Find hotels in Mayo, FL from ￥6,570

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Dec 24 - Dec 25
Tomorrow
Dec 25 - Dec 26
This weekend
Dec 26 - Dec 28
Next weekend
Jan 2 - Jan 4

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Our top choices for Mayo hotels

BBQ/picnic area
Cindys Motel

Cindys Motel

Cindys Motel
2.5 star property
Mayo
8.8 out of 10, Excellent, (128)
"Nice place"
Australia
Marie
Cindys Motel
Classic Cabin, Resort View | Terrace/patio
Suwannee River Rendezvous

Suwannee River Rendezvous

Suwannee River Rendezvous
2.5 star property
Mayo
8.6 out of 10, Excellent, (19)
"Always a good time!"
United States
Madalaine
The price is ￥4,047
￥6,570 total
includes taxes & fees
Jan 7 - Jan 8, 2026
Suwannee River Rendezvous
Free daily buffet breakfast
Holiday Inn Express & Suites Live Oak by IHG

Holiday Inn Express & Suites Live Oak by IHG

Holiday Inn Express & Suites Live Oak by IHG
2.5 star property
Live Oak
8.4 out of 10, Very Good, (775)
"Have stayed here whenever we are in town. Always god stay."
United States
Gregg
The price is ￥18,922
￥20,816 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Holiday Inn Express & Suites Live Oak by IHG
Free daily full breakfast
Best Western Plus Madison

Best Western Plus Madison

Best Western Plus Madison
2.5 star property
Madison
8.0 out of 10, Very Good, (574)
"Clean room, friendly staff, good breakfast."
United States
erik
The price is ￥17,562
￥19,757 total
includes taxes & fees
Jan 15 - Jan 16, 2026
Best Western Plus Madison
Dining
Putnam Lodge Hotel and Spa

Putnam Lodge Hotel and Spa

Putnam Lodge Hotel and Spa
2.5 star property
Cross City
9.2 out of 10, Wonderful, (363)
"Historic! "
United States
William
The price is ￥24,979
￥27,477 total
includes taxes & fees
Jan 16 - Jan 17, 2026
Putnam Lodge Hotel and Spa
Lobby
Econo Lodge Live Oak

Econo Lodge Live Oak

Econo Lodge Live Oak
2.0 star property
Live Oak
7.0 out of 10, Good, (277)
"need grab bars"
United States
Frances and Edward
The price is ￥10,218
￥11,240 total
includes taxes & fees
Jan 22 - Jan 23, 2026
Econo Lodge Live Oak
LCD TV
Royal Inn Motel

Royal Inn Motel

Royal Inn Motel
2.0 star property
Perry
8.8 out of 10, Excellent, (988)
"Check in and check out was quick, convenient. It was a pleasure staying here. I will stay here again when in town."
United States
Darla
The price is ￥12,333
￥13,813 total
includes taxes & fees
Jan 2 - Jan 3, 2026
Royal Inn Motel
Exterior
Quality Inn & Suites Live Oak I-10 Exit 283

Quality Inn & Suites Live Oak I-10 Exit 283

Quality Inn & Suites Live Oak I-10 Exit 283
2.5 star property
Live Oak
7.0 out of 10, Good, (518)
"Staff was very friendly, check-in was super fast, decent room, neat and clean, comfy veds, big towels, breakfast was ok."
United States
Charlotte
The price is ￥15,514
￥17,065 total
includes taxes & fees
Jan 22 - Jan 23, 2026
Quality Inn & Suites Live Oak I-10 Exit 283
Free daily on-the-go breakfast
Days Inn by Wyndham Madison

Days Inn by Wyndham Madison

Days Inn by Wyndham Madison
2.0 star property
Madison
7.0 out of 10, Good, (575)
"Room was clean. Everyone was very courteous!"
United States
Al
The price is ￥11,593
￥13,042 total
includes taxes & fees
Dec 30 - Dec 31
Days Inn by Wyndham Madison
Deluxe Cabin | Private kitchen | Stovetop, coffee/tea maker, toaster, cookware/dishes/utensils
Good Times Motel and Marina

