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Our top choices for Santa Cruz hotels

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
3.5 star property
Santa Cruz
9.0 out of 10, Wonderful, (362 reviews)
"Welcoming clean rooms, friendly staff, continental breakfast with natural drinks "
United States
Victor
The price is ¥21,031
¥21,031 total
Mar 14 - Mar 15
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

Marriott Santa Cruz de la Sierra Hotel

Marriott Santa Cruz de la Sierra Hotel
5.0 star property
Santa Cruz
9.0 out of 10, Wonderful, (215 reviews)
"Great hotel, food and location albeit a little expensive "
United States
Reinaldo
The price is ¥16,431
¥16,431 total
Mar 27 - Mar 28
Marriott Santa Cruz de la Sierra Hotel

Ibis Santa Cruz DE LA Sierra

Ibis Santa Cruz DE LA Sierra
3.0 star property
Santa Cruz
9.6 out of 10, Exceptional, (90 reviews)
"Amazing breakfast "
United States
Sergio
The price is ¥7,641
¥7,641 total
Feb 26 - Feb 27
Ibis Santa Cruz DE LA Sierra

Sun Hotel

Sun Hotel
3.5 star property
Santa Cruz
8.2 out of 10, Very Good, (346 reviews)
"Awesome place "
Canada
John
The price is ¥15,031
¥15,031 total
Feb 28 - Mar 1
Sun Hotel

Camino Real Hotel

Camino Real Hotel
4.5 star property
Santa Cruz
9.0 out of 10, Wonderful, (420 reviews)
"Rooms were very clean and service was excellent "
United States
JESUS
The price is ¥19,511
¥19,511 total
Mar 15 - Mar 16
Camino Real Hotel

Premium Suites Deluxe Aparthotel Equipetrol

Premium Suites Deluxe Aparthotel Equipetrol
3.5 star property
Santa Cruz
9.0 out of 10, Wonderful, (86 reviews)
"Good price, great hotel!"
United States
James
The price is ¥6,031
¥6,031 total
Feb 25 - Feb 26
Premium Suites Deluxe Aparthotel Equipetrol

Novotel Santa Cruz De La Sierra

Novotel Santa Cruz De La Sierra
5.0 star property
Santa Cruz
9.2 out of 10, Wonderful, (107 reviews)
"Luxurious hotel,very chic and beautiful."
United States
Cristhian
The price is ¥16,237
¥16,237 total
Mar 14 - Mar 15
Novotel Santa Cruz De La Sierra

HOTEL OSHO

HOTEL OSHO
3.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (43 reviews)
"Room was great and staff were very accommodating!"
Canada
David
The price is ¥7,750
¥7,750 total
Feb 25 - Feb 26
HOTEL OSHO

Apart Hotel Premium Suites Santa Cruz

Apart Hotel Premium Suites Santa Cruz
3.5 star property
Santa Cruz
8.6 out of 10, Excellent, (98 reviews)
"Yes, staff were very friendly "
United States
veronica
Apart Hotel Premium Suites Santa Cruz

Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

Hampton by Hilton Santa Cruz/Equipetrol, Bolivia
4.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (263 reviews)
"Nice hotel "
United States
Narciso Lorenzo
The price is ¥11,382
¥11,382 total
Mar 1 - Mar 2
Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

Chairú Eco Hotel

Chairú Eco Hotel
3.5 star property
Santa Cruz
9.6 out of 10, Exceptional, (56 reviews)
"Staff was very courteous. They went above & beyond. Location was great!"
United States
America
Chairú Eco Hotel

Swissôtel Santa Cruz De La Sierra

Swissôtel Santa Cruz De La Sierra
4.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (84 reviews)
"Beautiful hotel"
Australia
Joanna
The price is ¥19,454
¥19,454 total
Mar 11 - Mar 12
Swissôtel Santa Cruz De La Sierra

Hotel Cortez

Hotel Cortez
3.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (125 reviews)
"The staff and property are second to none! "
United States
Cynthia
The price is ¥18,928
¥18,928 total
Mar 14 - Mar 15
Hotel Cortez

TRYP by Wyndham Santa Cruz

TRYP by Wyndham Santa Cruz
4.0 star property
Santa Cruz
9.2 out of 10, Wonderful, (152 reviews)
"Yes! Room was spotless. The staff are very patient and professional. "
United States
Pluetina
The price is ¥15,309
¥15,309 total
Feb 25 - Feb 26
TRYP by Wyndham Santa Cruz

