Top Siesta Isle Hotels

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Our top choices for Siesta Isle hotels

A row of turquoise Adirondack chairs with umbrellas, a wooden deck, and a marina in the background.

1. Latitude 26 Waterfront Boutique Resort - Fort Myers Beach

Siesta Isle

Jennifer

￥14,179 total

includes taxes & fees

Sep 16 - Sep 17

A balcony with a wicker sofa, a yellow table, and a potted plant.

2. Latitude 26 Waterfront Resort & Marina

1.1 km from Siesta Isle

Sebastian

￥15,864 total

includes taxes & fees

Sep 17 - Sep 18

An outdoor patio with tables and chairs, umbrellas, and a pool in the background.

3. Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG

2.7 km from Siesta Isle

Kenton Sean

￥16,271 total

includes taxes & fees

Oct 13 - Oct 14

A spacious lobby with a high ceiling, a seating area with a sofa and chairs, a small round table, and a decorative wall with artwork.

4. Hampton Inn & Suites Fort Myers Beach/Sanibel Gateway

2.6 km from Siesta Isle

Jason

￥13,200 total

includes taxes & fees

Sep 23 - Sep 24

A hotel pool area with multiple lounge chairs and umbrellas, surrounded by a fence and palm trees.

5. La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway

2.3 km from Siesta Isle

Jorge

￥13,702 total

includes taxes & fees

Sep 23 - Sep 24

A swimming pool with a rock arch structure, a multi-story building with balconies, and palm trees in the background.

6. Pink Shell Beach Resort and Marina

1.8 km from Siesta Isle

David

￥44,730 total

includes taxes & fees

Sep 28 - Sep 29

A large, clear swimming pool with multiple lounge areas and palm trees.

7. Margaritaville Beach Resort Fort Myers

2.6 km from Siesta Isle

Idelio

￥34,576 total

includes taxes & fees

Oct 5 - Oct 6

A spacious dining area with multiple tables and chairs, large windows, and a modern chandelier.

8. Residence Inn by Marriott Fort Myers Sanibel

2.7 km from Siesta Isle

James

￥15,415 total

includes taxes & fees

Sep 23 - Sep 24

A modern dining area with wooden flooring, white chairs, and large windows offering a view of the beach.

9. Best Western Plus Beach Resort

2.2 km from Siesta Isle

selma

￥29,776 total

includes taxes & fees

Sep 28 - Sep 29

A beach view from a balcony with a pool, palm trees, and a building with a balcony.

10. Edison Beach House

2.3 km from Siesta Isle

Gayle

￥30,272 total

includes taxes & fees

Sep 20 - Sep 21

A beach view with rows of empty wine glasses lined up on a balcony.

11. Lani Kai Beachfront Resort

2.7 km from Siesta Isle

ROBERT

￥26,649 total

includes taxes & fees

Sep 30 - Oct 1

A swimming pool with lounge chairs and umbrellas, surrounded by palm trees and a stone archway.

12. The Lighthouse Resort Inn & Suites

2.4 km from Siesta Isle

Sherrie

￥18,606 total

includes taxes & fees

Sep 20 - Sep 21

A Holiday Inn Express building with a modern design, featuring a flat facade and a covered entrance area.

13. Holiday Inn Express & Suites Fort Myers Airport by IHG

17.9 km from Siesta Isle

Brandon

￥17,371 total

includes taxes & fees

Sep 21 - Sep 22

An outdoor patio with yellow chairs and red umbrellas, a fire pit, and a modern building in the background.

14. Home2 Suites by Hilton Fort Myers Airport

17.5 km from Siesta Isle

Elio

￥18,820 total

includes taxes & fees

Sep 27 - Sep 28

A modern hotel lobby with wooden flooring, blue and beige chairs, and a patterned rug.

15. Hampton Inn Fort Myers-Airport & I-75

17.4 km from Siesta Isle

John

￥12,500 total

includes taxes & fees

Oct 5 - Oct 6

A hotel room with a large bed, two bedside tables with lamps, a nightstand, and a window with curtains.

16. Candlewood Suites Fort Myers Sanibel Gateway by IHG

4.9 km from Siesta Isle

John

￥8,943 total

includes taxes & fees

Sep 20 - Sep 21

A beachfront hotel with a pool, beach, and ocean view.

17. DiamondHead Beach Resort

2.9 km from Siesta Isle

Kristina

￥41,294 total

includes taxes & fees

Sep 16 - Sep 17

A hotel reception area with a curved reception desk, potted plants, and a large window with a view.

18. Americas Best Value Inn Ft. Myers

13.7 km from Siesta Isle

Brandon

￥11,485 total

includes taxes & fees

Sep 23 - Sep 24

A spacious lobby with a staircase, seating area, and a large wall-mounted screen.

