and Calle 50 as part of your San Francisco travel plans.

Where is the best hotel for a stay in San Francisco?

Based on Expedia customer reviews, Ramada Plaza By Wyndham Panama Punta Pacífica is the highest ranked property in San Francisco. This hotel is a short 4-minute walk from Multiplaza Pacific Mall, and it offers free breakfast and a restaurant. Other top choices in the neighborhood include Residence Inn by Marriott Panama City and Decapolis Hotel Panama City.

How many hotels will I find in San Francisco?

If you're searching for places to stay in Panama City, Expedia has something to meet your needs with 215 San Francisco hotels and other accommodations to choose from.

If I need to cancel my hotel reservation in San Francisco, will I receive a refund?

Yes! Most room reservations are fully refundable if you cancel prior to the hotel's cancellation deadline, which often is within 24-48 hours of the scheduled arrival. If you have a non-refundable reservation, you might be able to cancel it and receive a refund within a 24-hour period of booking. Add dates, click "Search", then use the "fully refundable" filter to get top deals in San Francisco.

Where can I learn more about changing or cancelling my trip to San Francisco?

For additional details about updating your trip to San Francisco or cancelling it, head over to our customer service page.

What is there to do in this Panama City neighborhood?

While you're in San Francisco, a shopping trip to Multiplaza Pacific Mall, Avenida Balboa, or Pacific Center, might be the perfect place to find that souvenir you've been looking for. Calle 50 and Panama Canal Murals are some other stops to visit in the neighborhood. A few places to visit in the area around San Francisco include Colonial Religious Art Museum, Bingo 90, and Soho City Center. When you're sightseeing in Panama City, National Shrine of the Heart of Mary and Panama Viejo Museum are also worth a stop.