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Our top choices for Santa Cruz hotels

Exterior
Surbackpackers

Surbackpackers

Surbackpackers
3.0 star property
Santa Cruz
The price is ￥3,947
￥3,947 total
Jan 19 - Jan 20
Surbackpackers
Living area
Posada Express Fast Check

Posada Express Fast Check

Posada Express Fast Check
3.0 star property
Santa Cruz
10.0 out of 10, Exceptional, (2 reviews)
The price is ￥4,594
￥5,053 total
Jan 19 - Jan 20
Posada Express Fast Check
Reception
Lido Hotel

Lido Hotel

Lido Hotel
3.0 star property
Santa Cruz
9.0 out of 10, Wonderful, (31 reviews)
"Very helpful and nice staff. Quiet location. near the central plaza. Great value "
United Kingdom
David
The price is ￥7,229
￥7,229 total
Jan 19 - Jan 20
Lido Hotel
Standard Suite, 1 Queen Bed | Hypo-allergenic bedding, down comforters, desk, laptop workspace
Equipetrol Suites Apart Hotel

Equipetrol Suites Apart Hotel

Equipetrol Suites Apart Hotel
2.5 star property
Santa Cruz
8.8 out of 10, Excellent, (9 reviews)
"Perfect hotel"
Turkey
Yener
Equipetrol Suites Apart Hotel
Outdoor pool, open 9:00 AM to 8:00 PM, sun loungers
Premium Suites Deluxe Aparthotel Equipetrol

Premium Suites Deluxe Aparthotel Equipetrol

Premium Suites Deluxe Aparthotel Equipetrol
3.5 star property
Santa Cruz
9.0 out of 10, Wonderful, (82 reviews)
"Good price, great hotel!"
United States
James
The price is ￥6,158
￥6,158 total
Jan 12 - Jan 13
Premium Suites Deluxe Aparthotel Equipetrol
1 bedroom, in-room safe, desk, iron/ironing board
Apart Hotel Premium Suites Santa Cruz

Apart Hotel Premium Suites Santa Cruz

Apart Hotel Premium Suites Santa Cruz
3.5 star property
Santa Cruz
8.6 out of 10, Excellent, (98 reviews)
"Yes, staff were very friendly "
United States
veronica
Apart Hotel Premium Suites Santa Cruz
BBQ/picnic area
Casa Por Temporadas

Casa Por Temporadas

Casa Por Temporadas
2.0 star property
Santa Cruz
10.0 out of 10, Exceptional, (1 review)
"The front desk staff was amazing! We checked in during a rain storm and the hotel had been hit by lightning and their computers and they computers were out. The staff maintained their professionalism and got us in a room quickly. Thank you for your help "
United States
Cynthia
The price is ￥13,500
￥13,500 total
Jan 15 - Jan 16
Casa Por Temporadas
Seasonal outdoor pool
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
3.5 star property
Santa Cruz
9.0 out of 10, Wonderful, (352 reviews)
"Great spacious property with nice pool!"
United States
Douglas
The price is ￥20,684
￥20,684 total
Feb 6 - Feb 7
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
View from property
Hotel Continental Park

Hotel Continental Park

Hotel Continental Park
3.0 star property
Santa Cruz
8.8 out of 10, Excellent, (25 reviews)
"This is a great option for accomodations near the center of the city. Perhaps 5 or 6 block walk to the main square. Lots of options for restaurantes. The garage is easily accesible. The pool was great and we took advantage of the sauna. Breakfast was great as well. Good variety of food. Staff at the desk was polite and helpful. "
Canada
Gregory
The price is ￥10,655
￥10,655 total
Jan 18 - Jan 19
Hotel Continental Park
Lobby sitting area
Hotel Arenal

Hotel Arenal

Hotel Arenal
3.5 star property
Santa Cruz
7.6 out of 10, Good, (59 reviews)
"Perfect hotel in a central location!"
United States
Max
The price is ￥10,214
￥10,214 total
Jan 18 - Jan 19
Hotel Arenal
Exterior detail
TRYP by Wyndham Santa Cruz

