A calm river surrounded by trees with Spanish moss, reflecting the clear blue sky.

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Our top choices for Mayo hotels

Hotel
Breakfast included
Motel
Pet friendly
Resort

1. Cindys Motel

Cindys Motel
Mayo
United States
Diane
¥13,843
¥14,961 total
includes taxes & fees
Aug 10 - Aug 11
Cindys Motel

2. Suwannee River Rendezvous

Suwannee River Rendezvous
Mayo
United States
Beth
¥14,198
¥19,035 total
includes taxes & fees
Aug 12 - Aug 13
Suwannee River Rendezvous

3. Holiday Inn Express & Suites Live Oak by IHG

Holiday Inn Express & Suites Live Oak by IHG
Live Oak
United States
Trisha
¥16,565
¥18,221 total
includes taxes & fees
Aug 23 - Aug 24
Holiday Inn Express & Suites Live Oak by IHG

4. Quality Inn & Suites Live Oak I-10 Exit 283

Quality Inn & Suites Live Oak I-10 Exit 283
Live Oak
United States
Patricia
¥13,189
¥14,508 total
includes taxes & fees
Aug 19 - Aug 20
Quality Inn & Suites Live Oak I-10 Exit 283

5. Days Inn by Wyndham Madison

Days Inn by Wyndham Madison
Madison
United States
Gavin
¥11,321
¥12,735 total
includes taxes & fees
Aug 23 - Aug 24
Days Inn by Wyndham Madison

6. Econo Lodge Live Oak

Econo Lodge Live Oak
Live Oak
United States
James
¥11,540
¥12,693 total
includes taxes & fees
Aug 11 - Aug 12
Econo Lodge Live Oak

7. Best Western Plus Madison

Best Western Plus Madison
Madison
United States
Erika
¥18,773
¥21,119 total
includes taxes & fees
Aug 31 - Sep 1
Best Western Plus Madison

8. Royal Inn

Royal Inn
Live Oak
United States
rita
¥7,809
¥8,590 total
includes taxes & fees
Aug 10 - Aug 11
Royal Inn

9. Hampton Inn Perry

Hampton Inn Perry
Perry
United States
Jennifer
¥19,343
¥21,664 total
includes taxes & fees
Aug 23 - Aug 24
Hampton Inn Perry

10. Royal Inn Motel

Royal Inn Motel
Perry
United States
Alecia
¥12,463
¥13,959 total
includes taxes & fees
Aug 10 - Aug 11
Royal Inn Motel

11. Gandy Motor Lodge

Gandy Motor Lodge
Perry
United States
George
¥13,410
¥15,019 total
includes taxes & fees
Aug 10 - Aug 11
Gandy Motor Lodge

12. Super 8 by Wyndham Madison

Super 8 by Wyndham Madison
Madison
United States
Bobby
¥11,321
¥12,735 total
includes taxes & fees
Aug 23 - Aug 24
Super 8 by Wyndham Madison

13. Holiday Inn Express Hotel & Suites PERRY by IHG

Holiday Inn Express Hotel & Suites PERRY by IHG
Perry
United States
Jordan
¥23,980
¥26,858 total
includes taxes & fees
Aug 21 - Aug 22
Holiday Inn Express Hotel & Suites PERRY by IHG

14. Cross City Motel by Hotel O US 19

Cross City Motel by Hotel O US 19
Cross City
United States
Connery
¥8,519
¥10,222 total
includes taxes & fees
Aug 30 - Aug 31
Cross City Motel by Hotel O US 19

15. Good Times Motel and Marina

Good Times Motel and Marina
Steinhatchee
United States
Daniel
¥17,196
¥18,916 total
includes taxes & fees
Aug 10 - Aug 11
Good Times Motel and Marina

16. Regency Inn

Regency Inn
Perry
United States
Kevin
¥13,017
¥14,580 total
includes taxes & fees
Aug 10 - Aug 11
Regency Inn

