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Check prices for these dates

This weekend
May 22 - May 24
Next weekend
May 29 - May 31

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Our top choices for O Brien hotels

Premium bedding, desk, blackout drapes, soundproofing

Palms Garden Inn

Palms Garden Inn
2.0 star property
Lake City
7.4 out of 10, Good, (608 reviews)
"Staff nice and helpful"
United States
Drew
The price is ￥10,316
￥11,606 total
includes taxes & fees
May 21 - May 22
Palms Garden Inn
Individually decorated, desk, laptop workspace, iron/ironing board

Days Inn by Wyndham Lake City I-10

Days Inn by Wyndham Lake City I-10
2.0 star property
Lake City
7.0 out of 10, Good, (1,003 reviews)
"Low cost but worth it"
United States
Michael
The price is ￥9,417
￥10,594 total
includes taxes & fees
May 24 - May 25
Days Inn by Wyndham Lake City I-10
Down comforters, pillowtop beds, blackout drapes, free WiFi

Super 8 by Wyndham Lake City

Super 8 by Wyndham Lake City
2.0 star property
Lake City
7.4 out of 10, Good, (714 reviews)
"Great counters in the bathroom!! Loved the served breakfast and dinner!"
United States
Wendy
The price is ￥10,125
￥11,391 total
includes taxes & fees
Jun 18 - Jun 19
Super 8 by Wyndham Lake City
Lobby sitting area

Motel 6 – Lake City, Fl – Medical Center

Motel 6 – Lake City, Fl – Medical Center
2.0 star property
Lake City
7.6 out of 10, Good, (177 reviews)
"GOOD STOP FOR ONE NIGHT IF BREAKING UP TRAVEL TIME."
United States
Victoria LS
The price is ￥10,658
￥11,990 total
includes taxes & fees
May 24 - May 25
Motel 6 – Lake City, Fl – Medical Center
Exterior

Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

Holiday Inn Express & Suites Alachua - Gainesville Area by IHG
3.5 star property
Alachua
9.4 out of 10, Exceptional, (1,000 reviews)
"Enjoyed our stay and the friendly staff! Rooms are very clean and comfortable."
United States
Mary Jayne
The price is ￥14,475
￥16,284 total
includes taxes & fees
Jun 14 - Jun 15
Holiday Inn Express & Suites Alachua - Gainesville Area by IHG
Exterior

Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy
2.0 star property
High Springs
10.0 out of 10, Exceptional, (215 reviews)
"fun getaway"
United States
Brigitte
The price is ￥23,666
￥40,010 total
includes taxes & fees
May 27 - May 28
Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy
BBQ/picnic area

Americas Best Value Inn Lake City

Americas Best Value Inn Lake City
2.0 star property
Lake City
8.6 out of 10, Excellent, (1,002 reviews)
"The staff was very nice and polite and it's very simple to get in."
United States
Ricardo
The price is ￥10,665
￥11,999 total
includes taxes & fees
May 25 - May 26
Americas Best Value Inn Lake City
Reception

The Blanche

The Blanche
2.0 star property
Lake City
9.2 out of 10, Wonderful, (187 reviews)
"Great property! Beautiful renovated!"
United States
Brandi
The price is ￥20,520
￥23,084 total
includes taxes & fees
May 25 - May 26
The Blanche
Lobby

Quality Inn White Springs Suwanee

Quality Inn White Springs Suwanee
2.5 star property
Live Oak
7.2 out of 10, Good, (669 reviews)
"It's a great place to stay if you're going to a festival at the spirit of Suwanee music Park "
United States
Elizabeth
The price is ￥11,339
￥12,473 total
includes taxes & fees
Jun 9 - Jun 10
Quality Inn White Springs Suwanee
Suite, Multiple Beds, Accessible, Non Smoking | Pillowtop beds, desk, laptop workspace, iron/ironing board

Comfort Suites Lake City

Comfort Suites Lake City
2.5 star property
Lake City
9.4 out of 10, Exceptional, (1,000 reviews)
"Clean room, Staff helpful, Plenty and up close parking. I would book another stay there if I needed to. "
United States
Roy
The price is ￥17,106
￥19,245 total
includes taxes & fees
May 26 - May 27
Comfort Suites Lake City
Lobby