TRYP by Wyndham Santa Cruz

TRYP by Wyndham Santa Cruz
4.0 star property
Santa Cruz
9.2 out of 10, Wonderful, (149 reviews)
"The hotel is well located, convenient for restaurants and shopping, and very quiet. We stayed in a 2-bedroom suite, very well appointed and comfortable. Love the design of the corridor! Staff are friendly and helpful. A bar at the dining area where breakfast is would be great."
United States
Vivian
The price is ￥15,631
￥15,631 total
Jan 12 - Jan 13
TRYP by Wyndham Santa Cruz
Outdoor pool, pool umbrellas, sun loungers
Marriott Santa Cruz de la Sierra Hotel

Marriott Santa Cruz de la Sierra Hotel

Marriott Santa Cruz de la Sierra Hotel
5.0 star property
Santa Cruz
9.0 out of 10, Wonderful, (213 reviews)
"Great hotel, food and location albeit a little expensive "
United States
Reinaldo
The price is ￥15,407
￥15,407 total
Feb 11 - Feb 12
Marriott Santa Cruz de la Sierra Hotel
Reception
Camino Real Hotel

Camino Real Hotel

Camino Real Hotel
4.5 star property
Santa Cruz
8.8 out of 10, Excellent, (411 reviews)
"The parrots. Unique"
United States
Juan P
The price is ￥28,484
￥28,484 total
Jan 12 - Jan 13
Camino Real Hotel
Lounge
Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

Hampton by Hilton Santa Cruz/Equipetrol, Bolivia
4.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (259 reviews)
"Nice hotel "
United States
Narciso Lorenzo
The price is ￥11,621
￥11,621 total
Feb 1 - Feb 2
Hampton by Hilton Santa Cruz/Equipetrol, Bolivia
Outdoor pool
Sun Hotel

Sun Hotel

Sun Hotel
3.5 star property
Santa Cruz
8.2 out of 10, Very Good, (333 reviews)
"Staff spoke English. Airport pickup beat any US hotel. Rooms nice. Restaurant was ok"
United States
Peter
The price is ￥14,153
￥14,153 total
Jan 16 - Jan 17
Sun Hotel
Restaurant
Prince Hotel

Prince Hotel

Prince Hotel
3.0 star property
Santa Cruz
The price is ￥8,526
￥8,842 total
Jan 12 - Jan 13
Prince Hotel
Dining room
Hotel BY Armonia SCZ

Hotel BY Armonia SCZ

Hotel BY Armonia SCZ
3.0 star property
Santa Cruz
8.4 out of 10, Very Good, (7 reviews)
"Very beautiful grounds. They were very responsive and accommodating. I enjoyed the hotel very much. "
United States
Kaerlig
Hotel BY Armonia SCZ
Front of property
Alfonsina Hotel Boutique by Inboccaluppo

Alfonsina Hotel Boutique by Inboccaluppo

Alfonsina Hotel Boutique by Inboccaluppo
3.5 star property
Santa Cruz
9.4 out of 10, Exceptional, (40 reviews)
"Love it. Will stay again!!"
United States
Juan
The price is ￥21,137
￥21,137 total
Jan 12 - Jan 13
Alfonsina Hotel Boutique by Inboccaluppo
Reception
Urban Suites

Urban Suites

Urban Suites
3.0 star property
Santa Cruz
The price is ￥8,468
￥8,468 total
Jan 12 - Jan 13
Urban Suites
Outdoor pool, sun loungers
Hotel Cortez

Hotel Cortez

Hotel Cortez
3.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (124 reviews)
"The staff and property are second to none! "
United States
Cynthia
The price is ￥20,533
￥20,533 total
Feb 6 - Feb 7
Hotel Cortez
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Great weekend hotel deals in Santa Cruz

Showing deals for:Jan 23 - Jan 25

Image gallery for HOTEL OSHO

Reception

HOTEL OSHO

3.5 star property
Santa Cruz
9.2/10Wonderful (38 reviews)
10% off
Price is ￥7,929
￥15,858 total
HOTEL OSHO
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Where to stay in Santa Cruz

Find the best Santa Cruz areas and neighborhoods for the activities you enjoy most. Learn more about Santa Cruz
Learn more about Santa Cruz

Hamacas

While Hamacas isn't home to many top sights, Santa Cruz Zoo and Las Brisas Shopping Center are some notable places to visit nearby.

