
Find hotels in Serra Mesa, San Diego
- Change your mindBook hotels with free cancellation
- Be pickySearch almost a million properties worldwide
Check prices for these dates
Our top choices for Serra Mesa hotels

Heritage Inn San Diego
Heritage Inn San Diego
Urban Boutique Hotel
Urban Boutique Hotel
SureStay Hotel by Best Western San Diego Pacific Beach
SureStay Hotel by Best Western San Diego Pacific Beach
GreenTree Inn San Diego Mission Bay
GreenTree Inn San Diego Mission Bay
Gaslamp Plaza Suites
Gaslamp Plaza Suites
Comfort Inn Sea World Area
Comfort Inn Sea World Area
La Quinta Inn & Suites by Wyndham San Diego Mission Bay
La Quinta Inn & Suites by Wyndham San Diego Mission Bay
Comfort Inn San Diego Airport At The Harbor
Comfort Inn San Diego Airport At The Harbor
Ocean Villa Inn
Ocean Villa Inn
Best Western Yacht Harbor Hotel
Best Western Yacht Harbor Hotel
Wyndham Garden San Diego Near SeaWorld
Wyndham Garden San Diego Near SeaWorld
The Shoal La Jolla Beach
The Shoal La Jolla Beach
PB Surf Beachside Inn
PB Surf Beachside Inn
The Horton Grand, Downtown/Gaslamp Quarter
The Horton Grand, Downtown/Gaslamp Quarter
Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter
Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter
Pacific Shores Inn on Pacific Beach
Pacific Shores Inn on Pacific Beach
Embassy Suites by Hilton San Diego Bay Downtown
Embassy Suites by Hilton San Diego Bay Downtown
Beach Haven - Near Pacific Beach Park
Beach Haven - Near Pacific Beach ParkWhere to stay in Serra Mesa

Downtown San Diego
Cultural and financial hub, Downtown San Diego boasts the Symphony, Opera, theaters, museums, and historic sites like Gaslamp Quarter. Enjoy diverse shops, dining, nightlife, and convenient public transport options.

Pacific Beach
Boasting a lively nightlife scene, Pacific Beach offers miles of sandy shores, a bustling 3.2-mile boardwalk, and attractions like Crystal Pier and Kate Sessions Park. Enjoy local shops, bars, and eateries along the vibrant walkway.

Mission Beach
Spanning nearly two miles of oceanfront, this sandbar community offers sunbathing, surfing, and beach volleyball, with nearby attractions like Belmont Park's Giant Dipper Roller Coaster and SeaWorld in Mission Bay Park.

Gaslamp Quarter
Downtown San Diego's historic district boasts Victorian-era buildings, now housing vibrant restaurants, shops, and entertainment venues. Stroll from Broadway to Harbor Drive, and 4th to 6th Avenue, admiring the newly installed gaslamps at Market Street.

Ocean Beach
Ocean Beach is known for its stunning beaches, and with sights like Ocean Beach and Dog Beach, you won't get bored spending a day wandering around this part of San Diego.
Top Serra Mesa Hotel Reviews

The DEXTRO Little Italy, BW Premier Collection
Frequently asked questions
Explore a world of travel with Expedia
- Clairemont Mesa Hotels
- Hotels with Free Parking in San Diego County
- Luxury Hotels in Pacific Beach
- Hotels near SDSU Transit Center Station
- Guest Houses in San Diego County
- Rv Parks in Central San Diego
- Hotels near Japanese Friendship Garden
- Pet-Friendly Hotels in Old Town San Diego
- Guest Houses in San Diego
- Cheap Hotels in Central San Diego
- Rv Parks in San Diego
- Hotels near Mission San Diego Station
- Hotels with Free Parking in San Diego
- Scuba Diving Hotels in San Diego
- Resorts & Hotels with Spas in Gaslamp Quarter
- Pet-Friendly Hotels in Central San Diego
- Hotels near Balboa Park Carousel
- Hotels near University of San Diego
- Hotels near San Diego Museum of Art
- Hotels near Marston House
- Condo Resorts in Central San Diego
- Hotels near Montgomery Field
- Shopping Hotels in Mission Valley
- Hillcrest Hotels
- Hotels near Marine Corps Air Station Miramar
- Cheap Hotels in North Park
- All-Inclusive Hotel Hotels in Bay Park
- Luxury Hotels in Kearny Mesa
- Mission Valley Hotels
- Business Hotels in Old Town San Diego
- Little Italy Hotels
- Clairemont Hotels
- Pet-Friendly Hotels in Miramar
- Luxury Hotels in North Park
- Hotels near Balboa Park
- Linda Vista Hotels
- Villas in San Diego
- Hotels near Qualcomm Stadium Station
- Cheap Hotels in Downtown San Diego
- Luxury Hotels in Miramar
- Hotels near Mission Bay Park
- Resorts in Morena - Linda Vista Station
- Luxury Hotels in East Village
- Winery Hotels in San Diego
- Cheap Hotels in Point Loma Heights
- Apartments in Fenton Parkway Station
- Residences in Central San Diego
- Hotels near Convoy District
- Hotels near Cal Coast Credit Union Open Air Theater
- Luxury Hotels in Serra Mesa
- Family Hotels in Downtown San Diego
- Hotels near Fashion Valley Transit Center Station
- Cheap Hotels in Gaslamp Quarter
- Cheap Hotels in Little Italy
- Beach Hotels in San Diego County
- Hotels near Mission Valley Mall
- Cheap Hotels in City Heights
- Pacific Beach Hotels
- Pet-Friendly Hotels in San Carlos
- Aparthotels in America Plaza Trolley Station
- Aparthotels in Central San Diego
- Ski Hotels in Mission Valley
- Apartments in San Diego County
- Clairemont Mesa East Hotels
- Pet-Friendly Hotels in San Diego
- Historic Hotels in San Diego
- Winery Hotels in Central San Diego
- Pet-Friendly Hotels in Mission Valley
- Beach Hotels in Mission Valley
- Golf Hotels in San Diego
- Beach Hotels in Pacific Beach
- Cheap Hotels in Mission Beach
- Beach Hotels in Old Town San Diego
- Family Hotels in Linda Vista
- Hotels near Old Town San Diego State Park
- Ski Hotels in North Park
- Resorts in Fiesta Island
- All-Inclusive Hotel Hotels in Mission Valley
- Adults Only Resorts & in San Diego
- Kearny Mesa Hotels
- Business Hotels in Kearny Mesa
- Cheap Hotels in Hillcrest
- Luxury Hotels in San Diego
- Cheap Hotels in Kearny Mesa
- Cheap Hotels in Old Town San Diego
- Cheap Hotels in University City
- Hotels near Fashion Valley Mall
- North Park Hotels
- Inns in San Diego Santa Fe Depot
- Rv Parks in Mission San Diego Station
- Ryokans in San Diego
- Hotels near Hotel Circle

























































































