Find Luxury Hotels in Brentwood, MO

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Check availability on Brentwood Luxury Hotels

Our top choices for Brentwood luxury hotels

Meeting facility
The Ritz-Carlton, St. Louis

The Ritz-Carlton, St. Louis

The Ritz-Carlton, St. Louis
5.0 star property
Clayton
9.2 out of 10, Wonderful, (553)
"Service is exceptional!!!"
United States
Jorge
The price is ￥78,253
￥91,351 total
includes taxes & fees
Dec 21 - Dec 22
The Ritz-Carlton, St. Louis
Rooftop bar
Four Seasons Hotel St Louis

Four Seasons Hotel St Louis

Four Seasons Hotel St Louis
5.0 star property
Downtown St. Louis
9.4 out of 10, Exceptional, (1001)
"The staff was amazing. The bed was so comfortable. "
United States
Mary
The price is ￥65,080
￥76,098 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Four Seasons Hotel St Louis
Breakfast, lunch and dinner served
Live by Loews - St.Louis

Live by Loews - St.Louis

Live by Loews - St.Louis
4.0 star property
Downtown St. Louis
9.4 out of 10, Exceptional, (1103)
"Great staff"
United States
Phillip
The price is ￥23,213
￥27,607 total
includes taxes & fees
Dec 19 - Dec 20
Live by Loews - St.Louis
Casino
Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa
4.5 star property
St. Charles
8.4 out of 10, Very Good, (1003)
"Clean room, wonderful helpful pleasant staff, amenities, everything was great love staying here!"
United States
Robyn
The price is ￥23,703
￥30,286 total
includes taxes & fees
Dec 15 - Dec 16
Ameristar Casino Resort and Spa
Lounge
The Westin St. Louis

The Westin St. Louis

The Westin St. Louis
4.5 star property
Downtown St. Louis
8.6 out of 10, Excellent, (1005)
"Great location "
United States
Gregory
The price is ￥19,861
￥23,223 total
includes taxes & fees
Dec 18 - Dec 19
The Westin St. Louis
Rooftop bar
Hotel Saint Louis, Autograph Collection

Hotel Saint Louis, Autograph Collection

Hotel Saint Louis, Autograph Collection
4.0 star property
Downtown St. Louis
8.8 out of 10, Excellent, (464)
"Everything was definitely worth the stay! "
United States
Briana
The price is ￥24,307
￥28,908 total
includes taxes & fees
Dec 13 - Dec 14
Hotel Saint Louis, Autograph Collection
Casino
HoteLumiere at the Arch - A Caesars Rewards Destination

HoteLumiere at the Arch - A Caesars Rewards Destination

HoteLumiere at the Arch - A Caesars Rewards Destination
4.0 star property
Downtown St. Louis
6.8 out of 10, (1000)
"It was very convenient for us because it was across from the convention center. "
United States
Helen P
The price is ￥18,205
￥24,950 total
includes taxes & fees
Dec 14 - Dec 15
HoteLumiere at the Arch - A Caesars Rewards Destination
Lobby
Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch
4.0 star property
Downtown St. Louis
8.4 out of 10, Very Good, (4000)
"Arch view room is big and comfortable fantastic. . "
United States
Tim
The price is ￥13,972
￥16,477 total
includes taxes & fees
Dec 21 - Dec 22
Hyatt Regency St. Louis at The Arch
Lobby
St. Louis Union Station Hotel, Curio Collection by Hilton

St. Louis Union Station Hotel, Curio Collection by Hilton

St. Louis Union Station Hotel, Curio Collection by Hilton
4.0 star property
Downtown West
8.4 out of 10, Very Good, (1006)
"Nice historic hotel"
United States
Michelle
The price is ￥22,246
￥26,457 total
includes taxes & fees
Dec 18 - Dec 19
St. Louis Union Station Hotel, Curio Collection by Hilton
3 bars/lounges, rooftop bar
Hilton St. Louis at the Ballpark

Hilton St. Louis at the Ballpark

Hilton St. Louis at the Ballpark
4.0 star property
Downtown St. Louis
7.6 out of 10, Good, (1063)
"Clean room, this hotel is great for young people, night activity, 360 rooftop bar always crowded but pretty."
United States
Joan
The price is ￥20,446
￥24,317 total
includes taxes & fees
Dec 21 - Dec 22
Hilton St. Louis at the Ballpark
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Brentwood Hotel Reviews

Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

10/10 Excellent
"Clean room, good breakfast and good location "
Martin 2-night trip
Posted 1 day ago
Clayton Plaza Hotel & Extended Stay

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Frequently asked questions

Are you looking for a luxury hotel for your Brentwood vacation?
Expedia can help you arrange a flight to St. Louis Lambert Intl. Airport (STL) airport or St. Louis, MO (SUS-Spirit of St. Louis) airport, and then you can select from various places to stay that will deliver the luxury you'd like to find. Amenities are important when you plan a vacation, so we make it easy to find what you need to make your stay relaxing and comfortable. If you want an upscale hotel that has a spa, an indoor pool, or luxury bedding, Expedia can help you find the best luxury hotel experience that Brentwood has to offer. During your visit, you might want to enjoy the swimming and walking which Brentwood is known for.
When can I expect good weather in Brentwood?
Planning for the weather is a good way to make your trip to Brentwood relaxing and enjoyable, especially when you're splurging. The hottest months are usually July and August with an average temp of 76°F, while the coldest months are January and February with an average of 37°F. Average annual precipitation for Brentwood is 52 inches.
What's there to see and do in Brentwood?
Take in some sights and attractions while you're in Brentwood by visiting St. Louis Union Station, Gateway Arch, and Saint Louis Galleria Mall. If you have extra time while you're in the area, you might want to see St. Louis Art Museum and St. Louis Zoo.
How can I get around Brentwood?
It's easier to get around town comfortably when you know your options. Make your way to Brentwood Station for metro transit.