Upstate South Carolina Vacations

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Where to stay in Upstate South Carolina

Find the best Upstate South Carolina areas and neighborhoods for the activities you enjoy most. Learn more about Upstate South Carolina
Greenville featuring autumn leaves, a garden and a bridge

Greenville Downtown

3 out of top 10 points of interest in this area
5/5(654 area reviews)

The ample dining options and beautiful river views are top of the list for many visitors to Greenville Downtown. A stop by The Peace Center or Bon Secours Wellness Arena might round out your trip.

Find hotels in Greenville Downtown

Upstate South Carolina Hotel Deals

Best Western Plus Greenville I-385 Inn & Suites
Best Western Plus Greenville I-385 Inn & Suites
2.5 out of 5
831 Congaree Rd, Greenville, SC
Fully refundableReserve now, pay when you stay
The price is ￥14,796 per night from Jun 23 to Jun 24
￥14,796
per night
Jun 23 - Jun 24
9/10 Wonderful! (1,229 reviews)
"It was a great hotel and the price was super reasonable. The hotel staff were accessible, and helpful to answer any questions I had."

Reviewed on Jun 13, 2024

Best Western Plus Greenville I-385 Inn & Suites
Hilton Greenville
Hilton Greenville
3.5 out of 5
45 W Orchard Park Dr, Greenville, SC
The price is ￥14,878 per night from Jul 7 to Jul 8
￥14,878
per night
Jul 7 - Jul 8
8/10 Very Good! (1,007 reviews)
"The hotel and staff were great. The room was renovated and comfortable."

Reviewed on Jun 14, 2024

Hilton Greenville
Hotel Hartness
Hotel Hartness
4 out of 5
120 Halston Avenue, Greenville, SC
The price is ￥22,412 per night from Jun 24 to Jun 25
￥22,412
per night
Jun 24 - Jun 25
9.8/10 Exceptional! (219 reviews)
Beautiful Place to Enjoy and Relaxing!
"We really enjoy the Hotel, a great services, great housekeeping Staff, a great relaxing place to enjoy the pool and beautifull trails around the Hotel. Good Relaxing Music around, best place to get your Spa and restaurant to get your favorite Drinks. Awesome everything!🎖️"

Reviewed on Jun 13, 2024

Hotel Hartness
See all 2,530 properties in Upstate South Carolina
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Upstate South Carolina vacation package cost?
Our Upstate South Carolina vacation packages, which begin from just , are an awesome way to save loads of cash. Choose your preferred flights, hotels and rental cars to create your dream getaway.
How do I get a cheap travel package to Upstate South Carolina?
You’ll save piles of cash if you bundle your hotels, flights and car rentals into a Upstate South Carolina vacation package. Sometimes cheap packages mean fewer options. But that’s not the case with Expedia. We offer more than 550 partner airlines and 1,000,000 hotels across the world, so you’ll always have plenty of options to choose from. Eager to save even more? Add some fun activities to your package deal to unlock even bigger bargains! After all, travel is about more than simply getting to your destination.
Where should I stay in Upstate South Carolina?
Falls Park on the Reedy is one of the main things that attracts visitors to Upstate South Carolina, so it makes perfect sense that many choose to book their hotel in Greenville.
What are the top hotels in Upstate South Carolina?
Best Western Plus Greenville I-385 Inn & Suites and Comfort Inn Greenville - Haywood Mall know how to make their guests feel at home in Greenville. If you also plan to explore Seneca, take a look at Quality Inn Seneca US-123 and Tru by Hilton Seneca Clemson. Both are very popular with travelers.
How far in advance should I book my Upstate South Carolina vacation?
It can be hard to know exactly when the best time is to book your Upstate South Carolina vacation. But typically the earlier you book, the more affordable the prices. Sometimes, you can lock in your flights and hotels up to 12 months prior to departure. If you’re considering a last-minute getaway, no need to fret! There are plenty of fantastic bargains announced on Expedia every single day.
What does an Expedia Upstate South Carolina travel package include?
That depends on what sort of trip you have in mind. Upstate South Carolina vacation deals can include car rentals, flights and hotels. You can mix and match to find the travel package that suits your budget and style. You can also add on activities and experiences after you’ve booked to score even bigger discounts.
What should I know before booking a Upstate South Carolina travel package?
An Expedia travel package can be customized for your budget and is a fantastic way to make your budget go further. What you include is totally up to you. Rental cars, hotels and flights — decide on a combination that suits your style.
Can I choose my airline with a Upstate South Carolina Expedia vacation package?
Yes, of course. Expedia has access to more than 550 airline partners globally, so go with the carrier that best fits your budget and travel needs.
If I'm not able to travel, can I cancel my Upstate South Carolina vacation package?
If your travel plans in Upstate South Carolina have been upended, it’s comforting to know that you can cancel your booking. If you made your booking in the last 24 hours, you may be eligible for a refund. If your booking was made more than 24 hours ago, your airline, hotel or car rental company may impose fees. To learn more, check our Customer Service Portal.

Discover the most popular places to visit in Upstate South Carolina

Image for Clemson University

Clemson University

5/5(410 reviews)

Enjoy the collegiate vibe when you visit Clemson University, during your travels in Clemson. Experience the area's theater scene or attend a football game.

Clemson University
Image for Tallulah Gorge State Park

Tallulah Gorge State Park

4.5/5(144 reviews)

Explore the great outdoors with a trip to Tallulah Gorge State Park, a popular green space in Helen. Discover the area's mountain views and waterfalls.

Tallulah Gorge State Park
Image for Lake Keowee

Lake Keowee

4.5/5(101 reviews)

Commune with nature and explore the great outdoors at Lake Keowee during your travels in Salem. While you're in the area, wander around the college campus.

Lake Keowee

What to do in Upstate South Carolina

Image for Thirsty Thursdays Tour (cocktails and appetizers)

Thirsty Thursdays Tour (cocktails and appetizers)

￥13,111
Per adult
100% of travellers recommend
Thirsty Thursdays Tour (cocktails and appetizers)
See all activities in Upstate South Carolina

Other vacations you might like

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.