Sanctuary Vacations

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to ￥109,000 when you book a flight and hotel together*

  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

  • Rest easy

    Plan, book, and manage your trip all in one place

Where to stay in Sanctuary

Find the best Sanctuary areas and neighborhoods for the activities you enjoy most. Learn more about Sanctuary
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Mid Island

2 out of top 10 points of interest in this area

While visiting Mid Island, you might make a stop by sights like Periwinkle Way and Sanibel Island Southern Beach.

Find hotels in Mid Island

Sanctuary Hotel Deals

Margaritaville Beach Resort Fort Myers

Margaritaville Beach Resort Fort Myers

4 out of 5
251 Crescent Street Fort Myers Beach FL
The price is ￥29,535 per night from May 26 to May 27
￥29,535
￥40,805 total
May 26 - May 27
includes taxes & fees
9/10 Wonderful! (2,071 reviews)
The place was very nice my wife and I love it

Reviewed on May 7, 2026

Margaritaville Beach Resort Fort Myers
Lani Kai Beachfront Resort

Lani Kai Beachfront Resort

3.5 out of 5
1400 Estero Blvd Fort Myers Beach FL
Fully refundableReserve now, pay when you stay
The price is ￥22,748 per night from May 12 to May 13
￥22,748
￥28,863 total
May 12 - May 13
includes taxes & fees
9/10 Wonderful! (1,462 reviews)
From the moment I stepped out of my Uber, I was immersed in a perfect haven for my solo trip. The staff were helpful and friendly. My room was clean and updated. The view from my balcony was spectacular. The sweet young ladies who waited on us at the beach were truly lovely. Viviana on the rooftop ...

Reviewed on May 8, 2026

Lani Kai Beachfront Resort
Sanibel Island Beach Resort

Sanibel Island Beach Resort

3 out of 5
1231 Middle Gulf Dr Sanibel FL
The price is ￥35,354 per night from May 31 to Jun 1
￥35,354
￥43,343 total
May 31 - Jun 1
includes taxes & fees
9.2/10 Wonderful! (1,869 reviews)
We loved it here. Room was nice and clean. It was beautiful and such a relaxing place. Nice beach chairs and umbrellas. Will definitely go back.

Reviewed on May 8, 2026

Sanibel Island Beach Resort
See all 13,159 properties in Sanctuary
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Sanctuary vacation package cost?
Starting from as little as , you can tailor your Sanctuary package the way you want. Simply combine hotels, flights and car rentals and we'll reward you with discounts.
How do I get a cheap travel package to Sanctuary?
Booking a flight and hotel together with Expedia won't just save you time — it'll save you a pretty penny too. A Sanctuary vacation package makes it easy to organize your dream adventure. With more than 550 airlines across the world to choose from, finding convenient flights that suit your schedule won't be hard. On top of that, we've got over 1,000,000 properties globally to select from. Now that's what we call choice. No matter who you are, Expedia brings the world within your reach.
Where should I stay in Sanctuary?
A getaway to Sanctuary wouldn't be complete without seeing Bowmans Beach, Blind Pass Beach and Castaways Marina. Spend your evenings close to these top attractions and make sightseeing a breeze.
How far in advance should I book my Sanctuary vacation?
Reward yourself with the biggest variety at the lowest prices by booking your vacation to Sanctuary early. Airlines typically release flight tickets around 12 months prior to departure, so start your planning ASAP. That said, Expedia is committed to providing you with the best deals around, so it's never a bad time to book your dream vacation!
What does an Expedia Sanctuary travel package include?
That depends on what you're after. If you're traveling by yourself, you might decide to bundle flights and hotels. Taking the whole family to Sanctuary? A travel package that includes hotels, rental cars and flights might suit you better. Expedia gives you the freedom and flexibility to tailor-make your travel package.
What should I know before booking a Sanctuary travel package?
Booking all the parts of your escape together is a terrific way to save. Bundle your car rentals, airfares and hotels into one package. But you're not limited to hotels. Expedia offers all types of properties, including vacation rentals like beachfront villas and spacious residences. The list goes on!
Can I choose my airline with a Sanctuary Expedia vacation package?
Most definitely. Expedia has over 550 partner airlines to choose from globally. With so much choice, finding the perfect carrier to whisk you away to Sanctuary won't be difficult.
If I'm not able to travel, can I cancel my Sanctuary vacation package?
Don't stress if you're rethinking your Sanctuary vacation package — it's possible to change or amend your booking. And if you've booked it within the last 24 hours, you may be able to do it for free. However, bookings made more than 24 hours ago may incur fees from your hotel, airline or car rental company. We totally understand life can sometimes throw you a curveball, so make your way to our Customer Service Portal if that happens. When you're ready to make changes, we'll be here to help.

Discover the most popular places to visit in Sanctuary

Bowman's Beach

Bowman's Beach

4.5/5(488 reviews)

Relax and revel in a visit to one of the area’s most beautiful beaches, great for swimming, fishing and finding special seashells.

Bowman's Beach

Things to do

Copacetic Day Sail

Copacetic Day Sail

￥11,119
per adult
100% of travellers recommend
Copacetic Day Sail
Southwest Florida Sunset Sail

Southwest Florida Sunset Sail

￥11,156
per adult
100% of travellers recommend
Southwest Florida Sunset Sail
Dolphin Wildlife Cruise Fort Myers Beach

Dolphin Wildlife Cruise Fort Myers Beach

￥10,184
per adult
100% of travellers recommend
Dolphin Wildlife Cruise Fort Myers Beach
See all activities in Sanibel
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.