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Our top choices for Santa Cruz hotels

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
3.5 star property
Santa Cruz
9.0 out of 10, Wonderful, (351)
"Great spacious property with nice pool!"
United States
Douglas
The price is ¥20,554
¥20,554 total
Jan 30 - Jan 31
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

Marriott Santa Cruz de la Sierra Hotel

Marriott Santa Cruz de la Sierra Hotel
5.0 star property
Santa Cruz
9.0 out of 10, Wonderful, (213)
"Great hotel, food and location albeit a little expensive "
United States
Reinaldo
The price is ¥17,447
¥17,447 total
Jan 16 - Jan 17
Marriott Santa Cruz de la Sierra Hotel

Ibis Santa Cruz DE LA Sierra

Ibis Santa Cruz DE LA Sierra
3.0 star property
Santa Cruz
9.4 out of 10, Exceptional, (80)
"Amazing breakfast "
United States
Sergio
The price is ¥6,727
¥6,727 total
Jan 10 - Jan 11
Ibis Santa Cruz DE LA Sierra

Sun Hotel

Sun Hotel
3.5 star property
Santa Cruz
8.2 out of 10, Very Good, (333)
"Staff spoke English. Airport pickup beat any US hotel. Rooms nice. Restaurant was ok"
United States
Peter
The price is ¥14,047
¥14,047 total
Jan 10 - Jan 11
Sun Hotel

Camino Real Hotel

Camino Real Hotel
4.5 star property
Santa Cruz
8.8 out of 10, Excellent, (410)
"The parrots. Unique"
United States
Juan P
The price is ¥28,269
¥28,269 total
Jan 10 - Jan 11
Camino Real Hotel

HOTEL OSHO

HOTEL OSHO
3.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (38)
"Hot tub worked well and room was very comfortable! 24 hr market across the street came in handy. The best hotel I've stayed at in Bolivia!"
United States
Robert
The price is ¥6,601
¥6,601 total
Jan 10 - Jan 11
HOTEL OSHO

Novotel Santa Cruz De La Sierra

Novotel Santa Cruz De La Sierra
5.0 star property
Santa Cruz
9.2 out of 10, Wonderful, (104)
"Luxurious hotel,very chic and beautiful."
United States
Cristhian
The price is ¥19,613
¥19,613 total
Feb 3 - Feb 4
Novotel Santa Cruz De La Sierra

Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

Hampton by Hilton Santa Cruz/Equipetrol, Bolivia
4.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (259)
"Nice hotel "
United States
Narciso Lorenzo
The price is ¥11,548
¥11,548 total
Feb 1 - Feb 2
Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

Apart Hotel Premium Suites Santa Cruz

Apart Hotel Premium Suites Santa Cruz
3.5 star property
Santa Cruz
8.6 out of 10, Excellent, (96)
"Yes, staff were very friendly "
United States
veronica
Apart Hotel Premium Suites Santa Cruz

Hotel Cortez

Hotel Cortez
3.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (124)
"The staff and property are second to none! "
United States
Cynthia
The price is ¥20,379
¥20,379 total
Jan 10 - Jan 11
Hotel Cortez

Premium Suites Deluxe Aparthotel Equipetrol

Premium Suites Deluxe Aparthotel Equipetrol
3.5 star property
Santa Cruz
9.0 out of 10, Wonderful, (82)
"Good price, great hotel!"
United States
James
The price is ¥6,111
¥6,111 total
Jan 10 - Jan 11
Premium Suites Deluxe Aparthotel Equipetrol

Chairú Eco Hotel

Chairú Eco Hotel
3.5 star property
Santa Cruz
9.6 out of 10, Exceptional, (49)
"Nice property. Would definitely stay there again and again. Only negative was on our last night there was a really noisy party next door that lasted until 2am. "
United States
Andrew
Chairú Eco Hotel

Swissôtel Santa Cruz De La Sierra

Swissôtel Santa Cruz De La Sierra
4.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (82)
"Beautiful hotel"
Australia
Joanna
The price is ¥19,713
¥19,713 total
Jan 23 - Jan 24
Swissôtel Santa Cruz De La Sierra

TRYP by Wyndham Santa Cruz

TRYP by Wyndham Santa Cruz
4.0 star property
Santa Cruz
9.2 out of 10, Wonderful, (149)
"The hotel is well located, convenient for restaurants and shopping, and very quiet. We stayed in a 2-bedroom suite, very well appointed and comfortable. Love the design of the corridor! Staff are friendly and helpful. A bar at the dining area where breakfast is would be great."
United States
Vivian
The price is ¥15,513
¥15,513 total
Jan 10 - Jan 11
TRYP by Wyndham Santa Cruz