17. Steinhatchee River Inn

Steinhatchee River Inn
Steinhatchee
United States
Kimberly
¥19,617
¥26,788 total
includes taxes & fees
Aug 24 - Aug 25
Steinhatchee River Inn

18. Carriage Inn Motel

Carriage Inn Motel
Cross City
United States
Deidra
¥11,831
¥14,750 total
includes taxes & fees
Sep 7 - Sep 8
Carriage Inn Motel

19. Putnam Lodge Hotel and Spa

Putnam Lodge Hotel and Spa
Cross City
United States
Carolyn
¥26,819
¥29,501 total
includes taxes & fees
Aug 10 - Aug 11
Putnam Lodge Hotel and Spa

20. Suwannee River Retreat: Pet Friendly, Private Dock

Suwannee River Retreat: Pet Friendly, Private Dock
Branford
¥50,799
¥95,655 total
includes taxes & fees
Aug 18 - Aug 19
Suwannee River Retreat: Pet Friendly, Private Dock
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Stay near popular Mayo attractions

Lafayette Blue Springs State Park

8.0/10 (6 reviews)
Dive into this first-magnitude spring's crystal-clear waters flowing beneath a natural limestone bridge. Explore underwater caves or paddle to the iconic Suwannee River amid moss-draped oaks.
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Perry Spring

Perry Spring offers crystal-clear 72-degree waters where you can swim from a jumping platform into the Suwannee River. Relax at the covered pavilion with fire pit or lounge on the river deck with floating dock.
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Lafayette County Library

This welcoming community hub offers books, e-books, and resources for all ages. Enjoy free Wi-Fi, participate in book clubs, or attend special seasonal programs that promote literacy and community engagement.
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Allen Mill Pond Spring

This historic second-magnitude spring flows crystal-clear over ancient limestone beneath a canopy of cypress trees. Winter visits offer the best views of the old mill remnants when vegetation thins.
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Veteran's Memorial Park of Mayo

This peaceful memorial park honors veterans with thoughtful monuments and landscaped grounds. Visitors can reflect on service and sacrifice while enjoying the serene atmosphere.
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Learn more about Mayo

Paddle through crystal-clear waters at Lafayette Blue Springs State Park where swimming and snorkeling reveal underwater caves and limestone formations. Explore the peaceful Suwannee River by kayak or visit Perry Spring, where locals gather for refreshing dips during hot summer afternoons.

See all hotels in Mayo
A calm river surrounded by trees reflecting in the water.

Top Mayo Hotel Reviews

Good Times Motel and Marina

Good Times Motel and Marina

10/10 Excellent
"Staff are amazing. They take care of any needs you may have. This is my 5th visit. Cabin 3 is my favorite. It has an oven and I can see my boat in the slip. Its right by the dock."
Chad 4-night trip
Posted 16 hours ago
Good Times Motel and Marina
Best Western Plus Madison

Best Western Plus Madison

10/10 Excellent
"My 3 night stay was great. Breakfast staff were great. With exception of not being told you must request room service and laundry equipment not working."
Deveta 3-night trip
Posted 21 hours ago
Best Western Plus Madison
Super 8 by Wyndham Madison

Super 8 by Wyndham Madison

8/10 Good
"there was light coming in through the edges of the door, need more insulation"
Errol 2-night trip
Posted 1 day ago
Super 8 by Wyndham Madison
Holiday Inn Express & Suites Live Oak by IHG

Holiday Inn Express & Suites Live Oak by IHG

10/10 Excellent
"The rate per night was reasonable, the breakfast was amazing, and unlimited free coffee was prefect, and the staff was very helpful and accommodating when we had an issue after the rain."
Trisha 2-night trip
Posted 6 days ago
Holiday Inn Express & Suites Live Oak by IHG
Friendly's river retreat #1 cozy couples cabin in awesome Mayo with WiFi,

