Find 4 Star Hotels in Santa Cruz from ￥6,674

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Check availability on Santa Cruz 4 Star Hotels

Tonight
Aug 25 - Aug 26
Tomorrow
Aug 26 - Aug 27
This weekend
Aug 29 - Aug 31
Next weekend
Sep 5 - Sep 7

Compare Santa Cruz 4 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

TRYP by Wyndham Santa Cruz
Outdoor pool, open 9:00 AM to 10:00 PM, free cabanas

TRYP by Wyndham Santa Cruz

4.0 star property
9.2 out of 10, Wonderful, (131)
"Nice stay with good service "
The price is ￥16,016
￥16,016 total
Aug 26 - Aug 27
TRYP by Wyndham Santa Cruz
Camino Real Hotel
Indoor pool, outdoor pool, pool umbrellas

Camino Real Hotel

4.5 star property
8.8 out of 10, Excellent, (396)
"Great Hotel, had a great time ."
The price is ￥20,572
￥20,572 total
Sep 15 - Sep 16
Camino Real Hotel
Hampton by Hilton Santa Cruz/Equipetrol, Bolivia
Lounge

Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

4.5 star property
9.2 out of 10, Wonderful, (248)
"Nice hotel "
The price is ￥13,812
￥13,812 total
Aug 28 - Aug 29
Hampton by Hilton Santa Cruz/Equipetrol, Bolivia
Hotel Maywa
Junior Single Room | 1 bedroom, Egyptian cotton sheets, premium bedding, in-room safe

Hotel Maywa

4.0 star property
9.2 out of 10, Wonderful, (10)
"Es mi segunda vez hospedandome en el hotel, la atención excelente, desayuno muy rico y variado, la habitacion tiene cama muy comoda y una excelente limpieza"
The price is ￥6,674
￥6,674 total
Aug 26 - Aug 27
Hotel Maywa
Swissôtel Santa Cruz De La Sierra
Massages

Swissôtel Santa Cruz De La Sierra

4.5 star property
9.2 out of 10, Wonderful, (77)
"Beautiful hotel"
The price is ￥19,176
￥19,176 total
Aug 29 - Aug 30
Swissôtel Santa Cruz De La Sierra
Buganvillas Hotel Suites & Spa
Aerial view

Buganvillas Hotel Suites & Spa

4.0 star property
7.4 out of 10, Good, (92)
"Gammelt og veldig slitt og skittent. Det var et fint hotell for 20 år siden. Men ikke vedlikeholdt. "
Buganvillas Hotel Suites & Spa
Royal Lodge Hotel
Front of property - evening/night

Royal Lodge Hotel

4.5 star property
6.4 out of 10, (29)
"Esta cerrado, ya no deberia dejar reservar, se nota q tiene tiempo fuera de servicio."
Royal Lodge Hotel
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Explore similar 5-star hotels

Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Santa Cruz.
Marriott Santa Cruz de la Sierra Hotel

Marriott Santa Cruz de la Sierra Hotel

4to Anillo Entre Radial 23, At Calle Las Ramblas, Santa Cruz, Santa Cruz
The price is ￥15,164 per night from Aug 30 to Aug 31
￥15,164
￥15,164 total
Aug 30 - Aug 31
9/10 Wonderful! (191 reviews)
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Santa Cruz

Tropical energy pulses through Plaza 24 de Septiembre, where locals gather under palm trees and the Metropolitan Cathedral's twin towers stand watch. Biocentro Güembé offers rainforest trails with butterfly gardens, while the massive Ventura Mall provides air-conditioned shopping when afternoon temperatures climb.

See all hotels in Santa Cruz
San Lorenzo Cathedral showing a garden

Top Santa Cruz Hotel Reviews

Hotel Maywa

Hotel Maywa

10/10 Excellent
"The hotel was conveniently located within walking distance to shoos, restaurants and attractions. The rooms were clean, spacious and comfortable. The hotel staff were friendly and helped our large group arrange transportation to and from the airport. "
Walter 1-night trip
Posted 2 months ago
Hotel Maywa

Frequently asked questions

What are the best 4-star hotels in Santa Cruz?
If you're seeking luxury comfort and loads of amenities during your Santa Cruz retreat, consider TRYP by Wyndham Santa Cruz. This 4-star hotel offers a spa tub and a terrace. Hampton by Hilton Santa Cruz/Equipetrol, Bolivia also gets stellar reviews from Expedia guests. Concierge services and a garden are among its conveniences.
How much does it cost to stay in a 4-star hotel in Santa Cruz?
Expedia can help you easily locate the perfect 4-star hotel for your vacation in Santa Cruz. Use our filter tool to tailor your search by things like price, conveniences and star rating and get access to terrific deals in a few clicks.

  • Search for the lowest price from ￥15,164

What's the difference between 5-star and 4-star hotels in Santa Cruz?
If you choose to spend your vacation at a 4-star hotel in Santa Cruz, you'll typically find plenty of conveniences to ensure you're comfortable, such as a restaurant, gym and pool. You can enjoy top-quality service and deluxe accommodations. Choose a 5-star hotel and you'll get a few extra perks — think concierge assistance, on-site spas and opulent turndown services. You're likely to get more amenities and premium services at a 5-star stay, but both are fabulous options for luxury travelers.