Regal Inn

Regal Inn
2.5 star property
Lake City
8.6 out of 10, Excellent, (589 reviews)
"older hotel really nicely renovated. Very charmful, comfortable beds. I stayed there because of the reviews and they were accurate. No special amenities' but great value."
United States
William
The price is ￥9,854
￥11,085 total
includes taxes & fees
May 21 - May 22
Regal Inn
Pillowtop beds, in-room safe, desk, blackout drapes

Days Inn by Wyndham Lake City I-75

Days Inn by Wyndham Lake City I-75
2.0 star property
Lake City
7.6 out of 10, Good, (1,001 reviews)
"Great for a short stay and clean"
United States
Brizheet
The price is ￥10,053
￥11,310 total
includes taxes & fees
May 24 - May 25
Days Inn by Wyndham Lake City I-75
Breakfast area

Hampton Inn & Suites Alachua I-75

Hampton Inn & Suites Alachua I-75
2.5 star property
Alachua
9.4 out of 10, Exceptional, (514 reviews)
"Wonderful place to stay"
United States
Tamela
The price is ￥14,717
￥16,556 total
includes taxes & fees
Jun 14 - Jun 15
Hampton Inn & Suites Alachua I-75
1 bedroom, laptop workspace, free WiFi, bed sheets

Vista Verde Farm Retreat

Vista Verde Farm Retreat
2.0 star property
Lake City
9.8 out of 10, Exceptional, (18 reviews)
"Calm peaceful stay, staff was very helpful and attentive. "
United States
Patrick
The price is ￥18,497
￥31,949 total
includes taxes & fees
May 26 - May 27
Vista Verde Farm Retreat
Lobby

Econo Lodge Live Oak

Econo Lodge Live Oak
2.0 star property
Live Oak
7.0 out of 10, Good, (298 reviews)
"Everything about my stay was enjoyable "
United States
David
The price is ￥12,230
￥13,453 total
includes taxes & fees
May 31 - Jun 1
Econo Lodge Live Oak
Indoor pool

Fairfield Inn & Suites Lake City

Fairfield Inn & Suites Lake City
3.0 star property
Lake City
9.0 out of 10, Wonderful, (235 reviews)
"Excellent stay. Great breakfast. "
United States
Janet
The price is ￥20,116
￥22,630 total
includes taxes & fees
May 31 - Jun 1
Fairfield Inn & Suites Lake City
Fountain

BlueGem Motel

BlueGem Motel
2.0 star property
High Springs
9.2 out of 10, Wonderful, (446 reviews)
"Very friendly staff. Clean and very accommodating will definitely be back!"
United States
Jessica
The price is ￥15,255
￥17,162 total
includes taxes & fees
May 26 - May 27
BlueGem Motel
Lobby

Best Western Plus Lake City

Best Western Plus Lake City
2.5 star property
Lake City
9.0 out of 10, Wonderful, (1,069 reviews)
"Great staff, good room, lovely breakfast"
United States
berendina
The price is ￥15,716
￥17,681 total
includes taxes & fees
May 24 - May 25
Best Western Plus Lake City
Double Room, Non Smoking | Laptop workspace, free WiFi

High Springs Country Inn

High Springs Country Inn
2.0 star property
High Springs
8.6 out of 10, Excellent, (28 reviews)
"Very nice and quiet"
United States
Krysten
The price is ￥11,054
￥12,436 total
includes taxes & fees
Jun 9 - Jun 10
High Springs Country Inn
Exterior

La Quinta Inn & Suite by Wyndham Lake City

La Quinta Inn & Suite by Wyndham Lake City
2.5 star property
Lake City
8.6 out of 10, Excellent, (1,101 reviews)
"Nice hotel, nice price - recommend."
United States
Michael D
The price is ￥16,438
￥18,493 total
includes taxes & fees
May 31 - Jun 1
La Quinta Inn & Suite by Wyndham Lake City
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Learn more about O Brien

Escape to this rural Florida gem where the Suwannee River offers peaceful kayaking trips and fishing adventures. Nearby Spirit of the Suwannee Music Park hosts live concerts, while O'Brien's local farms welcome visitors for fresh produce and family-friendly activities.

