A large eye sculpture in a park surrounded by trees.

Find 4 Star Hotels in Northeast Missouri, MO from ￥18,732

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Check availability on Northeast Missouri 4 Star Hotels

Tonight
Sep 26 - Sep 27
Tomorrow
Sep 27 - Sep 28
Next weekend
Oct 2 - Oct 4
In two weeks
Oct 9 - Oct 11

Our top choices for Northeast Missouri 4-star hotels

A buffet with fruits, pastries, and beverages.
A modern living room with a flat-screen TV, comfortable seating, and decorative items on shelves.
A spacious hotel lobby with multiple seating areas, a reception desk, and large windows offering a view of the cityscape.
The Renaissance Hotel with a modern architectural design, featuring a prominent central entrance and a symmetrical facade.

1. Renaissance St. Louis Airport Hotel

Renaissance St. Louis Airport Hotel
Berkeley
United States
Anthony
￥18,583
￥21,740 total
includes taxes & fees
Oct 4 - Oct 5
Renaissance St. Louis Airport Hotel
A multi-story building with a symmetrical facade, large windows, and a central entrance with a canopy.
A reception desk with a wooden finish and the name "IDOL WOLF" on it.
A spacious lobby with multiple seating areas, a pool table, and artwork on the walls.
A spacious lobby with a large spherical sculpture, a seating area, and a view of the outside through a large window.

2. 21C Museum Hotel St Louis

21C Museum Hotel St Louis
Downtown West
United States
Zane
￥22,595
￥27,207 total
includes taxes & fees
Oct 26 - Oct 27
21C Museum Hotel St Louis
A cozy lounge area with leather sofas, a fireplace, and a bar counter.
A restaurant with a central bar area, seating arrangements, and a fireplace.
An outdoor patio area with a pool, red umbrellas, and seating arrangements.
A traditional building with a stone facade, large windows, and outdoor seating area with wicker furniture.

3. The Cheshire

The Cheshire
Richmond Heights
United States
Matthew
￥23,560
￥27,974 total
includes taxes & fees
Oct 11 - Oct 12
The Cheshire
A modern outdoor lounge area with seating, a bar, and a view of a cityscape.
The exterior of the Clark & Bourbon hotel with a well-lit entrance, a marquee sign, and a landscaped planter area.
A modern bar area with a central fire feature, bar stools, and seating.
A modern living room with a sofa, coffee table, and bookshelves.

4. Live by Loews - St.Louis

Live by Loews - St.Louis
Downtown St. Louis
United States
Frank
￥25,008
￥29,741 total
includes taxes & fees
Sep 27 - Sep 28
Live by Loews - St.Louis
A modern hotel room with a large bed, a nightstand, a mirror, and a view of the city through arched windows.
A modern living room with a grey sofa, a round wooden coffee table, and a large window with a city view.
A modern restaurant interior with high tables, chairs, and a central bar area.
A lobby with wooden paneling, a green wall, and two armchairs.

5. The Westin St. Louis

The Westin St. Louis
Downtown St. Louis
United States
Joanne
￥20,817
￥24,341 total
includes taxes & fees
Oct 18 - Oct 19
The Westin St. Louis
A hotel with a swimming pool, lounge chairs, and a courtyard with palm trees.
A grand lobby with a central seating area, a staircase, and a decorative ceiling.
A bar area with a marble counter, bar stools, and a variety of liquor bottles.
A restaurant with multiple dining tables and chairs, a bar area with shelves of bottles, and a large mirror above the bar.

6. The Royal Sonesta Chase Park Plaza St. Louis

The Royal Sonesta Chase Park Plaza St. Louis
Central West End
United States
Tosha
￥23,435
￥32,273 total
includes taxes & fees
Oct 4 - Oct 5
The Royal Sonesta Chase Park Plaza St. Louis
A long bar with multiple tables and chairs, wooden floors, and ornate chandeliers.
A large hotel with a prominent "RIVER CITY" sign.
A spacious hotel lobby with a central seating area, multiple armchairs, and a bar.
A casino with multiple gaming tables and slot machines.

7. River City Casino & Hotel

River City Casino & Hotel
St. Louis
United States
Ashley
￥14,129
￥18,732 total
includes taxes & fees
Oct 11 - Oct 12
River City Casino & Hotel
A rooftop terrace with outdoor seating, string lights, and a city skyline view.
A modern lounge area with a central cylindrical light fixture, white seating, and artwork on the walls.
A modern hotel room with a large window, a bathtub, and a unique eye-themed pillow.
A multi-story hotel with a classic architectural style, featuring a prominent entrance and a series of uniformly lit windows.

8. Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
Grand Center
Canada
Timothy
￥18,745
￥22,106 total
includes taxes & fees
Oct 5 - Oct 6
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
An indoor swimming pool with clear glass walls, metal railings, and a tiled floor.
A bar area with multiple seating arrangements, a stage, and a chandelier.
A grand lobby with a central chandelier, multiple levels, and rows of liquor bottles.
A bakery display case with various pastries and cakes.

9. Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa
St. Charles
United States
Melissa
￥23,474
￥30,042 total
includes taxes & fees
Oct 12 - Oct 13
Ameristar Casino Resort and Spa
A multi-story hotel with a prominent 'Marriott' sign, featuring a classic architectural style with a red brick facade and large windows.
A grand hall with rows of chairs arranged for an event, a central floral arrangement, and a large chandelier.
A spacious lobby with a high ceiling, a bar area, multiple seating arrangements, and a large screen displaying a sports event.
A spacious interior with a central staircase, large windows, and hanging chandeliers.

10. Marriott St. Louis Grand

Marriott St. Louis Grand
Downtown St. Louis
United States
Andrew
￥23,907
￥28,430 total
includes taxes & fees
Oct 4 - Oct 5
Marriott St. Louis Grand
A rooftop restaurant with round tables, chairs, and a view of the city.
A modern lobby with a staircase, seating area, and an exit sign.
A rooftop terrace with seating areas, a decorative moon sculpture, and string lights.
A hotel with a prominent sign reading "MOONRISE."

11. Moonrise Hotel

Moonrise Hotel
Delmar Loop
United States
Nicole
￥20,759
￥24,689 total
includes taxes & fees
Sep 30 - Oct 1
Moonrise Hotel
A restaurant with round tables and chairs, a bar area, and a patterned ceiling.
A lobby with a reception desk, seating area with sofas and ottomans, and a patterned rug.
A spa bath with a sign indicating a capacity of 8 persons.
A Drury Plaza Hotel with a large parking lot and multiple cars parked in front.

12. Drury Plaza Hotel St. Louis Brentwood

Drury Plaza Hotel St. Louis Brentwood
Brentwood
United States
Jeana
￥21,389
￥25,394 total
includes taxes & fees
Oct 4 - Oct 5
Drury Plaza Hotel St. Louis Brentwood
A multi-story hotel with a prominent corner location, large windows, and a well-lit facade.
A bar area with a long counter, multiple stools, and a television mounted on the wall.
A spacious lobby with striped chairs, a central coffee table, and large potted plants.
An indoor swimming pool area with lounge chairs, a small table, and potted plants.

13. Embassy Suites by Hilton St. Louis Downtown

Embassy Suites by Hilton St. Louis Downtown
Downtown St. Louis
United States
Karen
￥18,094
￥21,519 total
includes taxes & fees
Oct 11 - Oct 12
Embassy Suites by Hilton St. Louis Downtown
A modern lounge with a central fire feature, comfortable seating, and large windows offering a city view.
A rooftop terrace with a glass table, cushioned seating, and a view of the cityscape.
A modern bar area with high tables and stools, large windows with city views, and green chandeliers.
A rooftop bar with a glass railing, yellow bar stools, and a large umbrella.

14. Hilton St. Louis at the Ballpark

Hilton St. Louis at the Ballpark
Downtown St. Louis
United States
Scott
￥23,086
￥27,456 total
includes taxes & fees
Oct 2 - Oct 3
Hilton St. Louis at the Ballpark
A brick building with a tower, large windows, and a fountain in the garden.
A grand staircase with a curved design, leading to an upper floor.
A pool area with lounge chairs and umbrellas, a clear blue pool, and a building with a dome in the background.
A spacious lobby with a chandelier, seating area, and a central table with a vase of flowers.

15. Hilton St. Louis Frontenac

Hilton St. Louis Frontenac
Frontenac
United States
Michael and Julie
￥23,086
￥26,892 total
includes taxes & fees
Oct 4 - Oct 5
Hilton St. Louis Frontenac
A rooftop pool area with multiple lounge chairs and umbrellas, surrounded by a modern building with large windows.
A bar area with a round table, ice-filled glasses, bottles of champagne, and decorative plants.
A long dining table set with candles, glassware, and white flowers, suggesting a formal dining experience.
A cozy living room with a large TV, a fireplace, a Christmas tree, and a view of the city.

16. Le Méridien St. Louis Clayton

Le Méridien St. Louis Clayton
Clayton
United States
Steven
￥23,930
￥28,176 total
includes taxes & fees
Oct 4 - Oct 5
Le Méridien St. Louis Clayton
A modern dining area with round tables, orange chairs, and a decorative wall with pottery.
A modern hotel lobby with a bar area, seating arrangements, and decorative lighting.
A swimming pool with a glass enclosure, a lounge area with orange chairs, and a view of a landscaped garden.
A Marriott hotel with a large building, multiple flags, and a well-lit entrance area.

17. Marriott St. Louis Airport

Marriott St. Louis Airport
Edmundson
United States
Chris
￥20,915
￥24,959 total
includes taxes & fees
Oct 3 - Oct 4
Marriott St. Louis Airport
A bar area with a central bar, multiple stools, and a chandelier.
A grand lobby with a bar area, ornate chandeliers, and a staircase.
A spacious lobby with a high ceiling, ornate chandeliers, and a seating area with sofas and armchairs.
A grand lobby with a large chandelier, a bar area, and classical architecture.

18. Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
Downtown St. Louis
United States
Carol
￥17,490
￥20,799 total
includes taxes & fees
Sep 27 - Sep 28
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
A spacious lobby with high arched ceilings, ornate columns, and a central fountain.
A multi-level hotel lobby with a grand staircase, a reception desk, and a seating area.
A spacious lobby with high ceilings, ornate green and gold detailing, and a central bar area.
A spacious lobby with a high arched ceiling, multiple seating areas, and a central decorative column.

19. St. Louis Union Station Hotel, Curio Collection by Hilton

St. Louis Union Station Hotel, Curio Collection by Hilton
Downtown West
United States
Mirjana
￥29,813
￥35,455 total
includes taxes & fees
Oct 23 - Oct 24
St. Louis Union Station Hotel, Curio Collection by Hilton
A modern dining area with multiple tables and chairs, large windows with a city view, and contemporary lighting fixtures.
A grand lobby with a high ceiling, ornate chandeliers, and a central seating area with blue upholstered chairs.
A rooftop pool area with lounge chairs and a clear view of the city skyline.
A hotel room with a sofa, a round table with a tray, a black dresser, and a large window with a view of a building.

20. Hotel Saint Louis, Autograph Collection

Hotel Saint Louis, Autograph Collection
Downtown St. Louis
United States
Ryan
￥26,580
￥31,612 total
includes taxes & fees
Sep 27 - Sep 28
Hotel Saint Louis, Autograph Collection
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Explore similar 5-star hotels

Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Northeast Missouri.
The Ritz-Carlton, St. Louis

The Ritz-Carlton, St. Louis

100 Carondelet Plaza St. Louis MO
￥97,356
￥113,652 total
Oct 26 - Oct 27
includes taxes & fees
9.2/10 Wonderful! (586 reviews)
The Ritz-Carlton, St. Louis
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Northeast Missouri

Great live music, sports teams, and popular sights from St. Louis Zoo to St. Louis Union Station—explore Northeast Missouri, a family-friendly destination also known for its theaters.

See all hotels in Northeast Missouri
A large eye sculpture in a park surrounded by trees.
Photo by Andrew Hershfeld

Top Northeast Missouri Hotel Reviews

The Cheshire

The Cheshire

10/10 Excellent
"Just stayed one night with my husband but we want to come back. Good location, loved the British theme going, breakfast was excellent, fun exploring all the floors in the hotel as it has 4 floors. Did not visit the restaurants but I bet they were good and they gave us a coupon to user but we did not as we checked in late. Our room was quiet on the first floor. Good parking available. Staff were friendly and helpful during our whole stay. Loved the room author thing going on and labels on doors as it was fun to read, lots of good artwork, loved the author of your room having a book in the room like ours was Ann Sewell who wrote Black Beauty and we had a paper back copy of it in our room. If I was to ask for anything , it would be a small refrigerator as my husband travels with meds and a grab bar to step out of the tub. Would highly recommend."
Dixie 1-night trip
Posted 11 hours ago
The Cheshire
Renaissance St. Louis Airport Hotel

Renaissance St. Louis Airport Hotel

10/10 Excellent
"Will definitely book again through them. Great price for the time I stayed and close to everything"
Emily 2-night trip
Posted 1 day ago
Renaissance St. Louis Airport Hotel
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

8/10 Good
"Excellent roof top bar!!!"
michelle 1-night trip
Posted 2 days ago
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
Live by Loews - St.Louis

Live by Loews - St.Louis

10/10 Excellent
"Amazing. Such a great atmosphere!"
Suzanne 1-night trip
Posted 2 days ago
Live by Loews - St.Louis

Frequently asked questions

What are the best 4-star hotels in Northeast Missouri?
You can find a variety of 4-star hotels in Northeast Missouri, including in St. Louis. St. Louis Union Station Hotel, Curio Collection by Hilton is an Expedia customer favorite here that offers premium bedding and concierge services. Another place that rates highly with travelers is The Last Hotel. Concierge services and a pillowtop mattress help make it their preferred choice.
How much does it cost to stay in a 4-star hotel in Northeast Missouri?
We can help you quickly locate the ideal 4-star hotel for your trip to Northeast Missouri. Use our filter tool to fine-tune your search by things like amenities, budget and star rating and get access to unbeatable deals in a couple of clicks.
  • Search for the lowest price from ￥113,652
What's the difference between 5-star and 4-star hotels in Northeast Missouri?
Give yourself the luxury treatment during your Northeast Missouri escape by checking in to a 4-star hotel. As well as featuring upscale accommodations, these properties are typically filled with amenities like large beds, complimentary bathrobes and more. A 5-star hotel will go the extra mile to make your trip an even more indulgent and unforgettable one. 24-hour front desk, luxurious spas and world-class dining are only the start of the exclusive services and conveniences you'll likely be able to enjoy.

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