A densely packed urban area with a central plaza surrounded by buildings with red-tiled roofs.

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Sep 4 - Sep 5
Tomorrow
Sep 5 - Sep 6
This weekend
Sep 4 - Sep 6
Next weekend
Sep 11 - Sep 13

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Our top choices for El Santuario hotels

1. MONTANA ECO HOTEL

MONTANA ECO HOTEL
El Santuario
¥22,111
¥22,111 total
Sep 6 - Sep 7
MONTANA ECO HOTEL

2. Casa Rose Hotel

Casa Rose Hotel
El Carmen de Viboral
United States
Fabio
¥12,245
¥12,245 total
Oct 5 - Oct 6
Casa Rose Hotel

3. Alfahar Hotel

Alfahar Hotel
El Carmen de Viboral
United States
Diana
¥18,236
¥18,236 total
Sep 20 - Sep 21
Alfahar Hotel

4. Isak Hotel & Golf Airport

Isak Hotel & Golf Airport
Rionegro
United States
John
¥16,844
¥16,844 total
Sep 5 - Sep 6
Isak Hotel & Golf Airport

5. NEW STAR CENTER

NEW STAR CENTER
Rionegro
United States
Lucia
¥9,815
¥9,815 total
Sep 6 - Sep 7
NEW STAR CENTER

6. Porto Marina Hotel

Porto Marina Hotel
El Penol
United States
Fabian
¥12,855
¥12,855 total
Oct 5 - Oct 6
Porto Marina Hotel

7. Autenthico Sajonia Hotel Aeropuerto

Autenthico Sajonia Hotel Aeropuerto
Rionegro
United States
Divya
¥9,779
¥9,779 total
Sep 28 - Sep 29
Autenthico Sajonia Hotel Aeropuerto

8. Bahia Serena Hotel

Bahia Serena Hotel
Guatape
Peru
Cristian
¥11,474
¥11,474 total
Sep 8 - Sep 9
Bahia Serena Hotel

9. La Martina Campestre

La Martina Campestre
Rionegro
United States
David
¥9,019
¥9,019 total
Sep 7 - Sep 8
La Martina Campestre

10. Soy Local Reserva Sajonia

Soy Local Reserva Sajonia
Rionegro
United States
Christian
¥10,637
¥10,637 total
Sep 6 - Sep 7
Soy Local Reserva Sajonia

11. Hotel Los Recuerdos

Hotel Los Recuerdos
Guatapé
United States
Jason
¥17,125
¥17,125 total
Oct 5 - Oct 6
Hotel Los Recuerdos

12. Hotel Santiago de Arma

Hotel Santiago de Arma
Rionegro
United States
Mario
¥19,712
¥19,712 total
Sep 5 - Sep 6
Hotel Santiago de Arma

13. Hotel Velero

Hotel Velero
Rionegro
¥20,362
¥20,362 total
Sep 16 - Sep 17
Hotel Velero

14. Hotel Lagoon

Hotel Lagoon
Rionegro
United States
Omaria
¥22,762
¥22,762 total
Sep 7 - Sep 8
Hotel Lagoon

15. MYLOS Hotel Boutique

MYLOS Hotel Boutique
Guatapé
United States
Martin
¥32,049
¥32,049 total
Sep 8 - Sep 9
MYLOS Hotel Boutique

16. Travelers Rio Verde Living Suites

Travelers Rio Verde Living Suites
Rionegro
United States
Humberto
¥16,462
¥16,462 total
Sep 7 - Sep 8
Travelers Rio Verde Living Suites

17. EL NIDO HOTEL GUATAPE

EL NIDO HOTEL GUATAPE
Guatapé
United States
JAVIER
¥27,436
¥27,436 total
Sep 5 - Sep 6
EL NIDO HOTEL GUATAPE

18. Luxé Cabañas

Luxé Cabañas
Guatapé
United States
Michael
¥51,920
¥51,920 total
Sep 7 - Sep 8
Luxé Cabañas

19. Movich Hotel Las Lomas

Movich Hotel Las Lomas
Rionegro
United States
Anuradha
¥22,074
¥22,074 total
Oct 4 - Oct 5
Movich Hotel Las Lomas

20. Lleras Green Hotel

Lleras Green Hotel
El Poblado
United States
Ronald
¥7,123
¥7,123 total
Sep 10 - Sep 11
Lleras Green Hotel
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Learn more about El Santuario

Head to Comfama Tutucán Recreational Park and Rock of Guatapé—just two of the sights around El Santuario.