Friendly's river retreat #1 cozy couples cabin in awesome Mayo with WiFi,

10/10 Excellent
"We had a fantastic time! Perfect for couples, less than 15 min drive from Lafayette Blue Springs and less than 30 from Madison Blue Springs. Cabin had everything we needed. The perfect rural Florida gettaway, we plan to come back and stay again next year!"
Molly 3-night trip
Posted 12 days ago
Friendly's river retreat #1 cozy couples cabin in awesome Mayo with WiFi,
Putnam Lodge Hotel and Spa

Putnam Lodge Hotel and Spa

10/10 Excellent
"This place is like stepping back into history. You will love it."
Carolyn 1-night trip
Posted 13 days ago
Putnam Lodge Hotel and Spa
Regency Inn

Regency Inn

8/10 Good
"It is good for a one-night... passing thru type stay. Room was crowded with oversized and unneeded furniture."
Kevin 1-night trip
Posted 2 weeks ago
Regency Inn
Friendlys River Retreat private 
Rustic Camping Cabin sleeps 4+with tent camping

Friendlys River Retreat private Rustic Camping Cabin sleeps 4+with tent camping

10/10 Excellent
"Very peaceful and quiet. The host was very friendly and helpful. The room was clean. I really enjoyed the stay. A lot of springs near by to swim in. Will be staying there again."
Richard 2-night trip
Posted 1 month ago
Friendlys River Retreat private Rustic Camping Cabin sleeps 4+with tent camping
Lake Retreat of Steinhatchee- bring your RV to the place for fun and memories!!

Lake Retreat of Steinhatchee- bring your RV to the place for fun and memories!!

10/10 Excellent
"It's a little tight for larger RVs"
Melissa T. 4-night trip
Posted 2 months ago
Lake Retreat of Steinhatchee- bring your RV to the place for fun and memories!!

More cheap stays in Mayo

Days Inn by Wyndham Madison

Days Inn by Wyndham Madison

6160 South State Road 53 Madison FL
¥11,321
¥12,735 total
Aug 23 - Aug 24
includes taxes & fees
Days Inn by Wyndham Madison
Quality Inn & Suites Live Oak I-10 Exit 283

Quality Inn & Suites Live Oak I-10 Exit 283

6819 Us Highway 129 Live Oak FL
¥13,189
¥14,508 total
Aug 19 - Aug 20
includes taxes & fees
7/10 Good! (581 reviews)
Quality Inn & Suites Live Oak I-10 Exit 283
Holiday Inn Express & Suites Live Oak by IHG

Holiday Inn Express & Suites Live Oak by IHG

6694 Us Highway 129 Live Oak FL
¥16,565
¥18,221 total
Aug 23 - Aug 24
includes taxes & fees
8.4/10 Very Good! (863 reviews)
Holiday Inn Express & Suites Live Oak by IHG
Good Times Motel and Marina

Good Times Motel and Marina

7022 SW Hwy 358 Steinhatchee FL
¥17,196
¥18,916 total
Aug 10 - Aug 11
includes taxes & fees
9.4/10 Exceptional! (191 reviews)
Good Times Motel and Marina
Best Western Plus Madison

Best Western Plus Madison

167 SE Bandit Street Madison FL
¥18,773
¥21,119 total
Aug 31 - Sep 1
includes taxes & fees
8/10 Very Good! (628 reviews)
Best Western Plus Madison
Holiday Inn Express Hotel & Suites PERRY by IHG

Holiday Inn Express Hotel & Suites PERRY by IHG

601 Everett Way Perry FL
¥23,980
¥26,858 total
Aug 21 - Aug 22
includes taxes & fees
Holiday Inn Express Hotel & Suites PERRY by IHG

Find out more about Mayo

Top reasons to visit Mayo

  • Outdoor Adventures: Mayo offers a variety of activities such as hiking, fishing, and scuba diving for adventure enthusiasts.
  • Scenic Beauty: The town is surrounded by stunning natural landscapes, perfect for relaxation and exploration.
  • Family-Friendly Activities: Mayo provides a welcoming atmosphere with attractions suitable for families of all sizes.
  • Local Hospitality: Enjoy cozy accommodations and friendly service that reflect the town's community spirit.
  • Recreational Areas: Explore beautiful rivers and state parks that highlight Mayo's outdoor charm.

