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Aug 15 - Aug 16
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Aug 16 - Aug 17
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Aug 15 - Aug 17
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Discover 4,491 Medical Center District hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Courtyard by Marriott Medical Center San Antonio
Exterior

Courtyard by Marriott Medical Center San Antonio

3.0 star property
8.8 out of 10, Excellent, (1002)
"Very nice place to stay."
The price is ￥13,693
￥16,187 total
includes taxes & fees
Aug 23 - Aug 24
Courtyard by Marriott Medical Center San Antonio
Fairfield Inn & Suites by Marriott San Antonio Medical Center
Lobby

Fairfield Inn & Suites by Marriott San Antonio Medical Center

2.5 star property
9.0 out of 10, Wonderful, (976)
"Continental breakfast was great, room was very clean both times. "
The price is ￥13,598
￥15,875 total
includes taxes & fees
Aug 24 - Aug 25
Fairfield Inn & Suites by Marriott San Antonio Medical Center
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
Front of property

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

3.0 star property
8.6 out of 10, Excellent, (2864)
"A nice stay for the price. "
The price is ￥13,070
￥15,449 total
includes taxes & fees
Aug 18 - Aug 19
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
San Antonio Marriott Northwest Medical Center
Cocktail bar

San Antonio Marriott Northwest Medical Center

3.5 star property
8.6 out of 10, Excellent, (1000)
"We recommend this hotel 😊"
The price is ￥13,154
￥15,632 total
includes taxes & fees
Aug 31 - Sep 1
San Antonio Marriott Northwest Medical Center
Atria Inn & Suites
Front of property

Atria Inn & Suites

2.0 star property
7.4 out of 10, Good, (247)
"The staff was very friendly."
Atria Inn & Suites
Studio 6 San Antonio, Tx - Northwest Medical Center
Desk, laptop workspace, blackout drapes, free WiFi

Studio 6 San Antonio, Tx - Northwest Medical Center

2.0 star property
7.2 out of 10, Good, (166)
"The location was convenient and the price was very good. "
The price is ￥6,905
￥8,062 total
includes taxes & fees
Sep 14 - Sep 15
Studio 6 San Antonio, Tx - Northwest Medical Center
SpringHill Suites by Marriott San Antonio Medical Center/NW
Premium bedding, pillowtop beds, in-room safe, desk

SpringHill Suites by Marriott San Antonio Medical Center/NW

3.0 star property
8.8 out of 10, Excellent, (1000)
"Always a wonderful stay"
The price is ￥15,371
￥18,170 total
includes taxes & fees
Sep 1 - Sep 2
SpringHill Suites by Marriott San Antonio Medical Center/NW
Drury Inn & Suites San Antonio Northwest Medical Center
Lobby

Drury Inn & Suites San Antonio Northwest Medical Center

3.0 star property
9.2 out of 10, Wonderful, (1265)
"Great location and has complimentary private parking. "
The price is ￥14,779
￥17,469 total
includes taxes & fees
Aug 20 - Aug 21
Drury Inn & Suites San Antonio Northwest Medical Center
Park Inn by Radisson
Reception

Park Inn by Radisson

2.0 star property
7.2 out of 10, Good, (1000)
"Love it "
The price is ￥9,208
￥10,750 total
includes taxes & fees
Sep 15 - Sep 16
Park Inn by Radisson
Motel 6 San Antonio, TX - Northwest Medical Center
Free WiFi, bed sheets

Motel 6 San Antonio, TX - Northwest Medical Center

2.0 star property
6.0 out of 10, (999)
"Really enjoyed our stay"
The price is ￥6,769
￥8,000 total
includes taxes & fees
Sep 14 - Sep 15
Motel 6 San Antonio, TX - Northwest Medical Center
OYO Inn & Suites Medical Center San Antonio
Exterior

OYO Inn & Suites Medical Center San Antonio

2.0 star property
7.2 out of 10, Good, (214)
"Beautiful place to stay love it "
The price is ￥7,981
￥10,501 total
includes taxes & fees
Sep 1 - Sep 2
OYO Inn & Suites Medical Center San Antonio
Flex Studios
Basic Room, Multiple Beds, Non Smoking | 1 bedroom, desk, iron/ironing board, free WiFi

Flex Studios

2.5 star property
6.0 out of 10, (479)
"Great central location in the medical center area, with easy and convenient highway access. "
The price is ￥6,703
￥7,924 total
includes taxes & fees
Aug 29 - Aug 30
Flex Studios
Studio 6 San Antonio, TX - Medical Center
1 bedroom, desk, laptop workspace, free WiFi

Studio 6 San Antonio, TX - Medical Center

2.0 star property
6.6 out of 10, (734)
"Everything perfect"
The price is ￥7,352
￥8,984 total
includes taxes & fees
Sep 15 - Sep 16
Studio 6 San Antonio, TX - Medical Center
Country Inn & Suites by Radisson, San Antonio Medical Center, TX
Free daily on-the-go breakfast

Country Inn & Suites by Radisson, San Antonio Medical Center, TX

3.0 star property
6.6 out of 10, (1000)
"Quick check in and great breakfast"
The price is ￥10,553
￥12,320 total
includes taxes & fees
Sep 2 - Sep 3
Country Inn & Suites by Radisson, San Antonio Medical Center, TX
La Quinta Inn and Suites by Wyndham Schertz-San Antonio-Selma
Premium bedding, down comforters, individually decorated

