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Check prices for these dates

Next weekend
Jan 2 - Jan 4
In two weeks
Jan 9 - Jan 11
In one month
Jan 23 - Jan 25
In two months
Feb 20 - Feb 22
No exact matches found, but these alternatives could be just right

Recommended hotels in Cairo

Lobby
Quality Inn Cairo I-57

Quality Inn Cairo I-57

Quality Inn Cairo I-57
2.5 star property
Cairo
6.6 out of 10, (274)
"Break fast was excellent "
United States
Uma
The price is ￥11,073
￥12,288 total
includes taxes & fees
Jan 17 - Jan 18, 2026
Quality Inn Cairo I-57
Basic Double Room | Free WiFi
La Center Motel

La Center Motel

La Center Motel
2.0 star property
La Center
7.8 out of 10, Good, (17)
"Quiet and convenient."
United States
Alma
La Center Motel
Front of property - evening/night
Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO
2.0 star property
Charleston
6.6 out of 10, (614)
"Staff was great! Room was nice. "
United States
Lana
The price is ￥9,684
￥10,746 total
includes taxes & fees
Dec 27 - Dec 28
Super 8 by Wyndham Charleston/Sikeston East MO
Desk, iron/ironing board, free WiFi, alarm clocks
Eagle Inn Charleston

Eagle Inn Charleston

Eagle Inn Charleston
2.0 star property
Charleston
6.6 out of 10, (105)
"Middle of nowhere hotel was ok"
United States
David
The price is ￥9,433
￥10,468 total
includes taxes & fees
Jan 26 - Jan 27, 2026
Eagle Inn Charleston
Dining
Cozy cabins on beautiful Horseshoe Lake

Cozy cabins on beautiful Horseshoe Lake

Cozy cabins on beautiful Horseshoe Lake
Olive Branch
9.8 out of 10, Exceptional, (35)
"Beautiful place, host was kind and and quick to respond to messages "
United States
Melissa W.
The price is ￥17,566
￥21,927 total
includes taxes & fees
Dec 27 - Dec 28
Cozy cabins on beautiful Horseshoe Lake
Exterior
Charming cottage overlooking Lake Acre

Charming cottage overlooking Lake Acre

Charming cottage overlooking Lake Acre
Dongola
10.0 out of 10, Exceptional, (101)
"Location was great, everything was great for what we were there for. Already booked again for November. "
United States
carlton h.
The price is ￥21,052
￥43,794 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Charming cottage overlooking Lake Acre
House (2 Bedrooms) | Interior
Quiet Country Stay: Modern Home Near Paducah

Quiet Country Stay: Modern Home Near Paducah

Quiet Country Stay: Modern Home Near Paducah
3.0 star property
Cunningham
The price is ￥18,869
￥45,218 total
includes taxes & fees
Dec 27 - Dec 28
Quiet Country Stay: Modern Home Near Paducah
Interior
The Rested Duck Mallard Room

The Rested Duck Mallard Room

The Rested Duck Mallard Room
Olive Branch
9.2 out of 10, Wonderful, (25)
"This is an excellent place to stay. With a nice lake right across the street. If i. In the are i will stay again for sure"
United States
mike b.
The price is ￥17,566
￥21,927 total
includes taxes & fees
Dec 27 - Dec 28
The Rested Duck Mallard Room
Fridge, microwave, oven, stovetop
Charming 3-bedroom house near ball park in quiet neighborhood

Charming 3-bedroom house near ball park in quiet neighborhood

Charming 3-bedroom house near ball park in quiet neighborhood
Bardwell
10.0 out of 10, Exceptional, (12)
"Quaint stay to see Grand and kids. "
United States
Sheila C.
The price is ￥14,035
￥25,043 total
includes taxes & fees
Jan 2 - Jan 3, 2026
Charming 3-bedroom house near ball park in quiet neighborhood
Exterior detail
Charming Home just minutes from Interstate and Mall

Charming Home just minutes from Interstate and Mall

Charming Home just minutes from Interstate and Mall
Kevil
10.0 out of 10, Exceptional, (20)
"We enjoyed staying here very much. Clean and close to where we wanted to be!"
United States
Becky C.
The price is ￥17,175
￥29,220 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Charming Home just minutes from Interstate and Mall
Interior
Beautiful Cabin Retreat

Beautiful Cabin Retreat

Beautiful Cabin Retreat
tamms
8.2 out of 10, Very Good, (41)
"This is a very nice, peaceful cabin. The host was very friendly and accommodating. I would definitely stay here again."
United States
Randy V.
The price is ￥22,611
￥36,688 total
includes taxes & fees
Jan 5 - Jan 6, 2026
Beautiful Cabin Retreat
Fridge, microwave, stovetop, coffee/tea maker
Quiet Country Stay: Modern Home Near Paducah

Quiet Country Stay: Modern Home Near Paducah

Quiet Country Stay: Modern Home Near Paducah
2.0 star property
Cunningham
The price is ￥16,863
￥44,525 total
includes taxes & fees
Dec 27 - Dec 28
Quiet Country Stay: Modern Home Near Paducah
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Cairo Hotel Reviews

Quiet home on horse farm, halfway between Paducah & Wickliffe. Close to 60 & 286

Quiet home on horse farm, halfway between Paducah & Wickliffe. Close to 60 & 286

10/10 Excellent
"We loved our stay in this country location. It was quiet and peaceful yet close enough to Paducah for shopping and restaurants. The home was spotless, and every amenity was available - basic kitchen supplies (mixer, oil, sugar, spices, and much more), lots of towels and blankets and pillows, wifi and TV, washer and dryer, and more I'm probably not thinking of.It was very cold and snowy during our visit, so we made the home a cozy place to watch movies and relax. We even had our three small dogs with us, and there was lots of yard space to walk them.If you visit here, don't miss the National Quilt Museum. It's not your grandmother's quilt - it's amazing fabric art! Oh, and we found a vegan restaurant we liked: Branch Out.Definitely recommend staying here!!!"
Lynne B. 6-night trip
Posted 3 weeks ago
Quiet home on horse farm, halfway between Paducah & Wickliffe. Close to 60 & 286

Find out more about Cairo

Cairo B&B information

Number of reviews
1,197
Accommodation
0 B&B
Lowest Price
￥10,468
Highest Price
￥43,794

Frequently asked questions

Searching for B&Bs in Cairo?
If you're looking for something a little different than your standard hotel experience, a stay at a bed and breakfast could be a great option for your getaway. When you want to explore some attractions in town, Mississippi River and Ohio River Valley are worth a stop.
How do you know if a B&B is the best choice for your stay?
With attentive service, opportunities to meet other guests, and of course a full breakfast to start the day, B&Bs provide a truly one-of-a-kind setting.
When should I book my B&B in Cairo?
When you're planning your stay in Cairo, be sure to take into account the year-round temperatures. The hottest months are usually July and August with an average temp of 76°F, while the coldest months are January and February with an average of 41°F. Average annual precipitation for Cairo is 61 inches.
What is there to do in Cairo?
Spend some time exploring Mississippi River and Ohio River Valley if you're hoping to see some of the area's natural features. You might check out Fort Defiance State Park if you have time to see more of the area.
How can I get to and around Cairo?
You can map out your trip in and around Cairo ahead of time with these transportation options. Fly into Cairo, IL (CIR-Cairo Regional), which is located 4.7 mi (7.5 km) from the heart of the city. Otherwise, look for flights into Paducah, KY (PAH-Barkley Regional), which is 22.9 mi (36.8 km) away. If you'd like to explore around the area, consider renting a car to take in more sights.