Photo by Abby Fieldhouse

Find hotels in Cherokee Seneca, Louisville from ￥7,659

    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
Aug 23 - Aug 24
Tomorrow
Aug 24 - Aug 25
Next weekend
Aug 29 - Aug 31
In two weeks
Sep 5 - Sep 7

Filter by

Guest rating
Guest rating
Star rating

Discover 1,993 Cherokee Seneca hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Our top choices for Cherokee Seneca hotels

Motel 6 Shepherdsville, KY – Louisville South
Front of property - evening/night

Motel 6 Shepherdsville, KY – Louisville South

2.0 star property
7.0 out of 10, Good, (866)
"Great place and great stay"
The price is ￥8,723
￥9,708 total
includes taxes & fees
Aug 24 - Aug 25
Motel 6 Shepherdsville, KY – Louisville South
Hampton Inn & Suites By Hilton Louisville East Oxmoor
Indoor pool

Hampton Inn & Suites By Hilton Louisville East Oxmoor

2.5 star property
9.8 out of 10, Exceptional, (94)
"Great stay "
The price is ￥16,437
￥19,341 total
includes taxes & fees
Sep 3 - Sep 4
Hampton Inn & Suites By Hilton Louisville East Oxmoor
WoodSpring Suites Louisville Southeast
Exterior

WoodSpring Suites Louisville Southeast

2.5 star property
6.6 out of 10, (625)
"Comfortable and cozy"
The price is ￥8,815
￥10,372 total
includes taxes & fees
Aug 24 - Aug 25
WoodSpring Suites Louisville Southeast
Tempo By Hilton Louisville Downtown Nulu
2 restaurants, breakfast served

Tempo By Hilton Louisville Downtown Nulu

3.5 star property
9.4 out of 10, Exceptional, (706)
"Wonderful hotel ! "
The price is ￥18,610
￥21,897 total
includes taxes & fees
Aug 24 - Aug 25
Tempo By Hilton Louisville Downtown Nulu
Derby City Gaming & Hotel - A Churchill Downs Property
1 bedroom, premium bedding, in-room safe, desk

Derby City Gaming & Hotel - A Churchill Downs Property

4.0 star property
9.4 out of 10, Exceptional, (1386)
"Great staff and clean hotel"
Derby City Gaming & Hotel - A Churchill Downs Property
Days Inn & Suites by Wyndham Sellersburg
Desk, laptop workspace, blackout drapes, iron/ironing board

Days Inn & Suites by Wyndham Sellersburg

2.0 star property
7.0 out of 10, Good, (803)
"Very nice for the cost. Very friendly host at desk."
The price is ￥9,992
￥11,292 total
includes taxes & fees
Aug 31 - Sep 1
Days Inn & Suites by Wyndham Sellersburg
Wyndham Garden Louisville KY
Desk, laptop workspace, blackout drapes, iron/ironing board

Wyndham Garden Louisville KY

2.5 star property
8.0 out of 10, Very Good, (127)
"The staff was very friendly, and the breakfast options were great. We loved the four nights we stayed there, and we will be back and will be recommending the hotel to our friends and family. "
The price is ￥10,492
￥12,344 total
includes taxes & fees
Aug 25 - Aug 26
Wyndham Garden Louisville KY
Motel 6 Jeffersonville, In - Louisville
1 bedroom, blackout drapes, WiFi, bed sheets

Motel 6 Jeffersonville, In - Louisville

2.0 star property
6.0 out of 10, (325)
"Slightly of the beaten path which made for a very quiet stay. "
The price is ￥7,659
￥8,655 total
includes taxes & fees
Sep 8 - Sep 9
Motel 6 Jeffersonville, In - Louisville
Home2 Suites By Hilton Shepherdsville Louisville South
Terrace/patio

Home2 Suites By Hilton Shepherdsville Louisville South

3.0 star property
9.4 out of 10, Exceptional, (202)
"Room, amenities, use of lobby computer, etc.....all made for an enjoyable stay. "
The price is ￥16,163
￥17,989 total
includes taxes & fees
Aug 29 - Aug 30
Home2 Suites By Hilton Shepherdsville Louisville South
Hotel Genevieve part of JdV by Hyatt
3 bars/lounges, cocktail bar, rooftop bar

Hotel Genevieve part of JdV by Hyatt

4.0 star property
9.2 out of 10, Wonderful, (937)
"Loved the design and vibe, lots of attention to detail. Service was terrific at the front desk and in the restaurants. Great mini market for coffee and snacks. Other great restaurants and shops nearby."
The price is ￥19,858
￥23,364 total
includes taxes & fees
Aug 24 - Aug 25
Hotel Genevieve part of JdV by Hyatt
Suburban Studios Louisville East
Full-size fridge, microwave, stovetop, cookware/dishes/utensils

Suburban Studios Louisville East

2.0 star property
7.6 out of 10, Good, (43)
"Its really nice and comfortable."
The price is ￥9,243
￥10,875 total
includes taxes & fees
Sep 5 - Sep 6
Suburban Studios Louisville East
Red Roof Inn Louisville Expo Airport
Exterior

Red Roof Inn Louisville Expo Airport

2.0 star property
6.2 out of 10, (1002)
"It was nice "
The price is ￥8,375
￥9,854 total
includes taxes & fees
Sep 22 - Sep 23
Red Roof Inn Louisville Expo Airport
Red Roof Inn Louisville Fair and Expo
Exterior

