20 Best B&B in Cairo, IL - Bed and Breakfast from ￥8,766

A steel bridge with a sunset in the background.

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Recommended hotels in Cairo

1. Quality Inn Cairo I-57

Cairo

Sharon

￥12,725 total

includes taxes & fees

Aug 17 - Aug 18

Laptop workspace, blackout drapes, cribs (free), WiFi (free)

2. Super 8 by Wyndham Charleston/Sikeston East MO

Charleston

France

￥10,515 total

includes taxes & fees

Aug 16 - Aug 17

Room, 1 King Bed, Non Smoking | View from room

3. Eagle Inn Charleston

Charleston

Jackson

￥12,246 total

includes taxes & fees

Aug 13 - Aug 14

4. La Center Motel

La Center

Carrie

￥8,766 total

includes taxes & fees

Sep 12 - Sep 13

5. The Riverstone Hotel Charleston-Sikeston

Charleston

Bobby

￥11,752 total

includes taxes & fees

Sep 7 - Sep 8

6. Peaceful secluded cabin located near Horseshoe Lake

Miller City

George B.

￥34,766 total

includes taxes & fees

Aug 17 - Aug 18

7. Cozy cabins on beautiful Horseshoe Lake

Olive Branch

Matthew

￥22,364 total

includes taxes & fees

Aug 13 - Aug 14

8. The Rested Duck Mallard Room

Olive Branch

John S.

￥22,364 total

includes taxes & fees

Aug 13 - Aug 14

4 bedrooms, iron/ironing board, WiFi, bed sheets

9. Welcoming 4-bedroom house with AC in charming La Center

La Center

"We stayed here while working on a project, and it was honestly one of the best stays I’ve had. The house was super clean, the beds were very comfortable, and the air conditioning worked great. The neighborhood felt safe, the neighbors were friendly, and the location was very convenient with a grocery store just a couple blocks away and a great pizza place nearby.I would definitely stay here again. Highly recommend!"

Tom R.

￥46,885 total

includes taxes & fees

Sep 9 - Sep 10

10. Peaceful 2-bedroom cabin with AC in welcoming Villa Ridge

Villa Ridge

Alexia G.

￥38,986 total

includes taxes & fees

Aug 16 - Aug 17

Coffee/tea maker, fridge, microwave, stovetop

11. Quiet Country Stay: Modern Home Near Paducah

Cunningham

Sheila C.

￥47,397 total

includes taxes & fees

Aug 17 - Aug 18

Coffee/tea maker, fridge, microwave, oven

12. Charming Home just minutes from Interstate and Mall

Kevil

Deannena H.

￥33,054 total

includes taxes & fees

Aug 30 - Aug 31

13. Quiet Country Stay: Modern Home Near Paducah

Cunningham

￥46,259 total

includes taxes & fees

Aug 17 - Aug 18

14. Charming cottage overlooking Lake Acre

Dongola

john m.

￥40,337 total

includes taxes & fees

Aug 15 - Aug 16

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Top Cairo Hotel Reviews

Quiet home on horse farm, halfway between Paducah & Wickliffe. Close to 60 & 286

10/10 Excellent

"A very clean, quiet, charming house with a fully stocked kitchen. The fresh eggs were delicious and we really enjoyed the property. Jayna was a great host and we would definitely like to return in the future."

The Riverstone Hotel Charleston-Sikeston

8/10 Good

"The ad and picture for the hotel is a little deceiving. It shows a large fountain in front of the front lobby. There was none. This is the former Quality Inn Hotel was not good at all. The hotel has been cleaned up and rebranded. The room was nice. My only concern was all the bugs that were outside the room door and flew into the room when you opened your door at night. The other thing that I did not like was the surprise $100 fee that I had to pay up front for potential damage to the room. This fee was returned during check out."

Beautiful newly renovated farm house overlooking 5 acre lake. **New Rates *

10/10 Excellent

"When I arrived the beauty of the house and property far exceeded my expectations. Walking into home you can feel 100 years of history, but you quickly realize that the Host has been so attentive to every detail imaginable to make your stay incredible. When you’re in the kitchen sitting around the island enjoying time with friends and family take a moment to look at a book that is there on the shelf telling the history of Union county Illinois. This wonderful home is located in Union County Illinois and to my pleasant surprise, I found a picture of my Great Great Grandfather in this book. He was born in 1876. This is 5 Star accommodations and I encourage you to treat yourself to such luxury."

Peaceful 2-bedroom cabin with AC in welcoming Villa Ridge

10/10 Excellent

"Great place to stay with our dogs while in town visiting family. We were kept busy by the activities available in the cabin and enjoyed the peace outside. We were tempted to ride the trails, which looked nice, but only didn’t because we opted for mud. High likelihood we will be back. Our dogs were happy and so were we."

Peaceful secluded cabin located near Horseshoe Lake

10/10 Excellent

"We had a great stay at this cabin. This was a dreamy cabin, cozy, and quiet within beautiful nature. The town was small and cute to enjoy local stuff. The hosts were very nice and friendly and give us really good suggestions to enjoy our stay. Very clean, nicely designed, and accessible. Staying in this cabin is a must if you are in the neighborhood."

