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Find hotels in Santa Ana, Panama City from ¥5,069

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Discover 1,190 Santa Ana hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Sofitel Legend Casco Viejo, Panama City
5.0 star property
9.8 out of 10, Exceptional, (217)
"Lo máximo !!"
The price is ¥45,759
per night
Jun 1 - Jun 2
Sofitel Legend Casco Viejo, Panama City
Ramada Plaza By Wyndham Panama Punta Pacífica
4.0 star property
9.4 out of 10, Exceptional, (1002)
"Everything about this property was nice "
The price is ¥19,555
per night
Jun 11 - Jun 12
Ramada Plaza By Wyndham Panama Punta Pacífica
Bristol Panama, a Registry Collection Hotel
5.0 star property
9.2 out of 10, Wonderful, (1002)
"Nice Property "
The price is ¥29,792
per night
May 26 - May 27
Bristol Panama, a Registry Collection Hotel
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Hotel Riu Plaza Panama
5.0 star property
9.0 out of 10, Wonderful, (2408)
"The check-in process was soooo smooth. No anoying holds placed on my credit car. The included breakfast was absolutely amazing, and a very good deal for the price. Rooms and hotel ares were super clean. Very nice bar and dining options in the lobby. I'm already planning my return stay at the Riu Plaza. Absolutely amazing stress free experience!"
The price is ¥17,991
per night
May 19 - May 20
Hotel Riu Plaza Panama
Marriott Panama Hotel
4.0 star property
9.0 out of 10, Wonderful, (1000)
"I was a very pleasant experience."
The price is ¥22,473
per night
May 24 - May 25
Marriott Panama Hotel
AC Hotel by Marriott Panama City
3.5 star property
9.0 out of 10, Wonderful, (414)
"Hotel muy bien ubicado, staff muy amable y con una ubicación excelente muy cerca de Vía España."
The price is ¥14,893
per night
Jun 7 - Jun 8
AC Hotel by Marriott Panama City
Central Hotel Panama Casco Viejo
4.0 star property
9.0 out of 10, Wonderful, (682)
"This hotel is perfectly located in the Old Town. It has a wonderful old world elegance about it, but modern in all respects. The staff very friendly and professional. From the front desk, to the drivers, to the restaurant staff. Breakfast buffet is totally worth it. We would definitely stay again."
The price is ¥46,580
per night
May 20 - May 21
Central Hotel Panama Casco Viejo
Residence Inn by Marriott Panama City
4.0 star property
9.0 out of 10, Wonderful, (322)
"Nos encantó, muy cómodas habitaciones, muy bien equipadas, todo funcionó muy bien, excelente trato, las encargadas de limpieza muy amables. Excelente ubicación, sin duda de ahora en adelante será nuestra mejor opción cuando viajemos a Panamá."
The price is ¥19,868
per night
Jun 1 - Jun 2
Residence Inn by Marriott Panama City
Best Western Plus Panama Zen Hotel
4.0 star property
9.0 out of 10, Wonderful, (666)
"Very nice. "
The price is ¥12,353
per night
Jun 12 - Jun 13
Best Western Plus Panama Zen Hotel
Panama House Bed & Breakfast
2.5 star property
9.0 out of 10, Wonderful, (131)
"I really liked the HOT water in the shower - friendly staff - activities like the pool table, books, card games. The room and sheets were clean - towel provided - all very nice. The a/c worked but only starting at 6 pm so I couldn’t hang out in the room - but that’s ok - just didn’t know prior. The bed was firm/hard but better than others I’ve had. Pillow was lacking but ok. I would stay again."
The price is ¥5,069
per night
May 16 - May 17
Panama House Bed & Breakfast
JW Marriott Panama
5.0 star property
8.8 out of 10, Excellent, (1001)
"This hotel provides the best service."
The price is ¥29,911
per night
Jun 1 - Jun 2
JW Marriott Panama
W Panama
5.0 star property
8.8 out of 10, Excellent, (983)
"Great rooms and service "
The price is ¥27,792
per night
Jun 5 - Jun 6
W Panama
Las Americas Golden Tower Panama
4.0 star property
8.8 out of 10, Excellent, (869)
"We really enjoyed our time here. It was our first time in Panama. "
The price is ¥19,128
per night
May 26 - May 27
Las Americas Golden Tower Panama
Holiday Inn Panama Distrito Financiero, an IHG Hotel
4.0 star property
8.8 out of 10, Excellent, (1001)
"Liked restaurant, Breakfast very good. Room & bathroom very good size and very clean. Big study table, safe, Iron. Best was big size room and bath. "
The price is ¥12,672
per night
May 18 - May 19
Holiday Inn Panama Distrito Financiero, an IHG Hotel
Hotel Coral Suites
3.5 star property
8.8 out of 10, Excellent, (957)
"staff was great"
The price is ¥11,889
per night
May 16 - May 17
Hotel Coral Suites
Torres de Alba Hotel & Suites
3.5 star property
8.8 out of 10, Excellent, (362)
"Washer and dryer in too "
The price is ¥14,727
per night
May 16 - May 17
Torres de Alba Hotel & Suites
Marriott Executive Apartments Panama City, Finisterre
4.0 star property
8.8 out of 10, Excellent, (508)
"The staff was very friendly and helpful. The property was safe and clean. It was in a very convenient location, only 3 blocks from a grocery store. Additionally, there are several food places within walking distance to the property, including easy access to the Metro line. I had stayed at this location during a previous trip and it will be my primary location for all future trips."
The price is ¥14,893
per night
May 31 - Jun 1
Marriott Executive Apartments Panama City, Finisterre
Courtyard by Marriott Panama Multiplaza Mall
4.0 star property
8.8 out of 10, Excellent, (1000)
"Reception staff is smiling and welcoming "
The price is ¥25,202
per night
May 29 - May 30
Courtyard by Marriott Panama Multiplaza Mall
Sortis Hotel, Spa & Casino, Autograph Collection
4.5 star property
8.6 out of 10, Excellent, (825)
"Very good Hotel"
The price is ¥24,841
per night
May 17 - May 18
Sortis Hotel, Spa & Casino, Autograph Collection
InterContinental Miramar Panama, an IHG Hotel
4.0 star property
8.6 out of 10, Excellent, (393)
"Excelent option to stay iin Panama, close to every turist location and shopping areas"
The price is ¥26,908
per night
May 17 - May 18
InterContinental Miramar Panama, an IHG Hotel
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Other neighborhoods around Santa Ana