Equipetrol Suites Apart Hotel

Equipetrol Suites Apart Hotel
2.5 star property
Santa Cruz
9.0 out of 10, Wonderful, (12 reviews)
"Perfect hotel"
Turkey
Yener
The price is ¥8,472
¥8,472 total
Mar 25 - Mar 26
Equipetrol Suites Apart Hotel

Hotel LP Equipetrol

Hotel LP Equipetrol
3.5 star property
Santa Cruz
8.2 out of 10, Very Good, (202 reviews)
"Nice place to stay"
United States
Ricardo
Hotel LP Equipetrol

Lido Hotel

Lido Hotel
3.0 star property
Santa Cruz
9.0 out of 10, Wonderful, (33 reviews)
"Very helpful and nice staff. Quiet location. near the central plaza. Great value "
United Kingdom
David
The price is ¥7,106
¥7,106 total
Mar 5 - Mar 6
Lido Hotel

Delfines Collection Hotel By Mercure

Delfines Collection Hotel By Mercure
3.5 star property
Santa Cruz
9.0 out of 10, Wonderful, (81 reviews)
"Clean, well maintained and good customer service."
United States
Johnny
The price is ¥5,564
¥5,564 total
Feb 28 - Mar 1
Delfines Collection Hotel By Mercure

Hotel Las Américas

Hotel Las Américas
3.0 star property
Santa Cruz
8.0 out of 10, Very Good, (2 reviews)
"O chuveiro foi impossível tomar um.banho de qualidade "
Brazil
Jean
The price is ¥5,943
¥5,943 total
Feb 25 - Feb 26
Hotel Las Américas

Hotel LP Santa Cruz Centro

Hotel LP Santa Cruz Centro
3.0 star property
Santa Cruz
8.0 out of 10, Very Good, (284 reviews)
"Awesome hotel "
Canada
John
Hotel LP Santa Cruz Centro
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Top Santa Cruz Hotel Reviews

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Frequently asked questions

How much do hotels in Santa Cruz cost?
The season and factors like school holidays, Christmas and Easter can influence the price of a hotel in Santa Cruz. You can find cheap options from ¥5,564 in a few different ways on Expedia. First, key in the dates you'd like to go on vacation, then use the filters such as property type and amenities to refine your search. You can also sort by price, so the most inexpensive options appear at the top.
When is the best time to go to Santa Cruz?
If you're thinking of visiting in summer, reserve your Santa Cruz hotel between December and February. Temperatures during the summer here range from 22ºC to 31ºC. Santa Cruz has an oceanic climate, so pack appropriately.
Are there any luxury hotels in Santa Cruz?
Expedia has got some terrific stays for an indulgent escape in Santa Cruz, Santa Cruz, such as Hampton by Hilton Santa Cruz/Equipetrol, Bolivia. Check in and make use of amenities like concierge services, a garden and complimentary breakfast. Alternatively, treat yourself at Radisson Hotel Santa Cruz.
What are the top all-inclusive hotels in Santa Cruz?
If you're looking for a relaxed and worry-free escape, throw your bags down at Prince Hotel. Generally including your drinks, food and some recreational activities in the flat upfront rate, it's one of the best options for an all-inclusive retreat in Santa Cruz.
How can I find cheap hotels in Santa Cruz?
Discover inexpensive hotels with minimal effort by making use of our filter tool. Choose the "Price per night" box to view low-cost options in Santa Cruz. Another way is to take a look at our cheap hotels in Santa Cruz page. The lowest price available starts from ¥5,564 per night.
What are the best hotels in Santa Cruz for families?
Cosmopolitano Hotel Boutique is one of the top-rated hotels for families, located in Santa Cruz, Santa Cruz. Book here and take advantage of conveniences such as complimentary breakfast and a cafe. Hampton by Hilton Santa Cruz/Equipetrol, Bolivia is another favorite where kiddos are welcome. For more hotel options, fine-tune your search results by selecting "Family friendly" under the "Traveler experience" filter heading.
Why should I book my Santa Cruz hotel with Expedia?
Reserve a Santa Cruz hotel with Expedia for choice, price and ease. Also, our One Key™ rewards program lets you earn OneKeyCash™* on eligible flights, car rentals, hotels, vacation rentals and more. Plus, we offer flexibility in case your plans change, and if you have any questions or require assistance, our online Help Center is always available.*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.