Find all hotels by Hyatt Hotels in Otay Mesa, CA

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Compare rooms and suites by Hyatt Hotels in Otay Mesa with rates, reviews, and availability. Most hotels are fully refundable.

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Top Otay Mesa Hotel Reviews

Bay Club Hotel & Marina

Bay Club Hotel & Marina

10/10 Excellent
"Great location, clean rooms, helpful staff and good restaurant"
Clark 2-night trip
Posted 22 hours ago
Bay Club Hotel & Marina