Find great hotels near Mayo

Discover the charm of Mayo, Florida, where a variety of hotel accommodations await to make your stay memorable. Whether you’re seeking pet-friendly options or a cozy motel for your adventure-filled vacation, Mayo has something for every traveler. Enjoy convenient amenities tailored for business travelers and leisure seekers alike. Explore the local hospitality that captures the essence of this quaint town while providing a comfortable retreat during your visit.

  • Holiday Inn Express & Suites Live Oak by IHG: Located about 37km from Mayo, the Holiday Inn Express & Suites offers a contemporary and comfortable setting for business travelers. With a guest rating of 8.4 out of 10, this budget-friendly hotel features modern rooms equipped with free Wi-Fi, a fitness center, and a complimentary breakfast bar to kickstart your day. The hotel’s business amenities include a meeting room and a 24-hour business center, making it an ideal choice for those needing to blend work and leisure. Guests have appreciated the friendly staff and convenient location, ensuring a hassle-free stay.
  • Royal Inn Motel: Situated approximately 40km from Mayo, the Royal Inn Motel boasts a guest rating of 8.8 out of 10, highlighting its appeal as a cozy and budget-friendly lodging option. The motel offers essential amenities including Cable TV and LCD TVs in each room, providing a comfortable atmosphere for relaxation. Known for its cleanliness and attentive service, the Royal Inn is perfect for travelers seeking a simple yet enjoyable stay. The property’s proximity to local attractions and dining options enhances its appeal, ensuring guests have everything they need within reach.
  • Quality Inn & Suites Live Oak I-10 Exit 283: Located just 35km from Mayo, the Quality Inn & Suites is a versatile lodging choice that caters to both business and pet-friendly travelers. This budget-friendly hotel offers a rating of 8.4 out of 10 and features spacious rooms alongside essential amenities. Guests can enjoy complimentary breakfast and a fitness center, while pet owners will appreciate the accommodating pet policies allowing for a more inclusive experience. The hotel’s strategic location near I-10 makes it convenient for exploring the area, making it a great base for your travels.

Where to stay in and around Mayo

Mayo, Florida, is a hidden gem for outdoor enthusiasts and adventure seekers. Nestled amidst stunning natural scenery, it offers a range of activities from hiking and fishing to exploring nearby rivers and parks. The charm of this small town lies in its welcoming atmosphere, making it perfect for family vacations. Don't miss the chance to experience Mayo's unique blend of nature and community spirit, ensuring a memorable getaway in the heart of Florida.

  • O Brien: O Brien is a charming city located 23km from Mayo, offering a blend of outdoor adventures and scenic beauty. The area experiences moderate seasonal visitor traffic, peaking during the summer months from June to August. Travelers flock to O Brien for its numerous outdoor activities, including recreational areas for hiking and adventure sports. You'll find a stunning river and a national state park nearby, perfect for exploration. Whether you're interested in underwater sports or simply soaking in the beautiful surroundings, O Brien provides a perfect getaway for adventure enthusiasts.
  • Day: Nestled within the Mayo area, Day is a quaint village that attracts visitors year-round, with peak times in March and from June to July. It’s an ideal destination for families seeking beach experiences and outdoor fun. The village offers access to beautiful family-friendly beaches, parks, and various recreational areas perfect for relaxation and adventure. Whether you're looking to enjoy a day by the water or participate in exciting outdoor activities, Day has something for everyone, making it a delightful stop on your vacation.
  • Dowling Park: Located 23km from Mayo, Dowling Park is a picturesque village that sees highly seasonal visitors, particularly in April, July, and September. It's renowned for its outdoor adventures and stunning scenery. The area boasts a range of recreational opportunities, including an amusement park that caters to thrill-seekers and families alike. Nearby attractions such as a tranquil river, a national state park, and a beautiful lake provide ample opportunities for exploration and relaxation. Dowling Park is perfect for those looking to immerse themselves in nature and enjoy a variety of outdoor activities.

