A densely packed urban area with a central plaza surrounded by buildings with red-tiled roofs.

Find hotels in El Santuario from ¥4,472

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Check prices for these dates

Tonight
Aug 13 - Aug 14
Tomorrow
Aug 14 - Aug 15
This weekend
Aug 14 - Aug 16
Next weekend
Aug 21 - Aug 23

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Our top choices for El Santuario hotels

Breakfast included
Hotel
Reserve now, pay later
Pet friendly
Pool

1. MONTANA ECO HOTEL

MONTANA ECO HOTEL
El Santuario
¥23,379
¥23,379 total
Aug 17 - Aug 18
MONTANA ECO HOTEL

2. Casa Rose Hotel

Casa Rose Hotel
El Carmen de Viboral
United States
Alfredo
¥13,443
¥13,443 total
Aug 28 - Aug 29
Casa Rose Hotel

3. Porto Marina Hotel

Porto Marina Hotel
El Penol
United States
Gustavo
¥13,198
¥13,198 total
Sep 13 - Sep 14
Porto Marina Hotel

4. Isak Hotel & Golf Airport

Isak Hotel & Golf Airport
Rionegro
United States
Alejandra
¥16,049
¥16,049 total
Aug 14 - Aug 15
Isak Hotel & Golf Airport

5. Hotel Chromatic

Hotel Chromatic
Guatapé
United States
Joshua
¥7,726
¥8,487 total
Aug 24 - Aug 25
Hotel Chromatic

6. NEW STAR CENTER

NEW STAR CENTER
Rionegro
United States
Lucia
¥8,810
¥8,810 total
Aug 19 - Aug 20
NEW STAR CENTER

7. Hotel Santamaria INN

Hotel Santamaria INN
La Ceja
United States
Pablo
¥5,273
¥8,822 total
Sep 4 - Sep 5
Hotel Santamaria INN

8. Hotel Los Recuerdos

Hotel Los Recuerdos
Guatapé
United States
Ryan
¥17,426
¥17,426 total
Aug 14 - Aug 15
Hotel Los Recuerdos

9. Hotel Santiago de Arma

Hotel Santiago de Arma
Rionegro
United States
JOHN Kirby
¥20,991
¥20,991 total
Sep 13 - Sep 14
Hotel Santiago de Arma

10. Autenthico Sajonia Hotel Aeropuerto

Autenthico Sajonia Hotel Aeropuerto
Rionegro
United States
Cristian
¥9,779
¥9,779 total
Aug 31 - Sep 1
Autenthico Sajonia Hotel Aeropuerto

11. MYLOS Hotel Boutique

MYLOS Hotel Boutique
Guatapé
United Kingdom
neil
¥34,988
¥34,988 total
Aug 17 - Aug 18
MYLOS Hotel Boutique

12. Hotel Lagoon

Hotel Lagoon
Rionegro
United States
Bianca
¥23,238
¥23,238 total
Sep 9 - Sep 10
Hotel Lagoon

13. Hotel Santorini

Hotel Santorini
Guatapé
United States
Stephen
¥13,438
¥13,438 total
Aug 14 - Aug 15
Hotel Santorini

14. Travelers Rio Verde Living Suites

Travelers Rio Verde Living Suites
Rionegro
United States
Christian
¥14,550
¥14,550 total
Aug 14 - Aug 15
Travelers Rio Verde Living Suites

15. EL NIDO HOTEL GUATAPE

EL NIDO HOTEL GUATAPE
Guatapé
United States
EDGAR
¥22,644
¥22,644 total
Aug 18 - Aug 19
EL NIDO HOTEL GUATAPE

16. Soy Local Reserva Sajonia

Soy Local Reserva Sajonia
Rionegro
United States
Christian
¥12,410
¥12,410 total
Aug 24 - Aug 25
Soy Local Reserva Sajonia