Red Roof Inn Louisville Fair and Expo

2.0 star property
7.8 out of 10, Good, (1000)
"It was a decent place to stay"
The price is ￥9,073
￥10,676 total
includes taxes & fees
Aug 31 - Sep 1
Red Roof Inn Louisville Fair and Expo
Red Carpet Inn - Louisville
Exterior detail

Red Carpet Inn - Louisville

2.0 star property
6.2 out of 10, (715)
"I love the people they were awesome roxi for sure rocks lol the thing that I didn't enjoyed was the drunk fighting in the middle of the night "
The price is ￥8,270
￥9,729 total
includes taxes & fees
Aug 24 - Aug 25
Red Carpet Inn - Louisville
The Myriad Hotel Louisville, Tapestry Collection by Hilton
Outdoor pool, open 9:00 AM to 10:00 PM, free cabanas, pool umbrellas

The Myriad Hotel Louisville, Tapestry Collection by Hilton

3.5 star property
8.8 out of 10, Excellent, (210)
"Best hotel Great location "
The price is ￥17,361
￥20,428 total
includes taxes & fees
Sep 7 - Sep 8
The Myriad Hotel Louisville, Tapestry Collection by Hilton
La Quinta Inn & Suites by Wyndham Louisville NE/Old Henry Rd
Exterior

La Quinta Inn & Suites by Wyndham Louisville NE/Old Henry Rd

3.0 star property
8.6 out of 10, Excellent, (831)
"Great breakfast, comfy beds"
The price is ￥10,510
￥12,366 total
includes taxes & fees
Aug 31 - Sep 1
La Quinta Inn & Suites by Wyndham Louisville NE/Old Henry Rd
Hilton Garden Inn Jeffersonville Louisville North
Exterior

Hilton Garden Inn Jeffersonville Louisville North

3.0 star property
9.6 out of 10, Exceptional, (329)
"Everything was very clean and a beautiful hotel"
The price is ￥14,216
￥16,064 total
includes taxes & fees
Aug 29 - Aug 30
Hilton Garden Inn Jeffersonville Louisville North
Travelodge by Wyndham Sellersburg / Louisville North
Individually furnished, blackout drapes, iron/ironing board

Travelodge by Wyndham Sellersburg / Louisville North

2.0 star property
6.6 out of 10, (663)
"Stayed over night while traveling through on trip, wonderful clean room and king bed was comfortable. Great hotel for pricing!! "
The price is ￥9,866
￥11,149 total
includes taxes & fees
Aug 30 - Aug 31
Travelodge by Wyndham Sellersburg / Louisville North
Hotel Louisville
Lobby

Hotel Louisville

2.5 star property
6.6 out of 10, (1002)
"It’s a hotel for transients "
Hotel Louisville
Econo Lodge Louisville Airport
Free daily continental breakfast

Econo Lodge Louisville Airport

2.0 star property
6.6 out of 10, (309)
"It was nice "
The price is ￥8,492
￥9,857 total
includes taxes & fees
Aug 31 - Sep 1
Econo Lodge Louisville Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Cherokee Seneca

Find the best Cherokee Seneca areas and neighborhoods for the activities you enjoy most.
Louisville showing signage and street scenes as well as a small group of people

Downtown Louisville

3 out of top 10 points of interest in this area

Explore "Museum Row" in the West Main District, catch a game at Louisville Slugger Field, or stroll across the pedestrian-only Big Four Bridge. Enjoy diverse attractions, restaurants, and the Louie Link skywalk.

Fairgrounds

1 out of top 10 points of interest in this area

While visiting Fairgrounds, you might make a stop by sights like Freedom Hall and Kentucky Kingdom.

Jeffersontown

Jeffersontown is known for its abundant dining options, and you can plan a trip to Jeffersontown Commons Shopping Center and Bluegrass Indoor Karting while you're in town.

Conrad Caldwell House showing heritage elements and signage

Old Louisville

Boasting Victorian architecture and the highest concentration of stained glass windows in residential homes, Old Louisville offers a walkable neighborhood with pedestrian-only streets, diverse dining options, and attractions like Central Park and the Conrad-Caldwell House.

St. Matthews

Major shopping destination with the fifth-largest mall in Kentucky, Mall St. Matthews, and smaller centers along Shelbyville Road. Don't miss the historic St. Matthew's Episcopal Church and Holy Trinity.

Top Cherokee Seneca Hotel Reviews

Hyatt Regency Louisville

Hyatt Regency Louisville

10/10 Excellent
"Honestly it was awesome, my issue was with expedia they had no record of pre paying or my reservation , they took charge and had it resolved i absolutely am going back and the only place im staying at is there.awesome service "
tim 2-night trip
Posted 21 hours ago
Hyatt Regency Louisville

Frequently asked questions

What is Cherokee Seneca like?

You'll be sure to have fun visiting Louisville's Cherokee Seneca neighborhood.

If I need to cancel my hotel reservation in Cherokee Seneca, will I receive a refund?

Yes, you'll find most hotel room reservations are fully refundable provided that you cancel before the hotel’s cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If you have a reservation that's non-refundable, it may still be possible to cancel it and be given a refund within 24 hours of booking. Add your dates and click on "Search", then use the "fully refundable" filter to review top deals in Cherokee Seneca.

Where can I learn more about changing or cancelling my trip to Cherokee Seneca?

To find more details about changing or cancelling your trip to Cherokee Seneca, head over to our customer service page.

What is there to do around this Louisville neighborhood?

Peterson-Dumesnil House, Historic Frankfort Avenue, and Colonel Sanders' Grave are just a few of the places to visit in and around Cherokee Seneca. Muhammad Ali Gravesite and Mid City Mall Shopping Center are also worth a visit when you're out sightseeing in Louisville.