Find hotels in San Sisto from ¥11,871

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Our top choices for San Sisto hotels

Giotto Hotel & Spa

Giotto Hotel & Spa
4.0 star property
Assisi Historic Center
8.8 out of 10, Excellent, (764)
"Very relaxing & restful hotel "
United States
Mary Davis
Giotto Hotel & Spa

Porsenna Resort

Porsenna Resort
Castiglione del Lago
9.4 out of 10, Exceptional, (46)
"Beautiful view and beautiful place to be out of town. "
United States
norma
The price is ¥25,823
¥28,699 total
includes taxes & fees
Dec 27 - Dec 28
Porsenna Resort

Il Palazzo

Il Palazzo
3.0 star property
Assisi Historic Center
9.6 out of 10, Exceptional, (463)
"Great and friendly staff. Good location. Good breakfast. Great clean room. Incredible views from the room."
Canada
Xavier
The price is ¥19,261
¥21,919 total
includes taxes & fees
Jan 7 - Jan 8, 2026
Il Palazzo

Hotel Fortuna

Hotel Fortuna
3.0 star property
Old Town Perugia
9.0 out of 10, Wonderful, (545)
"Fabulous location, great hotel "
Canada
Kristin
The price is ¥15,426
¥17,518 total
includes taxes & fees
Dec 22 - Dec 23
Hotel Fortuna

Hotel Boutique Castiglione del Lago

Hotel Boutique Castiglione del Lago
4.0 star property
Contrada Castello
9.8 out of 10, Exceptional, (45)
"Enjoyed our stay here, owners are super friendly! Our room was clean and comfortable and located next to shops and restaurants. Small town vibes, beautiful lake views. Perfect for a quick get away from busy life. Grazie mille! "
United States
Julie
The price is ¥19,290
¥21,512 total
includes taxes & fees
Dec 18 - Dec 19
Hotel Boutique Castiglione del Lago

BV Grand Hotel Assisi

BV Grand Hotel Assisi
4.0 star property
Assisi Historic Center
8.6 out of 10, Excellent, (314)
"Great if you have a car. Easy drive to Assisi. Good breakfast and large rooms and facilities. Indoor pool. Really comfortable. Easy drive to historic Assisi, there are 2 large parking lots with great access. Larger than hotels close "
United States
Jose F
The price is ¥14,039
¥16,541 total
includes taxes & fees
Dec 16 - Dec 17
BV Grand Hotel Assisi

Relais Il Canalicchio

Relais Il Canalicchio
4.0 star property
Collazzone
8.6 out of 10, Excellent, (121)
"A tiny medieval village restored back into a beautiful hotel. Staff was awesome. Loved it and will be back. "
United States
Nicole
Relais Il Canalicchio

Hotel Sangallo Palace

Hotel Sangallo Palace
4.0 star property
Perugia
8.8 out of 10, Excellent, (617)
"Great hotel with a fantastic staff and great accomodations"
United States
Steven
The price is ¥15,797
¥18,109 total
includes taxes & fees
Dec 16 - Dec 17
Hotel Sangallo Palace

Hotel Ristorante La Bastiglia

Hotel Ristorante La Bastiglia
4.0 star property
Spello
8.0 out of 10, Very Good, (79)
"Clean rooms great views. Make sure you check in early since a parking permit is necessary. "
United States
Gennaro
The price is ¥11,016
¥13,397 total
includes taxes & fees
Dec 16 - Dec 17
Hotel Ristorante La Bastiglia

Asisium Boutique Hotel

Asisium Boutique Hotel
4.0 star property
Assisi Historic Center
9.2 out of 10, Wonderful, (127)
"Very modern and up to date with comfortable bed and large shower with excellent water pressure"
United States
Adam
The price is ¥22,312
¥25,642 total
includes taxes & fees
Jan 15 - Jan 16, 2026
Asisium Boutique Hotel

I Borghi dell'Eremo

I Borghi dell'Eremo
Piegaro
10.0 out of 10, Exceptional, (54)
"Beautiful grounds, room:suites, impeccable staff made a wonderful relaxing time but still have our favorite small villages to explore "
United States
Donna
The price is ¥53,046
¥58,351 total
includes taxes & fees
Dec 16 - Dec 17
I Borghi dell'Eremo

Relais Paradiso

Relais Paradiso
Gualdo Cattaneo
9.2 out of 10, Wonderful, (10)
"We really enjoyed our stay at the Relais. The hotel Is in the Heart of Umbria's Hills. From the hotel you can have a wonderful view of the green landscape. Our room was big enough for 2, with all the comforts. Everything was clean and new, the bed really comfortable. We used the spa and I need to mention Francesca for her service. Actually, at the Relais all the staff members were all.nice and kind with the guests."
United Kingdom
Luigi
The price is ¥19,576
¥21,533 total
includes taxes & fees
Dec 16 - Dec 17
Relais Paradiso

