What is Sanctuary like?

Travelers are sure to enjoy a stay in Sanibel's Sanctuary neighborhood. Consider a visit to J. N. Ding Darling National Wildlife Refuge as part of your Sanctuary travel plans.

How many hotels are there in the Sanctuary area?

When you want to find places to stay in Sanibel, start by booking one of Expedia's 8 hotels and other accommodations in Sanctuary.

If I need to cancel my hotel reservation in Sanctuary, will I receive a refund?

Yes! You'll find that most room reservations are fully refundable as long as you cancel before the hotel’s cancellation deadline, which often is within 24-48 hours of your check-in date. If your reservation is non-refundable, it might still be possible to cancel it and get a refund within a 24-hour period of booking. Enter your dates, click on "Search", then you can use the "fully refundable" filter to review top deals in Sanctuary.

Where can I learn more about changing or cancelling my trip to Sanctuary?

For more information about updating your trip to Sanctuary or cancelling it, click here .

What is there to do around this Sanibel neighborhood?

J. N. Ding Darling National Wildlife Refuge is an attraction you might want to check out while you're in Sanctuary. Castaways Marina and Blind Pass Beach are also worth a visit when you're out sightseeing in Sanibel.

Top Sanctuary Hotels

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Our top choices for Sanctuary hotels

1. Cape Coral Retreat w Pool & Court

24.2 km from Sanctuary

￥55,142 total

includes taxes & fees

Aug 15 - Aug 16

In-room safe, desk, laptop workspace, blackout drapes

2. Holiday Inn Express Cape Coral-Fort Myers Area by IHG

23.9 km from Sanctuary

Kara

￥17,726 total

includes taxes & fees

Aug 23 - Aug 24

3. Tween Waters Island Resort & Spa

3.7 km from Sanctuary

Sheryl

￥55,274 total

includes taxes & fees

Aug 14 - Aug 15

4. La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway

19.9 km from Sanctuary

ALICIA

￥12,777 total

includes taxes & fees

Aug 30 - Aug 31

5. Hilton Garden Inn Ft Myers

29.5 km from Sanctuary

carl

￥17,797 total

includes taxes & fees

Aug 12 - Aug 13

6. Residence Inn by Marriott Fort Myers Sanibel

19.3 km from Sanctuary

Louis

￥15,794 total

includes taxes & fees

Aug 30 - Aug 31

7. Fairfield Inn & Suites by Marriott Ft. Myers/Cape Coral

30.1 km from Sanctuary

Melissa

￥13,899 total

includes taxes & fees

Aug 14 - Aug 15

8. OYO Waterfront Hotel - Cape Coral/Fort Myers, FL

25.2 km from Sanctuary

Chrystal

￥9,411 total

includes taxes & fees

Aug 9 - Aug 10

9. Candlewood Suites Fort Myers Sanibel Gateway by IHG

25.4 km from Sanctuary

Amanda

￥9,254 total

includes taxes & fees

Aug 11 - Aug 12

10. Hampton Inn & Suites Fort Myers Beach/Sanibel Gateway

22.9 km from Sanctuary

Daveanand

￥14,447 total

includes taxes & fees

Aug 19 - Aug 20

11. Allure Suites

27.2 km from Sanctuary

Brian

￥13,543 total

includes taxes & fees

Aug 1 - Aug 2

12. Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG

23.1 km from Sanctuary

Lori

￥14,566 total

includes taxes & fees

Aug 30 - Aug 31

13. Doubletree by Hilton Fort Myers at Bell Tower Shops

30.8 km from Sanctuary

heather

￥17,949 total

includes taxes & fees

Aug 22 - Aug 23

14. Homewood Suites by Hilton - Fort Myers

30.9 km from Sanctuary

Fathi

￥18,242 total

includes taxes & fees

Aug 11 - Aug 12

Floating Coconut Cottage Houseboat | Terrace/patio

15. Latitude 26 Waterfront Resort & Marina

22 km from Sanctuary

Rick

￥16,588 total

includes taxes & fees

Aug 11 - Aug 12

16. Sundial Beach Resort & Spa

Mid Island, 12.8 km from Sanctuary

Carla

￥79,727 total

includes taxes & fees

Aug 14 - Aug 15

17. Dolphin Key Resort

23.8 km from Sanctuary

Jacquelyn

￥16,146 total

includes taxes & fees

Aug 30 - Aug 31

18. Sanibel Inn

East End, 13.8 km from Sanctuary

Lisa

￥59,248 total

includes taxes & fees

Aug 19 - Aug 20

Grand Studio Suite, Kitchenette | Desk, laptop workspace, WiFi (free), bed sheets