See all hotels in El Santuario
A densely packed urban area with a central plaza surrounded by buildings with red-tiled roofs.

Top El Santuario Hotel Reviews

Calle Flora Hotel by Jalo

Calle Flora Hotel by Jalo

8/10 Good
"The room was clean and comfortable. I didn’t have a problem with the noise from the streets because the rooms were equipped with earplugs. My major issue with this hotel was there was no room service. At one point we wanted ice and could not get ice. We went to the front desk to ask for ice and were told that we can go and ask the nearby stores or bars or nightclubs for ice. The breakfast served was the exact same thing every day. When we were preparing to leave for our early flight, Breakfast was already set up, but it was not 7 AM as yet and we try to get a cup of coffee and was denied. All in all the hotel location was perfect, right in the middle of everything"
Shevon 5-night trip
Posted 9 hours ago
Calle Flora Hotel by Jalo
Hotel Provenza Garden

Hotel Provenza Garden

10/10 Excellent
"Los empleados de el caunter son unas odiosa"
Alexandra Marrero 3-night trip
Posted 11 hours ago
Hotel Provenza Garden
Hunters Hotel Medellín

Hunters Hotel Medellín

10/10 Excellent
"Súper céntrico, todo limpio y ordenado. Muy accesible"
Jose 7-night trip
Posted 13 hours ago
Hunters Hotel Medellín
Selvario 36 Hotel

Selvario 36 Hotel

8/10 Good
"Selvario 36 is a stunning and highly original hotel, with beautiful design and thoughtful details throughout. The staff were also incredibly helpful, welcoming, and attentive. There were, however, two disappointments. First, the room lacked a proper closet. Instead, there was a wooden bar extending from the wall to hang clothes, but without a stopper, clothes constantly slid off. My biggest surprise was the rooftop pricing. On our first night, our party ordered four imported sparkling waters with lemon juice and were shocked to discover the bill was 169,352 Colombian pesos—approximately CAD$74. We were told the water was imported but not informed of the price beforehand. Ironically, alcohol would have been cheaper. To add insult to injury, we later discovered the hotel makes its own sparkling water, which is offered complimentary to guests. Overall, a beautiful and memorable hotel with wonderful staff, but a little more practicality in the rooms and transparency around pricing would make the experience even better."
Vasiliki 3-night trip
Posted 17 hours ago
Selvario 36 Hotel
The Click Clack Hotel Medellin

The Click Clack Hotel Medellin

10/10 Excellent
"I loved the stay in my hotel. By far one of the best experiences. But this one is amazing. Staff were amazing. I loved the rooftop bar and Alexander the security guard in the early day time. I’m going to Medellín again in early 2026 and will try to book with click clack again but the price was just a bit too high so I might go with another hotel. Their food was spectacular as well as the views! Even if I don’t go back as a hotel guest I’ll go back for their ceviche!"
Rennard 7-night trip
Posted 1 day ago
The Click Clack Hotel Medellin
Hotel San Fernando Plaza

Hotel San Fernando Plaza

10/10 Excellent
"El hotel esta super bien ubicado y l atención es maravillosa todo el personal es muy atento , me encanto volvería"
Marcela 3-night trip
Posted 1 day ago
Hotel San Fernando Plaza
Heiss Hotel By Jalo

Heiss Hotel By Jalo

10/10 Excellent
"Great place to stay very clean and restaurant was delicious"
XIOMARY 2-night trip
Posted 2 days ago
Heiss Hotel By Jalo
V Grand Hotel, a member of Radisson Individuals

V Grand Hotel, a member of Radisson Individuals

10/10 Excellent
"Hotel hermoso, buen desayuno y buena localizacion. Volveria a hospedarme sin duda."
Amarilis Solivan 4-night trip
Posted 2 days ago
V Grand Hotel, a member of Radisson Individuals
The Brown, Guatape, Autograph Collection

