Santa Cruz Vacations

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Find the Best Santa Cruz Vacation Packages

Santa Cruz Hotel Deals

Ibis Santa Cruz DE LA Sierra

Ibis Santa Cruz DE LA Sierra

3 out of 5
AVENIDA CRISTOBAL DE MENDOZA Santa Cruz
The price is ￥6,727 per night from Jan 22 to Jan 23
￥6,727
￥6,727 total
Jan 22 - Jan 23
9.4/10 Exceptional! (80 reviews)
Amazing breakfast

Reviewed on Jan 7, 2026

Ibis Santa Cruz DE LA Sierra
Marriott Santa Cruz de la Sierra Hotel

Marriott Santa Cruz de la Sierra Hotel

5 out of 5
4to Anillo Entre Radial 23 Santa Cruz Santa Cruz
The price is ￥17,447 per night from Jan 16 to Jan 17
￥17,447
￥17,447 total
Jan 16 - Jan 17
9/10 Wonderful! (213 reviews)
Muy bien exelente

Reviewed on Dec 9, 2025

Marriott Santa Cruz de la Sierra Hotel
Sun Hotel

Sun Hotel

3.5 out of 5
Av. Banzer Km 13 Santa Cruz Santa Cruz
The price is ￥14,064 per night from Jan 10 to Jan 11
￥14,064
￥14,064 total
Jan 10 - Jan 11
8.2/10 Very Good! (333 reviews)
spotless

Reviewed on Dec 9, 2025

Sun Hotel
See all 292 properties in Santa Cruz
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Discover the most popular places to visit in Santa Cruz

Plaza 24 de Septiembre which includes heritage architecture and heritage elements as well as a large group of people

Plaza 24 de Septiembre

The heart of Santa Cruz lies in this public square, where locals relax and tourists sightsee in a welcoming, laid-back atmosphere.

Plaza 24 de Septiembre

Santa Cruz Zoo

Why not visit the native and exotic animals who call Santa Cruz Zoo home during your vacation in Santa Cruz? While in the area, you can find time to visit its shops.

Santa Cruz Zoo

What to do in Santa Cruz

Wildlife rescue center and preservation park

Santa Cruz: Wildlife Sanctuary and Preservation Park Tour

￥13,308
per adult
Santa Cruz: Wildlife Sanctuary and Preservation Park Tour
The Che Guevara route is the most peculiar tourist destination in Bolivia.

4D/3N Expedition: Che Guevara Route - Disconnect from the World

￥125,099
per adult
4D/3N Expedition: Che Guevara Route - Disconnect from the World
Trekking through the area of ​​​��​the last armed struggle of Che Guevara.

3D/2N Getaway on the Che Guevara Route Live the Adventure!

￥109,442
per adult
3D/2N Getaway on the Che Guevara Route Live the Adventure!
See all activities in Santa Cruz

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.