Things to do in Mayo

Shopping

Mayo offers a charming shopping experience with local boutiques and gift shops for unique souvenirs. If you're up for a drive, head to the nearby Lake City Mall, about 48km away, featuring a variety of stores and dining options for a more extensive shopping trip.

Recreation

In Mayo, the Suwannee River State Park offers a peaceful retreat with scenic trails for hiking and birdwatching. Nearby, the Mayo Wellness Center provides yoga classes and wellness workshops, promoting relaxation and mindfulness in a tranquil environment surrounded by nature.

Adventure

Explore the pristine waters of the Suwannee River with kayaking or canoeing adventures, offering stunning views of untouched nature and wildlife. For hiking enthusiasts, the nearby Big Shoals State Park features challenging trails and picturesque landscapes, perfect for an adventurous day outdoors.

Nightlife

Mayo offers a laid-back nightlife vibe, with local bars like The Brickhouse and The Swamp where you can unwind with friends. Enjoy live music and dancing at The Gathering, or savor a late-night meal at nearby diners for a taste of Southern hospitality.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Find the best attractions in and around Mayo

Mayo, Florida, is perfect for outdoor enthusiasts and adventure seekers, offering beautiful scenery and family-friendly experiences. Key attractions include rivers, state parks, and the local library. Visitors can explore the Mayo Center and enjoy various outdoor activities that highlight the area's natural beauty. Whether you're seeking relaxation or adventure, Mayo has something to offer for everyone.

  • Lafayette Blue Springs State Park: This beautiful park offers stunning natural scenery and a variety of outdoor adventures. Visitors can enjoy swimming in the clear blue springs, hiking through scenic trails, or picnicking in shaded areas, making it a great spot for nature lovers and outdoor enthusiasts.
  • Lafayette County Library: A hub of culture and learning, this library provides a welcoming atmosphere for families. Visitors can explore a diverse collection of books, attend community events, and engage in various programs that promote literacy and cultural appreciation.
  • Suwannee River: Located 26km from Mayo, the Suwannee River offers picturesque views and opportunities for outdoor activities such as kayaking and fishing. Its tranquil waters are perfect for a relaxing day surrounded by nature.

Best time to go to Mayo

The best time to visit Mayo can depend on the weather and when visitor numbers rise and fall. The hottest average temperature in Mayo falls in July, when visitor numbers are average and weather is mostly sunny with light rain. The coolest average temperature in Mayo falls in January, visitor numbers are average and weather is mostly sunny with light rain.

calendar iconCalendar Monthtemperature iconTemperaturerain iconPrecipitationmostly cloudy iconCloudinessoccupation rate iconOccupancyprice iconPricing
January53.4°F (11.9°C)Light RainMostly SunnyAverageSlightly Low
February57.9°F (14.4°C)Light RainMostly SunnySlightly LowSlightly Low
March62.8°F (17.1°C)Light RainMostly SunnySlightly HighAverage
April69.1°F (20.6°C)Light RainMostly SunnySlightly HighAverage
May75.4°F (24.1°C)Light RainMostly SunnyAverageAverage
June80.2°F (26.8°C)Light RainMostly SunnyAverageSlightly High
July81.5°F (27.5°C)Light RainMostly SunnyAverageSlightly High
August81.3°F (27.4°C)Light RainMostly SunnySlightly LowSlightly High
September77.9°F (25.5°C)Light RainMostly SunnySlightly HighAverage
October70.9°F (21.6°C)No RainMostly SunnyAverageAverage
November61.9°F (16.6°C)Light RainMostly SunnyAverageAverage
December57.4°F (14.1°C)Light RainMostly SunnySlightly LowSlightly Low

The nearest major airports for your trip to Mayo

Traveling to Mayo, Florida, is convenient with several nearby airports. Jacksonville International Airport (JAX) is located 151km away, with excellent hotel options like the 4-star Hyatt Regency Jacksonville and DoubleTree by Hilton, both 19km from the airport. Tallahassee International Airport (TLH) is only 119km away, offering nearby accommodations such as the 4-star DoubleTree by Hilton and Hotel Duval, both just 8km from TLH. Gainesville Regional Airport (GNV) is 95km from Mayo, with options including the 4-star DoubleTree by Hilton Gainesville, located 13km from the airport. Each hotel provides various transportation services to their respective airports.

