Find 4 Star Hotels in Santa Cruz from ¥11,672

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Our top choices for Santa Cruz 4-star hotels

Camino Real Hotel

Camino Real Hotel
4.5 star property
Santa Cruz
8.8 out of 10, Excellent, (412 reviews)
"The parrots. Unique"
United States
Juan P
The price is ¥28,610
¥28,610 total
Jan 18 - Jan 19
Camino Real Hotel

TRYP by Wyndham Santa Cruz

TRYP by Wyndham Santa Cruz
4.0 star property
Santa Cruz
9.2 out of 10, Wonderful, (149 reviews)
"The hotel is well located, convenient for restaurants and shopping, and very quiet. We stayed in a 2-bedroom suite, very well appointed and comfortable. Love the design of the corridor! Staff are friendly and helpful. A bar at the dining area where breakfast is would be great."
United States
Vivian
The price is ¥15,700
¥15,700 total
Jan 18 - Jan 19
TRYP by Wyndham Santa Cruz

Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

Hampton by Hilton Santa Cruz/Equipetrol, Bolivia
4.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (259 reviews)
"Nice hotel "
United States
Narciso Lorenzo
The price is ¥11,672
¥11,672 total
Feb 1 - Feb 2
Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

Swissôtel Santa Cruz De La Sierra

Swissôtel Santa Cruz De La Sierra
4.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (82 reviews)
"Beautiful hotel"
Australia
Joanna
The price is ¥19,950
¥19,950 total
Jan 31 - Feb 1
Swissôtel Santa Cruz De La Sierra

Hotel Maywa

Hotel Maywa
4.0 star property
Santa Cruz
9.2 out of 10, Wonderful, (10 reviews)
"The structure and service was fantastic"
United States
Alex
Hotel Maywa

Buganvillas Hotel Suites & Spa

Buganvillas Hotel Suites & Spa
4.0 star property
Santa Cruz
7.4 out of 10, Good, (93 reviews)
"The correct description would be that it is a Air & B without a Stowe/owen/kitchen supplies but with a refrigerator. What they claim at the web page IS NOT correct. The pool is correct and there is a restaurant, a one man show. We were the only ones at breakfast, one day no one was even there. A scam. Majority are residents in this complex. The ladies at the receptions was sweet though and did their best. "
Sweden
Charlotte
Buganvillas Hotel Suites & Spa

Royal Lodge Hotel

Royal Lodge Hotel
4.5 star property
Santa Cruz
6.4 out of 10, (29 reviews)
"Esta cerrado, ya no deberia dejar reservar, se nota q tiene tiempo fuera de servicio."
Argentina
Anonymous traveler
Royal Lodge Hotel
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Explore similar 5-star hotels

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Santa Cruz

Tropical energy pulses through Plaza 24 de Septiembre, where locals gather under palm trees and the Metropolitan Cathedral's twin towers stand watch. Biocentro Güembé offers rainforest trails with butterfly gardens, while the massive Ventura Mall provides air-conditioned shopping when afternoon temperatures climb.

San Lorenzo Cathedral showing a garden

Top Santa Cruz Hotel Reviews

Frequently asked questions

What are the best 4-star hotels in Santa Cruz?
If you're seeking luxury comfort and loads of amenities during your Santa Cruz retreat, consider TRYP by Wyndham Santa Cruz. This 4-star hotel offers a spa tub and a terrace. Hampton by Hilton Santa Cruz/Equipetrol, Bolivia also gets stellar reviews from Expedia guests. Concierge services and a garden are among its conveniences.
How much does it cost to stay in a 4-star hotel in Santa Cruz?
Expedia can help you easily locate the perfect 4-star hotel for your vacation in Santa Cruz. Use our filter tool to tailor your search by things like price, conveniences and star rating and get access to terrific deals in a few clicks.

  • Search for the lowest price from ¥15,475

What's the difference between 5-star and 4-star hotels in Santa Cruz?
If you choose to spend your vacation at a 4-star hotel in Santa Cruz, you'll typically find plenty of conveniences to ensure you're comfortable, such as a restaurant, gym and pool. You can enjoy top-quality service and deluxe accommodations. Choose a 5-star hotel and you'll get a few extra perks — think concierge assistance, on-site spas and opulent turndown services. You're likely to get more amenities and premium services at a 5-star stay, but both are fabulous options for luxury travelers.