A cannon on a brick platform by a river, with a steamboat in the background.

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Jul 17 - Jul 19
Next weekend
Jul 24 - Jul 26

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Our top choices for New Madrid hotels

Exterior

Holiday Inn Express & Suites Sikeston Southwest by IHG

Holiday Inn Express & Suites Sikeston Southwest by IHG
2.5 star property
Sikeston
8.6 out of 10, Excellent, (479 reviews)
"Nice!"
United States
theresa
The price is ļæ„14,838
ļæ„16,800 total
includes taxes & fees
Aug 2 - Aug 3
Holiday Inn Express & Suites Sikeston Southwest by IHG
Exterior

Hampton Inn Sikeston

Hampton Inn Sikeston
2.5 star property
Sikeston
9.0 out of 10, Wonderful, (592 reviews)
"Staff were great at Check in, room was clean, breakfast was good."
United States
Brandi
The price is ļæ„17,149
ļæ„19,417 total
includes taxes & fees
Aug 15 - Aug 16
Hampton Inn Sikeston
Room, 1 Queen Bed, Non Smoking | Desk, laptop workspace, blackout drapes, WiFi (free)

Super 8 By Wyndham Marston

Super 8 By Wyndham Marston
2.0 star property
Marston
8.0 out of 10, Very Good, (68 reviews)
"Clean room, The receptionist very friendly, good parking."
United States
Temera
The price is ļæ„13,423
ļæ„15,332 total
includes taxes & fees
Jul 18 - Jul 19
Super 8 By Wyndham Marston
Premier Room, 1 Bedroom, Non Smoking | Desk, free WiFi, bed sheets

New Orleans Inn Portageville

New Orleans Inn Portageville
2.5 star property
Portageville
8.0 out of 10, Very Good, (786 reviews)
"Great stay with Great people, very clean and welcoming"
United States
Mircea
The price is ļæ„8,825
ļæ„9,529 total
includes taxes & fees
Aug 2 - Aug 3
New Orleans Inn Portageville
Standard Room, 2 Double Beds, Non Smoking | Blackout drapes, iron/ironing board (on request), WiFi (free)

Reelfoot Lake Inn

Reelfoot Lake Inn
2.0 star property
Tiptonville
7.2 out of 10, Good, (501 reviews)
"The lake view was beautiful and staff was amazing"
United States
Richard
The price is ļæ„9,889
ļæ„11,348 total
includes taxes & fees
Jul 31 - Aug 1
Reelfoot Lake Inn
Property amenity

Fairfield Inn & Suites by Marriott Sikeston

Fairfield Inn & Suites by Marriott Sikeston
3.0 star property
Sikeston
9.4 out of 10, Exceptional, (99 reviews)
"Great stay, kind staff, very clean property."
United States
Joni
The price is ļæ„17,833
ļæ„20,191 total
includes taxes & fees
Aug 16 - Aug 17
Fairfield Inn & Suites by Marriott Sikeston
Free WiFi, bed sheets

Travel Inn Marston I-55 by Hotel O

Travel Inn Marston I-55 by Hotel O
2.5 star property
Marston
6.0 out of 10, (125 reviews)
"Quiet safe area."
United States
Frank
The price is ļæ„9,220
ļæ„11,454 total
includes taxes & fees
Aug 15 - Aug 16
Travel Inn Marston I-55 by Hotel O
Property amenity

TownePlace Suites by Marriott Sikeston

TownePlace Suites by Marriott Sikeston
3.0 star property
Sikeston
9.2 out of 10, Wonderful, (18 reviews)
"This hotel was great. Good location. Awesome staff. Hopefully I get the opportunity to stay here again."
United States
Jason
The price is ļæ„17,671
ļæ„20,008 total
includes taxes & fees
Aug 16 - Aug 17
TownePlace Suites by Marriott Sikeston
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular New Madrid attractions

New Madrid Historical Museum

8.2/10 (36 reviews)
Explore the powerful 1811-1812 earthquakes that reshaped America's heartland at this historic museum. Engage with knowledgeable curators while viewing artifacts from Native American cultures and the Civil War.
See properties

Learn more about New Madrid

The New Madrid Historical Museum reveals the dramatic story of the 1811-1812 earthquakes that changed the course of the Mississippi River. Enjoy peaceful fishing at Donaldson Point Conservation Area or take a sunset river cruise to spot bald eagles along the mighty Mississippi.

