Top Sanctuary Hotels

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Where to stay in Sanctuary

Find the best Sanctuary areas and neighborhoods for the activities you enjoy most.

A coastal scene with a lighthouse, beach, and ocean.

Mid Island

While visiting Mid Island, you might make a stop by sights like Sanibel Island Southern Beach and Periwinkle Way.

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West End

While visiting West End, you might make a stop by sights like Sanibel Island Southern Beach and J. N. Ding Darling National Wildlife Refuge.

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East End

While visiting East End, you might make a stop by sights like Sanibel Island Southern Beach and Sanibel Island Northern Beach.

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Beachview Country Club Estates

If you're spending some time in Beachview Country Club Estates, Periwinkle Way and Sanibel Island Golf Club are top sights worth seeing.

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Gulf Shores

While there might not be top attractions in Gulf Shores, you can explore the larger area and discover places like Bowman's Beach and J. N. Ding Darling National Wildlife Refuge.

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Top Sanctuary Hotel Reviews

The Bay Inn at Lani Kai

10/10 Excellent

"We stayed in the Bay Inn, which is the somewhat less expensive sister property to the Lani Kai beachfront resort. It’s directly across the street from the main hotel so really no big deal at all. No view, but that’s ok. Very good size room…full bedroom, seperate full living/eating/kitchenette area. Would be nice if they had a door separating the 2 spaces, but oh well. Nice large fridge/freezer, large microwave. Plenty of towels for bathroom and beach. Main hotel has loads of different food options, and bar options too, although on weeknights at least it was pretty empty. Beautiful beach, nice pool with lots of pool toys. Our room was ready early so we were able to check in very early. A couple of complaints… I know they want to make the price look cheaper but it’s really annoying when you get to the hotel and there is a fee for parking. I know lots of hotels do it but it’s still annoying. It’s $20 a day extra and there’s nothing you can do about it. There is nowhere else to park so why not just add it on to the price instead of being kind of sneaky about it. Also, you’re paying a lot of money to stay at this hotel, which is a beach hotel but if you want to go to the beach and have beach chairs and an umbrella you have to pay extra for that you can bring your own chair an umbrella if you want to set it up yourself, but I mean you’re going to a beach resort. I kind of feel like beach chairs, and an umbrella should just be offered to you for free."

Sanibel Inn

10/10 Excellent

"This survey only allows up to 5 stars. I would give it 10 if I could. This place is beautiful. The staff is amazing. The room upon arrival was spotless. Everything was in good working order. Stop searching for other properties. Book here, you will not regret it. Also, they do not nickel and dime you. Beach chairs, umbrella, kayaks, paddleboards,bicycles are all included. Food at the pool bar is very good. The ground are extraordinary."

Frequently asked questions

What is Sanctuary like?

Travelers are sure to enjoy a stay in Sanibel's Sanctuary neighborhood. Consider a visit to J. N. Ding Darling National Wildlife Refuge as part of your Sanctuary travel plans.

How many hotels are there in the Sanctuary area?

When you want to find places to stay in Sanibel, start by booking one of Expedia's 9 hotels and other accommodations in Sanctuary.

If I need to cancel my hotel reservation in Sanctuary, will I receive a refund?

Yes! You'll find that most room reservations are fully refundable as long as you cancel before the hotel's cancellation deadline, which often is within 24-48 hours of your check-in date. If your reservation is non-refundable, it might still be possible to cancel it and get a refund within a 24-hour period of booking. Enter your dates, click on "Search", then you can use the "fully refundable" filter to review top deals in Sanctuary.

Where can I learn more about changing or cancelling my trip to Sanctuary?

For more information about updating your trip to Sanctuary or cancelling it, click here.

What is there to do around this Sanibel neighborhood?

J. N. Ding Darling National Wildlife Refuge is an attraction you might want to check out while you're in Sanctuary. Castaways Marina and Blind Pass Beach are also worth a visit when you're out sightseeing in Sanibel.

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Our top choices for Sanctuary hotels

1. Holiday Inn Express Cape Coral-Fort Myers Area by IHG

2. Tween Waters Island Resort & Spa

3. Candlewood Suites Fort Myers Sanibel Gateway by IHG

4. La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway

5. Hilton Garden Inn Ft Myers

6. OYO Waterfront Hotel - Cape Coral/Fort Myers, FL

7. Fairfield Inn & Suites by Marriott Ft. Myers/Cape Coral

8. Homewood Suites by Hilton - Fort Myers

9. Hampton Inn & Suites Fort Myers Beach/Sanibel Gateway

10. Allure Suites

11. Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG

12. Residence Inn by Marriott Fort Myers Sanibel

13. Latitude 26 Waterfront Resort & Marina

14. Doubletree by Hilton Fort Myers at Bell Tower Shops

15. Lani Kai Beachfront Resort

16. Island Inn

17. Dolphin Key Resort

18. Sanibel Inn

19. Hampton Inn & Suites - Cape Coral/Fort Myers Area, FL

20. Marriott Sanibel Harbour Resort & Spa

Where to stay in Sanctuary

Mid Island

West End

East End

Beachview Country Club Estates

Gulf Shores

Top Sanctuary Hotel Reviews

The Bay Inn at Lani Kai

Frequently asked questions

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