Santa Cruz Vacations
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- Plan, book, travel with confidence
- Better togetherSave up to ￥45,448 when you book a flight and hotel together*
- Find the right fitWith over 300,000 hotels worldwide, it's easy to create a perfect package
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Find the Best Santa Cruz Vacation Packages
Santa Cruz Hotel Deals
Ibis Santa Cruz DE LA Sierra
AVENIDA CRISTOBAL DE MENDOZA Santa Cruz
The price is ￥8,649 per night from Mar 24 to Mar 25
￥8,649
￥8,649 total
Mar 24 - Mar 25
9.6/10 Exceptional! (92 reviews)
El hotel es limpio, ubicado en zona tranquila, el personal es excepcionalmente amable, accesible y respetuoso! Fuimos en 3 ocasiones y volveríamos sin duda
Reviewed on Mar 3, 2026
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
Ave. San Martin, #455 Santa Cruz
The price is ￥21,382 per night from Mar 16 to Mar 17
￥21,382
￥21,382 total
Mar 16 - Mar 17
9/10 Wonderful! (363 reviews)
Very nice and cozy
Reviewed on Feb 28, 2026
Camino Real Hotel
Av. San Martín y 4to. Anillo Santa Cruz
The price is ￥19,878 per night from Apr 6 to Apr 7
￥19,878
￥19,878 total
Apr 6 - Apr 7
9/10 Wonderful! (420 reviews)
Spotless, large and comfortable room was well maintained. Friendly and helpful staff. Delicious breakfast buffet. Location is near excellent shopping and dining options.
Reviewed on Feb 5, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Discover the most popular places to visit in Santa Cruz
Plaza 24 de Septiembre
The heart of Santa Cruz lies in this public square, where locals relax and tourists sightsee in a welcoming, laid-back atmosphere.
Santa Cruz Zoo
Why not visit the native and exotic animals who call Santa Cruz Zoo home during your vacation in Santa Cruz? While in the area, you can find time to visit its shops.
What to do in Santa Cruz
Santa Cruz: Wildlife Sanctuary and Preservation Park Tour
￥13,252
per adult
Private Tour of Santa Cruz: We'll visit the center, Porongo, markets, and the river
￥9,355
per adult
4D/3N Expedition: Che Guevara Route - Disconnect from the World
￥124,572
per adult
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