Hotels in top Panama City neighborhoods Learn more about Santa Ana

Santa Ana hotels information

Number of reviews
16,340
Accommodation
1,190 hotels
Lowest Price
¥5,069
Highest Price
¥46,580

Frequently asked questions

What's it like in Santa Ana?

Santa Ana is a neighborhood that travelers like for its seafood restaurants, shopping, and parks. Are you looking for Santa Ana travel tips? Be sure to check out Cinta Costera and Avenida Balboa while you're in the neighborhood.

Where is the best hotel for a stay in Santa Ana?

Based on Expedia customer reviews, Hotel República is the highest ranked property in Santa Ana. This hotel is a short 4-minute walk from Avenida Balboa, and it offers a rooftop terrace and free WiFi.

How many hotels can I expect to find in Santa Ana?

Expedia has 84 hotels and other accommodations in Santa Ana to choose from, making this an ideal home base for exploring the greater Panama City area.

If I need to cancel my hotel reservation in Santa Ana, will I receive a refund?

Yes! Most hotel room reservations are refundable provided that you cancel before the accommodation's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If you have a non-refundable reservation, it might still be possible to cancel it and be given a refund within a 24-hour period of your booking. Add dates, click "Search", then use the "fully refundable" filter to get top deals in Santa Ana.

Where can I learn more about changing or cancelling my trip to Santa Ana?

To find more details about picking new dates or cancelling your trip to Santa Ana, head over to our customer service page.

What is there to do in this Panama City neighborhood?

If you're looking forward to a day of shopping in Santa Ana, consider Avenida Central or Avenida Balboa, and pick out the perfect souvenir. A visit to Cinta Costera is also worth the trip while you're discovering the neighborhood. Albrook Shopping Mall, Amador Theater, and Museum of Contemporary Art Panama are just a few of the places to visit in and around Santa Ana. When you're sightseeing in Panama City, Mi Pueblito and Iglesia de la Merced are also worth a stop.

Recent reviews of Santa Ana hotels