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Our top choices for Otay Mesa West hotels

Wyndham San Diego Bayside

Wyndham San Diego Bayside
4.0 star property
19.2 km from Otay Mesa West
8.4 out of 10, Very Good, (6015)
"Always an amazing stay"
United States
Jana
The price is ¥19,806
¥28,406 total
includes taxes & fees
Jan 4 - Jan 5
Wyndham San Diego Bayside

Hyatt Regency Mission Bay Spa and Marina

Hyatt Regency Mission Bay Spa and Marina
4.0 star property
Mission Bay, 27.2 km from Otay Mesa West
8.4 out of 10, Very Good, (1589)
"Totally Recommend! Rooms are really clean and comfortable, the staff are great as well. "
United States
Fernando
The price is ¥20,955
¥32,361 total
includes taxes & fees
Jan 10 - Jan 11
Hyatt Regency Mission Bay Spa and Marina

Wyndham Garden San Diego Near SeaWorld

Wyndham Garden San Diego Near SeaWorld
3.0 star property
24.8 km from Otay Mesa West
7.4 out of 10, Good, (4129)
"Get location to the airport, safe, great staff, & overall wonderful stay"
United States
Tyler
The price is ¥13,222
¥15,198 total
includes taxes & fees
Jan 6 - Jan 7
Wyndham Garden San Diego Near SeaWorld

DoubleTree by Hilton Hotel San Diego - Mission Valley

DoubleTree by Hilton Hotel San Diego - Mission Valley
4.0 star property
23.5 km from Otay Mesa West
8.4 out of 10, Very Good, (1446)
"The room was super quiet and clean. The staff was kind at check in and check out. We would definitely stay here again. "
United States
Janelle
The price is ¥18,465
¥21,224 total
includes taxes & fees
Jan 4 - Jan 5
DoubleTree by Hilton Hotel San Diego - Mission Valley

Manchester Grand Hyatt San Diego

Manchester Grand Hyatt San Diego
4.0 star property
Marina District, 18.2 km from Otay Mesa West
9.0 out of 10, Wonderful, (2882)
"Lovely hotel with friendly staff."
United States
Lynnea
The price is ¥27,523
¥40,432 total
includes taxes & fees
Jan 2 - Jan 3
Manchester Grand Hyatt San Diego

Sheraton San Diego Resort

Sheraton San Diego Resort
4.0 star property
21.4 km from Otay Mesa West
8.4 out of 10, Very Good, (3181)
"The stay and staff were wonderful and very helpful.."
United States
Elsie
The price is ¥19,548
¥28,100 total
includes taxes & fees
Jan 2 - Jan 3
Sheraton San Diego Resort

The DEXTRO Little Italy, BW Premier Collection

The DEXTRO Little Italy, BW Premier Collection
3.0 star property
19.1 km from Otay Mesa West
8.8 out of 10, Excellent, (834)
"would stay again and recommend "
United States
Brendi
The price is ¥17,280
¥20,035 total
includes taxes & fees
Jan 4 - Jan 5
The DEXTRO Little Italy, BW Premier Collection

San Diego Mission Bay Resort

San Diego Mission Bay Resort
4.0 star property
Mission Bay, 26.7 km from Otay Mesa West
8.4 out of 10, Very Good, (1317)
"Room was super clean and updated, location up against the bay was perfect. We really enjoyed our stay and want to come back soon!"
United States
Haley
The price is ¥21,455
¥32,930 total
includes taxes & fees
Jan 4 - Jan 5
San Diego Mission Bay Resort

Hilton San Diego Bayfront

Hilton San Diego Bayfront
4.0 star property
Marina District, 17.2 km from Otay Mesa West
8.6 out of 10, Excellent, (1893)
"Great options for breakfast Beautiful property"
United States
Melissa
The price is ¥18,673
¥29,317 total
includes taxes & fees
Jan 4 - Jan 5
Hilton San Diego Bayfront

Hampton Inn San Diego-Downtown

Hampton Inn San Diego-Downtown
2.5 star property
19.3 km from Otay Mesa West
8.2 out of 10, Very Good, (2319)
"Nice and convenient place to stay!"
United States
Esperanza
The price is ¥16,220
¥18,806 total
includes taxes & fees
Jan 18 - Jan 19
Hampton Inn San Diego-Downtown

Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter

Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter
3.0 star property
Gaslamp Quarter, 17.6 km from Otay Mesa West
9.0 out of 10, Wonderful, (1241)
"Clean, courteous staff, good location. "
United States
Carla
The price is ¥22,875
¥26,523 total
includes taxes & fees
Jan 3 - Jan 4
Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter

Bay Club Hotel & Marina

Bay Club Hotel & Marina
3.5 star property
22.1 km from Otay Mesa West
9.2 out of 10, Wonderful, (3237)
"Great stay and location!"
United States
Jason
The price is ¥16,748
¥19,251 total
includes taxes & fees
Jan 4 - Jan 5
Bay Club Hotel & Marina

Sycuan Casino Resort

Sycuan Casino Resort
4.0 star property
31.4 km from Otay Mesa West
9.2 out of 10, Wonderful, (1651)
"Very nice getaway for the family "
United States
Richard
Sycuan Casino Resort