19. Days Inn & Suites by Wyndham Fort Myers Near JetBlue Park

18.4 km from Siesta Isle

Renny

￥11,253 total

includes taxes & fees

Sep 19 - Sep 20

An outdoor patio with wicker furniture, a fire feature, and string lights.

20. Hilton Garden Inn Ft Myers

11.7 km from Siesta Isle

Gina

￥16,306 total

includes taxes & fees

Sep 24 - Sep 25

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Where to stay in Siesta Isle

Find the best Siesta Isle areas and neighborhoods for the activities you enjoy most.

A sunset over a calm sea with trees framing the view.

Mid Island

While visiting Mid Island, you might make a stop by sights like Estero Boulevard Beach and Sterling Ave Beach.

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A pier extending into the water with two gazebos at the end, under a sunset sky.

South Island

While visiting South Island, you might make a stop by sights like Santini Marina Shopping Plaza and Castle Beach.

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A coastal town with a marina, residential buildings, and a clear view of the ocean.

TP Hill's

When in TP Hill's, you can plan a visit to Key West Express and Estero Boulevard Beach, some noteworthy sights in the nearby area.

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A beach with a wooden pier, people sunbathing, and a clear blue sky.

Downtown Fort Myers Beach

If you're spending some time in Downtown Fort Myers Beach, Lynn Hall Memorial Park and Estero Boulevard Beach are top sights worth seeing.

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A coastal town with a beach, buildings, and a road.

Winklers

While Winklers might not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Key West Express and Estero Boulevard Beach.

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Top Siesta Isle Hotel Reviews

Lani Kai Beachfront Resort

10/10 Excellent

"Fantastic location. The staff is amazing."

Latitude 26 Waterfront Boutique Resort - Fort Myers Beach

10/10 Excellent

"We absolutely loved this quaint little motel in Fort Myers, Florida. The rooms were clean and comfortable as well as cutely decorated. They had nice plates and cups to use as well. The grounds of the motel were wonderful. Lots of places to hang out and enjoy the outdoors. The pool was clean and they had floats and toys to use. Mallory at the front desk was very friendly and helpful with dinner and shelling recommendations. Great stay overall, highly recommend!"

Frequently asked questions

What is Siesta Isle like?

Travelers will be sure to find plenty to entertain them in Fort Myers Beach's Siesta Isle neighborhood. Consider a visit to San Carlos Bay - Bunche Beach Preserve as part of your Siesta Isle travel plans.

Where is the best place to stay in Siesta Isle?

Based on our traveler data, Latitude 26 Waterfront Boutique Resort - Fort Myers Beach is one of the top choices for your stay in Siesta Isle. This hotel offers a marina and free breakfast.

How many hotels will I find in Siesta Isle?

If you're searching for places to stay in Fort Myers Beach, Expedia has something to meet your needs with 27 Siesta Isle hotels and other accommodations to choose from.

If I need to cancel my hotel reservation in Siesta Isle, will I receive a refund?

Yes, you'll find most room reservations are refundable provided that you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your arrival date. If you have a non-refundable reservation, you might still have the option to cancel and be given a refund within a 24-hour period of your booking. Add your dates and click on "Search", then use the "fully refundable" filter to view the top deals on offer in Siesta Isle.

Where can I learn more about changing or cancelling my trip to Siesta Isle?

To access more information about picking new dates or cancelling your trip to Siesta Isle, head over to our customer service page.

What are the top things to see and do in Siesta Isle?

San Carlos Bay - Bunche Beach Preserve is an attraction you might want to check out while you're in Siesta Isle. Key West Express and Bunche Beach are also worth a visit when you're out sightseeing in Fort Myers Beach.

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Our top choices for Siesta Isle hotels

1. Latitude 26 Waterfront Boutique Resort - Fort Myers Beach

2. Latitude 26 Waterfront Resort & Marina

3. Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG

4. Hampton Inn & Suites Fort Myers Beach/Sanibel Gateway

5. La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway

6. Pink Shell Beach Resort and Marina

7. Margaritaville Beach Resort Fort Myers

8. Residence Inn by Marriott Fort Myers Sanibel

9. Best Western Plus Beach Resort

10. Edison Beach House

11. Lani Kai Beachfront Resort

12. The Lighthouse Resort Inn & Suites

13. Holiday Inn Express & Suites Fort Myers Airport by IHG

14. Home2 Suites by Hilton Fort Myers Airport

15. Hampton Inn Fort Myers-Airport & I-75

16. Candlewood Suites Fort Myers Sanibel Gateway by IHG

17. DiamondHead Beach Resort

18. Americas Best Value Inn Ft. Myers

19. Days Inn & Suites by Wyndham Fort Myers Near JetBlue Park

20. Hilton Garden Inn Ft Myers

Where to stay in Siesta Isle

Mid Island

South Island

TP Hill's

Downtown Fort Myers Beach

Winklers

Top Siesta Isle Hotel Reviews

Lani Kai Beachfront Resort

Frequently asked questions

Explore a world of travel with Expedia