Find all hotels by Independent in Upstate South Carolina, SC
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
Check prices for these dates
Tonight
Sep 9 - Sep 10Tomorrow
Sep 10 - Sep 11This weekend
Sep 11 - Sep 13Next weekend
Sep 18 - Sep 20
Save an average of 15% on thousands of hotels when you're signed in
Top Upstate South Carolina Hotel Reviews
Lakeside Lodge Clemson
10/10 Excellent
"Always amazing"
Grand Bohemian Lodge Greenville, Autograph Collection
10/10 Excellent
"Staff is friendly and very professional. I loved the location and the city very much!"
Holiday Inn Express Hotel & Suites Spartanburg-North by IHG
10/10 Excellent
"I’m"
Hyatt Place Greenville Downtown
10/10 Excellent
"Staff great, location great."
Hilton Greenville
10/10 Excellent
"Faster elevators"
Embassy Suites Greenville Golf Resort & Conference Center
10/10 Excellent
"Always love going there since they opened decades ago. Love it. Going back soon !"
Hyatt Regency Greenville
10/10 Excellent
"Great location"
Mint House Greenville Downtown by Kasa
10/10 Excellent
"Felt like our own little apartment! It was clean and loved the safety features"
Best Western Plus Clemson Hotel & Conference Center
10/10 Excellent
"Very good breakfast and area! Good staff and clean rooms! Loved it!"
Explore a world of travel with Expedia
- B&B in Welcome
- Sans Souci Hotels
- Aparthotels in Lando
- Rv Parks in York
- Rv Parks in Prosperity
- Clemson Hotels
- All-Inclusive Hotel Hotels in Greenville Downtown
- Historic Hotels in Anderson
- Travelers Rest Hotels
- Cheap Hotels in Greenville Downtown
- Rv Parks in Spartanburg County
- Cheap Hotels in Simpsonville
- B&B in Seneca
- Ski Hotels in Upstate South Carolina
- Inns in Woodruff
- Villas in Sunset
- Hotels near Spartanburg Memorial Auditorium
- Hostels in Greer
- Fountain Inn Hotels
- Hotels near Clemson University
- Rv Parks in Liberty
- Hotels near Lake Jocassee
- Clover Hotels
- Hotel with a Concierge Hotels in Greenville Downtown
- Aparthotels in Clemson
- Spartanburg County Hotels
- Hostels in Greenwood
- Anderson Hotels
- Aparthotels in Central
- Greenville Hotels
- Hotels with Early Check-in in Spartanburg
- Pomaria Hotels
- Hotels near Greenville Station
- B&B in Blacksburg
- Hotels near Falls Park on the Reedy
- Farmstay in Fountain Inn
- Hotel with a Concierge Hotels in Greenville - Spartanburg
- Luxury Hotels in Sandy Springs
- Hotels near Fred W. Symmes Chapel
- Guest Houses in Fountain Inn
- Hotels near Greenville Downtown
- Guest Houses in Gantt
- Resorts & Hotels with Spas in Upstate South Carolina
- Aparthotels in Sunset
- Rv Parks in Pendleton
- Union Hotels
- Inns in Clemson
- Hostels in York
- Adults Only Resorts & in Seneca
- B&B in Lowndesville
- Resorts in Newport
- Beach Hotels in Sunset
- Hotels near Donaldson Center
- Aparthotels in Sans Souci
- Duncan Hotels
- Rv Parks in Upstate South Carolina
- Luxury Hotels in Greenville Downtown
- B&B in Greenville - Spartanburg
- Hotels with Hot Tubs in Cleveland
- Sandy Springs Hotels
- B&B in Sunset
- Cheap Hotels in Carlisle
- Laurens Hotels
- Luxury Hotels in Simpsonville
- Berea Hotels
- Cabin Rentals in Welcome
- Greenville Downtown Hotels
- Mauldin Hotels
- Aparthotels in Welcome
- Resorts in Clemson
- Aparthotels in Clover
- Hotels with WiFi in Spartanburg
- Resorts in Travelers Rest
- Greer Hotels
- B&B in Belton
- Cheap Hotels in Greenville
- Cheap Hotels in Blackstock
- Rv Parks in Greenville County
- Hotels near Greenville-Spartanburg Intl.
- B&B in Carlisle
- Inns in Easley
- All-Inclusive Hotel Hotels in Greenville
- Hotels near Bob Jones University
- Hotels near Rock Hill-York County
- Villas in Iva
- Cheap Hotels in Spartanburg County
- Spartanburg Hotels
- Resorts in Sunset
- Apartments in Duncan
- Apartments in Welcome
- Golden Grove Hotels
- Waterpark Hotels in Greenville