Upstate South Carolina Vacations

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Where to stay in Upstate South Carolina

Find the best Upstate South Carolina areas and neighborhoods for the activities you enjoy most. Learn more about Upstate South Carolina
Greenville Downtown

Greenville Downtown

2 out of top 10 points of interest in this area
5/5(657 area reviews)

The ample dining options and beautiful river views are top of the list for many visitors to Greenville Downtown. A stop by The Peace Center or Bon Secours Wellness Arena might round out your trip.

Find hotels in Greenville Downtown

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Upstate South Carolina Hotel Deals

Hilton Greenville

Hilton Greenville

3.5 out of 5
45 W Orchard Park Dr Greenville SC
Fully refundableReserve now, pay when you stay
The price is ￥18,831 per night from May 17 to May 18
￥18,831
￥21,277 total
May 17 - May 18
includes taxes & fees
8.2/10 Very Good! (1,009 reviews)
Pffft

Reviewed on Apr 25, 2026

Hilton Greenville
Embassy Suites Greenville Golf Resort & Conference Center

Embassy Suites Greenville Golf Resort & Conference Center

3.5 out of 5
670 Verdae Blvd Greenville SC
Fully refundableReserve now, pay when you stay
The price is ￥20,185 per night from May 17 to May 18
￥20,185
￥22,203 total
May 17 - May 18
includes taxes & fees
9/10 Wonderful! (1,170 reviews)
My air conditioner in my room, seemed like it didnt want to really cool off my room. I changed the air temperature at 10pm, got upbat 12 still the same. I put the air on 60 at 10pm At 3am the room was still 72...i was HOTTTT all night. Hair all in the tub, and on the walls👱‍♀️ and a wash cloth on ...

Reviewed on Apr 26, 2026

Embassy Suites Greenville Golf Resort & Conference Center
Hyatt Place Greenville/Haywood

Hyatt Place Greenville/Haywood

3 out of 5
40 W Orchard Park Dr Greenville SC
Fully refundableReserve now, pay when you stay
The price is ￥14,631 per night from May 25 to May 26
￥14,631
￥16,577 total
May 25 - May 26
includes taxes & fees
7.8/10 Good! (1,005 reviews)
The elevators need a lot of work done to them. The doors open slow or half way at very slow speed.

Reviewed on Apr 27, 2026

Hyatt Place Greenville/Haywood
See all 3,037 properties in Upstate South Carolina
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Discover the most popular places to visit in Upstate South Carolina

"Clemson University is an American public, coeducational, land-grant and sea-grant research university located in Clemson, South Carolina, United States.More clemson images:"

Clemson University

5/5(423 reviews)

Enjoy the collegiate vibe when you visit Clemson University, during your travels in Clemson. Experience the area's theater scene or attend a football game.

Clemson University
Fred W. Symmes Chapel

Fred W. Symmes Chapel

5/5(12 reviews)

You can find out about the history of Cleveland when you stop by Fred W. Symmes Chapel. Wander the lakeside and forest in this relaxing area.

Fred W. Symmes Chapel

BMW Performance Center

4.5/5(46 reviews)

You can spend an afternoon browsing the exhibits at BMW Performance Center during your travels in Greer. While in this family-friendly area, you can savor the charming coffeehouses.

BMW Performance Center

What to do in Upstate South Carolina

Greenville: Saturday Morning Breakfast Tour

Greenville: Saturday Morning Breakfast Tour

￥14,343
per adult
Greenville: Saturday Morning Breakfast Tour
Paranormal Walking Tour by Greenville Ghost Tours

Paranormal Walking Tour by Greenville Ghost Tours

￥5,578
per adult
Paranormal Walking Tour by Greenville Ghost Tours
Cedar Rapids Scavenger Hunt by Operation City Quest

Cedar Rapids Scavenger Hunt by Operation City Quest

￥1,594
per adult
Cedar Rapids Scavenger Hunt by Operation City Quest
See all activities in Upstate South Carolina

