Find hotels in Santa Cruz from ￥4,317

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
Jun 5 - Jun 7
Next weekend
Jun 12 - Jun 14

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Santa Cruz hotels

Outdoor pool

1. Sun Hotel

Sun Hotel
3.5 star property
Santa Cruz
8.2 out of 10, Very Good, (378 reviews)
"Very well located three start hotel. Clean with everything you need for an in/out night. Hotel needs a redoing."
United States
jose
The price is ￥17,269
￥17,269 total
Jun 9 - Jun 10
Sun Hotel
Outdoor pool, sun loungers

2. Hotel Cortez

Hotel Cortez
3.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (139 reviews)
"Beautiful hotel with very friendly and polite staff. The breakfast is delicious. I spent almost two weeks and I absolutely adored this place. The pool area is wonderful. I enjoyed the gym and the hydro massage area (jacuzzis). This is included with your room reservation, you just need to make a reservation ahead of time. I noticed that they cleaned and sanitized each one after it was used. Overall it’s an amazing and very clean place to stay."
United States
Yefiny
The price is ￥17,126
￥17,126 total
Jun 19 - Jun 20
Hotel Cortez
Honeymoon Room, 1 King Bed | Egyptian cotton sheets, premium bedding, pillowtop beds, minibar

3. HOTEL OSHO

HOTEL OSHO
3.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (50 reviews)
"Room was great and staff were very accommodating!"
Canada
David
The price is ￥7,452
￥9,851 total
Jun 7 - Jun 8
HOTEL OSHO
Seasonal outdoor pool

4. Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
3.5 star property
Santa Cruz
9.0 out of 10, Wonderful, (380 reviews)
"Nice hotel"
United States
Mabel Marisel
The price is ￥20,251
￥20,251 total
Jun 27 - Jun 28
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
Premium Room, 1 Queen Bed, Bathtub | Minibar, in-room safe, individually decorated, individually furnished

5. Cosmopolitano Hotel Boutique

Cosmopolitano Hotel Boutique
3.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (132 reviews)
"Everything was excellent! Clean room, delicious food, friendly staff, great location!"
United States
Heidi
The price is ￥11,791
￥11,791 total
Jun 8 - Jun 9
Cosmopolitano Hotel Boutique
Double Room, 1 Queen Bed | Premium bedding, down comforters, minibar, blackout drapes

6. Hotel G

Hotel G
3.5 star property
Santa Cruz
7.8 out of 10, Good, (107 reviews)
"Excelente Hotel "
Mexico
JACOB
The price is ￥5,735
￥5,735 total
Jul 3 - Jul 4
Hotel G
Lounge

7. Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

Hampton by Hilton Santa Cruz/Equipetrol, Bolivia
4.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (276 reviews)
"The hotel truly exceeded all my expectations. The quality of the facilities, the service, and the excellent breakfast were outstanding."
United States
imilse de
The price is ￥16,182
￥16,182 total
Jun 6 - Jun 7
Hampton by Hilton Santa Cruz/Equipetrol, Bolivia
Outdoor pool, open 9:00 AM to 8:00 PM, sun loungers

8. Premium Suites Deluxe Aparthotel Equipetrol

Premium Suites Deluxe Aparthotel Equipetrol
3.5 star property
Santa Cruz
9.0 out of 10, Wonderful, (101 reviews)
"Great Location"
United States
Blanca
The price is ￥6,693
￥6,693 total
Jun 15 - Jun 16
Premium Suites Deluxe Aparthotel Equipetrol
Reception

9. Camino Real Hotel

Camino Real Hotel
4.5 star property
Santa Cruz
9.0 out of 10, Wonderful, (428 reviews)
"Definitely I would’ve recommend anybody who is looking for hotel because the service was excellent make me feel special since I walked in into the place and also I was impressed how clean the place was…Thanks for the service guys…Keep up this way..thanks again for everything…I’ll see you soon.🙏"
United States
Edwin
The price is ￥25,214
￥25,214 total
Jun 10 - Jun 11
Camino Real Hotel
Outdoor pool, pool umbrellas, sun loungers