Charming Home just minutes from Interstate and Mall

10/10 Excellent

"This place is a cozy, charming, clean, close to everything we wanted to see in Paducah place to stay. The neighborhood is quiet and peaceful. The host is very responsive and helpful. I wish we could have stayed longer. We would stay here again."

Charming cottage overlooking Lake Acre

10/10 Excellent

"This was our second time staying here and we stayed for a full week. Fully enjoyed the time away from home. I did a lot of fishing and my wife did some crafting. Enjoyed a fire down by the lake with roasted hotdogs and s'mores. Grilled for dinner a couple of times also. Other nights we brought pre-prepared meals. It's a great getaway out away from the cities. Be prepared to relaxed and enjoy!"

Find out more about Cairo

Cairo B&B information

Number of reviews	1,745
Accommodation	0 B&B
Lowest Price	￥8,766
Highest Price	￥47,397

Frequently asked questions

Searching for B&Bs in Cairo?

If you're looking for something a little different than your standard hotel experience, a stay at a bed and breakfast could be a great option for your getaway. When you want to explore some attractions in town, Mississippi River and Ohio River Valley are worth a stop.

How do you know if a B&B is the best choice for your stay?

With attentive service, opportunities to meet other guests, and of course a full breakfast to start the day, B&Bs provide a truly one-of-a-kind setting.

When should I book my B&B in Cairo?

When you're planning your stay in Cairo, be sure to take into account the year-round temperatures. The hottest months are usually July and August with an average temp of 76°F, while the coldest months are January and February with an average of 41°F. Average annual precipitation for Cairo is 61 inches.

What is there to do in Cairo?

Spend some time exploring Mississippi River and Ohio River Valley if you're hoping to see some of the area's natural features. You might check out Fort Defiance State Park if you have time to see more of the area.

How can I get to and around Cairo?

You can map out your trip in and around Cairo ahead of time with these transportation options. Fly into Cairo, IL (CIR-Cairo Regional), which is located 4.7 mi (7.5 km) from the heart of the city. Otherwise, look for flights into Paducah, KY (PAH-Barkley Regional), which is 22.9 mi (36.8 km) away. If you'd like to explore around the area, consider renting a car to take in more sights.

Room 1

Change your mind

Treat yourself

Be picky

Check prices for these dates

Recommended hotels in Cairo

1. Quality Inn Cairo I-57

2. Super 8 by Wyndham Charleston/Sikeston East MO

3. Eagle Inn Charleston

4. La Center Motel

5. The Riverstone Hotel Charleston-Sikeston

6. Peaceful secluded cabin located near Horseshoe Lake

7. Cozy cabins on beautiful Horseshoe Lake

8. The Rested Duck Mallard Room

9. Welcoming 4-bedroom house with AC in charming La Center

10. Peaceful 2-bedroom cabin with AC in welcoming Villa Ridge

11. Quiet Country Stay: Modern Home Near Paducah

12. Charming Home just minutes from Interstate and Mall

13. Quiet Country Stay: Modern Home Near Paducah

14. Charming cottage overlooking Lake Acre

Top Cairo Hotel Reviews

Quiet home on horse farm, halfway between Paducah & Wickliffe. Close to 60 & 286

The Riverstone Hotel Charleston-Sikeston

Super 8 by Wyndham Charleston/Sikeston East MO

La Center Motel

Beautiful newly renovated farm house overlooking 5 acre lake. **New Rates *

Peaceful 2-bedroom cabin with AC in welcoming Villa Ridge

Peaceful secluded cabin located near Horseshoe Lake

Charming Home just minutes from Interstate and Mall

Charming cottage overlooking Lake Acre

Find out more about Cairo

Cairo B&B information

Frequently asked questions

Explore a world of travel with Expedia

Find Cairo Bed And Breakfast

Change your mind

Treat yourself

Be picky

Check prices for these dates

Recommended hotels in Cairo

1. Quality Inn Cairo I-57

2. Super 8 by Wyndham Charleston/Sikeston East MO

3. Eagle Inn Charleston

4. La Center Motel

5. The Riverstone Hotel Charleston-Sikeston

6. Peaceful secluded cabin located near Horseshoe Lake

7. Cozy cabins on beautiful Horseshoe Lake

8. The Rested Duck Mallard Room

9. Welcoming 4-bedroom house with AC in charming La Center

10. Peaceful 2-bedroom cabin with AC in welcoming Villa Ridge

11. Quiet Country Stay: Modern Home Near Paducah

12. Charming Home just minutes from Interstate and Mall

13. Quiet Country Stay: Modern Home Near Paducah

14. Charming cottage overlooking Lake Acre

Top Cairo Hotel Reviews

Quiet home on horse farm, halfway between Paducah & Wickliffe. Close to 60 & 286

Find out more about Cairo

Cairo B&B information

Frequently asked questions

Explore a world of travel with Expedia