See all hotels in New Madrid
A cannon on a brick platform by a river, with a steamboat in the background.

Top New Madrid Hotel Reviews

Hampton Inn Sikeston

Hampton Inn Sikeston

10/10 Excellent
"My 21 year old son stayed at this Hampton Inn on his way back to college in IL. He enjoyed the gym, the indoor pool, the large selection of breakfast items, and the close proximity to I-55. The room was clean and the staff was friendly, even to a 21 year old young man traveling alone. Thank you for a wonderfully positive experience!"
Caiden 1-night trip
Posted 9 hours ago
Hampton Inn Sikeston

More cheap stays in New Madrid

New Orleans Inn Portageville

New Orleans Inn Portageville

600 US-61 Portageville MO
The price is ļæ„8,825 per night from Aug 2 to Aug 3
ļæ„8,825
ļæ„9,529 total
Aug 2 - Aug 3
includes taxes & fees

Frequently asked questions

Where is the best place for a stay in New Madrid?
Hampton Inn Sikeston, located 18.9 mi (30.4 km) from the heart of New Madrid, is a top choice for your stay based on our traveler data. Other good options for your trip to the area are Holiday Inn Express & Suites Sikeston Southwest by IHG and Fairfield Inn & Suites by Marriott Sikeston. See all available top hotels, or vacation rentals in New Madrid.
What are some of the best vacation home rentals that New Madrid has to offer?
Spacious 3-bedroom 2 story house in New Madrid near boat ramp with a toy room!: This New Madrid vacation home rental offers a garden, a selection of games, and air-conditioning to help you feel perfectly comfortable in your new surroundings. Kitchen amenities include a dishwasher, a fridge, and a stovetop. See all vacation rentals in New Madrid.
If I need to cancel my hotel reservation in New Madrid, will I receive a refund?
Yes, most hotel room reservations are refundable provided that you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of the scheduled arrival. If you have a non-refundable reservation, it might still be possible to cancel it and be given a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in New Madrid.
Where can I learn more about changing or cancelling my trip to New Madrid?
For additional details about updating your trip to New Madrid or cancelling it, head over to our customer service page.
What's the best hotel to stay with easy access to New Madrid Historical Museum?
Travel Inn is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and free parking. You'll find it 6.8 mi (10.9 km) from New Madrid Historical Museum. Other good options around the area include Reelfoot Lake Inn and Lodge that sleeps 16! Ideal for Fishermen, Family reunions, Hunters and Tourist!.
What about the best place to stay near Hunter-Dawson State Historic Site?
One of the top choices for your stay is Travel Inn, located 7.2 mi (11.6 km) from Hunter-Dawson State Historic Site, and this hotel offers free breakfast and free parking. Reelfoot Lake Inn and Lodge that sleeps 16! Ideal for Fishermen, Family reunions, Hunters and Tourist! are other good choices within the area.
What's the best accommodation near Cairo Regional Airport (CIR)?
Quality Inn Cairo I-57 is one of the top choices for your stay and is a popular hotel, featuring free breakfast and free WiFi. It's located 2.1 mi (3.3 km) from Cairo Regional Airport.
What is staying in New Madrid like?
Visitors can enjoy all that New Madrid has to offer including the parks and museums. There are 59 hotels and other accommodations in the surrounding area. Find out more about New Madrid.
What are the top places to visit in New Madrid?
Cultural venues include New Madrid Historical Museum and Hunter-Dawson State Historic Site. A couple of additional sights to add to your agenda are Mississippi River and River Ridge Winery. Check out what more to see and do in Expedia's New Madrid guide.
What's the weather like in New Madrid?
The hottest months are usually July and August with an average temp of 77Ā°F, while the coldest months are January and February with an average of 42Ā°F. Average annual precipitation for New Madrid is 60 inches.