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Our top choices for Santa Cruz hotels

AMERICA APARTMENTS

AMERICA APARTMENTS
3.0 star property
Santa Cruz
10.0 out of 10, Exceptional, (1 review)
"Clean room, great staff "
Canada
Peter
The price is ¥8,785
¥8,785 total
Mar 17 - Mar 18
AMERICA APARTMENTS

Novotel Santa Cruz De La Sierra

Novotel Santa Cruz De La Sierra
5.0 star property
Santa Cruz
9.2 out of 10, Wonderful, (109 reviews)
"Luxurious hotel,very chic and beautiful."
United States
Cristhian
The price is ¥16,772
¥16,772 total
Apr 6 - Apr 7
Novotel Santa Cruz De La Sierra

Sun Hotel

Sun Hotel
3.5 star property
Santa Cruz
8.2 out of 10, Very Good, (351 reviews)
"Awesome place "
Canada
John
The price is ¥15,526
¥15,526 total
Mar 22 - Mar 23
Sun Hotel

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
3.5 star property
Santa Cruz
9.0 out of 10, Wonderful, (364 reviews)
"Very nice and cozy"
United States
Dario
The price is ¥21,647
¥21,647 total
Mar 29 - Mar 30
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

Hampton by Hilton Santa Cruz/Equipetrol, Bolivia
4.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (264 reviews)
"The room was clean, breakfast was standard for South America and the staff were great. However, the bed was advertised as a queen and it was a double bed. The rolling desk chair on the tile floor is a serious accident waiting to happen. I enjoyed the views from the rooftop buffet. "
Canada
Patrick
The price is ¥11,756
¥11,756 total
Mar 20 - Mar 21
Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

Marriott Santa Cruz de la Sierra Hotel

Marriott Santa Cruz de la Sierra Hotel
5.0 star property
Santa Cruz
9.0 out of 10, Wonderful, (219 reviews)
"Great hotel, food and location albeit a little expensive "
United States
Reinaldo
The price is ¥16,971
¥16,971 total
Mar 28 - Mar 29
Marriott Santa Cruz de la Sierra Hotel

Hotel Cortez

Hotel Cortez
3.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (128 reviews)
"Lovely hotel. Great room, location, staff and amenities. "
Norway
Solvei Emily Brekke
The price is ¥14,747
¥14,747 total
Mar 20 - Mar 21
Hotel Cortez

Premium Suites Deluxe Aparthotel Equipetrol

Premium Suites Deluxe Aparthotel Equipetrol
3.5 star property
Santa Cruz
9.0 out of 10, Wonderful, (87 reviews)
"Good price, great hotel!"
United States
James
The price is ¥6,229
¥6,229 total
Mar 17 - Mar 18
Premium Suites Deluxe Aparthotel Equipetrol

Ibis Santa Cruz DE LA Sierra

Ibis Santa Cruz DE LA Sierra
3.0 star property
Santa Cruz
9.6 out of 10, Exceptional, (95 reviews)
"Amazing breakfast "
United States
Sergio
The price is ¥8,769
¥8,769 total
Mar 20 - Mar 21
Ibis Santa Cruz DE LA Sierra

Apart Hotel Premium Suites Santa Cruz

Apart Hotel Premium Suites Santa Cruz
3.5 star property
Santa Cruz
8.6 out of 10, Excellent, (100 reviews)
"Place is clean , safe area , walking distance to shops "
United States
Nataly
The price is ¥4,313
¥4,313 total
Mar 17 - Mar 18
Apart Hotel Premium Suites Santa Cruz

Camino Real Hotel

Camino Real Hotel
4.5 star property
Santa Cruz
9.0 out of 10, Wonderful, (420 reviews)
"Rooms were very clean and service was excellent "
United States
JESUS
The price is ¥19,524
¥19,524 total
Apr 10 - Apr 11
Camino Real Hotel

Hotel G

Hotel G
3.5 star property
Santa Cruz
7.8 out of 10, Good, (105 reviews)
"Excelente Hotel "
Mexico
JACOB
The price is ¥5,730
¥5,730 total
Apr 14 - Apr 15
Hotel G

HOTEL OSHO

HOTEL OSHO
3.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (45 reviews)
"Room was great and staff were very accommodating!"
Canada
David
The price is ¥8,913
¥8,913 total
Mar 17 - Mar 18
HOTEL OSHO

Hotel LP Santa Cruz Centro

Hotel LP Santa Cruz Centro
3.0 star property
Santa Cruz
8.0 out of 10, Very Good, (284 reviews)
"Awesome hotel "
Canada
John
The price is ¥7,103
¥7,902 total
Mar 18 - Mar 19
Hotel LP Santa Cruz Centro