19. Lazy Cuckoo Inn

22.1 km from Sanctuary

Brooklyn

￥15,345 total

includes taxes & fees

Aug 6 - Aug 7

20. Hampton Inn & Suites - Cape Coral/Fort Myers Area, FL

22.6 km from Sanctuary

Beverley

￥16,488 total

includes taxes & fees

Aug 23 - Aug 24

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Where to stay in Sanctuary

Find the best Sanctuary areas and neighborhoods for the activities you enjoy most.

A coastal scene with a lighthouse, beach, and ocean.

Mid Island

While visiting Mid Island, you might make a stop by sights like Periwinkle Way and Sanibel Island Southern Beach.

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West End

While visiting West End, you might make a stop by sights like J. N. Ding Darling National Wildlife Refuge and Bowman's Beach.

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East End

While visiting East End, you might make a stop by sights like Sanibel Island Northern Beach and Sanibel Island Lighthouse.

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A cyclist on a paved path alongside a road with cars, palm trees, and a liquor store sign.

Beachview Country Club Estates

If you're spending some time in Beachview Country Club Estates, Periwinkle Way and Sanibel Island Golf Club are top sights worth seeing.

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Gulf Shores

While there might not be top attractions in Gulf Shores, you can explore the larger area and discover places like Bowman's Beach and J. N. Ding Darling National Wildlife Refuge.

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Top Sanctuary Hotel Reviews

Best Western Plus Beach Resort

10/10 Excellent

"Amazing in all aspects, great location"

DiamondHead Beach Resort

10/10 Excellent

"The room was spacious, comfortable, and clean with separate sitting area and kitchenette, 2 TVs and spacious balcony with lounge chairs and table with chairs. The view was great, parking was easy and beach chairs and umbrellas were available for all. Beach area is huge with white sand. I didn’t use the pool, but the area was very nice. There are two restaurants and bars onsite with live entertainment at times. My only complaint is that the room air conditioner was very noisy. There was also construction noise from neighboring property and street which made it unpleasant to use the balcony during the day, but that was beyond the control of DiamondHead, and understandable considering the island is still recovering from Hurricane Ian."

Sanibel Island Beach Resort

10/10 Excellent

"We had a wonderful stay Our room was spacious, well maintained and clean. The air-conditioning worked perfectly. It kept the room cool and comfortable throughout our stay. The staff from the time you checked in, to the restaurant, to the bar was friendly, attentive and provided excellent service. Definitely don’t miss out on having breakfast, lunch or dinner on site, the food was excellent. Would definitely stay here again and recommend to others."

Find hotels in Sanctuary, Sanibel

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Our top choices for Sanctuary hotels

1. Cape Coral Retreat w Pool & Court

2. Holiday Inn Express Cape Coral-Fort Myers Area by IHG

3. Tween Waters Island Resort & Spa

4. La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway

5. Hilton Garden Inn Ft Myers

6. Residence Inn by Marriott Fort Myers Sanibel

7. Fairfield Inn & Suites by Marriott Ft. Myers/Cape Coral

8. OYO Waterfront Hotel - Cape Coral/Fort Myers, FL

9. Candlewood Suites Fort Myers Sanibel Gateway by IHG

10. Hampton Inn & Suites Fort Myers Beach/Sanibel Gateway

11. Allure Suites

12. Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG

13. Doubletree by Hilton Fort Myers at Bell Tower Shops

14. Homewood Suites by Hilton - Fort Myers

15. Latitude 26 Waterfront Resort & Marina

16. Sundial Beach Resort & Spa

17. Dolphin Key Resort

18. Sanibel Inn

19. Lazy Cuckoo Inn

20. Hampton Inn & Suites - Cape Coral/Fort Myers Area, FL

Where to stay in Sanctuary

Mid Island

West End

East End

Beachview Country Club Estates

Gulf Shores

Top Sanctuary Hotel Reviews

Best Western Plus Beach Resort

Frequently asked questions

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