Good Times Motel and Marina

Good Times Motel and Marina
2.0 star property
Steinhatchee
9.4 out of 10, Exceptional, (72)
"Fantastic stay! Beautiful cabin and Tiny was a great host. The restaurant was great too. Would love to go back."
United States
Josh
The price is ￥13,910
￥15,301 total
includes taxes & fees
Jan 15 - Jan 16, 2026
Good Times Motel and Marina
Room, 1 King Bed, Non Smoking | Blackout drapes, free cribs/infant beds, free WiFi, bed sheets
Super 8 by Wyndham Madison

Super 8 by Wyndham Madison

Super 8 by Wyndham Madison
2.0 star property
Madison
7.4 out of 10, Good, (633)
"Nice place "
United States
James
The price is ￥11,300
￥12,713 total
includes taxes & fees
Dec 30 - Dec 31
Super 8 by Wyndham Madison
Exterior
Steinhatchee River Inn

Steinhatchee River Inn

Steinhatchee River Inn
2.0 star property
Steinhatchee
9.4 out of 10, Exceptional, (385)
"Friendly staff and clean room"
United States
Pegg
The price is ￥21,701
￥24,305 total
includes taxes & fees
Jan 14 - Jan 15, 2026
Steinhatchee River Inn
Free buffet breakfast
Holiday Inn Express Hotel & Suites PERRY by IHG

Holiday Inn Express Hotel & Suites PERRY by IHG

Holiday Inn Express Hotel & Suites PERRY by IHG
2.5 star property
Perry
8.6 out of 10, Excellent, (705)
"Good staff "
United States
Emmett
The price is ￥22,169
￥24,829 total
includes taxes & fees
Jan 2 - Jan 3, 2026
Holiday Inn Express Hotel & Suites PERRY by IHG
Lobby sitting area
Hampton Inn Perry

Hampton Inn Perry

Hampton Inn Perry
2.5 star property
Perry
8.6 out of 10, Excellent, (723)
"Nice place to stay in a small town"
United States
Joyce
The price is ￥19,075
￥21,364 total
includes taxes & fees
Jan 20 - Jan 21, 2026
Hampton Inn Perry
Front of property
Fiddler's Restaurant and Resort

Fiddler's Restaurant and Resort

Fiddler's Restaurant and Resort
2.0 star property
Steinhatchee
8.6 out of 10, Excellent, (287)
"great place"
United States
mike
The price is ￥16,045
￥17,970 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Fiddler's Restaurant and Resort
Front of property
Skylark Motel

Skylark Motel

Skylark Motel
2.5 star property
Perry
6.0 out of 10, (47)
"No wifi.... but very clean room. This is a very small motor-inn. It was great for a single night traveling through the area."
United States
Brian
Skylark Motel
Reception
Carriage Inn Motel

Carriage Inn Motel

Carriage Inn Motel
2.0 star property
Cross City
5.6 out of 10, (128)
"I would sleep in my own car in a Loves truck stop before staying here again. "
United States
Heather
Carriage Inn Motel
Exterior
Regency Inn

Regency Inn

Regency Inn
2.5 star property
Perry
5.2 out of 10, (225)
"The front desk staff was wonderful. It was decent for a one night stay only."
United States
Dale
The price is ￥14,250
￥15,961 total
includes taxes & fees
Dec 25 - Dec 26
Regency Inn
Lobby
Cross City Motel by Hotel O Hwy 98

Cross City Motel by Hotel O Hwy 98

Cross City Motel by Hotel O Hwy 98
2.5 star property
Cross City
3.8 out of 10, (6)
"Do not stay here! Dirty, disgusting place with live bugs to keep you company."
United States
Ryan
The price is ￥10,198
￥11,218 total
includes taxes & fees
Dec 25 - Dec 26
Cross City Motel by Hotel O Hwy 98
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular Mayo attractions

Lafayette Blue Springs State Park

Dive into this first-magnitude spring's crystal-clear waters flowing beneath a natural limestone bridge. Explore underwater caves or paddle to the iconic Suwannee River amid moss-draped oaks.
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Perry Spring

Perry Spring offers crystal-clear 72-degree waters where you can swim from a jumping platform into the Suwannee River. Relax at the covered pavilion with fire pit or lounge on the river deck with floating dock.
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Learn more about Mayo

Paddle through crystal-clear waters at Lafayette Blue Springs State Park where swimming and snorkeling reveal underwater caves and limestone formations. Explore the peaceful Suwannee River by kayak or visit Perry Spring, where locals gather for refreshing dips during hot summer afternoons.