Staypineapple, Hotel Z, Gaslamp San Diego

Staypineapple, Hotel Z, Gaslamp San Diego
3.0 star property
Gaslamp Quarter, 17.8 km from Otay Mesa West
9.4 out of 10, Exceptional, (1001)
"Great location "
United States
Mohammad
The price is ¥13,625
¥20,316 total
includes taxes & fees
Jan 6 - Jan 7
Staypineapple, Hotel Z, Gaslamp San Diego

The Bristol Hotel San Diego

The Bristol Hotel San Diego
3.5 star property
18.5 km from Otay Mesa West
8.6 out of 10, Excellent, (1469)
"I loved my stay here"
United States
José
The price is ¥22,167
¥25,702 total
includes taxes & fees
Jan 2 - Jan 3
The Bristol Hotel San Diego

Marriott Marquis San Diego Marina

Marriott Marquis San Diego Marina
4.0 star property
Marina District, 17.9 km from Otay Mesa West
9.2 out of 10, Wonderful, (1964)
"Great place to stay, everything close by"
United States
Manjinder
The price is ¥28,618
¥41,398 total
includes taxes & fees
Jan 9 - Jan 10
Marriott Marquis San Diego Marina

Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG

Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG
2.5 star property
11 km from Otay Mesa West
8.0 out of 10, Very Good, (1569)
"Great place to stay. Really clean and helpful staff "
United States
Zulma
The price is ¥18,609
¥21,168 total
includes taxes & fees
Jan 11 - Jan 12
Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG

Comfort Inn San Diego Old Town

Comfort Inn San Diego Old Town
2.5 star property
Old Town San Diego, 23.2 km from Otay Mesa West
8.2 out of 10, Very Good, (1920)
"Great stay "
United States
Vanessa
The price is ¥14,261
¥16,393 total
includes taxes & fees
Jan 13 - Jan 14
Comfort Inn San Diego Old Town

The Dana on Mission Bay

The Dana on Mission Bay
3.5 star property
Mission Bay, 27.1 km from Otay Mesa West
9.0 out of 10, Wonderful, (3952)
"Great spot, great hotel, great food options!"
United States
Demes SP
The price is ¥21,737
¥28,114 total
includes taxes & fees
Jan 4 - Jan 5
The Dana on Mission Bay

Hampton Inn San Diego/Mission Valley

Hampton Inn San Diego/Mission Valley
2.5 star property
23.5 km from Otay Mesa West
8.6 out of 10, Excellent, (1341)
"Clean room, Good breakfast and close to all attractions"
United States
SRIVANI
The price is ¥14,418
¥16,573 total
includes taxes & fees
Jan 25 - Jan 26
Hampton Inn San Diego/Mission Valley
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Otay Mesa West

Find the best Otay Mesa West areas and neighborhoods for the activities you enjoy most.

Downtown San Diego

Cultural and financial hub, Downtown San Diego boasts the Symphony, Opera, theaters, museums, and historic sites like Gaslamp Quarter. Enjoy diverse shops, dining, nightlife, and convenient public transport options.

Gaslamp Quarter

Downtown San Diego's historic district boasts Victorian-era buildings, now housing vibrant restaurants, shops, and entertainment venues. Stroll from Broadway to Harbor Drive, and 4th to 6th Avenue, admiring the newly installed gaslamps at Market Street.

Pacific Beach

Boasting a lively nightlife scene, Pacific Beach offers miles of sandy shores, a bustling 3.2-mile boardwalk, and attractions like Crystal Pier and Kate Sessions Park. Enjoy local shops, bars, and eateries along the vibrant walkway.

Mission Beach

Spanning nearly two miles of oceanfront, this sandbar community offers sunbathing, surfing, and beach volleyball, with nearby attractions like Belmont Park's Giant Dipper Roller Coaster and SeaWorld in Mission Bay Park.

Ocean Beach

Ocean Beach is known for its stunning beaches, and with sights like Dog Beach and Sunset Cliffs Natural Park, you won't get bored spending a day wandering around this part of San Diego.

Top Otay Mesa West Hotel Reviews

Frequently asked questions

What is Otay Mesa West like?
Otay Mesa West is a neighborhood that travelers like for its cathedral.
If I need to cancel my hotel reservation in Otay Mesa West, will I receive a refund?
Yes, you'll find most room reservations are fully refundable provided that you cancel prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of your check-in date. If you booked a non-refundable reservation, it may still be possible to cancel it and be given a refund within 24 hours of your booking. Add your dates and click on "Search", then you can filter by "fully refundable" to review the top deals on offer in Otay Mesa West.
Where can I learn more about changing or cancelling my trip to Otay Mesa West?
To find more details about rescheduling or cancelling your trip to Otay Mesa West, click here.
What is there to do around this San Diego neighborhood?
A few places to visit in the area around Otay Mesa West include San Ysidro Border Crossing, Las Americas Premium Outlets, and Sesame Place San Diego. While you're out sightseeing in San Diego, be sure to visit other sights like Tijuana Customs - Garita El Chaparral or North Island Credit Union Amphitheatre.
How can I get around Otay Mesa West and the greater San Diego area?
Ready to get out and explore the city? Iris Avenue Trolley Station is the closest metro station.

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