Find hotels in New Madrid, MO from ￥9,786

Hampton Inn Sikeston, located 19 mi (30.5 km) from the heart of New Madrid, is a top choice for your stay based on our traveler data. Other good options for your trip to the area are Fairfield Inn & Suites by Marriott Sikeston and Holiday Inn Express & Suites Sikeston Southwest by IHG. See all available top hotels, or vacation rentals in New Madrid.

Duck Hunting, Fishing or Relaxing Family Vacation: This vacation home rental outside of New Madrid is located on a lake and has a patio, a garden, and a barbecue grill to put you at ease in your new surroundings. It has 3 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. See all vacation rentals in New Madrid.

Yes, most hotel room reservations are refundable provided that you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of the scheduled arrival. If you have a non-refundable reservation, it might still be possible to cancel it and be given a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in New Madrid.

For additional details about updating your trip to New Madrid or cancelling it, head over to our customer service page.

Travel Inn is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and free parking. You'll find it 6.8 mi (10.9 km) from New Madrid Historical Museum. Other good options around the area include Reelfoot Lake Inn and Lodge that sleeps 16! Ideal for Fishermen, Family reunions, Hunters and Tourist!.

One of the top choices for your stay is Travel Inn, located 7.2 mi (11.6 km) from Hunter-Dawson State Historic Site, and this hotel offers free breakfast and free parking. Reelfoot Lake Inn and Lodge that sleeps 16! Ideal for Fishermen, Family reunions, Hunters and Tourist! are other good choices within the area.

Quality Inn Cairo I-57 is one of the top choices for your stay and is a popular hotel, featuring free breakfast and free WiFi. It's located 2.1 mi (3.3 km) from Cairo Regional Airport.

Visitors can enjoy all that New Madrid has to offer including the parks and museums. There are 49 hotels and other accommodations in the surrounding area. Find out more about New Madrid.

Cultural venues include New Madrid Historical Museum and Hunter-Dawson State Historic Site. A couple of additional sights to add to your agenda are Mississippi River and River Ridge Winery. Check out what more to see and do in Expedia's New Madrid guide.

The hottest months are usually July and August with an average temp of 77°F, while the coldest months are January and February with an average of 42°F. Average annual precipitation for New Madrid is 60 inches.