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Our top choices for McClure hotels

A pantry stocked with various snacks and food items.
A living room with a stone fireplace, a television mounted above it, and a large sofa with cushions.
A spacious hotel lobby with a high ceiling, a central seating area with sofas and chairs, a fireplace, and a television mounted on the wall.
A spacious lobby with a fireplace, comfortable seating, a staircase, and a large chandelier.

1. Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Cape Girardeau
United States
Rebecca
￥15,012
￥17,086 total
includes taxes & fees
Nov 15 - Nov 16
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
A spacious lobby with a curved staircase, large windows, and a seating area with a rug.
A modern bar area with a herringbone patterned wall, a long counter with bar stools, and a variety of bottles and glasses.
A hotel room with two beds, a desk, a chair, and a view of the city.
A modern living room with a large sectional sofa, a flat-screen TV, and a view of the sea through large windows.

2. The Riverview

The Riverview
Cape Girardeau
United States
Scotty
￥16,075
￥18,135 total
includes taxes & fees
Oct 22 - Oct 23
The Riverview
A hotel room with a large bed, two bedside lamps, a chair, and a wooden headboard.
A bowl of cereal with raisins and milk, a half orange, and a sandwich on a table with a yellow napkin.
A breakfast setting with waffles, scrambled eggs, toast, a glass of orange juice, and a white mug on a table with a green placemat.
A plate of mixed greens salad with cherry tomatoes and croutons, a bowl of baked pasta, and a glass of red wine on a wooden table.

3. Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau
Cape Girardeau
United States
DENNIS
￥14,220
￥16,043 total
includes taxes & fees
Oct 23 - Oct 24
Drury Inn & Suites Cape Girardeau
A hotel room with a blue sofa, an orange ottoman, a desk with a lamp, a television, and a window with curtains.
A modern dining area with wooden tables and chairs, a kitchen area with a tiled backsplash, and framed pictures on the wall.
A hotel room with two beds, a window with curtains, an air conditioning unit, and a lamp on a nightstand.
A Dear Tree Inn building with a covered entrance and a clear sky at dusk.

4. Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West
Cape Girardeau
United States
Troy
￥11,376
￥12,834 total
includes taxes & fees
Oct 25 - Oct 26
Pear Tree Inn Cape Girardeau West
A spacious lobby with a circular seating area, a stone fireplace, and modern lighting fixtures.
A spacious lobby with a curved seating area, a reception desk, and a large window providing natural light.
A Drury Plaza Hotel with a modern design, featuring a prominent entrance, multiple floors, and a clear sky.
A spacious corridor with a high ceiling, recessed lighting, and a series of posters on the walls.

5. Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center
Cape Girardeau
United States
Darnetta
￥15,800
￥17,825 total
includes taxes & fees
Oct 22 - Oct 23
Drury Plaza Hotel Cape Girardeau Conference Center
A spacious dining area with high ceilings, large windows, and modern lighting fixtures.
A hotel room with a bed, a desk with a television, a chair, a suitcase, and a map on the wall.
An outdoor patio with stone walls, wicker furniture, and large windows.
A gym with exercise equipment, a treadmill, and a wall-mounted TV.

6. Hampton Inn Cape Girardeau I 55 East

Hampton Inn Cape Girardeau I 55 East
Cape Girardeau
United States
Rebekah
￥16,715
￥18,857 total
includes taxes & fees
Oct 25 - Oct 26
Hampton Inn Cape Girardeau I 55 East
A modern living room with a sofa, armchairs, a coffee table, and a TV mounted on the wall.
A Fairfield by Marriott hotel with a modern design, featuring a stone facade, multiple floors, and a well-lit entrance.
A modern living room with a sofa, a coffee table, and a dining area with chairs and a table.
A reception area with a wooden reception desk, a glass door leading to a storage room, and a decorative wall piece.