17. Movich Hotel Las Lomas

Movich Hotel Las Lomas
Rionegro
United States
abigail
¥23,078
¥23,078 total
Sep 13 - Sep 14
Movich Hotel Las Lomas

18. Luxé Cabañas

Luxé Cabañas
Guatapé
United States
Keila Marie
¥53,006
¥53,006 total
Aug 19 - Aug 20
Luxé Cabañas

19. Lleras Express

Lleras Express
El Poblado
United States
Víctor Gregorio
¥7,105
¥7,105 total
Aug 17 - Aug 18
Lleras Express

20. Hashtag 98 Hotel By Jalo

Hashtag 98 Hotel By Jalo
El Poblado
United States
Juan
¥10,870
¥10,870 total
Aug 25 - Aug 26
Hashtag 98 Hotel By Jalo
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Learn more about El Santuario

Head to Comfama Tutucán Recreational Park and Rock of Guatapé—just two of the sights around El Santuario.

See all hotels in El Santuario
A densely packed urban area with a central plaza surrounded by buildings with red-tiled roofs.

Top El Santuario Hotel Reviews

V Grand Hotel, a member of Radisson Individuals

V Grand Hotel, a member of Radisson Individuals

8/10 Good
"Que tengan más variedad en el desayuno"
Zulay 3-night trip
Posted 3 hours ago
V Grand Hotel, a member of Radisson Individuals
Hunters Hotel Medellín

Hunters Hotel Medellín

10/10 Excellent
"Have to give 2 keys because if one of them went out the room after you take the key out all room turn off lights. TV. And air conditioner."
Katty 4-night trip
Posted 4 hours ago
Hunters Hotel Medellín
Heiss Hotel By Jalo

Heiss Hotel By Jalo

10/10 Excellent
"I absolutely loved everything here!"
Eddie 7-night trip
Posted 17 hours ago
Heiss Hotel By Jalo
The Click Clack Hotel Medellin

The Click Clack Hotel Medellin

10/10 Excellent
"This hotel is very unique. Everything is designed for perfection and service is not just a word. Truly amazing hotel and staff ❤️"
Tomer 2-night trip
Posted 18 hours ago
The Click Clack Hotel Medellin
Novotel Medellín El Tesoro

Novotel Medellín El Tesoro

10/10 Excellent
"It’s My home. They are my family. Amazing place"
Juan Carlos 14-night trip
Posted 19 hours ago
Novotel Medellín El Tesoro
Hotel Park 10

Hotel Park 10

10/10 Excellent
"El Hotel ideal. Es elegante y a nosotros nos incluyo el desayuno, muy bueno. Esta cerca de todo pero es silenciosos y privado. Lo recomiendo 100%"
Isabel 4-night trip
Posted 20 hours ago
Hotel Park 10
The Charlee Hotel

The Charlee Hotel

10/10 Excellent
"Wonderful Stay & Exceptional Service ⭐️⭐️⭐️⭐️⭐️ My group and I had a wonderful stay at The Charlee Hotel. The hotel has a great atmosphere, and what truly elevated our experience was the exceptional service from the entire team — warm, professional, attentive, and genuinely welcoming. A special thank you to Anderson at reception, who looked after me beautifully from the moment I arrived. I was waiting for my group of 14 friends whose flight had been delayed, and Anderson was incredibly kind, helpful, and attentive throughout. His service was exceptional. Santiago was equally outstanding. When our group of 15 departed with around 30 suitcases, he went above and beyond to help the driver load everything into the van, all while maintaining a wonderful smile and positive attitude. Truly first-class service. A big thank you as well to the evening security team, who looked after us while we waited outside for transportation and helped keep unwanted street vendors and solicitors at bay. We really appreciated their care and professionalism. The only minor improvements would be adding sun loungers around the pool and speeding up the egg service at breakfast, which could sometimes take 15–20 minutes. Overall, a fantastic experience. Thank you to the entire Charlee team — especially Anderson, Santiago, and the evening security staff — for making our stay so memorable"
Olivia 6-night trip
Posted 23 hours ago
The Charlee Hotel
Hotel San Fernando Plaza

