Photo by Ryan Watts

Find hotels in Upstate South Carolina, SC from ¥11,009
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Go beyond your typical stay in Upstate South Carolina
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Our top choices for Upstate South Carolina hotels

Carolina Inn Anderson Clemson Area
Carolina Inn Anderson Clemson AreaAnderson
10.0 out of 10, Exceptional, (2 reviews)
The price is ¥8,737
¥9,698 total
includes taxes & fees
May 24 - May 25

Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG
Holiday Inn Express Hotel & Suites Anderson-I-85 by IHGAnderson
9.2 out of 10, Wonderful, (618 reviews)
The price is ¥16,838
¥18,691 total
includes taxes & fees
Jun 19 - Jun 20

Quality Inn Seneca Clemson Area US-123
Quality Inn Seneca Clemson Area US-123Downtown
8.0 out of 10, Very Good, (703 reviews)
The price is ¥14,154
¥16,590 total
includes taxes & fees
Jun 15 - Jun 16

Hampton Inn Gaffney
Hampton Inn GaffneyGaffney
8.8 out of 10, Excellent, (718 reviews)
The price is ¥12,843
¥13,999 total
includes taxes & fees
May 31 - Jun 1

Carolina Camp Cedar
Carolina Camp CedarPickens
10.0 out of 10, Exceptional, (3 reviews)
The price is ¥25,235
¥41,234 total
includes taxes & fees
May 25 - May 26

Lakeside Lodge Clemson
Lakeside Lodge ClemsonSeneca
9.0 out of 10, Wonderful, (1,000 reviews)
The price is ¥17,315
¥21,495 total
includes taxes & fees
May 23 - May 24

Deluxe Inn
Deluxe InnMauldin
10.0 out of 10, Exceptional, (2 reviews)
The price is ¥10,008
¥11,009 total
includes taxes & fees
May 30 - May 31

Fairfield Inn & Suites Seneca Clemson Univ Area
Fairfield Inn & Suites Seneca Clemson Univ AreaSeneca
9.4 out of 10, Exceptional, (231 reviews)
The price is ¥20,535
¥22,588 total
includes taxes & fees
May 26 - May 27

Embassy Suites Greenville Golf Resort & Conference Center
Embassy Suites Greenville Golf Resort & Conference CenterGreenville
9.0 out of 10, Wonderful, (1,208 reviews)
The price is ¥17,418
¥19,159 total
includes taxes & fees
May 31 - Jun 1

Tru by Hilton Seneca Clemson
Tru by Hilton Seneca ClemsonSeneca
9.2 out of 10, Wonderful, (840 reviews)
The price is ¥18,198
¥20,018 total
includes taxes & fees
Jun 16 - Jun 17

Best Western Plus Greenville I-385 Inn & Suites
Best Western Plus Greenville I-385 Inn & SuitesGreenville
9.2 out of 10, Wonderful, (1,475 reviews)
The price is ¥13,011
¥14,313 total
includes taxes & fees
May 31 - Jun 1

Holiday Inn Express Gaffney by IHG
Holiday Inn Express Gaffney by IHGGaffney
8.8 out of 10, Excellent, (489 reviews)
The price is ¥13,502
¥14,719 total
includes taxes & fees
May 31 - Jun 1

Inn on the Square, an Ascend Collection Hotel
Inn on the Square, an Ascend Collection HotelUptown Greenwood
9.2 out of 10, Wonderful, (736 reviews)
The price is ¥19,467
¥21,610 total
includes taxes & fees
May 31 - Jun 1

Hampton Inn Easley
Hampton Inn EasleyEasley
9.2 out of 10, Wonderful, (710 reviews)
The price is ¥19,408
¥21,544 total
includes taxes & fees
Jun 7 - Jun 8

Urban Boutique Hotel, BW Signature Collection
Urban Boutique Hotel, BW Signature CollectionGreenville
8.0 out of 10, Very Good, (1,000 reviews)
The price is ¥10,483
¥11,530 total
includes taxes & fees
May 24 - May 25

Best Western Seneca-Clemson
Best Western Seneca-ClemsonSeneca
8.4 out of 10, Very Good, (660 reviews)
The price is ¥15,528
¥17,081 total
includes taxes & fees
May 24 - May 25

The Abernathy of Clemson
The Abernathy of ClemsonClemson
9.6 out of 10, Exceptional, (600 reviews)
The price is ¥21,140
¥23,465 total
includes taxes & fees
Jun 18 - Jun 19

Best Western Spartanburg Northwest
Best Western Spartanburg NorthwestSpartanburg
8.4 out of 10, Very Good, (901 reviews)
The price is ¥14,042
¥15,586 total
includes taxes & fees
Jun 1 - Jun 2

Aloft by Marriott Greenville Downtown
Aloft by Marriott Greenville DowntownGreenville Downtown
9.2 out of 10, Wonderful, (1,001 reviews)
The price is ¥21,283
¥24,113 total
includes taxes & fees
May 31 - Jun 1

Clemson University's James F. Martin Inn
Clemson University's James F. Martin InnClemson
9.4 out of 10, Exceptional, (1,011 reviews)
The price is ¥23,669
¥26,273 total
includes taxes & fees
May 24 - May 25
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Vacation Rentals in Upstate South Carolina
Cabin

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott BonvoySeneca
9.8 out of 10, Exceptional, (73 reviews)
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Stay near popular Upstate South Carolina attractions
Learn more about Upstate South Carolina
Venture to sights like Discovery Island Water Park and Heritage Park as you discover Upstate South Carolina.

Photo by Ryan Watts
Open Photo by Ryan Watts
Top Upstate South Carolina Hotel Reviews

Drury Inn & Suites Greenville
10/10 Excellent
More cheap stays in Upstate South Carolina

Sleep Inn Spartanburg Southwest
501 South Blackstock Rd Spartanburg SC
The price is ¥9,986 per night from Jun 7 to Jun 8
¥9,986
¥11,084 total
Jun 7 - Jun 8
includes taxes & fees
6/10 (604 reviews)
Hotels in Upstate South Carolina with star-rating

4 Star Hotels
35 properties
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