Find Boutique Hotels in Upstate South Carolina, SC

Start date: Check-in selected.
To Date
End date: Check-out
    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check availability on Upstate South Carolina Boutique Hotels

This weekend
Next weekend

Top Upstate South Carolina Boutique Hotels

Our top choices for Upstate South Carolina boutique hotels

Hotel Domestique

4.0 star property
9.6 out of 10, Exceptional, (30)
"Overall it was an exceptional experience and would highly recommend to anyone looking for a quiet get away."
The price is ¥67,799
¥74,579 total
includes taxes & fees
Sep 25 - Sep 26
Hotel Domestique

Inn @ Clemson

2.5 star property
8.0 out of 10, Very Good, (1022)
"Good location"
Inn @ Clemson

The Bleckley Inn

3.5 star property
9.8 out of 10, Exceptional, (404)
"Lovely hotel in Anderson. Very accommodating staff. "
The price is ¥27,653
¥30,695 total
includes taxes & fees
Oct 22 - Oct 23
The Bleckley Inn

Hyatt Place Greenville/Haywood

3.0 star property
7.8 out of 10, Good, (1010)
"great hotel"
The price is ¥14,171
¥16,057 total
includes taxes & fees
Sep 30 - Oct 1
Hyatt Place Greenville/Haywood
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Upstate South Carolina Hotel Reviews

Explore a world of travel with Expedia

Explore a world of travel with Expedia