Otay Mesa West Vacations from ¥227,051

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The Latest Otay Mesa West Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Paradise Point Resort & Spa
Beach Village at The Del, LXR Hotels & Resorts
Shore House at The Del, LXR Hotels & Resorts
La Jolla Shores Hotel
Kona Kai San Diego

Where to stay in Otay Mesa West

Find the best Otay Mesa West areas and neighborhoods for the activities you enjoy most. Learn more about Otay Mesa West

Otay Mesa West Hotel Deals

Hard Rock Hotel San Diego

Hard Rock Hotel San Diego

4 out of 5
207 5th Ave San Diego CA
Fully refundableReserve now, pay when you stay
The price is ¥27,169 per night from Jan 22 to Jan 23
¥27,169
¥39,139 total
Jan 22 - Jan 23
includes taxes & fees
8.8/10 Excellent! (3,251 reviews)
Clean room

Reviewed on Jan 20, 2026

Hard Rock Hotel San Diego
Sheraton San Diego Resort

Sheraton San Diego Resort

4 out of 5
1380 Harbor Island Dr San Diego CA
Fully refundableReserve now, pay when you stay
The price is ¥31,480 per night from Jan 22 to Jan 23
¥31,480
¥43,145 total
Jan 22 - Jan 23
includes taxes & fees
8.2/10 Very Good! (3,255 reviews)
I stayed in one of the newly-remodeled rooms overlooking the pool/bay in the Marina Tower. Really lovely and the room was exceptionally well-appointed. Great view! The staff was also accomodating with arranging a day-rate for use of the room since I wasn't flying out until the evening. Would absolutely ...

Reviewed on Jan 19, 2026

Sheraton San Diego Resort
Courtyard by Marriott San Diego Downtown Little Italy

Courtyard by Marriott San Diego Downtown Little Italy

4 out of 5
1646 Front St San Diego CA
Fully refundableReserve now, pay when you stay
The price is ¥25,469 per night from Feb 15 to Feb 16
¥25,469
¥29,531 total
Feb 15 - Feb 16
includes taxes & fees
8.8/10 Excellent! (270 reviews)
Nice room. Great location

Reviewed on Jan 20, 2026

Courtyard by Marriott San Diego Downtown Little Italy
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does an Otay Mesa West vacation package cost?
Discover the best of Otay Mesa West from as little as ¥227,051. Choose from a wonderful selection of flights, hotels and rental cars to suit every style and budget. You can score even better deals when you add some experiences or tours to your package.
How do I get a cheap travel package to Otay Mesa West?
Booking an Otay Mesa West vacation package with Expedia is the easiest way to save. We have over 550 partner airlines and 1,000,000 properties across the globe. With such an awesome range to select from, you'll have no trouble putting together your next dream vacation.
Where should I stay in Otay Mesa West?
You'll want to stay where the action is. Many people book hotels around popular attractions, like Las Americas Premium Outlets, North Island Credit Union Amphitheatre and Aquatica.
How far in advance should I book my Otay Mesa West vacation?
Smart travelers will likely want to book early. You can normally start comparing international fares on Expedia up to a year before your intended flight. If you're booking last minute, don't despair. Low prices sometimes appear just weeks before departure dates.
What does an Expedia Otay Mesa West travel package include?
It all depends on what type of getaway you're contemplating. Otay Mesa West vacation deals can include hotels, car rentals and flights. You can mix and match to find the travel package that fits your needs. You can also add on experiences and activities after you've booked to score even bigger discounts.
What should I know before booking an Otay Mesa West travel package?
Get ready to save with an Expedia travel package. Bundle your airfares, rental cars and hotels and pick up fabulous discounts. You're not limited to hotels, though. Book with us and select from beach villas, mountain cabins and everything in between!
Can I choose my airline with an Otay Mesa West Expedia vacation package?
With a vacation package, you're the boss. Whether you'd like to fly to Otay Mesa West in economy or business class, simply pick from the available airline options. Expedia has access to over 550 partner airlines all over the world.
If I'm not able to travel, can I cancel my Otay Mesa West vacation package?
You can. We get that even the best-laid plans can go awry, so we're here to help if you need to make changes to your Otay Mesa West vacation package. You may be able to cancel or change your itinerary for free if you've booked within 24 hours. Your hotel, airline or car rental company may impose a fee if you booked more than 24 hours ago. Head to our Customer Service Portal for further information. Also, be sure to check your itinerary for the nitty-gritty on change fees.

Discover the most popular places to visit in Otay Mesa West

Things to do

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.