An aerial view of a coastal landscape with a river, dense forest, and a beach.

Find hotels in Dewees Island, SC from ￥12,913

Q: What are some of the best vacation rentals in Dewees Island?

Featured "HGTV Dream Home" - Best View on the Oceanfront! : This vacation home rental near Dewees Island is located on the beach and has a fireplace, a balcony, and a barbecue grill to put you at ease in your new surroundings. It has 5 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. Make the most of the garden in this rental home to help you unwind. See all vacation rentals in Dewees Island .

Dates

November 2026

December 2026

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Our top choices for Dewees Island hotels

A hotel lobby with reception desks, seating areas, and a wooden ceiling.

1. Holiday Inn Express & Suites Charleston NE Mt Pleasant US17 by IHG

Mount Pleasant

Patrick

￥18,087 total

includes taxes & fees

Nov 22 - Nov 23

A hotel lobby with seating areas, a reception desk, and decorative lighting.

2. Tru by Hilton Mt Pleasant Charleston

Mount Pleasant

Angela

￥16,451 total

includes taxes & fees

Dec 7 - Dec 8

A spacious dining area with multiple tables and chairs, large windows, and potted plants.

3. Hampton Inn & Suites Charleston/Mt. Pleasant-Isle Of Palms

Mount Pleasant

Erik

￥18,954 total

includes taxes & fees

Nov 29 - Nov 30

A modern hotel lobby with a dining area, a bar, and a television.

4. Springhill Suites by Marriott Charleston Mount Pleasant

Mount Pleasant

Angela

￥18,555 total

includes taxes & fees

Dec 6 - Dec 7

A modern bar area with a wooden ceiling, bar stools, and a counter.

5. Cambria Hotel Mount Pleasant – Charleston

Mount Pleasant

william

￥18,777 total

includes taxes & fees

Nov 23 - Nov 24

A modern living room with a sectional sofa, a flat-screen TV, and a small coffee table.

6. Hyatt House Charleston / Mount Pleasant

Mount Pleasant

Cindy

￥20,272 total

includes taxes & fees

Nov 22 - Nov 23

A pool area with lounge chairs and palm trees, surrounded by a building with a sign that reads 'hotel indigo'.

7. Hotel Indigo Mount Pleasant by IHG

Mount Pleasant

Mary Beth

￥20,717 total

includes taxes & fees

Dec 7 - Dec 8

A cozy outdoor patio with a circular fire pit, seating, and string lights.

8. Home2 Suites By Hilton Mt Pleasant Charleston

Mount Pleasant

Marilyn

￥18,876 total

includes taxes & fees

Nov 15 - Nov 16

A spacious lounge area with a stone accent wall, a flat-screen TV, multiple seating options including sofas and chairs, and a patterned carpet.

9. Staybridge Suites Charleston - Mount Pleasant by IHG

Mount Pleasant

Wesley

￥23,089 total

includes taxes & fees

Nov 22 - Nov 23

A hotel room with a blue sofa, two brown ottomans, a bed with white linens, and three framed pictures on the wall.

10. Comfort Suites at Isle Of Palms Connector

Mount Pleasant

Corey

￥15,363 total

includes taxes & fees

Dec 6 - Dec 7

A swimming pool with lounge chairs and umbrellas, surrounded by trees and a building with multiple windows.

11. Holiday Inn Express & Suites Mt. Pleasant by IHG

Mount Pleasant

Thomas

￥18,447 total

includes taxes & fees

Nov 15 - Nov 16

A spacious living area with a blue sofa set, a glass railing, and a modern kitchen in the background.

12. Hyatt Place Mount Pleasant Towne Centre

Mount Pleasant

Pamela

￥23,525 total

includes taxes & fees

Dec 8 - Dec 9

A modern bar area with wooden bar stools, pendant lighting, and a large window offering a view of the outdoors.

13. Hampton Inn Charleston/Mount Pleasant-Patriots Point

Mount Pleasant

Kelly

￥19,261 total

includes taxes & fees

Dec 6 - Dec 7

An outdoor patio with tables and chairs, palm trees, and a brick building with large windows.

14. Embassy Suites by Hilton Charleston Harbor Mt. Pleasant

Old Village

David

￥26,645 total

includes taxes & fees

Dec 6 - Dec 7

A hotel lobby with a bar area, multiple dining tables, and chairs.

15. Hilton Garden Inn Charleston / Mt. Pleasant

Mount Pleasant

Katie

￥21,158 total

includes taxes & fees

Nov 15 - Nov 16

A bar area with a curved counter, multiple seating options including round tables and chairs, and a patterned floor.

16. DoubleTree by Hilton Charleston Mount Pleasant

Mount Pleasant

Brandon

￥16,496 total

includes taxes & fees

Dec 2 - Dec 3

A covered outdoor area with a pool, palm trees, and lounge chairs.

