Santa Cruz Vacations

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Find the Best Santa Cruz Vacation Packages

Santa Cruz Hotel Deals

Camino Real Hotel

Camino Real Hotel

4.5 out of 5
Av. San Martín y 4to. Anillo, Equipetrol Norte, Santa Cruz
The price is ￥22,688 per night from Aug 23 to Aug 24
￥22,688
￥22,688 total
Aug 23 - Aug 24
8.8/10 Excellent! (394 reviews)
Best amenities
"Best amenities in a hotel , but need some upgrades"

Reviewed on Jul 16, 2025

Camino Real Hotel
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

3.5 out of 5
Ave. San Martin, #455, Santa Cruz
The price is ￥18,219 per night from Aug 21 to Aug 22
￥18,219
￥18,219 total
Aug 21 - Aug 22
8.8/10 Excellent! (321 reviews)
"Always an amazing hotel"

Reviewed on Jun 21, 2025

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

4.5 out of 5
San Martin Avenue Esq Street E - E, Santa Cruz
The price is ￥11,230 per night from Aug 15 to Aug 16
￥11,230
￥11,230 total
Aug 15 - Aug 16
9/10 Wonderful! (245 reviews)
"Location, surrounding, quietness, good service"

Reviewed on Jul 7, 2025

Hampton by Hilton Santa Cruz/Equipetrol, Bolivia
See all 272 properties in Santa Cruz
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Discover the most popular places to visit in Santa Cruz

Plaza 24 de Septiembre which includes heritage architecture and heritage elements as well as a large group of people

Plaza 24 de Septiembre

The heart of Santa Cruz lies in this public square, where locals relax and tourists sightsee in a welcoming, laid-back atmosphere.

Plaza 24 de Septiembre

Santa Cruz Zoo

Why not visit the native and exotic animals who call Santa Cruz Zoo home during your vacation in Santa Cruz? While in the area, you can find time to visit its shops.

Santa Cruz Zoo

What to do in Santa Cruz

Wildlife rescue center and preservation park

Santa Cruz: Wildlife Sanctuary and Preservation Park Tour

￥12,460
per adult
Santa Cruz: Wildlife Sanctuary and Preservation Park Tour
See all activities in Santa Cruz

Frequently asked questions

How much does a Santa Cruz vacation package cost?
You'll find cheap prices on Expedia for your Santa Cruz break. However, a range of factors like the hotel choice, length of stay and season will determine how much your vacation to Santa Cruz costs.
What are the cheapest months to go to Santa Cruz?
February, April and May are the best times to look for cheap Santa Cruz vacation packages. Opting to travel in quieter months means you can typically find lower prices on hotels and flights.
How many days is enough for Santa Cruz?
Typically, a handful of days is enough to tick off the main sights during your Santa Cruz vacation. However, if you prefer to have some time to kick back or take day tours, think about extending your itinerary.
Is it worth booking a vacation package to Santa Cruz?
Santa Cruz is a good vacation destination with attractions like Ventura Mall among the many things to keep you busy. Whether you're traveling with the family or getting away with friends, a Santa Cruz vacation promises a good time for everyone.
How to find the best Santa Cruz package deals?
Use Expedia's filters to help you find some tempting Santa Cruz package deals. When you start your search, simply set your maximum budget and then sort the results by "Price: low to high." If you're looking to save, plan your break for midweek, or look for Santa Cruz package deals in the off-peak season. Play around with your travel dates and you may land even better discounts. As a rule of thumb, it's usually best to lock in your vacation package as early as possible.
Is it cheaper to book a Santa Cruz vacation as a package?
You can enjoy significant savings on your Santa Cruz escape by booking a personalized vacation package. Click on the "Package" heading, then enter your travel dates and destination to browse some great hotel prices and airfares. Bundle everything into a great-value package and you can save hundreds of dollars. Consider adding a rental car and you may score a better deal.
When to book a vacation package to Santa Cruz?
If you're considering an impromptu Santa Cruz adventure, browse our last-minute deals that can be booked up to a week before you take off. Don't want to leave things to the last minute? You can find sensational deals on your flights and hotels by booking well in advance.
How to plan a trip to Santa Cruz?

  1. Choose your dates: What you want to do in Santa Cruz and your favorite season will help you decide when to get away.
  2. Work out your budget: Make sure you have enough money to pay for everything from transportation and dining out to experiences and flights. Your hotel will probably be the biggest expense during your trip to Santa Cruz.
  3. Work out your trip length: Consider how much time you want to spend discovering Santa Cruz. Plan your days so you can get to all the experiences and attractions you're interested in without rushing.
  4. Combine your hotel and flights: Epic destination, check. Length of stay, check. All that's left is to choose a Santa Cruz vacation package that brings all your bookings together.

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.