Find hotels in Medical Center, Detroit

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
Apr 1 - Apr 2
Tomorrow
Apr 2 - Apr 3
This weekend
Apr 3 - Apr 5
Next weekend
Apr 10 - Apr 12

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Medical Center hotels

Blackout drapes, iron/ironing board, WiFi, bed sheets

Holiday Inn Express & Suites Detroit North - Roseville by IHG

Holiday Inn Express & Suites Detroit North - Roseville by IHG
2.5 star property
21.3 km from Medical Center
8.0 out of 10, Very Good, (685 reviews)
"Good stay"
Canada
Rajesh Kumar
The price is ￥14,762
￥16,312 total
includes taxes & fees
Apr 5 - Apr 6
Holiday Inn Express & Suites Detroit North - Roseville by IHG
Free daily on-the-go breakfast

avid hotel Detroit Warren by IHG

avid hotel Detroit Warren by IHG
2.5 star property
15.7 km from Medical Center
9.0 out of 10, Wonderful, (1,186 reviews)
"Comfortable stay; great breakfast. "
United States
Desiree
The price is ￥13,016
￥14,859 total
includes taxes & fees
Apr 22 - Apr 23
avid hotel Detroit Warren by IHG
Breakfast, lunch, dinner served; American cuisine

Comfort Inn Detroit Downtown

Comfort Inn Detroit Downtown
2.5 star property
Elmwood Park, 3.1 km from Medical Center
7.2 out of 10, Good, (1,002 reviews)
"clean room nice ppl shuttle to game offered "
United States
KRISTINA
The price is ￥17,633
￥19,565 total
includes taxes & fees
Apr 6 - Apr 7
Comfort Inn Detroit Downtown
Premium bedding, in-room safe, desk, laptop workspace

Hollywood Casino at Greektown

Hollywood Casino at Greektown
4.0 star property
Greektown Historic District, 2.4 km from Medical Center
8.6 out of 10, Excellent, (5,070 reviews)
"Very clean hotel and friendly staff and in a great location."
Canada
David
The price is ￥19,885
￥27,446 total
includes taxes & fees
Apr 8 - Apr 9
Hollywood Casino at Greektown
Pool

Courtyard By Marriott Detroit Downtown

Courtyard By Marriott Detroit Downtown
3.5 star property
Downtown Detroit, 2.9 km from Medical Center
8.4 out of 10, Very Good, (1,001 reviews)
"The staff were incredible, hotel amenities were great, rooms were clean and very comfortable. When I return to Detroit, this will be the only hotel I stay at. "
Canada
Amanda
The price is ￥26,849
￥31,146 total
includes taxes & fees
Apr 20 - Apr 21
Courtyard By Marriott Detroit Downtown
Lobby

Atheneum Suite Hotel

Atheneum Suite Hotel
4.0 star property
Greektown Historic District, 2.5 km from Medical Center
9.2 out of 10, Wonderful, (2,155 reviews)
"The hotel was awesome and perfect location "
United States
guy
The price is ￥22,869
￥26,529 total
includes taxes & fees
Apr 5 - Apr 6
Atheneum Suite Hotel
Exterior

La Quinta Inn & Suites by Wyndham Detroit Utica

La Quinta Inn & Suites by Wyndham Detroit Utica
3.0 star property
30.6 km from Medical Center
7.8 out of 10, Good, (1,344 reviews)
"From the moment I entered the building there was nothing but excellence every step was excellent no complaints at all very clean very friendly very professional very nice place to stay would highly recommend this"
United States
Cheryl
The price is ￥11,468
￥12,672 total
includes taxes & fees
Apr 13 - Apr 14
La Quinta Inn & Suites by Wyndham Detroit Utica
Terrace/patio

Sonesta ES Suites Detroit Warren

Sonesta ES Suites Detroit Warren
3.0 star property
18 km from Medical Center
7.8 out of 10, Good, (834 reviews)
"Great room at a tremendous price! "
United States
Anthony
The price is ￥15,873
￥17,540 total
includes taxes & fees
Apr 28 - Apr 29
Sonesta ES Suites Detroit Warren
Exterior