7. Fairfield Inn & Suites by Marriott Cape Girardeau

Fairfield Inn & Suites by Marriott Cape Girardeau
Cape Girardeau
United States
Carlos
￥15,984
￥18,032 total
includes taxes & fees
Oct 25 - Oct 26
Fairfield Inn & Suites by Marriott Cape Girardeau
A hotel entrance with a large sign reading "LAQUINTA" and a sun graphic.
An outdoor patio with tables and chairs, a stone wall, and large windows.
A hotel room with two beds, a nightstand, a lamp, and a chair.
A breakfast bar with a coffee machine, waffle maker, toaster, and various food items.

8. La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
Jackson
United States
Elaine
￥12,626
￥13,664 total
includes taxes & fees
Nov 1 - Nov 2
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
A spacious lobby with marble flooring, elegant seating, and a grand staircase.
A Courtyard by Marriott hotel with a modern brick facade, large windows, and a covered entrance area.
A spacious living room with a sofa set, a coffee table, and a dining area.
A lobby with seating areas, a reception desk, and a bar.

9. Courtyard by Marriott Cape Girardeau Downtown

Courtyard by Marriott Cape Girardeau Downtown
Cape Girardeau
United States
Kristin
￥19,768
￥22,400 total
includes taxes & fees
Oct 28 - Oct 29
Courtyard by Marriott Cape Girardeau Downtown
A modern retail area with a display of local items and snacks.
A hotel room with two beds, a desk, a chair, a TV, and a window with a view.
An outdoor patio area with seating arrangements, including a sofa and chairs, and a table.
A modern indoor seating area with blue sofas and tables, a patterned carpet, and large windows offering a view of the outdoors.

10. Tru By Hilton Cape Girardeau

Tru By Hilton Cape Girardeau
Cape Girardeau
United States
Shannon
￥14,124
￥16,076 total
includes taxes & fees
Oct 25 - Oct 26
Tru By Hilton Cape Girardeau
A spacious lobby with large windows, comfortable seating, and a modern ceiling design.
A gym with treadmills, an elliptical, a bench, and a rack of dumbbells.
A breakfast bar with coffee machines, a cereal dispenser, and a fruit display.
A room with large windows, two red upholstered chairs, a small table, and a potted plant.

11. Comfort Suites Jackson-Cape Girardeau

Comfort Suites Jackson-Cape Girardeau
Jackson
United States
VICTORIA
￥11,954
￥12,938 total
includes taxes & fees
Nov 8 - Nov 9
Comfort Suites Jackson-Cape Girardeau
A hotel with a modern design, featuring a prominent sign for Candlewood Suites. There are multiple parking spaces visible in front of the building.
A hotel room with a bed, a TV, a desk, and a chair.
An indoor swimming pool with tiled flooring, a seating area with chairs, and a staircase leading to a door.
A hotel patio with a gazebo, outdoor seating, and a view of the road.

12. Candlewood Suites Cape Girardeau by IHG

Candlewood Suites Cape Girardeau by IHG
Cape Girardeau
United States
Samuel
￥11,377
￥13,705 total
includes taxes & fees
Nov 1 - Nov 2
Candlewood Suites Cape Girardeau by IHG
A spacious living area with a high ceiling, a green accent wall, and a wooden balcony railing.
A reception desk with a green wall, a wooden door, and a sign that reads 'QUALITY INN.'
A restaurant with multiple tables and chairs, an exit sign, a television, and a counter with food items.
A hotel room with a large bathtub, a bed with a wooden headboard, a nightstand with a lamp, and a painting of a building on the wall.

13. Quality Inn Cape Girardeau North

Quality Inn Cape Girardeau North
Cape Girardeau
United States
Dayanita
￥9,401
￥10,606 total
includes taxes & fees
Nov 1 - Nov 2
Quality Inn Cape Girardeau North
A spacious lobby with a large sectional sofa, multiple armchairs, and a coffee table. There is a TV mounted on the wall and a large window providing a view of the outdoors.
A Drury Inn & Suites building with a traditional architectural style, featuring a covered entrance and multiple windows.
A restaurant with a brick wall, a flat-screen TV, and a bar area.
An indoor swimming pool with a wooden ceiling, lounge chairs, and a lifeguard chair.