Stay near popular Santa Cruz attractions

Plaza 24 de Septiembre showing street scenes

Plaza 24 de Septiembre

4.4/5 (70 reviews)
The heart of Santa Cruz lies in this public square, where locals relax and tourists sightsee in a welcoming, laid-back atmosphere.
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San Lorenzo Cathedral showing a church or cathedral and interior views

San Lorenzo Cathedral

4.5/5 (36 reviews)
One of the most iconic landmarks in Santa Cruz is the city’s mighty cathedral, which houses a museum displaying important artwork.
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Learn more about Santa Cruz

Tropical energy pulses through Plaza 24 de Septiembre, where locals gather under palm trees and the Metropolitan Cathedral's twin towers stand watch. Biocentro Güembé offers rainforest trails with butterfly gardens, while the massive Ventura Mall provides air-conditioned shopping when afternoon temperatures climb.

See all hotels in Santa Cruz
San Lorenzo Cathedral showing a garden

Top Santa Cruz Hotel Reviews

Lido Hotel

Lido Hotel

10/10 Excellent
"We stayed at the fabulous Lido Hotel for 2 nights in December 2025. The hotel is located in central Santa Cruz, within a 4 block walk from Plaza 24 de Septiembre, and also a short 10 minute walk from the iconic Cristo Redentor statue. Check in was quick and painless, and the front desk staff was friendly and helpful. The room itself was spacious, clean and comfortable, with a large attached full bathroom. The air conditioner did a great job of cooling the room. Breakfast was served each morning in the attached Chinese restaurant, and featured eggs, breakfast meats, fruits, juices, cereal and yogurt, and was a great way to fuel up before venturing out to explore Santa Cruz. Without equivocation, I highly recommend the Lido Hotel to anyone in search of a clean comfortable hotel at an affordable price in the enchanting metrolopolis of Santa Cruz de la Sierra, Bolivia. Dr. Kingstone Shih and Laura Meneses Los Altos, California USA "
kingstone 2-night trip
Posted 4 days ago
Lido Hotel

More cheap stays in Santa Cruz

Apartamento confortable para 2 personas

Apartamento confortable para 2 personas

Santa Cruz de la Sierra Departamento de Santa Cruz
The price is ￥3,474 per night from Jan 16 to Jan 17
￥3,474
￥6,632 total
Jan 16 - Jan 17