Frequently asked questions

Can I cancel my flight booking to Upcountry South Carolina due to COVID-19?
Check out our Customer Service Portal for important details about changing your flights because of COVID-19. Also, read through the terms and conditions of the airline you're considering before booking your trip to Upcountry South Carolina.
What's the best way to find cheap flights to Upcountry South Carolina that have flexible change policies?
When it comes to flying these days, flexibility is a must. That's why we've added a "No change fee" filter to help you find flexible, cheap airfares to Upcountry South Carolina. It's to the left of your screen just below the "Flexible change policies" subheading.
What are some of the general tips for travelers to Upcountry South Carolina during the COVID-19 outbreak?
With strict COVID-19 precautions in place, travel looks a lot different at the moment. Here's what you need to know before you hop on that plane to Upcountry South Carolina:
  • Look into what, if any, restrictions or rules apply to both your destination and origin. You may not be able to travel depending on local circumstances, so make sure you check before you lock something in.
  • You must wear a face mask at the airport, even at screening checkpoints. Be prepared to lower your mask for ID verification when asked by a TSA employee.
  • Rather than handing a TSA agent your boarding pass, position it straight on the scanner yourself. Once that's done, hold it up for inspection.
  • TSA now allows passengers to take one container of hand sanitizer, up to 12 oz (350 ml) in size, in carry-on luggage. This will need to be removed from your bag for screening.
  • Place any personal items (e.g, keys, phone and coins) in your carry-on rather than a bin to reduce handling during screening.
  • Separate any food you have for X-ray screening. Food items often set off the alarm. Placing them in a clear plastic bag and into a bin reduces the need for a TSA employee to handle and inspect your belongings.

Which airlines fly to Upcountry South Carolina?
Delta is a major airline servicing Upcountry South Carolina. Book an airfare to Charleston Intl. Airport (CHS) and you'll have 547 Delta flights each month to pick from.
How can I find cheap tickets to Upcountry South Carolina?
One of the best ways to nab cheap tickets to Upcountry South Carolina is to be flexible with your travel dates. Search for your flights, then click "flexible dates" at the top of your results. It will bring up the cheapest prices for nearby days. The best price for a flight to Upcountry South Carolina in the last seven days was . Booking well ahead of time will usually help you score an even bigger bargain.
How much is a flight to Upcountry South Carolina?
There were lots of budget-friendly fares up for grabs in the last seven days, with the cost of a return flight to Upcountry South Carolina varying between and . Many lucky travelers locked in one-way seats from () for just .
What are the most popular airports to fly into in Upcountry South Carolina?
Fly into Charleston Intl. Airport (CHS) and enjoy all that Upcountry South Carolina has to offer. As the region's primary entry point, approximately 2891 flights touch down here each month.
When is the cheapest time to fly to Upcountry South Carolina?
If you'd prefer to spend your vacation dollars enjoying the best of Upcountry South Carolina rather than on flying there, take off earlier in the week. The most cost-effective day to travel is generally Tuesday, with Monday close behind. With many people traveling over the weekend, Saturday typically has the costliest airfares.
How much is a plane ticket to Upcountry South Carolina?
Ticket prices ranged anywhere from to in the last seven days. When you're ready to book, we'll be ready to help you grab a cheap flight to Upcountry South Carolina.
Which airlines with flights to Upcountry South Carolina employ COVID-19 cleanliness policies?
Physical distancing is the tip of the iceberg for new travel strategies to help fight COVID-19. From your first steps on board, these carriers will take you to your destination with greater peace of mind:
  • American Airlines - this airline is known for providing passenger masks and cleaning with disinfectant.
  • United Airlines - this airline is known for providing passenger masks and cleaning with disinfectant.
  • Delta - this airline is known for electrostatic cleaning and cleaning with disinfectant.

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