14. Drury Inn & Suites Jackson MO

Drury Inn & Suites Jackson MO
Jackson
United States
Lyn
￥12,640
￥13,363 total
includes taxes & fees
Nov 1 - Nov 2
Drury Inn & Suites Jackson MO
A hotel room with a bed, desk, chair, television, and two wall-mounted lamps.
A hotel room with a kitchenette, a bed, a dining table with chairs, a TV mounted on the wall, and a dresser.
A bathroom with a marble wall and a white bathtub.
A hotel room with a large bed, two bedside tables, a nightstand, a telephone, and two wall-mounted lamps.

15. Town House Inn Cape Giradreau

Town House Inn Cape Giradreau
Cape Girardeau
United States
Hope
￥11,061
￥12,921 total
includes taxes & fees
Oct 19 - Oct 20
Town House Inn Cape Giradreau
A kitchen with dark wooden cabinets, a stainless steel refrigerator, a black stove, a microwave, and a sink.
A trophy labeled "Town House Inn" with "Cape Girardeau County, Missouri" and "2025" on it.
A hotel room with two beds, a wooden dresser, a bathroom with a shower, and a kitchen area.
Exterior

16. Town House Inn

Town House Inn
Jackson
United States
Jennifer
￥11,263
￥12,190 total
includes taxes & fees
Oct 19 - Oct 20
Town House Inn
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Top McClure Hotel Reviews

Courtyard by Marriott Cape Girardeau Downtown

Courtyard by Marriott Cape Girardeau Downtown

10/10 Excellent
"I was surprised how reasonable the cost was considering how clean & nice all of the finishers were."
John 1-night trip
Posted 1 day ago
Courtyard by Marriott Cape Girardeau Downtown
Drury Inn & Suites Jackson MO

Drury Inn & Suites Jackson MO

10/10 Excellent
"Lovely hotel. Extremely happy with the accommodations. The hotel and room was very clean. The complimentary dinner was delicious. The pool area and workout room were clean and pleasant. Cute courtyard. Very happy with the service!"
Katie 1-night trip
Posted 1 day ago
Drury Inn & Suites Jackson MO
Hampton Inn Cape Girardeau I 55 East

Hampton Inn Cape Girardeau I 55 East

8/10 Good
"It was good. No complaints. The walls weren't terrible. No smells. It was clean & nice."
John 1-night trip
Posted 2 days ago
Hampton Inn Cape Girardeau I 55 East
Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West

10/10 Excellent
"We have stayed at the Pear Tree several times and never disappointed!! Great staff, clean rooms, generous breakfast. A special thanks to Lydia who took extra care to make our last stay remarkable. Thank you."
Sally 1-night trip
Posted 3 days ago
Pear Tree Inn Cape Girardeau West
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

10/10 Excellent
"We have stayed here a number of times over 20 years. It’s always clean and well maintained. Breakfast is very good. Staff is always friendly and helpful."
John 3-night trip
Posted 4 days ago
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Amazing Lakeside hot tub, A-frame 3 King Beds, Shawnee Forest sleeps 2-6 Firepit

Amazing Lakeside hot tub, A-frame 3 King Beds, Shawnee Forest sleeps 2-6 Firepit

10/10 Excellent
"Loved staying here for my bachelorette trip, will definitely be back!"
Courtney G. 2-night trip
Posted 5 days ago
Amazing Lakeside hot tub, A-frame 3 King Beds, Shawnee Forest sleeps 2-6 Firepit
* On the Wine Trail * Hot Tub * Wi-Fi *

* On the Wine Trail * Hot Tub * Wi-Fi *

10/10 Excellent
"Had a great time!!! It was nice to relax in the hot tub each night after full days on the wine trail. Great host!!!"
scott 2-night trip
Posted 8 days ago
* On the Wine Trail * Hot Tub * Wi-Fi *
Cabin in Southern Illinois - Hot Tub - Romantic Getaway -Shawnee National Forest

Cabin in Southern Illinois - Hot Tub - Romantic Getaway -Shawnee National Forest

10/10 Excellent
"Everything was perfect for a relaxing, romantic weekend away!"
Weston W. 2-night trip
Posted 13 days ago
Cabin in Southern Illinois - Hot Tub - Romantic Getaway -Shawnee National Forest
Rest, Relax and Renew. Our log cabin experience awaits your arrival.