Hilton Garden Inn Detroit Downtown

Hilton Garden Inn Detroit Downtown
3.0 star property
Downtown Detroit, 2.2 km from Medical Center
8.6 out of 10, Excellent, (1,004 reviews)
"Great place to stay and walk to games and restaurants. "
United States
Tyler
The price is ￥24,151
￥28,014 total
includes taxes & fees
Apr 5 - Apr 6
Hilton Garden Inn Detroit Downtown
Breakfast, lunch, dinner served; American cuisine

Fort Pontchartrain Detroit, a Wyndham Hotel

Fort Pontchartrain Detroit, a Wyndham Hotel
3.5 star property
Downtown Detroit, 3.1 km from Medical Center
8.6 out of 10, Excellent, (2,413 reviews)
"It was a great stay! The staff was very friendly and it was so fancy inside. The rooms were cozy and well kept. "
Canada
Molly
The price is ￥22,802
￥26,449 total
includes taxes & fees
Apr 19 - Apr 20
Fort Pontchartrain Detroit, a Wyndham Hotel
Exterior

Holiday Inn Express Detroit-Warren by IHG

Holiday Inn Express Detroit-Warren by IHG
2.5 star property
15.6 km from Medical Center
8.6 out of 10, Excellent, (1,001 reviews)
"Hotel was nice, employees were friendly, professional and helpful. Breakfast was excellent as well"
United States
maria
The price is ￥13,744
￥15,186 total
includes taxes & fees
Apr 6 - Apr 7
Holiday Inn Express Detroit-Warren by IHG
Restaurant

Detroit Foundation Hotel

Detroit Foundation Hotel
4.0 star property
Downtown Detroit, 3 km from Medical Center
9.4 out of 10, Exceptional, (1,000 reviews)
"Inviting hotel with beautiful vintage decor, clean spaces, friendly staff and delicious food!"
United States
LaNaye
The price is ￥42,639
￥49,715 total
includes taxes & fees
Apr 12 - Apr 13
Detroit Foundation Hotel
Lobby

Quality Inn & Suites Warren - Detroit

Quality Inn & Suites Warren - Detroit
2.5 star property
18.5 km from Medical Center
7.8 out of 10, Good, (1,004 reviews)
"my stay was comfortable the staff was pleasant the room was clean i definitely recommend that if you’re in warren and need a room that’s the place for you "
United States
sharmara
The price is ￥9,984
￥11,033 total
includes taxes & fees
Apr 26 - Apr 27
Quality Inn & Suites Warren - Detroit
4 restaurants, breakfast served

Shinola Hotel

Shinola Hotel
4.0 star property
Downtown Detroit, 2.3 km from Medical Center
9.6 out of 10, Exceptional, (1,177 reviews)
"Clean room, friendly staff "
United States
Satsantokh
The price is ￥42,382
￥52,939 total
includes taxes & fees
Apr 23 - Apr 24
Shinola Hotel
Check-in/check-out kiosk

The Siren Hotel, an Ash Hotel

The Siren Hotel, an Ash Hotel
4.0 star property
Downtown Detroit, 2.2 km from Medical Center
9.0 out of 10, Wonderful, (1,871 reviews)
"Everyone was so helpful and kind. I would stay there again."
United States
Kelli
The price is ￥16,576
￥18,732 total
includes taxes & fees
Apr 7 - Apr 8
The Siren Hotel, an Ash Hotel
Free daily buffet breakfast

Wingate by Wyndham Utica

Wingate by Wyndham Utica
2.5 star property
30.5 km from Medical Center
8.4 out of 10, Very Good, (1,000 reviews)
"Clean rooms and friendly staff"
United States
george
The price is ￥12,225
￥13,510 total
includes taxes & fees
Apr 2 - Apr 3
Wingate by Wyndham Utica
Property amenity

Staybridge Suites Sterling Heights - Detroit by IHG

Staybridge Suites Sterling Heights - Detroit by IHG
3.0 star property
22.1 km from Medical Center
9.4 out of 10, Exceptional, (341 reviews)
"Breakfast was good.room was clean and the surrounding area of the hotel is very nice and has everything u need "
Canada
Ezra
The price is ￥22,802
￥25,196 total
includes taxes & fees
Apr 2 - Apr 3
Staybridge Suites Sterling Heights - Detroit by IHG
Dinner served, American cuisine