Delfines Collection Hotel By Mercure

Delfines Collection Hotel By Mercure
3.5 star property
Santa Cruz
9.0 out of 10, Wonderful, (74)
"Excellent place to stay!"
United States
Luisa
The price is ¥6,642
¥6,642 total
Jan 23 - Jan 24
Delfines Collection Hotel By Mercure

Lido Hotel

Lido Hotel
3.0 star property
Santa Cruz
9.0 out of 10, Wonderful, (31)
"Very helpful and nice staff. Quiet location. near the central plaza. Great value "
United Kingdom
David
The price is ¥5,546
¥5,546 total
Jan 10 - Jan 11
Lido Hotel

Alfonsina Hotel Boutique by Inboccaluppo

Alfonsina Hotel Boutique by Inboccaluppo
3.5 star property
Santa Cruz
9.4 out of 10, Exceptional, (40)
"Love it. Will stay again!!"
United States
Juan
The price is ¥20,978
¥20,978 total
Jan 10 - Jan 11
Alfonsina Hotel Boutique by Inboccaluppo

Hotel LP Santa Cruz Centro

Hotel LP Santa Cruz Centro
3.0 star property
Santa Cruz
8.0 out of 10, Very Good, (282)
"Clean, friendly staff"
United States
Giovanna
Hotel LP Santa Cruz Centro

Hotel LP Equipetrol

Hotel LP Equipetrol
3.5 star property
Santa Cruz
8.2 out of 10, Very Good, (201)
"Nice place to stay"
United States
Ricardo
The price is ¥7,333
¥7,333 total
Jan 30 - Jan 31
Hotel LP Equipetrol

Equipetrol Suites Apart Hotel

Equipetrol Suites Apart Hotel
2.5 star property
Santa Cruz
8.8 out of 10, Excellent, (9)
"Perfect hotel"
Turkey
Yener
Equipetrol Suites Apart Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Top Santa Cruz Hotel Reviews

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Frequently asked questions

How much do hotels in Santa Cruz cost?
The season and factors like school holidays, Christmas and Easter can influence the price of a hotel in Santa Cruz. You can find cheap options from ¥5,546 in a few different ways on Expedia. First, key in the dates you'd like to go on vacation, then use the filters such as property type and amenities to refine your search. You can also sort by price, so the most inexpensive options appear at the top.
When is the best time to go to Santa Cruz?
If you're thinking of visiting in summer, reserve your Santa Cruz hotel between December and February. Temperatures during the summer here range from 22ºC to 31ºC. Santa Cruz has an oceanic climate, so pack appropriately.
Are there any luxury hotels in Santa Cruz?
Expedia has got some terrific stays for an indulgent escape in Santa Cruz, Santa Cruz, such as Hampton by Hilton Santa Cruz/Equipetrol, Bolivia. Check in and make use of amenities like concierge services, a garden and complimentary breakfast. Alternatively, treat yourself at Radisson Hotel Santa Cruz.
What are the top all-inclusive hotels in Santa Cruz?
If you're looking for a relaxed and worry-free escape, throw your bags down at Prince Hotel. Generally including your drinks, food and some recreational activities in the flat upfront rate, it's one of the best options for an all-inclusive retreat in Santa Cruz.
How can I find cheap hotels in Santa Cruz?
Discover inexpensive hotels with minimal effort by making use of our filter tool. Choose the "Price per night" box to view low-cost options in Santa Cruz. Another way is to take a look at our cheap hotels in Santa Cruz page. The lowest price available starts from ¥5,546 per night.
What are the best hotels in Santa Cruz for families?
Cosmopolitano Hotel Boutique is one of the top-rated hotels for families, located in Santa Cruz, Santa Cruz. Book here and take advantage of conveniences such as complimentary breakfast and a cafe. Hampton by Hilton Santa Cruz/Equipetrol, Bolivia is another favorite where kiddos are welcome. For more hotel options, fine-tune your search results by selecting "Family friendly" under the "Traveler experience" filter heading.
Why should I book my Santa Cruz hotel with Expedia?
Reserve a Santa Cruz hotel with Expedia for choice, price and ease. Also, our One Key™ rewards program lets you earn OneKeyCash™* on eligible flights, car rentals, hotels, vacation rentals and more. Plus, we offer flexibility in case your plans change, and if you have any questions or require assistance, our online Help Center is always available.*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.