The Best Historic Hotels in Uptown, OH from ￥21,400 in 2026

A historic building with ornate architecture and a modern brick structure in the foreground.

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Our top choices for Uptown historic hotels

A living room with a grey sofa, a wooden coffee table, a patterned rug, a patterned armchair, and large windows with a view of houses and trees.

1. Prime Walk to Cincinnati Zoo & Botanical Garden –Steps to UC, Short Vine & More!

Clifton

"Our stay at this beautiful home was nothing short of amazing! From the moment we arrived, the host was incredibly attentive and went above and beyond to make sure we had everything we needed. There wasn't a single want or need that wasn't met—it truly felt like a home away from home. The home was beautiful, comfortable, and made our trip even more enjoyable. Thank you again for such an incredible experience. We can't wait to book with you again on our next visit. Highly recommend! "

Talya B.

￥79,364 total

includes taxes & fees

Oct 29 - Oct 30

A grand hall with ornate chandeliers, a central staircase, and a seating area with patterned upholstery.

2. Hilton Cincinnati Netherland Plaza

Downtown Cincinnati

Margielyn Peladas

￥21,400 total

includes taxes & fees

Nov 22 - Nov 23

A cozy lounge area with wooden flooring, cushioned seating, and hanging pendant lights.

3. The Cincinnatian Hotel Curio Collection by Hilton

Downtown Cincinnati

Maria

￥26,830 total

includes taxes & fees

Nov 3 - Nov 4

A wooden deck with a table and chairs, overlooking a grassy area and a cityscape.

4. Great views in OTR, lots of parking & big yard!

Over-the-Rhine

Carol J.

￥25,348 total

includes taxes & fees

Nov 19 - Nov 20

A hallway leading to a living area with a sofa, chairs, and a table.

5. Hip Eclectic 1 Bedroom In OTR

Downtown Cincinnati

Emma K.

￥28,664 total

includes taxes & fees

Nov 8 - Nov 9

A living room with a black sofa, two armchairs, a glass coffee table, and a brick wall.

6. Historic OTR on Main Street, Central to all and Free Parking

Downtown Cincinnati

Renee

￥33,483 total

includes taxes & fees

Nov 19 - Nov 20

A bedroom with a brick wall, a bed with white bedding, a chandelier, a flat-screen TV, and a kitchenette.

7. NEWPORT INN #4 - NO CLEANING FEES!! FREE PARKING!! WALK TO GAMES AND CONCERTS!!

Two Rivers

Blaire S.

￥25,658 total

includes taxes & fees

Oct 29 - Oct 30

A house with a porch, steps, and a mailbox.

8. 2 Bedroom House in the Heart of Northside, Close to Everything in Cincinnati

Northside

Jeffrey F.

￥33,404 total

includes taxes & fees

Nov 11 - Nov 12

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Top Uptown Hotel Reviews

Hotel Covington Cincinnati Riverfront

10/10 Excellent

"charming hotel in a small city in the central entertainment district."

21c Museum Hotel Cincinnati

8/10 Good

"The hotel itself was great, and I love the museum theme. The room was comfortable, modern. and really nice. The weak spot was the staff. Everything from a front deck staff that seemed more interested in their computers than helping us, and valets who took 20-30 minutes to get our car. The biggest pain isn't the fault of the hotel but while they are a pet-friendly hotel, there isn't a single plot of grass anywhere within 10 blocks of the hotel. The staff was well aware telling us "there is no where to take your dog' but at the same time didn't to anything to create a solution. Something as simple as a square of astroturf would have made our lives so much easier."

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Our top choices for Uptown historic hotels