Rest, Relax and Renew. Our log cabin experience awaits your arrival.

8/10 Good
"The cabin was super clean. We caught bass in the pond. The location was very peaceful yet close to town.we would book again."
Donna S. 2-night trip
Posted 3 weeks ago
Rest, Relax and Renew. Our log cabin experience awaits your arrival.

More cheap stays in McClure

Quality Inn Cape Girardeau North

Quality Inn Cape Girardeau North

2011 North Kingshighway Cape Girardeau MO
￥9,401
￥10,606 total
Nov 1 - Nov 2
includes taxes & fees
Quality Inn Cape Girardeau North
Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West

103 Cape West Pkwy Cape Girardeau MO
￥11,376
￥12,834 total
Oct 25 - Oct 26
includes taxes & fees
9.2/10 Wonderful! (1,004 reviews)
Pear Tree Inn Cape Girardeau West
Candlewood Suites Cape Girardeau by IHG

Candlewood Suites Cape Girardeau by IHG

485 S Mount Auburn Rd Cape Girardeau MO
￥11,377
￥13,705 total
Nov 1 - Nov 2
includes taxes & fees
Candlewood Suites Cape Girardeau by IHG
Tru By Hilton Cape Girardeau

Tru By Hilton Cape Girardeau

2520 Veterans Memorial Dr Cape Girardeau MO
￥14,124
￥16,076 total
Oct 25 - Oct 26
includes taxes & fees
Tru By Hilton Cape Girardeau
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

3253 William Street Cape Girardeau MO
￥15,012
￥17,086 total
Nov 15 - Nov 16
includes taxes & fees
9.4/10 Exceptional! (1,000 reviews)
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Hotel 7 Inn Anna

Hotel 7 Inn Anna

100 Richview Dr Anna IL
Get ratesHotel 7 Inn Anna

Frequently asked questions

What's the best place for a stay in McClure?
Located 8.2 mi (13.2 km) from the heart of McClure, Drury Plaza Hotel Cape Girardeau Conference Center is a top choice for your stay based on our traveler data. Other good options for your stay in the area are Pear Tree Inn Cape Girardeau West and The Riverview. See all available top hotels, or vacation rentals in McClure.
What's the top vacation rental that McClure has to offer?
On the Wine Trail Hot Tub Wi-Fi : This vacation home rental near McClure is located on a lake and has a patio, a hot tub, and a barbecue grill to put you at ease in your new surroundings. Kitchen amenities include a fridge, a stovetop, and a microwave. See all vacation rentals in McClure.
If I need to cancel my hotel reservation in McClure, will I receive a refund?
Yes, most hotel reservations are refundable provided that you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of your check-in date. If you have a non-refundable reservation, it may still be possible to cancel it and be given a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in McClure.
Where can I learn more about changing or cancelling my trip to McClure?
For additional details about changing or cancelling your trip to McClure, click here.
What is staying in McClure like?
Those traveling to McClure are sure to enjoy the sights to see and things to do. There are 147 hotels and other accommodations in the surrounding area. Find out more about McClure.
What should I do while I'm visiting McClure?
A favorite place to visit is Devil's Island Wildlife Management Area. You'll also find Century Casino & Hotel Cape Girardeau and Hunter Valley Winery in the area. Check out what more to see and do in Expedia's McClure guide.
What's the seasonal weather like in McClure?
The hottest months are usually July and August with an average temp of 76°F, while the coldest months are January and February with an average of 40°F. Average annual precipitation for McClure is 59 inches.

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