10. Marriott Santa Cruz de la Sierra Hotel

Marriott Santa Cruz de la Sierra Hotel
5.0 star property
Santa Cruz
9.0 out of 10, Wonderful, (233 reviews)
"Amazing hotel"
United States
Deivis
The price is ￥17,701
￥17,701 total
Jun 20 - Jun 21
Marriott Santa Cruz de la Sierra Hotel
Living area

11. Posada Express Fast Check

Posada Express Fast Check
3.0 star property
Santa Cruz
7.8 out of 10, Good, (7 reviews)
"The posada expres was closed and "
United States
Marcelo
The price is ￥6,763
￥7,483 total
Jun 6 - Jun 7
Posada Express Fast Check
Restaurant

12. Ibis Santa Cruz DE LA Sierra

Ibis Santa Cruz DE LA Sierra
3.0 star property
Santa Cruz
9.4 out of 10, Exceptional, (118 reviews)
"Nice place"
United States
Juan Carlos
The price is ￥9,498
￥9,498 total
Jun 5 - Jun 6
Ibis Santa Cruz DE LA Sierra
Comfort Twin Room | Bathroom

13. Surbackpackers

Surbackpackers
3.0 star property
Santa Cruz
The price is ￥3,358
￥3,358 total
Jun 7 - Jun 8
Surbackpackers
Front of property

14. Chairú Eco Hotel

Chairú Eco Hotel
3.5 star property
Santa Cruz
9.6 out of 10, Exceptional, (67 reviews)
"Clean room and friendly staff "
United States
marcia
The price is ￥8,635
￥8,635 total
Jun 5 - Jun 6
Chairú Eco Hotel
Lobby sitting area

15. Novotel Santa Cruz De La Sierra

Novotel Santa Cruz De La Sierra
5.0 star property
Santa Cruz
9.0 out of 10, Wonderful, (116 reviews)
"REALLY NICE HOTEL. STAFF WONDERFULL"
United States
ERNESTO
The price is ￥16,790
￥16,790 total
Jun 23 - Jun 24
Novotel Santa Cruz De La Sierra
Reception

16. Lido Hotel

Lido Hotel
3.0 star property
Santa Cruz
9.0 out of 10, Wonderful, (41 reviews)
"Lovely stay for a night. Great location within easy walking distance to the center."
United States
Gabrielle
The price is ￥5,611
￥5,611 total
Jun 15 - Jun 16
Lido Hotel
Standard Suite, 1 Queen Bed | Hypo-allergenic bedding, down comforters, desk, laptop workspace

17. Equipetrol Suites Apart Hotel

Equipetrol Suites Apart Hotel
2.5 star property
Santa Cruz
8.8 out of 10, Excellent, (13 reviews)
"Perfect hotel"
Turkey
Yener
The price is ￥7,231
￥7,231 total
Jun 6 - Jun 7
Equipetrol Suites Apart Hotel
Restaurant

18. Prince Hotel

Prince Hotel
3.0 star property
Santa Cruz
8.8 out of 10, Excellent, (6 reviews)
"Nice place "
United States
Marco
The price is ￥6,908
￥7,228 total
Jun 5 - Jun 6
Prince Hotel
Terrace/patio

19. Hotel Las Américas

Hotel Las Américas
3.0 star property
Santa Cruz
7.8 out of 10, Good, (12 reviews)
"Very clean room and great staff"
Canada
Stanley
The price is ￥4,474
￥4,474 total
Jun 6 - Jun 7
Hotel Las Américas
View from property

20. Hotel Continental Park

Hotel Continental Park
3.0 star property
Santa Cruz
8.6 out of 10, Excellent, (26 reviews)
"This is a great option for accomodations near the center of the city. Perhaps 5 or 6 block walk to the main square. Lots of options for restaurantes. The garage is easily accesible. The pool was great and we took advantage of the sauna. Breakfast was great as well. Good variety of food. Staff at the desk was polite and helpful. "
Canada
Gregory
The price is ￥10,189
￥10,189 total
Jun 5 - Jun 6
Hotel Continental Park
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Vacation Rentals in Santa Cruz

