Santa Cruz Vacations

Book a Hotel + Flight or Car together to unlock savings

    Plan, book, travel with confidence
  • payments icon
    Better together
    Save up to ￥9,995 when you book a flight and hotel together*
  • lob hotels icon
    Find the right fit
    With over 300,000 hotels worldwide, it's easy to create a perfect package
  • lob packages icon
    Rest easy
    Plan, book, and manage your trip all in one place

Santa Cruz Hotel Deals

TRYP by Wyndham Santa Cruz
TRYP by Wyndham Santa Cruz
4 out of 5
Av. San Martin, Calle 9 Este, no. 4, Equipetrol., Santa Cruz
Fully refundableReserve now, pay when you stay
The price is ￥10,384 per night from Apr 27 to Apr 28
￥10,384
per night
Apr 27 - Apr 28
9.2/10 Wonderful! (72 reviews)
"Highly recommend staying at the hotel"

Reviewed on Apr 2, 2024

TRYP by Wyndham Santa Cruz
Marriott Santa Cruz de la Sierra Hotel
Marriott Santa Cruz de la Sierra Hotel
5 out of 5
4to Anillo Entre Radial 23, At Calle Las Ramblas, Santa Cruz, Santa Cruz
Fully refundableReserve now, pay when you stay
The price is ￥17,072 per night from May 17 to May 18
￥17,072
per night
May 17 - May 18
8.8/10 Excellent! (143 reviews)
"Clean comfortable room and beds. Nice fitness center. Small pool and hot tub could be hotter. Munimal vegan options at restaurant but lots of other places nearby."

Reviewed on Apr 17, 2024

Marriott Santa Cruz de la Sierra Hotel
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
3.5 out of 5
Ave. San Martin, #455, Santa Cruz
Fully refundableReserve now, pay when you stay
The price is ￥18,866 per night from May 15 to May 16
￥18,866
per night
May 15 - May 16
8.8/10 Excellent! (279 reviews)
Just ok rooms by pool
"Hotel is great. Service is better. Rooms by the pool, which should be the centerpiece of the property, are a bit dated. Bed was just ok. Comfortable enough but not great."

Reviewed on Apr 17, 2024

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
See all 190 properties in Santa Cruz
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Santa Cruz vacation package cost?
Tailor make your Santa Cruz package from only . Pick from any combination of rental cars, flights and hotels to put together the trip you’ve long been dreaming about. Don’t forget to add on one or two experiences!
How do I get a cheap travel package to Santa Cruz?
Bundle your hotels and flights, toss in extras such as a rental car or activities, and save with a Santa Cruz vacation package. You won’t just enjoy big discounts on your trip — you’ll have plenty of choice within your reach too. When you book through Expedia, you can choose from more than 550 partner airlines and 1,000,000 hotels throughout the world. Your next epic adventure begins right here, right now!
Where should I stay in Santa Cruz?
A trip to Santa Cruz isn’t complete without visiting Plaza 24 de Septiembre, Ventura Mall and Santa Cruz Zoo. Spend your nights near these top sights and make sightseeing a breeze.
What are the top hotels in Santa Cruz?
If this will be your first time in Santa Cruz, reserve a room at Swissôtel Santa Cruz De La Sierra or Novotel Santa Cruz De La Sierra. Both have good amenities and are popular options with many travelers.
How far in advance should I book my Santa Cruz vacation?
Reward yourself with the widest variety at the lowest prices by booking your Santa Cruz adventure nice and early. Airlines tend to publish tickets anywhere up to a year prior to departure, so start your planning as soon as possible. That being said, Expedia is committed to giving you the best bargains around, so it’s always a good time to book your dream vacation!
What does an Expedia Santa Cruz travel package include?
It all depends on what sort of trip you have in mind. Santa Cruz travel deals can include hotels, car rentals and flights. You can mix and match to create the bundle that works for you! You can also add on activities and experiences after you’ve booked to score even bigger discounts.
What should I know before booking a Santa Cruz travel package?
When you book your hotels, flights and car rentals together, you’ll enjoy terrific discounts. Whether you’re organizing a beach escape in a villa or would rather stay in a cozy apartment in the city, Expedia will make it happen for less.
Can I choose my airline with a Santa Cruz Expedia vacation package?
With a vacation package, you’re in charge. Whether you’d like to fly to Santa Cruz in business or coach, simply select from the available airline options. Expedia has access to more than 550 airline partners globally.
If I'm not able to travel, can I cancel my Santa Cruz vacation package?
Yes you can, and we’re here to help. You may be able to cancel and rebook your Santa Cruz vacation package at no cost if you booked in the last 24 hours. However, you may incur a fee from your airline, hotel or car rental company for older bookings. If life gets in the way of your vacation, visit our Customer Service Portal for further information.

Discover the most popular places to visit in Santa Cruz

Image for Plaza 24 de Septiembre

Plaza 24 de Septiembre

4.5/5(26 reviews)

The heart of Santa Cruz lies in this public square, where locals relax and tourists sightsee in a welcoming, laid-back atmosphere.

Plaza 24 de Septiembre
Image for San Lorenzo Cathedral

San Lorenzo Cathedral

4.5/5(15 reviews)

One of the most iconic landmarks in Santa Cruz is the city’s mighty cathedral, which houses a museum displaying important artwork.

San Lorenzo Cathedral
Image for Ventura Mall

Ventura Mall

4.5/5(28 reviews)

During your visit to Santa Cruz, you can find the perfect gifts to bring home at Ventura Mall. Make some time to visit the cathedral while you're in the area.

Ventura Mall

What to do in Santa Cruz

Image for Entrance To Our World

Entrance To Our World

￥1,209
Per adult
Entrance To Our World
Image for Santa Cruz de la Sierra Self Guided Sherlock Murder Mystery Game

Santa Cruz de la Sierra Self Guided Sherlock Murder Mystery Game

￥3,185
Per adult
Santa Cruz de la Sierra Self Guided Sherlock Murder Mystery Game
Image for Plants and Habitats in the Elbow of the Andes

Plants and Habitats in the Elbow of the Andes

￥486,123
Per adult
Plants and Habitats in the Elbow of the Andes
See all activities in Santa Cruz

Other vacations you might like

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.