Find Resorts & Hotels with Spas in Santa Fe, TX

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Santa Fe Resorts & Hotels with Spas

Tonight
Dec 20 - Dec 21
Tomorrow
Dec 21 - Dec 22
Next weekend
Dec 26 - Dec 28
In two weeks
Jan 2 - Jan 4

Our top choices for Santa Fe hotels with a spa

Couples treatment rooms, sauna, hot tub, body treatments, hydrotherapy
Moody Gardens Hotel, Spa and Convention Center

Moody Gardens Hotel, Spa and Convention Center

Moody Gardens Hotel, Spa and Convention Center
4.0 star property
Near West End
8.8 out of 10, Excellent, (1955)
"The staff was really nice when we checked in. "
United States
Patricia
The price is ￥14,068
￥16,178 total
includes taxes & fees
Jan 14 - Jan 15, 2026
Moody Gardens Hotel, Spa and Convention Center
Outdoor pool
Holiday Inn Resort: Galveston-On The Beach by IHG

Holiday Inn Resort: Galveston-On The Beach by IHG

Holiday Inn Resort: Galveston-On The Beach by IHG
3.5 star property
Midtown
8.4 out of 10, Very Good, (1003)
"Very clean and the staff was beyond kind and lovely!"
United States
Samantha
The price is ￥17,297
￥19,892 total
includes taxes & fees
Dec 21 - Dec 22
Holiday Inn Resort: Galveston-On The Beach by IHG
Steam room, body treatments, hydrotherapy, aromatherapy
Grand Galvez Resort, Autograph Collection

Grand Galvez Resort, Autograph Collection

Grand Galvez Resort, Autograph Collection
4.0 star property
San Jacinto
8.8 out of 10, Excellent, (1276)
"The Christmas decorations were beautiful and the staff was excellent. "
United States
Cedric
The price is ￥24,997
￥28,747 total
includes taxes & fees
Dec 24 - Dec 25
Grand Galvez Resort, Autograph Collection
Spa reception
South Shore Harbour Resort & Conference Center

South Shore Harbour Resort & Conference Center

South Shore Harbour Resort & Conference Center
3.5 star property
League City
9.0 out of 10, Wonderful, (1002)
"Generous facility, large room, good restaurant, helpful staff"
United States
Gerhard
The price is ￥15,956
￥18,031 total
includes taxes & fees
Dec 21 - Dec 22
South Shore Harbour Resort & Conference Center
Couples treatment rooms, sauna, hot tub, body treatments, hydrotherapy
The San Luis Resort, Spa & Conference Center

The San Luis Resort, Spa & Conference Center

The San Luis Resort, Spa & Conference Center
4.0 star property
Midtown
9.0 out of 10, Wonderful, (1155)
"Great location for great food!"
United States
Dorothy
The price is ￥35,955
￥44,976 total
includes taxes & fees
Dec 28 - Dec 29
The San Luis Resort, Spa & Conference Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Santa Fe Hotel Reviews

Moody Gardens Hotel, Spa and Convention Center

Moody Gardens Hotel, Spa and Convention Center

10/10 Excellent
"Nice hotel with good amenities and very clean room. Fair pricing. Only complaint: Add some softer pillows"
Niels H 1-night trip
Posted 2 days ago
Moody Gardens Hotel, Spa and Convention Center

Frequently asked questions

Looking to vacation at a spa hotel in Santa Fe?
Book one of our fantastic spa hotels and treat yourself from the moment you arrive. Check out the beaches in Santa Fe - worth a picture or two! Spa hotels are a great way to take a break from your daily routine and add a layer of luxury to your vacation.
What's there to see and do in Santa Fe?
Experience all that Santa Fe has to offer when you visit Haak Vineyards and Winery, LagoonFest, and Jack Brooks Park. If you have a little extra time during your trip, you might want to check out NASA Johnson Space Center and Tanger Outlets.
What is a Santa Fe spa hotel?
Spa hotels in Santa Fe feature full on-site spas offering services such as facials and a selection of beauty treatments. Some also provide a selection of in-room treatments for the ultimate luxury. Spa hotels are great for rest, rejuvenation, and relaxation.

Explore a world of travel with Expedia