See all hotels in O Brien
kayakers at Rock Bluff Spring on the Suwanneee River, Gilchrist County, Florida

Top O Brien Hotel Reviews

Days Inn by Wyndham Lake City I-75

Days Inn by Wyndham Lake City I-75

10/10 Excellent
"One of the best rooms I’ve stayed in for the price! "
Wesley 1-night trip
Posted 5 hours ago
Days Inn by Wyndham Lake City I-75

More cheap stays in O Brien

Motel 6 – Lake City, Fl – Medical Center

Motel 6 – Lake City, Fl – Medical Center

3340 W US Highway 90 Lake City FL
The price is ￥10,658 per night from May 24 to May 25
￥10,658
￥11,990 total
May 24 - May 25
includes taxes & fees
7.6/10 Good! (177 reviews)

Frequently asked questions

Where is the best place to stay in O Brien?
La Quinta Inn & Suite by Wyndham Lake City, located 18.2 mi (29.3 km) from the heart of O Brien, is a top choice for your stay based on our traveler data. Other good choices for your visit to the area are Holiday Inn Express & Suites Alachua - Gainesville Area by IHG and Americas Best Value Inn Lake City. See all available top hotels, or vacation rentals in O Brien.
What's the top vacation rental in O Brien?
Royal Springs Riverfront Retreat on 3 acres, kayak/canoe, boat ramp, huge decks!: Visitors like this O Brien vacation home rental. It is located on the beach and has a balcony, a garden, and a barbecue grill to put you at ease in your new surroundings. It has 3 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. You and your friends and family can relax into your vacation with amenities like a selection of games. See all vacation rentals in O Brien.
If I need to cancel my hotel reservation in O Brien, will I receive a refund?
Yes! You'll find that most hotel reservations are fully refundable as long as you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If your reservation is non-refundable, it may still be possible to cancel it and get a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in O Brien.
Where can I learn more about changing or cancelling my trip to O Brien?
To access more information about picking new dates or cancelling your trip to O Brien, click here.
Where is the best hotel to stay near Ichetucknee Springs State Park?
Escape to Nature - 2 miles from Ichetucknee park is one of the top choices for your stay based on our traveler data, and this property features in-room kitchens and fireplaces. It's located 2.3 mi (3.8 km) from Ichetucknee Springs State Park. Another good choice is A Riverview of a Magical Sunrise every morning, located 5.6 mi (9.1 km) away.
What are some accommodations with pools in O Brien?
La Quinta Inn & Suite by Wyndham Lake City: Provides on-the-go, an indoor pool, and free self parking. Royal Springs Riverfront Retreat on 3 acres, kayak/canoe, boat ramp, huge decks! and Little River Spring Cave divers poolside Hideaway are two additional hotels that feature an onsite pool. View all hotels with pools in O Brien.
What's the best hotel for staying near Gainesville Regional Airport (GNV)?
Hampton Inn & Suites Gainesville Downtown is one of the top choices for your stay and is a popular hotel, featuring free breakfast and an outdoor pool. It's located 3.7 mi (6 km) from Gainesville Regional Airport. Other good choices close to the airport include Sweetwater Branch Inn and Travelers Inn.
How is it to stay in O Brien?
Visitors to O Brien are sure to find plenty to explore and enjoy. In O Brien, there are 12 hotels and other accommodations to choose from. Find out more about O Brien.
What should I see while I'm in O Brien?
Natural beauty is on display at Suwannee River, Ichetucknee River, and Ichetucknee Springs State Park. You'll also find Troy Spring State Park and Wes Skiles Peacock Springs State Park in the area. Check out what more to see and do in Expedia's O Brien guide.
What's the seasonal weather like in O Brien?
The hottest months are usually July and August with an average temp of 80°F, while the coldest months are January and February with an average of 58°F. Average annual precipitation for O Brien is 50 inches.

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