See all hotels in Mayo
kayakers at Rock Bluff Spring on the Suwanneee River, Gilchrist County, Florida

Top Mayo Hotel Reviews

Holiday Inn Express & Suites Live Oak by IHG

Holiday Inn Express & Suites Live Oak by IHG

10/10 Excellent
"Everything was clean and comfy!"
Jermaine 1-night trip
Posted 4 days ago
Holiday Inn Express & Suites Live Oak by IHG

More cheap stays in Mayo

Days Inn by Wyndham Madison

Days Inn by Wyndham Madison

6160 South State Road 53 Madison FL
The price is ￥11,593 per night from Dec 30 to Dec 31
￥11,593
￥13,042 total
Dec 30 - Dec 31
includes taxes & fees
6.8/10 (575 reviews)

Frequently asked questions

Where is the best place to stay in Mayo?
Suwannee River Rendezvous is one of the top choices for your stay based on our traveler data. This resort offers 3 outdoor pools and a restaurant. Cindys Motel is another good option for your visit. See all available top hotels, or vacation rentals in Mayo.
What are some of the best vacation home rentals in Mayo?
ICHETUCKNEE RIVER - Riverfront on the Crystal Clear Ichetucknee River: Visitors like this Mayo vacation home rental. It is located on a river and has a balcony, a garden, and a barbecue grill to put you at ease in your new surroundings. It has 4 bedrooms as well as a kitchen with a fridge, a stovetop, and a microwave, so you can cook with friends or family. See all vacation rentals in Mayo.
If I need to cancel my hotel reservation in Mayo, will I receive a refund?
Yes! Most hotel room reservations are fully refundable if you cancel before the accommodation's cancellation deadline, which is usually within 24-48 hours of your check-in date. If you booked a non-refundable reservation, you may still be able to cancel and receive a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Mayo.
Where can I learn more about changing or cancelling my trip to Mayo?
For more information about picking new dates or cancelling your trip to Mayo, click here.
What's the best pet-friendly hotel in Mayo?
Suwannee River Rendezvous is a top resort for people traveling with their pets, and offers 3 outdoor pools and free WiFi for its human guests. Cindys Motel is another option for you and your pet. See more pet-friendly hotel accommodations in Mayo.
Where is the best hotel to stay near Lafayette Blue Springs State Park?
Cindys Motel is one of the top choices for your stay based on our traveler data, and this property offers free parking and free WiFi. You'll find it 5.7 mi (9.2 km) from Lafayette Blue Springs State Park. Other good choices around the area include PEACOCK SPRINGS CAMPING!! 1 GENERATOR HOOKUP. 1 ELECTRIC HOOKUP! and Your Safari on the Suwannee River.
What are some accommodations with pools in Mayo?
Suwannee River Rendezvous: Features a snack bar/deli, 3 outdoor pools, and free self parking. Holiday Inn Express & Suites Live Oak by IHG and Best Western Plus Madison are two additional hotels that offer an onsite pool. View all hotels with pools in Mayo.
What is the best accommodation for staying close to Jacksonville International Airport (JAX)?
DoubleTree by Hilton Hotel Jacksonville Airport is a popular 3.5-star hotel featuring a restaurant and an outdoor pool. It's located a short 0.3 mi (0.5 km) from Jacksonville Intl. Airport. Other choices within close proximity to the airport include Microtel Inn & Suites by Wyndham Jacksonville Airport and Hampton Inn Suites Jacksonville Airport.
How is it to stay in Mayo?
Visitors can enjoy all that Mayo has to offer including its parks. In Mayo, there are 35 hotels and other accommodations to choose from. Find out more about Mayo.
What are the top places to visit in Mayo?
The picturesque setting of Suwannee River and Veteran's Memorial Park of Mayo exemplify the area's natural beauty. A couple of additional sights to add to your agenda are Lafayette Blue Springs State Park and Lafayette County Library. Check out what more to see and do in Expedia's Mayo guide.
What's the seasonal weather like in Mayo?
The hottest months are usually July and August with an average temp of 80°F, while the coldest months are January and February with an average of 58°F. Average annual precipitation for Mayo is 51 inches.

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