17. The Beach Club at Charleston Harbor Resort and Marina

Mount Pleasant

Robert

￥27,461 total

includes taxes & fees

Nov 23 - Nov 24

A modern lobby with a staircase, blue armchairs, a round coffee table, and potted plants.

18. SpringHill Suites Charleston Riverview

West Ashley

ROSCOE

￥18,968 total

includes taxes & fees

Nov 22 - Nov 23

A modern kitchen with a large island, bar stools, framed pictures on the wall, and a view of the outside.

19. Quality Inn Mt. Pleasant - Charleston

Mount Pleasant

GENELL

￥15,387 total

includes taxes & fees

Nov 29 - Nov 30

A spacious lobby with a high ceiling, a mezzanine level, and multiple seating areas including sofas and chairs.

20. Comfort Inn & Suites Patriots Point

Mount Pleasant

Vita

￥16,591 total

includes taxes & fees

Nov 29 - Nov 30

View all properties

Compare top hotels in Dewees Island

Holiday Inn Express & Suites Charleston NE Mt Pleasant US17 by IHG 2.5 star property Mount Pleasant View	Tru by Hilton Mt Pleasant Charleston 2.5 star property Mount Pleasant View	Hampton Inn & Suites Charleston/Mt. Pleasant-Isle Of Palms 2.5 star property Mount Pleasant View	Springhill Suites by Marriott Charleston Mount Pleasant 3.0 star property Mount Pleasant View	Cambria Hotel Mount Pleasant – Charleston 3.0 star property Mount Pleasant View
8.8 Excellent 1,000 reviews	9.2 Wonderful 1,487 reviews	9.0 Wonderful 1,002 reviews	8.8 Excellent 1,001 reviews	9.4 Exceptional 2,426 reviews
The price is ￥16,006 ￥18,087 total includes taxes & fees Nov 22 - Nov 23	The price is ￥14,279 ￥16,451 total includes taxes & fees Dec 7 - Dec 8	The price is ￥16,474 ￥18,954 total includes taxes & fees Nov 29 - Nov 30	The price is ￥16,114 ￥18,555 total includes taxes & fees Dec 6 - Dec 7	The price is ￥16,457 ￥18,777 total includes taxes & fees Nov 23 - Nov 24
Yes, Breakfast included Yes, Pool No Spa No Pet friendly Yes, WiFi included Yes, Parking	Yes, Breakfast included Yes, Pool No Spa Yes, Pet friendly Yes, WiFi included Yes, Parking	Yes, Breakfast included Yes, Pool No Spa Yes, Pet friendly Yes, WiFi included Yes, Parking	Yes, Breakfast included Yes, Pool No Spa Yes, Pet friendly Yes, WiFi included Yes, Parking	No Breakfast included Yes, Pool No Spa No Pet friendly Yes, WiFi included Yes, Parking

Learn more about Dewees Island

Check out the local area in Dewees Island as you venture to sights like Dewees Island Beach.

See all hotels in Dewees Island

Top Dewees Island Hotel Reviews

The Beach Club at Charleston Harbor Resort and Marina

Mount Pleasant

10/10 Excellent

Shane

Cambria Hotel Mount Pleasant – Charleston

Mount Pleasant

10/10 Excellent

Christian

Holiday Inn Express & Suites Mt. Pleasant by IHG

Mount Pleasant

10/10 Excellent

Tommy

DoubleTree by Hilton Charleston Mount Pleasant

Mount Pleasant

10/10 Excellent

Lori Lynn

Hyatt House Charleston / Mount Pleasant

Mount Pleasant

10/10 Excellent

Irina

A spacious dining area with high ceilings, large windows, and a variety of seating options including tables and chairs.

Hampton Inn Charleston - Daniel Island

Charleston

10/10 Excellent

Janet S.

Hampton Inn & Suites Charleston/Mt. Pleasant-Isle Of Palms

Mount Pleasant

10/10 Excellent

Erin

Hotel Indigo Mount Pleasant by IHG

Mount Pleasant

10/10 Excellent

Lishibanya

A spacious lobby with high ceilings, large windows, and elegant furniture.

Courtyard by Marriott Charleston Mount Pleasant

Mount Pleasant

10/10 Excellent

Bennita

A bar area with wooden stools and a white counter, overlooking a dock and boats.

Shem Creek Inn

Mount Pleasant

10/10 Excellent

Tammy

A modern hotel room with a bed, bedside tables, a desk, and a balcony with a view.

The Palms Oceanfront Hotel

Downtown Isle of Palms

10/10 Excellent

Anonymous traveler

An outdoor patio area with a fire pit, seating, and a covered section.

Home2 Suites by Hilton Charleston Daniel Island

Charleston

10/10 Excellent

Annika

A hotel with multiple swimming pools, outdoor seating areas, and a large building with balconies.

Wild Dunes Resort – Sweetgrass Inn and Boardwalk Inn

Isle of Palms

10/10 Excellent

Brian

A pool area with lounge chairs and palm trees.