The Brown, Guatape, Autograph Collection

10/10 Excellent
"The breathtaking views of the river/reservoir of Guatapé are well presented as a backdrop of the Brown hotel. The restaurant felt upscale and the unlimited delicious breakfast and dinner did not disappoint. Get the breakfast included in your package -it’s a GREAT VALUE. Diego our server at the lobby level restaurant was outstanding - anticipating our needs before we even articulated them. We did a beautiful tour of the reservoir and a tour to climb the Piedra Del Peñol and see the small city in Guatape -Gabriel was an excellent tour guide. I enjoyed The Brown so much I’m honestly considering coming back for my 50th next year for a few days with friends. The room was a little small but who cares when you have a large balcony with breathtaking views of the river. The food, vibe, and atmosphere didn’t disappoint. Also what a beautiful gym. Go here - you’ll feel like you found a best kept secret!!"
Kathy 3-night trip
Posted 7 days ago
The Brown, Guatape, Autograph Collection

More cheap stays in El Santuario

Hostal Lleras Calle 8 - Hostel

Hostal Lleras Calle 8 - Hostel

Calle 8 # 37A - 59 Medellín Antioquia
¥4,425
¥4,425 total
Sep 7 - Sep 8
8.4/10 Very Good! (160 reviews)
Hostal Lleras Calle 8 - Hostel
Autenthico Sajonia Hotel Aeropuerto

Autenthico Sajonia Hotel Aeropuerto

Aeropuerto Jose Maria Cordova, Km 20 Rionegro Antioquia
¥9,779
¥9,779 total
Sep 28 - Sep 29
9.2/10 Wonderful! (93 reviews)
Autenthico Sajonia Hotel Aeropuerto
Soy Local Reserva Sajonia

Soy Local Reserva Sajonia

Variante las palmas Rionegro Antioquia
¥10,637
¥10,637 total
Sep 6 - Sep 7
Soy Local Reserva Sajonia
Nakúa Stay + Work

Nakúa Stay + Work

8A-29 Cra. 34 Medellín Antioquia
¥11,259
¥11,259 total
Sep 8 - Sep 9
Nakúa Stay + Work
Masaya Medellin

Masaya Medellin

43a1 Cl. 8 Medellín Antioquia
¥11,263
¥11,263 total
Sep 16 - Sep 17
9.2/10 Wonderful! (208 reviews)
Masaya Medellin
Viajero Hostel Medellin

Viajero Hostel Medellin

Calle 11A # 43D - 11 Medellín Antioquia
¥11,506
¥11,506 total
Oct 3 - Oct 4
Viajero Hostel Medellin

Frequently asked questions

Where is the best place to stay in El Santuario?
Located 21.6 mi (34.7 km) from the heart of El Santuario, Calle Flora Hotel by Jalo is a top choice for your stay based on our traveler data. Other good choices for your visit to the area are Heiss Hotel By Jalo and Hashtag 98 Hotel By Jalo. See all available top hotels, or vacation rentals in El Santuario.
What's the top vacation rental that El Santuario has to offer?
6 Bedrooms House near Tourist Spots with backyard, Bar, Jacuzzi and heated pool: This vacation home rental outside of El Santuario offers an outdoor pool, a patio, and air-conditioning to help you feel perfectly comfortable in your new surroundings. It has 6 bedrooms as well as a kitchen with a fridge, a stovetop, and a microwave, so you can cook with friends or family. You can relax into your vacation with a garden and a hot tub. See all vacation rentals in El Santuario.
If I need to cancel my hotel reservation in El Santuario, will I receive a refund?
Yes, most room reservations are fully refundable if cancelled before the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your arrival date. If you booked a non-refundable reservation, you might still have the option to cancel and get a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in El Santuario.
Where can I learn more about changing or cancelling my trip to El Santuario?
To access more information about updating your trip to El Santuario or cancelling it, click here.
What's it like staying in El Santuario?
Visitors are sure to enjoy all that El Santuario has to offer. In El Santuario, there are 2 hotels and other accommodations to choose from. Find out more about El Santuario.
What are the top places to visit in El Santuario?
Places to visit in the wider area include San Nicolás Mall, Comfama Tutucán Recreational Park, and Rock of Guatapé. You'll also find Llanogrande Mall and Peñol-Guatapé Reservoir in the area. Check out what more to see and do in Expedia's El Santuario guide.
What's the seasonal weather like in El Santuario?
The hottest months are usually August and September with an average temp of 63°F, while the coldest months are January and July with an average of 63°F. The rainiest months in El Santuario are April, May, October, and November, with each month seeing an average of 17 inches of rainfall.

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