Frequently asked questions

Where is the best place to stay in Mayo?
Suwannee River Rendezvous is one of the top choices for your stay based on our traveler data. This resort offers 3 outdoor pools and a restaurant. Cindys Motel is another good option for your visit. See all available top hotels, or vacation rentals in Mayo.
What are some of the best vacation home rentals in Mayo?
ICHETUCKNEE RIVER - Riverfront on the Crystal Clear Ichetucknee River: You might want to consider this vacation home rental near Mayo, which is located on a river and has a balcony, a garden, and a barbecue grill to put you at ease in your new surroundings. It has 4 bedrooms as well as a kitchen with a fridge, a stovetop, and a microwave, so you can cook with friends or family. See all vacation rentals in Mayo.
If I need to cancel my hotel reservation in Mayo, will I receive a refund?
Yes! Most hotel room reservations are fully refundable if you cancel before the accommodation's cancellation deadline, which is usually within 24-48 hours of your check-in date. If you booked a non-refundable reservation, you may still be able to cancel and receive a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Mayo.
Where can I learn more about changing or cancelling my trip to Mayo?
For more information about picking new dates or cancelling your trip to Mayo, click here.
What's the best pet-friendly hotel in Mayo?
Suwannee River Rendezvous is a top resort for people traveling with their pets, and offers 3 outdoor pools and free WiFi for its human guests. Cindys Motel is another option for you and your pet. See more pet-friendly hotel accommodations in Mayo.
Where is the best hotel to stay near Lafayette Blue Springs State Park?
Cindys Motel is one of the top choices for your stay based on our traveler data, and this property offers free parking and free WiFi. You'll find it 5.7 mi (9.2 km) from Lafayette Blue Springs State Park. Other good choices around the area include PEACOCK SPRINGS CAMPING!! 1 GENERATOR HOOKUP. 1 ELECTRIC HOOKUP! and Your Safari on the Suwannee River.
What are some accommodations with pools in Mayo?
Suwannee River Rendezvous: Features a snack bar/deli, 3 outdoor pools, and free self parking. Holiday Inn Express & Suites Live Oak by IHG and Holiday Inn Express Hotel & Suites PERRY by IHG are two additional hotels that offer an onsite pool. View all hotels with pools in Mayo.
What is the best accommodation for staying close to Jacksonville International Airport (JAX)?
DoubleTree by Hilton Hotel Jacksonville Airport is a popular 3.5-star hotel featuring a restaurant and an outdoor pool. It's located a short 0.3 mi (0.5 km) from Jacksonville Intl. Airport. Other choices within close proximity to the airport include Microtel Inn & Suites by Wyndham Jacksonville Airport and Hampton Inn Suites Jacksonville Airport.
How is it to stay in Mayo?
Visitors can enjoy all that Mayo has to offer including its parks. In Mayo, there are 35 hotels and other accommodations to choose from. Find out more about Mayo.
What are the top places to visit in Mayo?
The picturesque setting of Suwannee River and Veteran's Memorial Park of Mayo exemplify the area's natural beauty. A couple of additional sights to add to your agenda are Lafayette Blue Springs State Park and Lafayette County Library. Check out what more to see and do in Expedia's Mayo guide.
What's the seasonal weather like in Mayo?
The hottest months are usually July and August with an average temp of 80°F, while the coldest months are January and February with an average of 58°F. Average annual precipitation for Mayo is 51 inches.

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