Aparthotel
Outdoor pool, open 9:00 AM to 8:00 PM, sun loungers
Premium Suites Deluxe Aparthotel Equipetrol

Premium Suites Deluxe Aparthotel Equipetrol

Premium Suites Deluxe Aparthotel Equipetrol
3.5 star property
Santa Cruz
9.0 out of 10, Wonderful, (101 reviews)
"Great Location"
Premium Suites Deluxe Aparthotel Equipetrol
See all vacation rentals
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Where to stay in Santa Cruz

Find the best Santa Cruz areas and neighborhoods for the activities you enjoy most. Learn more about Santa Cruz
Learn more about Santa Cruz

Hamacas

While Hamacas isn't home to many top sights, Santa Cruz Zoo and Las Brisas Shopping Center are some notable places to visit nearby.

Stay near popular Santa Cruz attractions

Plaza 24 de Septiembre

4.4/5 (164 reviews)
Plaza 24 de Septiembre buzzes with local culture beneath swaying palms and colonial architecture. Climb the Cathedral's bell tower for spectacular city views while sampling authentic Bolivian coffee from vendors.
See properties

Learn more about Santa Cruz

Tropical energy pulses through Plaza 24 de Septiembre, where locals gather under palm trees and the Metropolitan Cathedral's twin towers stand watch. Biocentro Güembé offers rainforest trails with butterfly gardens, while the massive Ventura Mall provides air-conditioned shopping when afternoon temperatures climb.

See all hotels in Santa Cruz

Top Santa Cruz Hotel Reviews

Apart Hotel Premium Suites Santa Cruz

Apart Hotel Premium Suites Santa Cruz

10/10 Excellent
"Great location."
Ruben 2-night trip
Posted 4 hours ago
Apart Hotel Premium Suites Santa Cruz

More cheap stays in Santa Cruz

Equipetrol Suites Apart Hotel

Equipetrol Suites Apart Hotel

Equipetrol Santa Cruz Departamento de Santa Cruz
The price is ￥7,231 per night from Jun 6 to Jun 7
￥7,231
￥7,231 total
Jun 6 - Jun 7