Hotel San Fernando Plaza

10/10 Excellent
"El personal muy querido, el hotel limpio y en buen estado, el desayuno bueno."
Sofia 17-night trip
Posted 1 day ago
Hotel San Fernando Plaza

More cheap stays in El Santuario

Hostal Lleras Calle 8 - Hostel

Hostal Lleras Calle 8 - Hostel

Calle 8 # 37A - 59 Medellín Antioquia
¥4,472
¥4,472 total
Sep 13 - Sep 14
8.4/10 Very Good! (155 reviews)
Hostal Lleras Calle 8 - Hostel
Fresco Provenza Living - Musical lifestyle

Fresco Provenza Living - Musical lifestyle

Carrera 36 # 7 -32 Medellín Antioquia
¥5,828
¥5,828 total
Aug 23 - Aug 24
9.4/10 Exceptional! (8 reviews)
Fresco Provenza Living - Musical lifestyle
Autenthico Sajonia Hotel Aeropuerto

Autenthico Sajonia Hotel Aeropuerto

Aeropuerto Jose Maria Cordova, Km 20 Rionegro Antioquia
¥9,779
¥9,779 total
Aug 31 - Sep 1
9.2/10 Wonderful! (89 reviews)
Autenthico Sajonia Hotel Aeropuerto
Nakúa Stay + Work

Nakúa Stay + Work

8A-29 Cra. 34 Medellín Antioquia
¥11,493
¥11,493 total
Aug 19 - Aug 20
Nakúa Stay + Work
Soy Local Reserva Sajonia

Soy Local Reserva Sajonia

Variante las palmas Rionegro Antioquia
¥12,410
¥12,410 total
Aug 24 - Aug 25
Soy Local Reserva Sajonia
Masaya Medellin

Masaya Medellin

43a1 Cl. 8 Medellín Antioquia
¥12,641
¥12,641 total
Sep 6 - Sep 7
Masaya Medellin

Frequently asked questions

Where is the best place to stay in El Santuario?
Located 22.1 mi (35.5 km) from the heart of El Santuario, Heiss Hotel By Jalo is a top choice for your stay based on our traveler data. Other good choices for your visit to the area are Calle Flora Hotel by Jalo and Hashtag 98 Hotel By Jalo. See all available top hotels, or vacation rentals in El Santuario.
What's the top vacation rental that El Santuario has to offer?
8 BR Luxury 6000 S.F. Mansion , 2 Bars Hot Tub, Bbq and Ac: This vacation home rental outside of El Santuario offers a patio, a pool table, and a barbecue grill to help you feel perfectly comfortable in your new surroundings. It has 8 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. You and your friends and family can relax into your vacation with amenities like a hot tub. See all vacation rentals in El Santuario.
If I need to cancel my hotel reservation in El Santuario, will I receive a refund?
Yes, most room reservations are fully refundable if cancelled before the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your arrival date. If you booked a non-refundable reservation, you might still have the option to cancel and get a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in El Santuario.
Where can I learn more about changing or cancelling my trip to El Santuario?
To access more information about updating your trip to El Santuario or cancelling it, click here.
What's it like staying in El Santuario?
Visitors are sure to enjoy all that El Santuario has to offer. In El Santuario, there are 2 hotels and other accommodations to choose from. Find out more about El Santuario.
What are the top places to visit in El Santuario?
Places to visit in the wider area include San Nicolás Mall, Comfama Tutucán Recreational Park, and Rock of Guatapé. You'll also find Piedra del Marial and Llanogrande Mall in the area. Check out what more to see and do in Expedia's El Santuario guide.
What's the seasonal weather like in El Santuario?
The hottest months are usually August and September with an average temp of 63°F, while the coldest months are January and July with an average of 63°F. The rainiest months in El Santuario are April, May, October, and November, with each month seeing an average of 17 inches of rainfall.

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