Find hotels in Jeff-Vander-Lou, St. Louis from ¥10,905
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Discover 1,774 Jeff-Vander-Lou hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.
Our top choices for Jeff-Vander-Lou hotels

The West End
The West End

Residence Inn By Marriott St. Louis Clayton
Residence Inn By Marriott St. Louis Clayton

Holiday Inn Express and Suites Alton St Louis Area by IHG
Holiday Inn Express and Suites Alton St Louis Area by IHG

Guest Host Motel
Guest Host Motel

Motel 6 Troy, IL
Motel 6 Troy, IL

21C Museum Hotel St Louis
21C Museum Hotel St Louis
Where to stay in Jeff-Vander-Lou

Downtown St. Louis
Head to the heart of the largest city in Missouri for its cultural hotspots, nightlife and a colossal monument that towers over the Mississippi River.

Clayton
Visitors often come to Clayton for its abundant dining options, but many stay to explore sights like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. Getting around the area on the metro is easy if you catch a ride at Clayton Station.

Central West End
Bordering Forest Park with free cultural institutions, this St. Louis neighborhood boasts a bustling commercial district along Euclid Avenue and the world's largest mosaic collection at the Cathedral Basilica of Saint Louis.
Creve Coeur
Creve Coeur is known for its abundant dining options, and you can plan a trip to Creve Coeur Golf Club and Saint Louis Abbey while you're in town.

Downtown West
If you're spending some time in Downtown West, St. Louis Union Station and St. Louis Aquarium at Union Station are top sights worth seeing.
Top Jeff-Vander-Lou Hotel Reviews

Clayton Plaza Hotel & Extended Stay
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