Frequently asked questions

What's the best place for a stay in Santa Cruz?
Ibis Santa Cruz DE LA Sierra is one of the top choices for your stay based on our traveler data. This hotel offers a restaurant and free parking. Other good choices for your visit include Sun Hotel and Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel. See all available top hotels, or vacation rentals in Santa Cruz.
What's the top vacation rental that Santa Cruz has to offer?
Casa Vida: Visitors give good reviews to this Santa Cruz vacation home rental, which is located in a rural location and has an outdoor pool, a patio, and a barbecue grill to put you at ease in your new surroundings. It has 3 bedrooms as well as a kitchen with a full-sized fridge, a stovetop, and a microwave, so you can cook with friends or family. Kick off your shoes and enjoy yourself with a private yard and a selection of games. Some other homes for rent in Santa Cruz include Seasonal House and Jose Luis Noya. See all vacation rentals in Santa Cruz.
If I need to cancel my hotel reservation in Santa Cruz, will I receive a refund?
Yes! Most hotel reservations are fully refundable as long as you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If your reservation is non-refundable, you might still have the option to cancel and get a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Santa Cruz.
Where can I learn more about changing or cancelling my trip to Santa Cruz?
To find more details about picking new dates or cancelling your trip to Santa Cruz, head over to our customer service page.
What's the best budget-friendly accommodation in Santa Cruz?
Based on our traveler reviews, residencial francia - Hostel is a top choice for a less expensive stay. Other choices for your budget-friendly stay include Travelero Hostel ans Tours and Residencial Ikandire II. View all budget hotels in Santa Cruz.
What's the best accommodation for a family trip to Santa Cruz?
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel is a hotel with 2 restaurants and free parking, and it's a top choice on Expedia for families. Other choices for your stay with the kids include Marriott Santa Cruz de la Sierra Hotel and Novotel Santa Cruz De La Sierra. Attractions like Santa Cruz Zoo and Play Land Amusement Park are also fun for kids of all ages. Find more child-friendly accommodations in Santa Cruz.
What is the top LGBTQ-friendly accommodation in Santa Cruz?
Hampton by Hilton Santa Cruz/Equipetrol, Bolivia is a top LGBTQ-friendly hotel that features free breakfast and free WiFi. Swissôtel Santa Cruz De La Sierra and Radisson Hotel Santa Cruz are other good choices for your trip. See all available hotels listed as LGBTQ-friendly in Santa Cruz.
What's the best pet-friendly hotel in Santa Cruz?
Casa Por Temporadas is a top dog-friendly guesthouse, and offers an outdoor pool along with in-room kitchens for its human guests. Other good options for you and your pet's trip include Ibis Santa Cruz DE LA Sierra and Hotel LP Equipetrol. See more pet-friendly hotel accommodations in Santa Cruz.
Where is the best place to stay close to Plaza 24 de Septiembre?
Adjacent to Plaza 24 de Septiembre, Nomad Hostel is one of the top choices for your stay based on our traveler data, and this property offers a restaurant and a bar. Other good options close by include Senses Centro and Cosmopolitano Hotel Boutique.
What about the best place to stay near Ventura Mall?
One of the top choices for your stay is Camino Real Hotel, located next to Ventura Mall, and this 4-star hotel offers 2 bars and a restaurant. Los Tajibos Hotel And Convention Center and Marriott Santa Cruz de la Sierra Hotel are two other good choices in the immediate area.
What's the best luxury accommodation in Santa Cruz?
Marriott Santa Cruz de la Sierra Hotel is a luxury hotel with a full-service spa and a rooftop terrace, and it's a popular choice for Expedia travelers looking for an elegant place to stay. Novotel Santa Cruz De La Sierra and Camino Real Hotel are other upscale choices for your vacation. Find more luxury hotels in Santa Cruz.
What are some accommodations with pools in Santa Cruz?
Yotau All Suites Hotel is a top hotel with 2 outdoor pools, a children's pool, and 2 restaurants. A couple of other options that offer an onsite pool include Buganvillas Hotel Suites & Spa and Royal Lodge Hotel. View all hotels with pools in Santa Cruz.
What is the best spa hotel in Santa Cruz?
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel is a top spa hotel featuring a fitness center, a hair salon, and a bar. Enjoy a facial, body scrub, or hydrotherapy at Los Tajibos Club Spa. Other popular spa hotels in Santa Cruz include Marriott Santa Cruz de la Sierra Hotel and Camino Real Hotel. See all spa hotels in Santa Cruz.
What's the best hotel for staying near Viru Viru International Airport (VVI)?
Sun Hotel is a popular 3.5-star hotel featuring free breakfast and a restaurant. It's located a short 1.3 mi (2.1 km) from Viru Viru Intl. Airport.
How is it to stay in Santa Cruz?
Visitors to Santa Cruz are sure to enjoy the shopping. Tourists can also enjoy the city's cafes, zoo, and cathedral. In Santa Cruz, there are 289 hotels and other accommodations to choose from. Find out more about Santa Cruz.
What should I do while I'm visiting Santa Cruz?
Cultural venues include Sacred Art Museum, Ethno-folkloric Museum, and Cine Center. Landmarks like San Lorenzo Cathedral, Plaza 24 de Septiembre, and Blacutt Square might be worth a visit. Natural beauty is on display at Arenal Park, Guembe Biocenter, and Lomas de Arena Regional Park. Check out what more to see and do in Expedia's Santa Cruz guide.
How should I get around Santa Cruz?
To see more of the larger area, ride aboard one of the trains from Santa Cruz de la Sierra Station. If you want to venture out around the area, you may want a rental car in Santa Cruz for your journey.
What's the weather like in Santa Cruz?
The hottest months are usually October and November with an average temp of 79°F, while the coldest months are June and July with an average of 70°F. Average annual precipitation for Santa Cruz is 48 inches.