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Compare 214 hotels in Santa Cruz with room rates, reviews, and availability. Most hotels are fully refundable.

Ibis Santa Cruz DE LA Sierra
3.0 star property
9.8 out of 10, Exceptional, (26)
"I had a great stay at this hotel. It has a good location, within reasonable walking distance to the old town or the restaurant area, though Uber is very easy and cheap. The hotel is good, modern and clean . The ambience is very quiet , I would have liked a more interesting and lively vibe. The room was very spacious and comfortable. The only downside was that my room did not have a mini-fridge. The front desk staff was very helpful and kind. "
The price is ¥10,137
per night
May 30 - May 31
Ibis Santa Cruz DE LA Sierra
Chairú Eco Hotel
3.5 star property
9.8 out of 10, Exceptional, (11)
"Very happy to be at this Beautiful hotel personnel was excellent and willing to help you with your needs"
The price is ¥7,830
per night
May 21 - May 22
Chairú Eco Hotel
El Pueblito Hotel Boutique
3.0 star property
9.8 out of 10, Exceptional, (16)
"El Pueblito is a unique property in Samaipata. Views of the city below are great. All rooms are decorated with different themes related to the buildings of the little town. In the lush gardens peacocks and horses roam freely. The food was just OK. Service was attentive. However, because of its location on the top of the hill, your need a car to move around. After rain, you even might need a 4x4 to reach the hotel. Anyway, I still think is the best place to stay in Samaipata."
The price is ¥13,610
per night
May 16 - May 17
El Pueblito Hotel Boutique
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TRYP by Wyndham Santa Cruz
4.0 star property
9.4 out of 10, Exceptional, (76)
"We didn’t arrive until 5:00am and they kept our room available for our late arrival. Staff was A ! Highly recommend and will stay there again."
The price is ¥9,887
per night
Jun 1 - Jun 2
TRYP by Wyndham Santa Cruz
Hampton by Hilton Santa Cruz/Equipetrol, Bolivia
4.5 star property
9.2 out of 10, Wonderful, (193)
"It’s an awesome place. Location couldn’t be better. Restaurants, cafes, shopping all within walking distance. Neighborhoods to walk around a get to know. Easy transportation to historic downtown and very reasonable cost. "
The price is ¥13,951
per night
May 21 - May 22
Hampton by Hilton Santa Cruz/Equipetrol, Bolivia
Premium Suites Deluxe Aparthotel Equipetrol
3.5 star property
9.2 out of 10, Wonderful, (60)
"Great service. Very nice and accommodating staffs "
The price is ¥8,327
per night
May 16 - May 17
Premium Suites Deluxe Aparthotel Equipetrol
Novotel Santa Cruz De La Sierra
5.0 star property
9.2 out of 10, Wonderful, (63)
"Nice hotel, clean, modern and very comfortable. Nice view. The best option for a solo traveler or business trip in Santa Cruz"
The price is ¥11,147
per night
Jun 4 - Jun 5
Novotel Santa Cruz De La Sierra
Fiori Apartment
3.5 star property
9.2 out of 10, Wonderful, (70)
"Really nice and confirtable"
The price is ¥5,612
per night
May 20 - May 21
Fiori Apartment
Hotel Cortez
3.5 star property
9.0 out of 10, Wonderful, (72)
"Great hotel. The service was outstanding. The room was very clean and nice. It looks just like the pictures. The included breakfast was delicious"
The price is ¥17,286
per night
May 17 - May 18
Hotel Cortez
Swissôtel Santa Cruz De La Sierra
4.5 star property
9.0 out of 10, Wonderful, (41)
"Good"
The price is ¥14,732
per night
May 20 - May 21
Swissôtel Santa Cruz De La Sierra
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
3.5 star property
8.8 out of 10, Excellent, (283)
"Hotel is great. Service is better. Rooms by the pool, which should be the centerpiece of the property, are a bit dated. Bed was just ok. Comfortable enough but not great. "
The price is ¥19,529
per night
May 27 - May 28
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
Marriott Santa Cruz de la Sierra Hotel
5.0 star property
8.8 out of 10, Excellent, (147)
"Clean comfortable room and beds. Nice fitness center. Small pool and hot tub could be hotter. Munimal vegan options at restaurant but lots of other places nearby. "
The price is ¥16,019
per night
May 31 - Jun 1
Marriott Santa Cruz de la Sierra Hotel
Camino Real Hotel
4.5 star property
8.8 out of 10, Excellent, (327)
"Excelente hotel, muy confortable. Lo único malo es que no se puede desayunar con la ropa que saldrás al trabajo, hay mucho olor a comida en el restaurante y se queda en la ropa."
The price is ¥19,997
per night
May 19 - May 20
Camino Real Hotel
Apart Hotel Buen Retiro
2.5 star property
8.8 out of 10, Excellent, (48)
"Great"
The price is ¥6,249
per night
May 26 - May 27
Apart Hotel Buen Retiro
HOTEL OSHO
3.5 star property
8.6 out of 10, Excellent, (18)
"I like his service "
The price is ¥10,476
per night
May 27 - May 28
HOTEL OSHO
Apart Hotel Toborochi
3.0 star property
8.6 out of 10, Excellent, (57)
"Great pool and rooms, bad service and staff "
The price is ¥8,917
per night
May 19 - May 20
Apart Hotel Toborochi
Delfines Collection Hotel By Mercure
3.5 star property
8.4 out of 10, Very Good, (19)
"Buena ubicación. Personal amable. Lugar tranquilo. Habitaciones confortables. "
The price is ¥6,031
per night
May 19 - May 20
Delfines Collection Hotel By Mercure
Hotel LP Equipetrol
3.5 star property
8.2 out of 10, Very Good, (185)
"The property is good. My only problem was the wifi which in my room was very poor and in other areas very slow."
The price is ¥9,664
per night
May 26 - May 27
Hotel LP Equipetrol
Sun Hotel
3.5 star property
8.2 out of 10, Very Good, (243)
"This property is great if you need proximity to the airport. I arrived on a late evening flight and was flying back out in the morning. The shuttle service was very accommodating, waiting for me while I got my tourist visa. "
The price is ¥18,982
per night
May 20 - May 21
Sun Hotel
Senses Boutique Hotel
3.5 star property
8.0 out of 10, Very Good, (287)
"Very large and confortable rooms in central location. Breakfast could be better but staff is very friendly and helpful "
Senses Boutique Hotel
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Santa Cruz hotels information