Terranova Suites

Terranova Suites
3.5 star property
Santa Cruz
8.0 out of 10, Very Good, (90 reviews)
"Easy to access"
United States
Dorothy
The price is ¥8,292
¥8,292 total
Mar 17 - Mar 18
Terranova Suites

Hotel LP Equipetrol

Hotel LP Equipetrol
3.5 star property
Santa Cruz
8.2 out of 10, Very Good, (204 reviews)
"Nice place to stay"
United States
Ricardo
The price is ¥5,874
¥6,673 total
Mar 20 - Mar 21
Hotel LP Equipetrol

Hotel Continental Park

Hotel Continental Park
3.0 star property
Santa Cruz
8.8 out of 10, Excellent, (25 reviews)
"This is a great option for accomodations near the center of the city. Perhaps 5 or 6 block walk to the main square. Lots of options for restaurantes. The garage is easily accesible. The pool was great and we took advantage of the sauna. Breakfast was great as well. Good variety of food. Staff at the desk was polite and helpful. "
Canada
Gregory
The price is ¥10,997
¥10,997 total
Mar 17 - Mar 18
Hotel Continental Park

Hotel BY Armonia SCZ

Hotel BY Armonia SCZ
3.0 star property
Santa Cruz
8.4 out of 10, Very Good, (7 reviews)
"Very beautiful grounds. They were very responsive and accommodating. I enjoyed the hotel very much. "
United States
Kaerlig
The price is ¥11,955
¥11,955 total
Mar 17 - Mar 18
Hotel BY Armonia SCZ

Apart Hotel Toborochi

Apart Hotel Toborochi
3.0 star property
Santa Cruz
8.8 out of 10, Excellent, (60 reviews)
"Very comfortable and quiet place and very good location. "
United States
Luis
Apart Hotel Toborochi

TRYP by Wyndham Santa Cruz

TRYP by Wyndham Santa Cruz
4.0 star property
Santa Cruz
9.2 out of 10, Wonderful, (155 reviews)
"Yes! Room was spotless. The staff are very patient and professional. "
United States
Pluetina
The price is ¥15,813
¥15,813 total
Mar 17 - Mar 18
TRYP by Wyndham Santa Cruz
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Vacation Rentals in Santa Cruz

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Where to stay in Santa Cruz

Find the best Santa Cruz areas and neighborhoods for the activities you enjoy most. Learn more about Santa Cruz
Learn more about Santa Cruz

Hamacas

While Hamacas isn't home to many top sights, Santa Cruz Zoo and Ventura Mall are some notable places to visit nearby.

Stay near popular Santa Cruz attractions

Learn more about Santa Cruz

Tropical energy pulses through Plaza 24 de Septiembre, where locals gather under palm trees and the Metropolitan Cathedral's twin towers stand watch. Biocentro Güembé offers rainforest trails with butterfly gardens, while the massive Ventura Mall provides air-conditioned shopping when afternoon temperatures climb.

