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Oct 30 - Nov 1
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Nov 6 - Nov 8

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Our top choices for Siesta Isle hotels

A row of turquoise Adirondack chairs with umbrellas, a wooden deck, and a marina in the background.

1. Latitude 26 Waterfront Boutique Resort - Fort Myers Beach

Latitude 26 Waterfront Boutique Resort - Fort Myers Beach
2.5 star property
Siesta Isle
9.0 out of 10, Wonderful, (1,003 reviews)
"I like this hotel we have been twice"
United States
Giovanna
The price is ￥14,106
￥15,728 total
includes taxes & fees
Oct 25 - Oct 26
Latitude 26 Waterfront Boutique Resort - Fort Myers Beach
A large, clear swimming pool with multiple lounge areas and palm trees.

2. Margaritaville Beach Resort Fort Myers

Margaritaville Beach Resort Fort Myers
4.0 star property
2.6 km from Siesta Isle
9.0 out of 10, Wonderful, (2,692 reviews)
"Our favorite place to stay."
United States
Anastasia
The price is ￥26,199
￥37,076 total
includes taxes & fees
Oct 25 - Oct 26
Margaritaville Beach Resort Fort Myers
A swimming pool with a rock arch structure, a multi-story building with balconies, and palm trees in the background.

3. Pink Shell Beach Resort and Marina

Pink Shell Beach Resort and Marina
4.0 star property
1.8 km from Siesta Isle
9.4 out of 10, Exceptional, (1,481 reviews)
"It's nice place to stay"
United States
Mario
The price is ￥33,743
￥47,944 total
includes taxes & fees
Nov 15 - Nov 16
Pink Shell Beach Resort and Marina
A modern dining area with wooden flooring, white chairs, and large windows offering a view of the beach.

4. Best Western Plus Beach Resort

Best Western Plus Beach Resort
2.5 star property
2.2 km from Siesta Isle
9.4 out of 10, Exceptional, (1,002 reviews)
"Convenient location, friendly staff and clean rooms."
United States
Stacy
The price is ￥33,954
￥37,859 total
includes taxes & fees
Nov 8 - Nov 9
Best Western Plus Beach Resort
An outdoor patio with tables and chairs, umbrellas, and a pool in the background.

5. Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG

Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG
2.5 star property
2.7 km from Siesta Isle
9.2 out of 10, Wonderful, (1,000 reviews)
"Clean Hotel! Convenient for one night stay, close to airport and beaches."
United States
Kimberly
The price is ￥13,636
￥15,204 total
includes taxes & fees
Oct 29 - Oct 30
Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG
A spacious lobby with a high ceiling, a seating area with a sofa and chairs, a small round table, and a decorative wall with artwork.

6. Hampton Inn & Suites Fort Myers Beach/Sanibel Gateway

Hampton Inn & Suites Fort Myers Beach/Sanibel Gateway
3.0 star property
2.6 km from Siesta Isle
8.8 out of 10, Excellent, (1,002 reviews)
"One of the best properties I’ve stayed in and the staff were excellent."
United States
Christina
The price is ￥13,566
￥15,126 total
includes taxes & fees
Oct 29 - Oct 30
Hampton Inn & Suites Fort Myers Beach/Sanibel Gateway
A spacious dining area with multiple tables and chairs, large windows, and a modern chandelier.

7. Residence Inn by Marriott Fort Myers Sanibel

Residence Inn by Marriott Fort Myers Sanibel
3.0 star property
2.7 km from Siesta Isle
8.8 out of 10, Excellent, (1,003 reviews)
"The hotel was in a great location, very clean and had great breakfast options."
United States
jennifer
The price is ￥14,733
￥16,427 total
includes taxes & fees
Nov 16 - Nov 17
Residence Inn by Marriott Fort Myers Sanibel
A hotel pool area with multiple lounge chairs and umbrellas, surrounded by a fence and palm trees.

8. La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway

La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway
3.0 star property
2.3 km from Siesta Isle
8.2 out of 10, Very good, (1,393 reviews)
"The staff was very helpful during my stay."
United States
Samantha
The price is ￥11,922
￥13,293 total
includes taxes & fees
Nov 1 - Nov 2
La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway
A swimming pool with lounge chairs and umbrellas, surrounded by palm trees and a stone archway.

9. The Lighthouse Resort Inn & Suites

The Lighthouse Resort Inn & Suites
3.0 star property
2.4 km from Siesta Isle
8.6 out of 10, Excellent, (1,833 reviews)
"excellent place to stay"
United States
Shayne
The price is ￥18,196
￥23,423 total
includes taxes & fees
Nov 10 - Nov 11
The Lighthouse Resort Inn & Suites
A beach view from a balcony with a pool, palm trees, and a building with a balcony.

10. Edison Beach House

Edison Beach House
3.5 star property
2.3 km from Siesta Isle
9.4 out of 10, Exceptional, (1,952 reviews)
"Great stay."
United States
Angie
The price is ￥23,698
￥32,541 total
includes taxes & fees
Oct 25 - Oct 26
Edison Beach House
A wooden deck with outdoor seating, a thatched-roof structure, and string lights.