La Quinta Inn and Suites by Wyndham Schertz-San Antonio-Selma

3.0 star property
8.0 out of 10, Very Good, (1000)
"Great stay and helpful staff. "
The price is ￥12,437
￥14,302 total
includes taxes & fees
Aug 18 - Aug 19
La Quinta Inn and Suites by Wyndham Schertz-San Antonio-Selma
Best Western Plus Atrium Inn
Lobby

Best Western Plus Atrium Inn

2.5 star property
8.8 out of 10, Excellent, (1001)
"Great stay. "
The price is ￥13,290
￥15,284 total
includes taxes & fees
Aug 21 - Aug 22
Best Western Plus Atrium Inn
Super 8 by Wyndham Universal City
Seasonal outdoor pool

Super 8 by Wyndham Universal City

2.0 star property
6.6 out of 10, (1001)
"Great place"
The price is ￥5,653
￥6,487 total
includes taxes & fees
Sep 7 - Sep 8
Super 8 by Wyndham Universal City
stayAPT Suites San Antonio-Randolph
Courtyard

stayAPT Suites San Antonio-Randolph

2.5 star property
8.8 out of 10, Excellent, (379)
"Super nice place to stay - safe, quiet, and the staff was amazing! "
stayAPT Suites San Antonio-Randolph
Best Western Garden Inn
Reception

Best Western Garden Inn

2.5 star property
8.2 out of 10, Very Good, (1003)
"We enjoyed our stay here"
The price is ￥10,007
￥11,683 total
includes taxes & fees
Sep 1 - Sep 2
Best Western Garden Inn
La Quinta by Wyndham San Antonio by Frost Bank Center
Exterior

La Quinta by Wyndham San Antonio by Frost Bank Center

3.0 star property
7.8 out of 10, Good, (1002)
"Amazing place to stay "
The price is ￥10,508
￥12,268 total
includes taxes & fees
Aug 17 - Aug 18
La Quinta by Wyndham San Antonio by Frost Bank Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Medical Center District

Find the best Medical Center District areas and neighborhoods for the activities you enjoy most. Learn more about Medical Center District
Learn more about Medical Center District
Downtown - Riverwalk which includes heritage architecture, boating and a river or creek
Downtown San Antonio map

Downtown San Antonio

Explore the heart of San Antonio with top attractions like the Alamo and River Walk, or enjoy kayaking and bicycling to the World Heritage Missions. Discover historic sites, theaters, and shopping at Rivercenter, all easily accessible by public transit.

Far West Side map

Far West Side

While visiting Far West Side, you might make a stop by sights like Aquatica San Antonio Waterpark and Hill Country Golf Club.

Marion Koogler McNay Art Museum featuring art and interior views
Uptown map

Uptown

While visiting Uptown, you might make a stop by sights like Marion Koogler McNay Art Museum and Alamo Quarry Market.

Stone Oak map

Stone Oak

Travelers come to Stone Oak for its abundant dining options, and you can see top attractions like Shops at Hardy Oak and Alta Vista while you're in town.

Northwest Side map

Northwest Side

While visiting Northwest Side, you might make a stop by sights like Huebner Oaks and Convocation Center.

Top Medical Center District Hotel Reviews

Hotel Valencia Riverwalk

Hotel Valencia Riverwalk

10/10 Excellent
"It was a great stay! Best hotel we've stayed at in San Antonio. "
Adrian 1-night trip
Posted 15 hours ago
Hotel Valencia Riverwalk

Frequently asked questions

What is Medical Center District like?

Travelers are sure to enjoy a stay in San Antonio's Medical Center District neighborhood. Are you looking for Medical Center District travel tips? Be sure to check out USAA Corporate Office Headquarters and Cinemark San Antonio 16 while you're in the neighborhood.

What's a favorite place to stay in Medical Center District?

Based on Expedia customer reviews, Drury Inn & Suites San Antonio Northwest Medical Center is the highest ranked property in Medical Center District. This hotel offers free breakfast and an indoor pool. Other favorite options in the area include SpringHill Suites by Marriott San Antonio Medical Center/NW and Fairfield Inn & Suites by Marriott San Antonio Medical Center.

How many hotels will I be able to find in Medical Center District?

Expedia has 114 hotels and other accommodations in Medical Center District to choose from, making this an ideal home base for exploring the greater San Antonio area.

If I need to cancel my hotel reservation in Medical Center District, will I receive a refund?

Yes! You'll find that most hotel bookings are refundable provided that you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of the scheduled arrival. If you booked a non-refundable reservation, you might be able to cancel it and be given a refund within a 24-hour period of your booking. Enter your dates, click on "Search", then use the filter option "fully refundable" to view top deals in Medical Center District.

Where can I learn more about changing or cancelling my trip to Medical Center District?

For more information about changing or cancelling your trip to Medical Center District, go to https://www.expedia.com/service/.

What can I see and do in this San Antonio neighborhood?

USAA Corporate Office Headquarters, Cinemark San Antonio 16, and The San Antonio Art Institute are just a few attractions to check out in Medical Center District. Wonderland of the Americas Mall and First Unitarian Universalist Church are also worth a visit when you're out sightseeing in San Antonio.