
Santa Cruz Vacations
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Better together
Save up to ¥45,448 when you book a flight and hotel together*
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Find the Best Santa Cruz Vacation Packages
Santa Cruz Hotel Deals

Ibis Santa Cruz DE LA Sierra
AVENIDA CRISTOBAL DE MENDOZA, Santa Cruz
The price is ¥6,348 per night from Sep 10 to Sep 11
¥6,348
¥6,348 total
Sep 10 - Sep 11
9.4/10 Exceptional! (51 reviews)
"The"
Reviewed on Jul 28, 2025

Marriott Santa Cruz de la Sierra Hotel
4to Anillo Entre Radial 23, At Calle Las Ramblas, Santa Cruz, Santa Cruz
The price is ¥15,164 per night from Sep 6 to Sep 7
¥15,164
¥15,164 total
Sep 6 - Sep 7
9/10 Wonderful! (191 reviews)
"all"
Reviewed on Jun 5, 2025

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
Ave. San Martin, #455, Santa Cruz
The price is ¥19,811 per night from Sep 9 to Sep 10
¥19,811
¥19,811 total
Sep 9 - Sep 10
8.8/10 Excellent! (322 reviews)
"Always an amazing hotel"
Reviewed on Jun 21, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Discover the most popular places to visit in Santa Cruz

Plaza 24 de Septiembre
The heart of Santa Cruz lies in this public square, where locals relax and tourists sightsee in a welcoming, laid-back atmosphere.
Santa Cruz Zoo
Why not visit the native and exotic animals who call Santa Cruz Zoo home during your vacation in Santa Cruz? While in the area, you can find time to visit its shops.
What to do in Santa Cruz

Santa Cruz: Wildlife Sanctuary and Preservation Park Tour
¥12,554
per adult

3D/2N Getaway on the Che Guevara Route in Bolivia
¥134,526
per adult
Frequently asked questions
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.