11. Latitude 26 Waterfront Resort & Marina

Latitude 26 Waterfront Resort & Marina
3.0 star property
1.1 km from Siesta Isle
8.6 out of 10, Excellent, (1,000 reviews)
"Great place to stay, especially on a fishing trip!"
United States
Mitchel
The price is ￥13,948
￥15,552 total
includes taxes & fees
Oct 25 - Oct 26
Latitude 26 Waterfront Resort & Marina
A beachfront hotel with a pool, beach, and ocean view.

12. DiamondHead Beach Resort

DiamondHead Beach Resort
3.5 star property
2.9 km from Siesta Isle
9.2 out of 10, Wonderful, (1,319 reviews)
"excellent place will stay again!"
United States
James Edward
The price is ￥28,054
￥37,397 total
includes taxes & fees
Oct 25 - Oct 26
DiamondHead Beach Resort
A balcony with two blue lounge chairs and a small table, overlooking a beach with palm trees and the ocean.

13. Lani Kai Beachfront Resort

Lani Kai Beachfront Resort
3.5 star property
2.7 km from Siesta Isle
8.8 out of 10, Excellent, (2,142 reviews)
"It was great to be right on the beach! The restaurants were also good."
United States
Tanya
The price is ￥23,176
￥29,336 total
includes taxes & fees
Nov 3 - Nov 4
Lani Kai Beachfront Resort
A marina with boats docked, surrounded by palm trees and a building with a red-tiled roof.

14. Matanzas Inn Bayside Resort and Marina

Matanzas Inn Bayside Resort and Marina
3.0 star property
2.1 km from Siesta Isle
9.4 out of 10, Exceptional, (1,000 reviews)
"I love Matanza. It's in a great location, walking distance to everything. I enjoyed sitting on the canal/bay and seeing all the wildlife, especially Manatee! We stayed in the 2 bedroom and it was perfect!"
United States
Tammy
The price is ￥25,573
￥32,436 total
includes taxes & fees
Oct 27 - Oct 28
Matanzas Inn Bayside Resort and Marina
A balcony with tables set for dining, overlooking a beach with palm trees and the ocean.

15. The Bay Inn at Lani Kai

The Bay Inn at Lani Kai
3.0 star property
2.7 km from Siesta Isle
7.8 out of 10, Good, (531 reviews)
"Clean room, helpful staff, very close to the beach."
United States
Andrea
The price is ￥16,786
￥22,211 total
includes taxes & fees
Nov 16 - Nov 17
The Bay Inn at Lani Kai
A hotel with a modern facade, palm trees, and a clear blue sky.

16. Candlewood Suites Fort Myers Sanibel Gateway by IHG

Candlewood Suites Fort Myers Sanibel Gateway by IHG
3.0 star property
4.9 km from Siesta Isle
7.6 out of 10, Good, (1,000 reviews)
"I was satisfied with the price for a short stay."
United States
James
The price is ￥11,138
￥12,419 total
includes taxes & fees
Nov 1 - Nov 2
Candlewood Suites Fort Myers Sanibel Gateway by IHG
A hotel room with two beds, a wooden headboard, a nightstand with a lamp, and a window with curtains.

17. Holiday Inn Express Cape Coral-Fort Myers Area by IHG

Holiday Inn Express Cape Coral-Fort Myers Area by IHG
2.5 star property
9.7 km from Siesta Isle
9.4 out of 10, Exceptional, (1,724 reviews)
"Excellent hotel if you want to stay there for a few days"
United States
Gabriel
The price is ￥15,844
￥17,666 total
includes taxes & fees
Oct 28 - Oct 29
Holiday Inn Express Cape Coral-Fort Myers Area by IHG
A balcony with a table and chairs, large windows, and a view of the sea.

18. The Westin Cape Coral Resort At Marina Village

The Westin Cape Coral Resort At Marina Village
4.0 star property
8.3 km from Siesta Isle
9.0 out of 10, Wonderful, (1,000 reviews)
"Very clean and nice place!"
United States
Charles
The price is ￥21,504
￥30,973 total
includes taxes & fees
Nov 22 - Nov 23
The Westin Cape Coral Resort At Marina Village
An indoor swimming pool with clear water, a lifeguard station, and a seating area with chairs.

19. Comfort Inn & Suites Fort Myers Airport

Comfort Inn & Suites Fort Myers Airport
2.5 star property
18.1 km from Siesta Isle
8.6 out of 10, Excellent, (1,163 reviews)
"The breakfast was amazing"
United States
Erika
The price is ￥11,861
￥13,226 total
includes taxes & fees
Nov 22 - Nov 23
Comfort Inn & Suites Fort Myers Airport
A modern kitchen with a central island, overhead lighting, and a chalkboard menu.