Rosetta Hotel Perugia, Tapestry Collection by Hilton

Rosetta Hotel Perugia, Tapestry Collection by Hilton
5.0 star property
Old Town Perugia
10.0 out of 10, Exceptional, (1)
"Stanza impeccabile, personale cortese. Un po’ tardo l’orario del check-in"
Italy
Giordano
The price is ¥17,668
¥20,350 total
includes taxes & fees
Dec 18 - Dec 19
Rosetta Hotel Perugia, Tapestry Collection by Hilton

Hotel Fontebella

Hotel Fontebella
4.0 star property
Assisi Historic Center
8.6 out of 10, Excellent, (632)
"Fantastic views and staff"
United States
Nancy
Hotel Fontebella

TH Assisi - Hotel Cenacolo

TH Assisi - Hotel Cenacolo
4.0 star property
Assisi
9.2 out of 10, Wonderful, (611)
"Nice place to stay"
United States
José Felipe Casillas
The price is ¥11,409
¥13,647 total
includes taxes & fees
Jan 11 - Jan 12, 2026
TH Assisi - Hotel Cenacolo

Ripa Relais Colle del Sole

Ripa Relais Colle del Sole
Perugia
9.4 out of 10, Exceptional, (145)
"Host very nice, amazing view, great breakfast: everything you need to rest a bit outside the city"
Italy
Ilaria
Ripa Relais Colle del Sole

Windsor Savoia

Windsor Savoia
3.0 star property
Assisi
9.0 out of 10, Wonderful, (91)
"Great staff"
United States
Teresita L
The price is ¥21,800
¥24,712 total
includes taxes & fees
Jan 8 - Jan 9, 2026
Windsor Savoia

Hotel Monastero Sant'Andrea

Hotel Monastero Sant'Andrea
Assisi Historic Center
9.6 out of 10, Exceptional, (38)
"Very nice place to stay "
United States
maria m
The price is ¥12,841
¥14,857 total
includes taxes & fees
Dec 17 - Dec 18
Hotel Monastero Sant'Andrea

Hotel Lidò

Hotel Lidò
4.0 star property
Passignano sul Trasimeno
8.0 out of 10, Very Good, (144)
"Great visit "
Mexico
Francisco
Hotel Lidò

Antico Sipario Boutique Hotel, BW Signature Collection

Antico Sipario Boutique Hotel, BW Signature Collection
Paciano
10.0 out of 10, Exceptional, (13)
"We loved the place! Claudio the manager was very kind The landscape is just magnificent! I want to come back!"
United States
Sonia
The price is ¥20,731
¥23,097 total
includes taxes & fees
Dec 21 - Dec 22
Antico Sipario Boutique Hotel, BW Signature Collection
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

Where is the best place to stay in San Sisto?
TH Assisi - Hotel Cenacolo, located 12.3 mi (19.9 km) from the heart of San Sisto, is a top choice for your stay based on our traveler data. Two other choices for your visit to the area are La Meridiana Bleisure Hotel and Giotto Hotel & Spa. See all available top hotels, or vacation rentals in San Sisto.
What are some of the best vacation home rentals that San Sisto has to offer?
Agriturismo Marano: This vacation home rental outside San Sisto offers a terrace, a garden, and a barbecue grill to help you feel perfectly comfortable in your new surroundings. Kitchen amenities include a fridge, a stovetop, and kitchenware. See all vacation rentals in San Sisto.
If I need to cancel my hotel reservation in San Sisto, will I receive a refund?
Yes, the majority of hotel bookings are fully refundable provided that you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before the scheduled arrival. If you have a non-refundable reservation, you might still have the option to cancel and be given a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in San Sisto.
Where can I learn more about changing or cancelling my trip to San Sisto?
For more details about picking new dates or cancelling your trip to San Sisto, head over to our customer service page.
What are some hotels with pools in San Sisto?
La Meridiana Bleisure Hotel: Offers a children's pool, a seasonal outdoor pool, and a rooftop terrace. Sina Brufani and Hotel Sangallo Palace are two additional hotels that offer an onsite pool. View all hotels with pools in San Sisto.
What is the best accommodation for staying close to Falconara Airport (AOI)?
Hotel Touring Falconara Marittima is one of the top choices for your stay and is a popular 3-star hotel featuring a roundtrip airport shuttle and an airport shuttle. It's located 2.7 mi (4.3 km) from Falconara Airport. Other choices near the airport include Residenza Leonardo and Tenuta Villa Colle Sereno.
What is staying in San Sisto like?
Those traveling to San Sisto are sure to enjoy the sights to see and things to do. In San Sisto, there are 5 hotels and other accommodations to choose from. Find out more about San Sisto.
What should I do while I'm visiting San Sisto?
A favorite place to visit is Perugina Chocolate Factory. You'll also find Renato Curi Stadium and Citta della Domenica in the area. Check out what more to see and do in Expedia's San Sisto guide.
What's the best way to get around San Sisto?
To see more of the larger area, hop on a train at Perugia Silvestrini Station. If you want to venture out around the area, you may want a rental car in San Sisto for your journey.
What's the seasonal weather like in San Sisto?
The hottest months are usually August and July with an average temp of 72°F, while the coldest months are January and February with an average of 44°F. Average annual precipitation for San Sisto is 37 inches.

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