Harborside at Charleston Harbor Resort and Marina

Mount Pleasant

10/10 Excellent

We traveled into Charleston from Seattle. I booked this hotel because I was looking for a good place to relax, unwind, and watch the sunset for my husbands birthday. It beyond met expectations. The front desk staff were extremely helpful (even when I forgot a razor and my daughter forgot her toothbrush) They had FREE ice cream. They even put balloons and a card in our room so I was able to surprise my husband. I can't wait to come back to Charleston. We only stayed one night here and wish I had...

Natashia

Holiday Inn Express & Suites Charleston NE Mt Pleasant US17 by IHG

Mount Pleasant

10/10 Excellent

cumeico

Home2 Suites By Hilton Mt Pleasant Charleston

Mount Pleasant

10/10 Excellent

Debbie

Comfort Inn & Suites Patriots Point

Mount Pleasant

10/10 Excellent

David

Embassy Suites by Hilton Charleston Harbor Mt. Pleasant

Old Village

10/10 Excellent

We have stayed at the property numerous times, and it’s one of our favorites. The rooms are spacious & immaculately clean, as is the rest of the hotel. The location is fantastic for families. You can easily get to Mt. P, IOP, Sullivan’s, downtown. There’s a playground & splash pad within walking distance. The kids love the pool at the hotel. They also loved the daily manager’s reception every evening. They were able to get drinks & snacks while waiting for dinner. Flood in the restaurante is...

LeighAnne

Quality Inn Mt. Pleasant - Charleston

Mount Pleasant

10/10 Excellent

Elaine

Frequently Asked Questions

What are some of the best vacation rentals in Dewees Island?

Featured "HGTV Dream Home" - Best View on the Oceanfront!: This vacation home rental near Dewees Island is located on the beach and has a fireplace, a balcony, and a barbecue grill to put you at ease in your new surroundings. It has 5 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. Make the most of the garden in this rental home to help you unwind. See all vacation rentals in Dewees Island.

If I need to cancel my hotel reservation in Dewees Island, will I receive a refund?

Yes, the majority of hotel bookings are fully refundable as long as you cancel before the accommodation's cancellation deadline, which is usually within 24-48 hours of your scheduled arrival. If you have a non-refundable reservation, you might still have the option to cancel and get a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in Dewees Island.

Where can I learn more about changing or cancelling my trip to Dewees Island?

For additional details about changing or cancelling your trip to Dewees Island, click here.

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Find hotels in Dewees Island, SC from ￥12,913

Change your mind

Treat yourself

Be picky

Go beyond your typical stay in Dewees Island

Check prices for these dates

Filter by

Property class

Guest rating

Our top choices for Dewees Island hotels

1. Holiday Inn Express & Suites Charleston NE Mt Pleasant US17 by IHG

2. Tru by Hilton Mt Pleasant Charleston

3. Hampton Inn & Suites Charleston/Mt. Pleasant-Isle Of Palms

4. Springhill Suites by Marriott Charleston Mount Pleasant

5. Cambria Hotel Mount Pleasant – Charleston

6. Hyatt House Charleston / Mount Pleasant

7. Hotel Indigo Mount Pleasant by IHG

8. Home2 Suites By Hilton Mt Pleasant Charleston

9. Staybridge Suites Charleston - Mount Pleasant by IHG

10. Comfort Suites at Isle Of Palms Connector

11. Holiday Inn Express & Suites Mt. Pleasant by IHG

12. Hyatt Place Mount Pleasant Towne Centre

13. Hampton Inn Charleston/Mount Pleasant-Patriots Point

14. Embassy Suites by Hilton Charleston Harbor Mt. Pleasant

15. Hilton Garden Inn Charleston / Mt. Pleasant

16. DoubleTree by Hilton Charleston Mount Pleasant

17. The Beach Club at Charleston Harbor Resort and Marina

18. SpringHill Suites Charleston Riverview

19. Quality Inn Mt. Pleasant - Charleston

20. Comfort Inn & Suites Patriots Point

Compare top hotels in Dewees Island

Holiday Inn Express & Suites Charleston NE Mt Pleasant US17 by IHG

Tru by Hilton Mt Pleasant Charleston

Hampton Inn & Suites Charleston/Mt. Pleasant-Isle Of Palms

Springhill Suites by Marriott Charleston Mount Pleasant

Cambria Hotel Mount Pleasant – Charleston

Learn more about Dewees Island

Top Dewees Island Hotel Reviews

The Beach Club at Charleston Harbor Resort and Marina

10/10 Excellent

Frequently Asked Questions

What are some of the best vacation rentals in Dewees Island?

If I need to cancel my hotel reservation in Dewees Island, will I receive a refund?

Where can I learn more about changing or cancelling my trip to Dewees Island?

Explore a world of travel with Expedia