20. Homewood Suites by Hilton Fort Myers Airport/FGCU

Homewood Suites by Hilton Fort Myers Airport/FGCU
3.0 star property
17 km from Siesta Isle
9.4 out of 10, Exceptional, (1,002 reviews)
"Great property good location friendly staff very clean room good breakfast"
United States
Leo
The price is ￥19,334
￥21,557 total
includes taxes & fees
Nov 1 - Nov 2
Homewood Suites by Hilton Fort Myers Airport/FGCU
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare popular hotels in Siesta Isle

Property
Star rating
Guest rating
Breakfast included
Pool
Spa
Pet friendly
WiFi included
A row of turquoise Adirondack chairs with umbrellas, a wooden deck, and a marina in the background.
Latitude 26 Waterfront Boutique Resort - Fort Myers Beach
2.5 star property
9.0
Wonderful
1,003 reviews
View
A modern dining area with wooden flooring, white chairs, and large windows offering a view of the beach.
Best Western Plus Beach Resort
2.5 star property
9.4
Exceptional
1,002 reviews
View
A swimming pool with a rock arch structure, a multi-story building with balconies, and palm trees in the background.
Pink Shell Beach Resort and Marina
4.0 star property
9.4
Exceptional
1,481 reviews
View
A large, clear swimming pool with multiple lounge areas and palm trees.
Margaritaville Beach Resort Fort Myers
4.0 star property
9.0
Wonderful
2,692 reviews
View
An outdoor patio with tables and chairs, umbrellas, and a pool in the background.
Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG
2.5 star property
9.2
Wonderful
1,000 reviews
View

Hotels recommended for families in Siesta Isle

A row of turquoise Adirondack chairs with umbrellas, a wooden deck, and a marina in the background.

Latitude 26 Waterfront Boutique Resort - Fort Myers Beach

Latitude 26 Waterfront Boutique Resort - Fort Myers Beach
2.5 star property
Siesta Isle
9.0 out of 10, Wonderful, (1,003)
The price is ￥14,106
￥15,728 total
includes taxes & fees
Oct 25 - Oct 26
Latitude 26 Waterfront Boutique Resort - Fort Myers Beach

Where to stay in Siesta Isle

Find the best Siesta Isle areas and neighborhoods for the activities you enjoy most.
A sunset over a calm sea with trees framing the view.

Mid Island

While visiting Mid Island, you might make a stop by sights like Estero Boulevard Beach and Sterling Ave Beach.

A pier extending into the water with two gazebos at the end, under a sunset sky.

South Island

While visiting South Island, you might make a stop by sights like Santini Marina Shopping Plaza and Castle Beach.

A coastal town with a marina, residential buildings, and a clear view of the ocean.

TP Hill's

When in TP Hill's, you can plan a visit to Key West Express and Estero Boulevard Beach, some noteworthy sights in the nearby area.

A beach at sunset with a pink and purple sky, people walking, and a lifeguard tower in the distance.
Photo by Abby Chase
Open Photo by Abby Chase

Downtown Fort Myers Beach

If you're spending some time in Downtown Fort Myers Beach, Lynn Hall Memorial Park and Estero Boulevard Beach are top sights worth seeing.

A coastal town with a beach, buildings, and a road.

Winklers

While Winklers might not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Key West Express and Estero Boulevard Beach.

Top Siesta Isle Hotel Reviews

Margaritaville Beach Resort Fort Myers

Margaritaville Beach Resort Fort Myers

10/10 Excellent
"It was great!"
Robyn 1-night trip
Posted less than an hour ago
Margaritaville Beach Resort Fort Myers

Frequently asked questions

What is Siesta Isle like?
Travelers will be sure to find plenty to entertain them in Fort Myers Beach's Siesta Isle neighborhood. Consider a visit to San Carlos Bay - Bunche Beach Preserve as part of your Siesta Isle travel plans.
Where is the best place to stay in Siesta Isle?
Based on our traveler data, Latitude 26 Waterfront Boutique Resort - Fort Myers Beach is one of the top choices for your stay in Siesta Isle. This hotel offers a marina and free breakfast.
How many hotels will I find in Siesta Isle?
If you're searching for places to stay in Fort Myers Beach, Expedia has something to meet your needs with 27 Siesta Isle hotels and other accommodations to choose from.
If I need to cancel my hotel reservation in Siesta Isle, will I receive a refund?
Yes, you'll find most room reservations are refundable provided that you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your arrival date. If you have a non-refundable reservation, you might still have the option to cancel and be given a refund within a 24-hour period of your booking. Add your dates and click on "Search", then use the "fully refundable" filter to view the top deals on offer in Siesta Isle.
Where can I learn more about changing or cancelling my trip to Siesta Isle?
To access more information about picking new dates or cancelling your trip to Siesta Isle, head over to our customer service page.
What are the top things to see and do in Siesta Isle?
San Carlos Bay - Bunche Beach Preserve is an attraction you might want to check out while you're in Siesta Isle. Key West Express and Bunche Beach are also worth a visit when you're out sightseeing in Fort Myers Beach.