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Our top choices for Siesta Isle hotels

Latitude 26 Waterfront Boutique Resort - Fort Myers Beach

Latitude 26 Waterfront Boutique Resort - Fort Myers Beach
2.5 star property
Siesta Isle
8.8 out of 10, Excellent, (1,001 reviews)
"Great stay"
United States
Andrea
The price is ¥46,103
¥51,404 total
includes taxes & fees
Mar 19 - Mar 20
Latitude 26 Waterfront Boutique Resort - Fort Myers Beach

Lani Kai Beachfront Resort

Lani Kai Beachfront Resort
3.5 star property
2.7 km from Siesta Isle
9.0 out of 10, Wonderful, (1,300 reviews)
"Nice place to stay"
United States
Denise
The price is ¥42,148
¥50,522 total
includes taxes & fees
Mar 24 - Mar 25
Lani Kai Beachfront Resort

Shangri-La Springs

Shangri-La Springs
2.5 star property
23.4 km from Siesta Isle
9.2 out of 10, Wonderful, (202 reviews)
"Enjoyed our stay. Very nice "
United States
Elizabeth
Shangri-La Springs

The Anchor Inn

The Anchor Inn
2.0 star property
9.7 km from Siesta Isle
9.8 out of 10, Exceptional, (6 reviews)
"This hotel was perfect It was decorated beautifully and was so clean and the bed was so comfy and the rainfall shower was very nice, the room had everything you could need for a nice vacation there’s a market within walking distance which had everything you need to make your stay perfect highly recommend this hotel anytime we come back to Sanibel we will always stay here "
United States
Mary
The price is ¥42,432
¥49,684 total
includes taxes & fees
Mar 22 - Mar 23
The Anchor Inn

MainStay Suites Fort Myers East I-75

MainStay Suites Fort Myers East I-75
2.5 star property
25.4 km from Siesta Isle
9.6 out of 10, Exceptional, (310 reviews)
"Large rooms, great rates, great breakfast and a convenient location. "
Canada
Fraser
The price is ¥26,215
¥29,230 total
includes taxes & fees
Apr 9 - Apr 10
MainStay Suites Fort Myers East I-75

Park Motel

Park Motel
2.5 star property
24.7 km from Siesta Isle
9.4 out of 10, Exceptional, (38 reviews)
"Clean, quiet, very friendly and helpful staff, hot tub in room very relaxing."
United States
Kristeen
The price is ¥13,285
¥14,812 total
includes taxes & fees
Apr 1 - Apr 2
Park Motel

Fairways Inn of Naples

Fairways Inn of Naples
3.0 star property
28.6 km from Siesta Isle
9.4 out of 10, Exceptional, (1,229 reviews)
"Clean room and staff was very friendly."
United States
shera
The price is ¥18,413
¥20,438 total
includes taxes & fees
Apr 7 - Apr 8
Fairways Inn of Naples

TownePlace Suites by Marriott Fort Myers Gulf Coast

TownePlace Suites by Marriott Fort Myers Gulf Coast
3.0 star property
15.9 km from Siesta Isle
9.2 out of 10, Wonderful, (159 reviews)
"Everything about the stay in was beautiful "
United States
Jameasha
The price is ¥26,836
¥29,922 total
includes taxes & fees
Apr 7 - Apr 8
TownePlace Suites by Marriott Fort Myers Gulf Coast

Comfort Suites Fort Myers East I-75

Comfort Suites Fort Myers East I-75
2.5 star property
25.5 km from Siesta Isle
9.6 out of 10, Exceptional, (425 reviews)
"Good hotel for the price "
United Kingdom
Paul
The price is ¥21,375
¥23,833 total
includes taxes & fees
Apr 3 - Apr 4
Comfort Suites Fort Myers East I-75

Woodspring Suites Fort Myers - Cape Coral

Woodspring Suites Fort Myers - Cape Coral
2.5 star property
15.9 km from Siesta Isle
7.4 out of 10, Good, (233 reviews)
"The room was new, high quality and staff was excellent!"
United States
Brian
The price is ¥14,839
¥16,546 total
includes taxes & fees
Mar 17 - Mar 18
Woodspring Suites Fort Myers - Cape Coral

Latitude 26 Waterfront Boutique Resort - Bonita Springs

Latitude 26 Waterfront Boutique Resort - Bonita Springs
3.0 star property
20.4 km from Siesta Isle
8.8 out of 10, Excellent, (737 reviews)
"Adorable place and great spot near the beach. Enjoyed our stay amd look forward to coming back. "
United States
Michelle
Latitude 26 Waterfront Boutique Resort - Bonita Springs

The Perry Hotel Naples

The Perry Hotel Naples
4.5 star property
26.4 km from Siesta Isle
9.6 out of 10, Exceptional, (685 reviews)
"Friendly, helpful staff Great location excellent restaurant"
United States
Alan
The price is ¥50,485
¥63,938 total
includes taxes & fees
Mar 21 - Mar 22
The Perry Hotel Naples

Casa Ybel Resort

Casa Ybel Resort
2.5 star property
12.8 km from Siesta Isle
8.8 out of 10, Excellent, (311 reviews)
"Clean rooms, great staff, beautiful view "
United States
Julia
The price is ¥93,156
¥103,870 total
includes taxes & fees
Apr 10 - Apr 11
Casa Ybel Resort

