Sanctuary Vacations

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to ￥45,448 when you book a flight and hotel together*

  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

  • Rest easy

    Plan, book, and manage your trip all in one place

Where to stay in Sanctuary

Find the best Sanctuary areas and neighborhoods for the activities you enjoy most. Learn more about Sanctuary
Default Image

West End

3 out of top 10 points of interest in this area

While visiting West End, you might make a stop by sights like J. N. Ding Darling National Wildlife Refuge and Bowman's Beach.

Find hotels in West End

Sanctuary Hotel Deals

Lani Kai Beachfront Resort

Lani Kai Beachfront Resort

3.5 out of 5
1400 Estero Blvd Fort Myers Beach FL
Fully refundableReserve now, pay when you stay
The price is ￥29,162 per night from Jan 22 to Jan 23
￥29,162
￥36,043 total
Jan 22 - Jan 23
includes taxes & fees
9/10 Wonderful! (1,124 reviews)
This Resort doesn't pretend to be something it is not. If you're looking for luxury, you'll be a bit disappointed. But if you're looking for an "old school" beach front resort with everything you need for a great vacation, you cannot beat the Lani Kai. This family owned resort has been here since ...

Reviewed on Jan 17, 2026

Lani Kai Beachfront Resort
Sanibel Island Beach Resort

Sanibel Island Beach Resort

3 out of 5
1231 Middle Gulf Dr Sanibel FL
Fully refundableReserve now, pay when you stay
The price is ￥38,840 per night from Jan 21 to Jan 22
￥38,840
￥47,261 total
Jan 21 - Jan 22
includes taxes & fees
9/10 Wonderful! (1,538 reviews)
Clean room. Excestagf

Reviewed on Jan 16, 2026

Sanibel Island Beach Resort
Margaritaville Beach Resort Fort Myers

Margaritaville Beach Resort Fort Myers

4 out of 5
251 Crescent Street Fort Myers Beach FL
The price is ￥44,978 per night from Jan 21 to Jan 22
￥44,978
￥58,087 total
Jan 21 - Jan 22
includes taxes & fees
8.8/10 Excellent! (1,799 reviews)
Everything was wonderful! Our room was very nice so was the staff. The pool is amazing and so happy it’s heated. The pool games and dj was super fun! The pool servers and service super!

Reviewed on Jan 17, 2026

Margaritaville Beach Resort Fort Myers
See all 13,010 properties in Sanctuary
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Sanctuary vacation package cost?
Starting from as little as , you can tailor your Sanctuary package the way you want. Simply combine hotels, flights and car rentals and we'll reward you with discounts.
How do I get a cheap travel package to Sanctuary?
Booking a flight and hotel together with Expedia won't just save you time — it'll save you a pretty penny too. A Sanctuary vacation package makes it easy to organize your dream adventure. With more than 550 airlines across the world to choose from, finding convenient flights that suit your schedule won't be hard. On top of that, we've got over 1,000,000 properties globally to select from. Now that's what we call choice. No matter who you are, Expedia brings the world within your reach.
Where should I stay in Sanctuary?
A getaway to Sanctuary wouldn't be complete without seeing Bowmans Beach, Blind Pass Beach and Castaways Marina. Spend your evenings close to these top attractions and make sightseeing a breeze.
How far in advance should I book my Sanctuary vacation?
Reward yourself with the biggest variety at the lowest prices by booking your vacation to Sanctuary early. Airlines typically release flight tickets around 12 months prior to departure, so start your planning ASAP. That said, Expedia is committed to providing you with the best deals around, so it's never a bad time to book your dream vacation!
What does an Expedia Sanctuary travel package include?
That depends on what you're after. If you're traveling by yourself, you might decide to bundle flights and hotels. Taking the whole family to Sanctuary? A travel package that includes hotels, rental cars and flights might suit you better. Expedia gives you the freedom and flexibility to tailor-make your travel package.
What should I know before booking a Sanctuary travel package?
Booking all the parts of your escape together is a terrific way to save. Bundle your car rentals, airfares and hotels into one package. But you're not limited to hotels. Expedia offers all types of properties, including vacation rentals like beachfront villas and spacious residences. The list goes on!
Can I choose my airline with a Sanctuary Expedia vacation package?
Most definitely. Expedia has over 550 partner airlines to choose from globally. With so much choice, finding the perfect carrier to whisk you away to Sanctuary won't be difficult.
If I'm not able to travel, can I cancel my Sanctuary vacation package?
Don't stress if you're rethinking your Sanctuary vacation package — it's possible to change or amend your booking. And if you've booked it within the last 24 hours, you may be able to do it for free. However, bookings made more than 24 hours ago may incur fees from your hotel, airline or car rental company. We totally understand life can sometimes throw you a curveball, so make your way to our Customer Service Portal if that happens. When you're ready to make changes, we'll be here to help.

Discover the most popular places to visit in Sanctuary

Bowman\'s Beach which includes general coastal views and a sandy beach

Bowman's Beach

4.5/5(481 reviews)

Relax and revel in a visit to one of the area’s most beautiful beaches, great for swimming, fishing and finding special seashells.

Bowman's Beach

Things to do

Copacetic Day Sail

Copacetic Day Sail

￥10,960
per adult
100% of travellers recommend
Copacetic Day Sail
Dolphin Wildlife Cruise Fort Myers Beach

Dolphin Wildlife Cruise Fort Myers Beach

￥9,926
per adult
Dolphin Wildlife Cruise Fort Myers Beach
Fort Myers Beach Sunset and Dolphin Watching Cruise

Fort Myers Beach Sunset and Dolphin Watching Cruise

￥10,952
per adult
100% of travellers recommend
Fort Myers Beach Sunset and Dolphin Watching Cruise
See all activities in Sanibel
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.