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Check availability on Santa Cruz Casinos

Our top choices for Santa Cruz hotels with a casino

Swissôtel Santa Cruz De La Sierra

Swissôtel Santa Cruz De La Sierra
4.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (81)
"Beautiful hotel"
Australia
Joanna
The price is ¥23,013
¥23,013 total
Jan 12 - Jan 13, 2026
Swissôtel Santa Cruz De La Sierra

Cozy studio in enchanting Santa Cruz de la Sierra with WiFi, AC

Cozy studio in enchanting Santa Cruz de la Sierra with WiFi, AC
Santa Cruz de la Sierra
The price is ¥2,805
¥6,700 total
Dec 16 - Dec 17
Cozy studio in enchanting Santa Cruz de la Sierra with WiFi, AC
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find out more about Santa Cruz

Discover top Santa Cruz attractions

In Santa Cruz, Bolivia, travelers with a penchant for casinos will find an exciting blend of leisure and entertainment. Start your journey with a visit to the Casino Royal, one of the premier gaming venues in the city, featuring a vibrant atmosphere with a variety of gaming options from slots to poker tables. Just a short stroll away, you can explore the lively Plaza 24 de Septiembre, where you can enjoy local street food and immerse yourself in the cultural vibe of Santa Cruz. For a more upscale experience, head to the luxurious Ventura Mall, which not only boasts a selection of high-end shops but also features a casino on-site, perfect for those looking to combine shopping with gaming. After a day of excitement, unwind at one of the chic hotels in the Equipetrol area, known for its trendy nightlife and dining options. Here, you can enjoy modern amenities and attentive service, ensuring a comfortable retreat after a thrilling evening at the tables. Experience the best of both worlds as you explore the dynamic atmosphere of Santa Cruz while indulging in your love for casinos.

Top Santa Cruz Hotel Reviews

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Frequently asked questions

Searching for casino hotels in Santa Cruz?
Visitors have good things to say about the shopping in this destination.
How many hotels that are good for gaming will I find in Santa Cruz?
Practice your poker face at one of Expedia's 285 accommodations near casino gaming in Santa Cruz.
When should I take my casino trip to Santa Cruz?
You'll likely spend much of your trip indoors, but if you're planning to venture beyond the casino, looking at local weather trends is a good idea. The hottest months are usually October and November with an average temp of 79°F, while the coldest months are June and July with an average of 70°F. Average annual precipitation for Santa Cruz is 48 inches.
What is there to do in Santa Cruz?
You can head to Ventura Mall, La Recova Artisan Walk, or Artecampo to shop for the perfect souvenir. Check out Cine Center, Ethno-folkloric Museum, or Sacred Art Museum for a taste of local culture. If you're looking to add to your itinerary, you can also visit Plaza 24 de Septiembre and Ramon Tahuichi Aguilera Stadium.
What are my transportation options for my casino getaway to Santa Cruz?
Here are some transportation options in Santa Cruz: You can arrange a flight to the closest airport, which is Santa Cruz (VVI-Viru Viru Intl.), located 9.8 mi (15.8 km) from the city center. To venture out into the surrounding area, hop aboard a train at Santa Cruz de la Sierra Station.