Find 4 Star Hotels in Upstate South Carolina, SC from ¥15,283
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Compare Upstate South Carolina 4 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

Grand Bohemian Lodge Greenville, Autograph Collection
Grand Bohemian Lodge Greenville, Autograph Collection
9.6 out of 10, Exceptional, (373)
The price is ¥35,765
¥39,342 total
includes taxes & fees
Sep 2 - Sep 3

The Westin Poinsett Greenville
The Westin Poinsett Greenville
9.2 out of 10, Wonderful, (1000)
The price is ¥24,998
¥27,498 total
includes taxes & fees
Aug 24 - Aug 25

The Shepherd Hotel Downtown Clemson
The Shepherd Hotel Downtown Clemson
9.8 out of 10, Exceptional, (658)
The price is ¥26,454
¥29,364 total
includes taxes & fees
Sep 1 - Sep 2

Hotel Hartness
Hotel Hartness
9.8 out of 10, Exceptional, (575)
The price is ¥25,013
¥32,518 total
includes taxes & fees
Aug 17 - Aug 18

Greenville Marriott
Greenville Marriott
8.6 out of 10, Excellent, (585)
The price is ¥18,030
¥20,487 total
includes taxes & fees
Aug 22 - Aug 23

Mint House Greenville - Downtown
Mint House Greenville - Downtown
9.2 out of 10, Wonderful, (711)
The price is ¥16,493
¥18,636 total
includes taxes & fees
Aug 17 - Aug 18

The Abernathy of Clemson
The Abernathy of Clemson
9.6 out of 10, Exceptional, (538)

Park Place Apartments by Landing
Park Place Apartments by Landing
7.8 out of 10, Good, (37)
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Learn more about Upstate South Carolina
Venture to sights like Discovery Island Water Park and Heritage Park as you discover Upstate South Carolina.

Photo by South Carolina Department of Parks, Recreation & Tourism
Open Photo by South Carolina Department of Parks, Recreation & Tourism
Top Upstate South Carolina Hotel Reviews

Grand Bohemian Lodge Greenville, Autograph Collection
10/10 Excellent
Explore a world of travel with Expedia
Explore a world of travel with Expedia
Upstate South Carolina Hotels by Star Rating
Hotels in Upstate South Carolina Neighborhoods
- Greenville Downtown Hotels
- West End Hotels
- Green Avenue Hotels
- Colonel Elias Earle Historic District Hotels
- Pine Ridge Point Hotels
- Pettigru Street Historic District Hotels
- Hampton-Pinckney Historic District Hotels
- Serenity Bay Hotels
- Woodside Cotton Mill Village Historic District Hotels
- Indian Oaks Hotels
Stay near popular Upstate South Carolina attractions
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Explore more hotels
- Embassy Suites Greenville Golf Resort & Conference Center
- Comfort Inn Greenville - Haywood Mall
- Lakeside Lodge Clemson
- Hyatt Place Greenville Downtown
- Inn @ Clemson
- Comfort Suites Greenville Airport
- Midtown Suites-Greenville
- Hampton Inn & Suites Greenville-Downtown-RiverPlace
- The Shepherd Hotel Downtown Clemson
- ECHO Suites Extended Stay by Wyndham Spartanburg
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