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Top Kid friendly Southeast Missouri Hotels

Drury Inn & Suites Sikeston, MO

2608 East Malone Ave, Miner Sikeston MO

4 hours drive from Johnson's Shut-ins State Park

Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...

9.6/10 Exceptional! (1,000 reviews)

"This was a wonderful stay for the night while traveling. Thankful for the recommendation from the front desk to eat at Lamberts restaurant 3 minutes down the road. So fun!"

Reviewed on Jun 15, 2026

Best Western Plus Sikeston I-55

120 S Interstate Drive Sikeston MO

4 hours drive from Johnson's Shut-ins State Park

Stay at this hotel in Sikeston. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the breakfast and the helpful staff in our reviews. ...

8.4/10 Very Good! (1,015 reviews)

"Good price, just a little dated and a few dead bugs in the room."

Reviewed on Jun 18, 2026

Drury Inn & Suites Cape Girardeau

3303 Campster Drive Cape Girardeau MO

4 hours drive from Johnson's Shut-ins State Park

Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...

9.4/10 Exceptional! (1,001 reviews)

"The room was very clean, loved the shower. Didn't get to use the pool or hot tub due to too many people. I did not get to enjoy the breakfast because I had to leave before breakfast time. My favorite room is the suites."

Reviewed on Jun 17, 2026

See all 661 properties in Southeast Missouri

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.