Number of reviews
2,233
Accommodation
214 hotels
Lowest Price
¥5,612
Highest Price
¥19,997

Frequently asked questions

How much do hotels in Santa Cruz cost?
The season and factors like school holidays, Christmas and Easter can affect the price of a hotel in Santa Cruz. You can find cheap options from ¥5,612 in a few different ways on Expedia. First, key in the dates you’d like to go on vacation, then use the filters such as property type and amenities to refine your search. You can also sort by price, so the most affordable options appear first.
When is the best time to go to Santa Cruz?
The answer depends on what you want to get out of your Santa Cruz vacation. If you want to visit in summer, which is between December and February, expect average temperatures of between 22ºC and 31ºC. Santa Cruz has a tropical savanna climate, so keep that in mind when packing.
Are there any luxury hotels in Santa Cruz?
We’ve got some superb stays for a lavish vacation in Santa Cruz, Santa Cruz, including Hampton by Hilton Santa Cruz/Equipetrol, Bolivia. Book a room and make use of amenities like concierge services, complimentary breakfast and a garden. Or pamper yourself at Radisson Hotel Santa Cruz.
What are the top all-inclusive hotels in Santa Cruz?
If you’re searching for a relaxed and worry-free escape, settle in at Prince Hotel. Typically including your food, meals, snacks and some recreational activities in the flat upfront price, it’s among the best picks for an all-inclusive stay in Santa Cruz.
How can I find cheap hotels in Santa Cruz?
An excellent place to begin your search is with our “Price per night” filter. At the moment, the cheapest hotels start at ¥5,612 per night. Other ways to snap up a pocket-friendly Santa Cruz escape are by booking early and being flexible with travel dates. For more great deals, go to our cheap hotels in Santa Cruz page.
What are the best hotels in Santa Cruz for families?
Cosmopolitano Hotel Boutique is one of the best hotels for families, located in Santa Cruz, Santa Cruz. Stay here and take advantage of conveniences such as complimentary breakfast and a swimming pool. Hampton by Hilton Santa Cruz/Equipetrol, Bolivia is another favorite escape where little ones are welcome. For more hotel options, narrow your search results by clicking on “Family friendly” under the “Traveler experience” filter heading.
What are the top beach hotels in Santa Cruz?
Book one of Expedia’s hotels with sea views in Santa Cruz and spend your break having a blast by the water. De-stress in top-notch accommodations such as Los Cedros Resort & Convention Center, which offers amenities like a swimming pool and a deep soaking bathtub.
Why should I book my Santa Cruz hotel with Expedia?
The best prices on Santa Cruz hotels are just the start of the reasons to book your stay with Expedia. Become an Expedia Rewards member for free today and earn points with every booking, along with membership perks to sweeten the deal. How does savings worth 10% or more on select hotels sound? Plus, most of our hotels offer free cancellation, so you can reserve the getaway of your dreams without having to worry about your plans changing.

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