Frequently asked questions

What's the best place for a stay in Santa Cruz?
Ibis Santa Cruz DE LA Sierra is a favorite with Expedia customers. This hotel offers a restaurant and free parking. Reviews from our site also recommend Hampton by Hilton Santa Cruz/Equipetrol, Bolivia and Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel as top options for your trip. See all available top hotels, or vacation rentals in Santa Cruz.
What's the top vacation rental that Santa Cruz has to offer?
Casa Vida: Visitors give good reviews to this Santa Cruz vacation home rental, which is located in a rural location and has an outdoor pool, a patio, and a barbecue grill to put you at ease in your new surroundings. It has 3 bedrooms as well as a kitchen with a full-sized fridge, a stovetop, and a microwave, so you can cook with friends or family. Kick off your shoes and enjoy yourself with a private yard and a selection of games. Some other homes for rent in Santa Cruz include Cozy and independent. Downtown house JH. and Jose Luis Noya. See all vacation rentals in Santa Cruz.
If I need to cancel my hotel reservation in Santa Cruz, will I receive a refund?
Yes! Most hotel reservations are fully refundable as long as you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If your reservation is non-refundable, you might still have the option to cancel and get a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Santa Cruz.
Where can I learn more about changing or cancelling my trip to Santa Cruz?
To find more details about picking new dates or cancelling your trip to Santa Cruz, head over to our customer service page.
What's the best budget-friendly accommodation in Santa Cruz?
Based on our traveler reviews, residencial francia - Hostel is a top choice for a less expensive stay. Other choices for your budget-friendly stay include Nomad Hostel and Urubo Suite - Hostel. View all budget hotels in Santa Cruz.
What's the best accommodation for a family trip to Santa Cruz?
Marriott Santa Cruz de la Sierra Hotel is a hotel with an outdoor pool and a restaurant, and it's a top choice on Expedia for families. Other choices for your stay with the kids include Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel and Camino Real Hotel. Attractions like Santa Cruz Zoo and Play Land Amusement Park are also fun for kids of all ages. Find more child-friendly accommodations in Santa Cruz.
What is the top LGBTQ-friendly accommodation in Santa Cruz?
Hampton by Hilton Santa Cruz/Equipetrol, Bolivia is a top LGBTQ-friendly hotel that features free breakfast and free WiFi. Swissôtel Santa Cruz De La Sierra and Radisson Hotel Santa Cruz are other good choices for your trip. See all available hotels listed as LGBTQ-friendly in Santa Cruz.
What's the best pet-friendly hotel in Santa Cruz?
Ibis Santa Cruz DE LA Sierra is a top hotel for people traveling with their pets, and offers a restaurant and free WiFi for its human guests. Other good options for you and your pet's trip include HOTEL OSHO and Hotel LP Equipetrol. See more pet-friendly hotel accommodations in Santa Cruz.
Where is the best place to stay close to Plaza 24 de Septiembre?
Adjacent to Plaza 24 de Septiembre, Nomad Hostel is one of the top choices for your stay based on our traveler data, and this property offers a restaurant and a bar. Other good options close by include Senses Centro and Cosmopolitano Hotel Boutique.
What about the best place to stay near Ventura Mall?
One of the top choices for your stay is Camino Real Hotel, located next to Ventura Mall, and this 4-star hotel offers 2 bars and a restaurant. Los Tajibos Hotel And Convention Center and Marriott Santa Cruz de la Sierra Hotel are two other good choices in the immediate area.
What's the best luxury accommodation in Santa Cruz?
Marriott Santa Cruz de la Sierra Hotel is a luxury hotel with a full-service spa and a rooftop terrace, and it's a popular choice for Expedia travelers looking for an elegant place to stay. Camino Real Hotel and Hampton by Hilton Santa Cruz/Equipetrol, Bolivia are other upscale choices for your vacation. Find more luxury hotels in Santa Cruz.
What are some accommodations with pools in Santa Cruz?
Sun Hotel is a top hotel with a children's pool, an outdoor pool, and free buffet breakfast. A couple of other options that offer an onsite pool include Yotau All Suites Hotel and Buganvillas Hotel Suites & Spa. View all hotels with pools in Santa Cruz.
What is the best spa hotel in Santa Cruz?
Marriott Santa Cruz de la Sierra Hotel is a top luxury spa hotel featuring a rooftop terrace, a fitness center, tennis courts, and a bar. Spend an afternoon at Hotel Spa where you'll find massage treatments. Other popular spa hotels in Santa Cruz include Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel and Camino Real Hotel. See all spa hotels in Santa Cruz.
What's the best hotel for staying near Viru Viru International Airport (VVI)?
Sun Hotel is a popular 3.5-star hotel featuring free breakfast and a restaurant. It's located a short 1.3 mi (2.1 km) from Viru Viru Intl. Airport.
How is it to stay in Santa Cruz?
Visitors to Santa Cruz are sure to enjoy the shopping. Tourists can also enjoy the city's cafes, zoo, and cathedral. In Santa Cruz, there are 288 hotels and other accommodations to choose from. Find out more about Santa Cruz.
What should I do while I'm visiting Santa Cruz?
Cultural venues include Cine Center, Sacred Art Museum, and Ethno-folkloric Museum. Landmarks like San Lorenzo Cathedral, Plaza 24 de Septiembre, and Blacutt Square might be worth a visit. The picturesque setting of Guembe Biocenter and Lomas de Arena Regional Park exemplify the area's natural beauty. Check out what more to see and do in Expedia's Santa Cruz guide.
How should I get around Santa Cruz?
To see more of the larger area, ride aboard one of the trains from Santa Cruz de la Sierra Station. If you want to venture out around the area, you may want a rental car in Santa Cruz for your journey.
What's the weather like in Santa Cruz?
The hottest months are usually October and November with an average temp of 79°F, while the coldest months are June and July with an average of 70°F. Average annual precipitation for Santa Cruz is 48 inches.