Photo by Visit Greenville, South Carolina

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Check prices for these dates

Next weekend
Nov 13 - Nov 15
In two weeks
Nov 20 - Nov 22
In one month
Dec 4 - Dec 6
In two months
Jan 1 - Jan 3

Our top choices for Upstate South Carolina villas

A two-story white house with a front porch, a stone foundation, and a brick staircase leading to the entrance.

1. Grand Southern Elegance near Downtown Pickens

Grand Southern Elegance near Downtown Pickens
Pickens
10.0 out of 10, Exceptional, (1 review)
"This home is perfectly put together for a group to enjoy their time. It combines the history of the house and the new features that make it comfortable. Property is very clean, warm and welcoming. The host was very welcoming and accommodating for us."
United States
John B.
The price is ￥170,089
￥280,926 total
includes taxes & fees
Nov 16 - Nov 17
Grand Southern Elegance near Downtown Pickens
A covered outdoor seating area with wicker chairs and a table, overlooking a wooden deck and leafless trees.

2. Hartwell Nest • 25 mins to Clemson • Next to Lake

Hartwell Nest • 25 mins to Clemson • Next to Lake
Westminster
The price is ￥21,261
￥47,641 total
includes taxes & fees
Nov 11 - Nov 12
Hartwell Nest • 25 mins to Clemson • Next to Lake
A table with two drinks and a hat, overlooking a mountainous landscape.

3. Indoor Pool Resort • Hot Tub + Sauna • Rooftop • Speakeasy • Caboose

Indoor Pool Resort • Hot Tub + Sauna • Rooftop • Speakeasy • Caboose
Pisgah Forest
10.0 out of 10, Exceptional, (1 review)
"The Canopy Club was truly an amazing experience for our family vacation/retreat. Perfect location just outside of Brevard and the Pisgah Mountains and conveniently located to so many scenic sites. The views from this home are phenomenal! All the exterior porches are amazing for relaxing and catching the morning fog rising under the mountains to sunset beautiful ski lines at night. The home is exactly as described and shown. We enjoyed all the recreational areas, pool and spa. The owners were...
United States
Emily H.
The price is ￥58,056
￥283,659 total
includes taxes & fees
Nov 11 - Nov 12
Indoor Pool Resort • Hot Tub + Sauna • Rooftop • Speakeasy • Caboose
Exterior

4. The Onyx- Walk to Falls, Hot Tub, Near Golf, Resort Access

The Onyx- Walk to Falls, Hot Tub, Near Golf, Resort Access
Sapphire
10.0 out of 10, Exceptional, (3 reviews)
"The house was beautiful and very comfortable and clean. Our host was extremely accessible. Absolutely loved our stay."
United States
Alison M.
The price is ￥49,128
￥88,798 total
includes taxes & fees
Nov 8 - Nov 9
The Onyx- Walk to Falls, Hot Tub, Near Golf, Resort Access
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Learn more about Upstate South Carolina

Experience the family-friendly area of Upstate South Carolina—live music, restaurants, and sights from Discovery Island Water Park to Frankie's Fun Park.

See all hotels in Upstate South Carolina
An aerial view of a park with a winding path, trees in autumn colors, and a bridge.
Photo by Visit Greenville, South Carolina
Open Photo by Visit Greenville, South Carolina

Top reviews in Upstate South Carolina

A large, two-story house with a symmetrical facade, large windows, and a central entrance.
Hotel Hartness

Hotel Hartness

Hotel Hartness
Greenville

10/10 Excellent

The hotel is top notch. The rooms were thoughtfully decorated and there were many amenities. Breakfast was wonderful.
United States
Gracie
Reviewed April 22, 2025
Hotel Hartness

Frequently Asked Questions

How much do villas in Upstate South Carolina cost?

Prices for villas in Upstate South Carolina range between ￥21,261 and ￥170,089 per night. No matter your budget, you're sure to find something that matches your needs on Expedia. These prices were available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.

Why book your villa in Upstate South Carolina with Expedia?

Booking a villa in Upstate South Carolina is as simple as working out your travel dates and selecting an option that meets your needs. Seeking something budget friendly or upmarket, or a stay that also features a pool and free WiFi? Use Expedia's search filters to narrow your results and find your perfect match.

How can I find cheap villas in Upstate South Carolina?

With Expedia's handy filter tool, scoring cheap villas in Upstate South Carolina is a piece of cake. To find stays that give you the most bang for your buck, narrow down your search by budget, amenities and star rating.

What is there to do near my villa in Upstate South Carolina?

You'll find tons of ways to fill your days in Upstate South Carolina. If you're visiting Greenville, don't miss Sirrine Stadium, Greenville Cultural Exchange Center and Cleveland Park. Basing yourself in Spartanburg? Chapman Cultural Center, Spartanburg Memorial Auditorium and Spartanburg Regional Hospital are popular sights here.

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