Angler's Inn

Angler's Inn
2.5 star property
20.5 km from Siesta Isle
9.4 out of 10, Exceptional, (327 reviews)
"Cute Inn in Matlacha. Clean rooms, comfy beds, and a great screened in porch for each room. Town still recovering from Ian, but still a great time. "
United States
Crystal
The price is ¥27,626
¥44,885 total
includes taxes & fees
Mar 14 - Mar 15
Angler's Inn

Matlacha on Shoreview

Matlacha on Shoreview
2.0 star property
21.1 km from Siesta Isle
9.6 out of 10, Exceptional, (240 reviews)
"Beautiful resort, great communication, super clean "
United States
Ronald
The price is ¥15,628
¥27,987 total
includes taxes & fees
Mar 18 - Mar 19
Matlacha on Shoreview

Shalimar Beach Resort

Shalimar Beach Resort
2.0 star property
14.4 km from Siesta Isle
10.0 out of 10, Exceptional, (33 reviews)
"Everything about this place was great "
United States
Andrew
The price is ¥88,109
¥98,242 total
includes taxes & fees
Mar 12 - Mar 13
Shalimar Beach Resort

Days Inn & Suites by Wyndham Bonita Springs North Naples

Days Inn & Suites by Wyndham Bonita Springs North Naples
2.5 star property
25.6 km from Siesta Isle
7.8 out of 10, Good, (1,013 reviews)
"The place to sleep was great, everything was clean when we arrived and very comfortable."
United States
Romeo
The price is ¥15,628
¥17,426 total
includes taxes & fees
Apr 7 - Apr 8
Days Inn & Suites by Wyndham Bonita Springs North Naples

Quality Inn Fort Myers Cape Coral

Quality Inn Fort Myers Cape Coral
2.0 star property
15.3 km from Siesta Isle
7.4 out of 10, Good, (241 reviews)
"Clean room and staff was excellent "
Canada
SURINDER
The price is ¥12,912
¥16,693 total
includes taxes & fees
Apr 5 - Apr 6
Quality Inn Fort Myers Cape Coral

Comfort Inn Fort Myers Northeast

Comfort Inn Fort Myers Northeast
2.5 star property
28.1 km from Siesta Isle
7.8 out of 10, Good, (696 reviews)
"Nice stay"
United States
Carole
The price is ¥14,512
¥16,180 total
includes taxes & fees
Apr 5 - Apr 6
Comfort Inn Fort Myers Northeast

Hampton Inn Fort Myers-Airport & I-75

Hampton Inn Fort Myers-Airport & I-75
3.5 star property
17.4 km from Siesta Isle
9.0 out of 10, Wonderful, (1,000 reviews)
"Great location, room, breakfast and value for the money"
United States
Joel
The price is ¥18,162
¥20,249 total
includes taxes & fees
Apr 2 - Apr 3
Hampton Inn Fort Myers-Airport & I-75
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Siesta Isle

Find the best Siesta Isle areas and neighborhoods for the activities you enjoy most.

Mid Island

While visiting Mid Island, you might make a stop by sights like Estero Boulevard Beach and Sterling Ave Beach.

South Island

While visiting South Island, you might make a stop by sights like Santini Marina Shopping Plaza and Castle Beach.

TP Hill's

When in TP Hill's, you can plan a visit to Key West Express and Estero Boulevard Beach, some noteworthy sights in the nearby area.

Downtown Fort Myers Beach

If you're spending some time in Downtown Fort Myers Beach, Lynn Hall Memorial Park and Estero Boulevard Beach are top sights worth seeing.

Laguna Shores

Though Laguna Shores might not have many top sights, you can venture to the surrounding area to see attractions like Lover's Key Beach and Santini Marina Shopping Plaza.

Top Siesta Isle Hotel Reviews

Frequently asked questions

What is Siesta Isle like?
Travelers will be sure to find plenty to entertain them in Fort Myers Beach's Siesta Isle neighborhood. Consider a visit to San Carlos Bay - Bunche Beach Preserve as part of your Siesta Isle travel plans.
Where is the best place to stay in Siesta Isle?
Based on Expedia customer reviews, Latitude 26 Waterfront Boutique Resort - Fort Myers Beach is the highest ranked property in Siesta Isle. This hotel offers a marina and free breakfast.
How many hotels will I find in Siesta Isle?
When you want to kick up your feet after a day of exploring the sights in Fort Myers Beach, you can choose from 18 Expedia hotels and other accommodations in Siesta Isle.
If I need to cancel my hotel reservation in Siesta Isle, will I receive a refund?
Yes, you'll find most room reservations are refundable provided that you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your arrival date. If you have a non-refundable reservation, you might still have the option to cancel and be given a refund within a 24-hour period of your booking. Add your dates and click on "Search", then use the "fully refundable" filter to view the top deals on offer in Siesta Isle.
Where can I learn more about changing or cancelling my trip to Siesta Isle?
To access more information about picking new dates or cancelling your trip to Siesta Isle, head over to our customer service page.
What are the top things to see and do in Siesta Isle?
San Carlos Bay - Bunche Beach Preserve is an attraction you might want to check out while you're in Siesta Isle. Key West Express and Bunche Beach are also worth a visit when you're out sightseeing in Fort Myers Beach.