San Lorenzo Cathedral showing a garden

Top Santa Cruz Hotel Reviews

More cheap stays in Santa Cruz

Frequently asked questions

What's the best place for a stay in Santa Cruz?
Chairú Eco Hotel is a favorite with Expedia customers. This hotel offers 2 restaurants and a bar. Reviews from our site also recommend Ibis Santa Cruz DE LA Sierra and TRYP by Wyndham Santa Cruz as top options for your trip. See all available top hotels, or vacation rentals in Santa Cruz.
What's the top vacation rental that Santa Cruz has to offer?
Casa Vida: Visitors give good reviews to this Santa Cruz vacation home rental, which is located in a rural location and has an outdoor pool, a patio, and a barbecue grill to put you at ease in your new surroundings. It has 3 bedrooms as well as a kitchen with a full-sized fridge, a stovetop, and a microwave, so you can cook with friends or family. Kick off your shoes and enjoy yourself with a private yard and a selection of games. Some other homes for rent in Santa Cruz include Cozy 1-bedroom house in beautiful Santa Cruz de la Sierra with WiFi, AC and Seasonal House. See all vacation rentals in Santa Cruz.
If I need to cancel my hotel reservation in Santa Cruz, will I receive a refund?
Yes! Most hotel reservations are fully refundable as long as you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If your reservation is non-refundable, you might still have the option to cancel and get a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Santa Cruz.
Where can I learn more about changing or cancelling my trip to Santa Cruz?
To find more details about picking new dates or cancelling your trip to Santa Cruz, head over to our customer service page.
What's the best budget-friendly accommodation in Santa Cruz?
Based on our traveler reviews, residencial francia - Hostel is a top choice for a less expensive stay. Other choices for your budget-friendly stay include Urubo Suite - Hostel and Residencial Ikandire II. View all budget hotels in Santa Cruz.
What's the best accommodation for a family trip to Santa Cruz?
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel is a hotel with 2 restaurants and free parking, and it's a top choice on Expedia for families. Other choices for your stay with the kids include Marriott Santa Cruz de la Sierra Hotel and Camino Real Hotel. Attractions like Santa Cruz Zoo and Play Land Amusement Park are also fun for kids of all ages. Find more child-friendly accommodations in Santa Cruz.
What is the top LGBTQ-friendly accommodation in Santa Cruz?
Hampton by Hilton Santa Cruz/Equipetrol, Bolivia is a top LGBTQ-friendly hotel that features free breakfast and free WiFi. Swissôtel Santa Cruz De La Sierra and Radisson Hotel Santa Cruz are other good choices for your trip. See all available hotels listed as LGBTQ-friendly in Santa Cruz.
What's the best pet-friendly hotel in Santa Cruz?
Ibis Santa Cruz DE LA Sierra is a top hotel for people traveling with their pets, and offers a restaurant and free WiFi for its human guests. Other good options for you and your pet's trip include Casa Por Temporadas and Prince Hotel. See more pet-friendly hotel accommodations in Santa Cruz.
Where is the best place to stay close to Plaza 24 de Septiembre?
Adjacent to Plaza 24 de Septiembre, Nomad Hostel is one of the top choices for your stay based on our traveler data, and this property offers a restaurant and a bar. Other good options close by include Senses Centro and Cosmopolitano Hotel Boutique.
What about the best place to stay near Ventura Mall?
One of the top choices for your stay is Camino Real Hotel, located next to Ventura Mall, and this 4-star hotel offers 2 bars and a restaurant. Los Tajibos Hotel And Convention Center and Marriott Santa Cruz de la Sierra Hotel are two other good choices in the immediate area.
What's the best luxury accommodation in Santa Cruz?
Marriott Santa Cruz de la Sierra Hotel is a luxury hotel with a full-service spa and a rooftop terrace, and it's a popular choice for Expedia travelers looking for an elegant place to stay. Camino Real Hotel and Hampton by Hilton Santa Cruz/Equipetrol, Bolivia are other upscale choices for your vacation. Find more luxury hotels in Santa Cruz.
What are some accommodations with pools in Santa Cruz?
Sun Hotel is a top hotel with a children's pool, an outdoor pool, and free buffet breakfast. A couple of other options that offer an onsite pool include Yotau All Suites Hotel and Buganvillas Hotel Suites & Spa. View all hotels with pools in Santa Cruz.
What is the best spa hotel in Santa Cruz?
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel is a top spa hotel featuring a fitness center, a hair salon, and a bar. Enjoy a facial, body scrub, or hydrotherapy at Los Tajibos Club Spa. Other popular spa hotels in Santa Cruz include Marriott Santa Cruz de la Sierra Hotel and Camino Real Hotel. See all spa hotels in Santa Cruz.
What's the best hotel for staying near Viru Viru International Airport (VVI)?
Sun Hotel is a popular 3.5-star hotel featuring free breakfast and a restaurant. It's located a short 1.3 mi (2.1 km) from Viru Viru Intl. Airport.
How is it to stay in Santa Cruz?
Visitors to Santa Cruz are sure to enjoy the shopping. Tourists can also enjoy the city's cafes, zoo, and cathedral. In Santa Cruz, there are 287 hotels and other accommodations to choose from. Find out more about Santa Cruz.
What should I do while I'm visiting Santa Cruz?
Cultural venues include Cine Center, Sacred Art Museum, and Ethno-folkloric Museum. Landmarks like San Lorenzo Cathedral, Plaza 24 de Septiembre, and Blacutt Square might be worth a visit. Natural beauty is on display at Guembe Biocenter, Lomas de Arena Regional Park, and Arenal Park. Check out what more to see and do in Expedia's Santa Cruz guide.
How should I get around Santa Cruz?
To see more of the larger area, ride aboard one of the trains from Santa Cruz de la Sierra Station. If you want to venture out around the area, you may want a rental car in Santa Cruz for your journey.
What's the weather like in Santa Cruz?
The hottest months are usually October and November with an average temp of 79°F, while the coldest months are June and July with an average of 70°F. Average annual precipitation for Santa Cruz is 48 inches.