Find 4 Star Hotels in Santa Cruz from ￥6,851

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Check availability on Santa Cruz 4 Star Hotels

Compare Santa Cruz 4 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

Camino Real Hotel
Indoor pool, outdoor pool, pool umbrellas

Camino Real Hotel

4.5 star property
8.8 out of 10, Excellent, (396)
"Great Hotel, had a great time ."
The price is ￥20,684
￥20,684 total
Sep 1 - Sep 2
Camino Real Hotel
Hampton by Hilton Santa Cruz/Equipetrol, Bolivia
Lounge

Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

4.5 star property
9.2 out of 10, Wonderful, (247)
"Location, surrounding, quietness, good service "
The price is ￥11,110
￥11,110 total
Aug 15 - Aug 16
Hampton by Hilton Santa Cruz/Equipetrol, Bolivia
TRYP by Wyndham Santa Cruz
Outdoor pool, open 9:00 AM to 10:00 PM, free cabanas

TRYP by Wyndham Santa Cruz

4.0 star property
9.2 out of 10, Wonderful, (130)
"Nice stay with good service "
The price is ￥16,104
￥16,104 total
Aug 13 - Aug 14
TRYP by Wyndham Santa Cruz
Hotel Maywa
Junior Single Room | 1 bedroom, Egyptian cotton sheets, premium bedding, in-room safe

Hotel Maywa

4.0 star property
9.2 out of 10, Wonderful, (10)
"Es mi segunda vez hospedandome en el hotel, la atención excelente, desayuno muy rico y variado, la habitacion tiene cama muy comoda y una excelente limpieza"
The price is ￥6,851
￥6,851 total
Aug 20 - Aug 21
Hotel Maywa
Swissôtel Santa Cruz De La Sierra
Massages

Swissôtel Santa Cruz De La Sierra

4.5 star property
9.2 out of 10, Wonderful, (77)
"Beautiful hotel"
The price is ￥12,854
￥12,854 total
Aug 28 - Aug 29
Swissôtel Santa Cruz De La Sierra
Buganvillas Hotel Suites & Spa
Aerial view

Buganvillas Hotel Suites & Spa

4.0 star property
7.4 out of 10, Good, (92)
"El Hotel es bonito, pero tienen su mobiliario bastante descuidado en la piscina y el servicio no es nada bueno. Tardan mucho para cosas simples y la piscina no está temperada como solía estar, han desmejorado mucho"
Buganvillas Hotel Suites & Spa
Royal Lodge Hotel
Front of property - evening/night

Royal Lodge Hotel

4.5 star property
6.4 out of 10, (29)
"Esta cerrado, ya no deberia dejar reservar, se nota q tiene tiempo fuera de servicio."
Royal Lodge Hotel
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Explore similar 5-star hotels

Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Santa Cruz.
Marriott Santa Cruz de la Sierra Hotel

Marriott Santa Cruz de la Sierra Hotel

4to Anillo Entre Radial 23, At Calle Las Ramblas, Santa Cruz, Santa Cruz
The price is ￥17,611 per night from Aug 22 to Aug 23
￥17,611
￥17,611 total
Aug 22 - Aug 23
9/10 Wonderful! (191 reviews)
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Santa Cruz

Experience Bolivia as the locals see it in the country’s busiest city, where the museums, public squares and churches give you a glimpse into their everyday lives.

See all hotels in Santa Cruz
San Lorenzo Cathedral showing a garden

Top Santa Cruz Hotel Reviews

Hotel Maywa

Hotel Maywa

10/10 Excellent
"The hotel was conveniently located within walking distance to shoos, restaurants and attractions. The rooms were clean, spacious and comfortable. The hotel staff were friendly and helped our large group arrange transportation to and from the airport. "
Walter 1-night trip
Posted 1 month ago
Hotel Maywa

Frequently asked questions

What are the best 4-star hotels in Santa Cruz?
If you're seeking luxury comfort and loads of amenities during your Santa Cruz retreat, consider TRYP by Wyndham Santa Cruz. This 4-star hotel offers a spa tub and a terrace. Hampton by Hilton Santa Cruz/Equipetrol, Bolivia also gets stellar reviews from Expedia guests. Concierge services and a garden are among its conveniences.
How much does it cost to stay in a 4-star hotel in Santa Cruz?
Expedia can help you easily locate the perfect 4-star hotel for your vacation in Santa Cruz. Use our filter tool to tailor your search by things like price, conveniences and star rating and get access to terrific deals in a few clicks.

  • Search for the lowest price from ￥15,513

What's the difference between 5-star and 4-star hotels in Santa Cruz?
If you choose to spend your vacation at a 4-star hotel in Santa Cruz, you'll typically find plenty of conveniences to ensure you're comfortable, such as a restaurant, gym and pool. You can enjoy top-quality service and deluxe accommodations. Choose a 5-star hotel and you'll get a few extra perks — think concierge assistance, on-site spas and opulent turndown services. You're likely to get more amenities and premium services at a 5-star stay, but both are fabulous options for luxury travelers.