The Detroit Club

The Detroit Club
4.0 star property
Downtown Detroit, 2.8 km from Medical Center
9.0 out of 10, Wonderful, (369 reviews)
"The only problem we had that r tv didn’t work in the room but the staff the food and everyone made u feel so comfortable i will make reservations back to stay there again"
United States
Doralinda
The price is ￥22,550
￥30,025 total
includes taxes & fees
Apr 12 - Apr 13
The Detroit Club
Exterior

Hotel Indigo Detroit Downtown by IHG

Hotel Indigo Detroit Downtown by IHG
3.5 star property
Downtown Detroit, 2.6 km from Medical Center
8.4 out of 10, Very Good, (1,193 reviews)
"Wonderful hotel"
United States
Jeff
The price is ￥23,492
￥27,251 total
includes taxes & fees
Apr 19 - Apr 20
Hotel Indigo Detroit Downtown by IHG
1 Bedroom Queen Apartment | In-room dining

Hotel Houze Detroit Downtown

Hotel Houze Detroit Downtown
3.0 star property
Downtown Detroit, 2.6 km from Medical Center
8.0 out of 10, Very Good, (201 reviews)
"LOVED my stay here, will be back for every Detroit trip."
United States
Mackenzie
The price is ￥14,450
￥16,327 total
includes taxes & fees
Apr 19 - Apr 20
Hotel Houze Detroit Downtown
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Where to stay in Medical Center

Find the best Medical Center areas and neighborhoods for the activities you enjoy most.

Downtown Detroit

Central business district meets residential area, Downtown Detroit boasts historic architecture, skyscrapers, and parks. Explore attractions like Campus Martius Park, Fox Theatre, and Detroit Riverwalk, with convenient transport options nearby.

Photo by Jw
Open Photo by Jw

Rochester Hills

Live music, restaurants, and shopping are just a few things travelers enjoy about Rochester Hills. Check out The Village Of Rochester Hills or Meadow Brook Amphitheatre while you're exploring the area.

Historic buildings in Downtown Detroit - Michigan, United States

Midtown

Historic districts and cultural attractions abound in this area, with highlights like the Detroit Institute of Arts and the Charles H. Wright Museum of African American History. Independent retail outlets are on the rise, especially along the Cass Corridor.

Detroit old train station under renovation in December 2019. Iconic building in downtown Detroit, Michigan

Corktown

Discover Detroit's oldest neighborhood, featuring historic Federal-style homes and charming Irish businesses. Enjoy a stay at the Trumbull & Porter boutique hotel or explore the walkable Mobility Innovation District around Michigan Central Station.

Photo by Terry Fletcher
Open Photo by Terry Fletcher

Brush Park

Brush Park might not have many top sights, but Comerica Park and Little Caesars Arena are two attractions nearby that you can check out.

Top Medical Center Hotel Reviews

MGM Grand Detroit

MGM Grand Detroit

10/10 Excellent
"valet parking was fast and efficient process. Staff through-out the premises was very polite and helpful."
rachel 2-night trip
Posted 5 hours ago
MGM Grand Detroit

Frequently asked questions

What's it like in Medical Center?
Travelers to the Medical Center neighborhood in Detroit will be sure to enjoy their stay. Be sure to check out Cultural Center Historic District and Lexus Velodrome as part of your Medical Center travel plans.
If I need to cancel my hotel reservation in Medical Center, will I receive a refund?
Yes, you'll find most hotel reservations are refundable if you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of check in. If your reservation is non-refundable, you might be able to cancel it and receive a refund within 24 hours of your booking. Add your dates and click on "Search", then you can use the "fully refundable" filter to view the best deals in Medical Center.
Where can I learn more about changing or cancelling my trip to Medical Center?
For additional details about rescheduling or cancelling your trip to Medical Center, head over to our customer service page.
What is there to do in this Detroit neighborhood?
A few attractions you might want to check out while you're in Medical Center are Cultural Center Historic District and Lexus Velodrome. Comerica Park and The Majestic Theatre are also worth a visit when you're out sightseeing in Detroit.

Explore a world of travel with Expedia