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Compare 2,608 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

MONTANA ECO HOTEL

2.0 star property
El Santuario
The price is ¥21,278
¥21,278 total
Dec 6 - Dec 7
MONTANA ECO HOTEL

Isak Hotel & Golf Airport

3.0 star property
Rionegro
9.4 out of 10, Exceptional, (537)
"Staff and the property is amazing "
United States
Denis
The price is ¥8,384
¥8,384 total
Dec 28 - Dec 29
Isak Hotel & Golf Airport

Dann Carlton Medellin Hotel

4.5 star property
El Poblado
8.8 out of 10, Excellent, (1646)
"Excellent location, nice room, attentive staff and a great breakfast "
United States
Vanessa
The price is ¥14,227
¥14,227 total
Dec 8 - Dec 9
Dann Carlton Medellin Hotel

Hunters By Jalo

3.0 star property
El Poblado
9.2 out of 10, Wonderful, (184)
"Really nice hotel! "
United States
IBRAHIM
The price is ¥9,858
¥9,858 total
Dec 15 - Dec 16
Hunters By Jalo

BubbleSky Glamping Guatapé

3.0 star property
Guatapé
9.0 out of 10, Wonderful, (86)
"Great place "
United States
George
BubbleSky Glamping Guatapé

Hotel Los Recuerdos

3.5 star property
Guatapé
8.2 out of 10, Very Good, (581)
"The staff were great"
United States
Jonathan
The price is ¥37,337
¥37,337 total
Jan 2 - Jan 3, 2026
Hotel Los Recuerdos

The Brown, Guatape, Autograph Collection

4.0 star property
Guatapé
9.2 out of 10, Wonderful, (397)
"Great hotel, great property, excellent food, beautiful property and the staff was so friendly and kind! "
United States
Joel
The price is ¥28,845
¥28,845 total
Dec 11 - Dec 12
The Brown, Guatape, Autograph Collection

Porto Marina Hotel

3.5 star property
El Peñol
9.2 out of 10, Wonderful, (96)
"The apartment we had was amazing! The staff was very welcoming and lovely, and they have 2 amazing dogs ❤️🐕"
United Kingdom
Agne
Porto Marina Hotel

Hotel Verony Guatape

3.0 star property
Guatapé
8.2 out of 10, Very Good, (114)
"Exelente hotel , "
Mexico
Williams
Hotel Verony Guatape

Tau House

4.0 star property
Guatapé
9.4 out of 10, Exceptional, (116)
"Nice place, great statf"
Canada
Burke
The price is ¥30,031
¥30,031 total
Dec 12 - Dec 13
Tau House

MYLOS Hotel Boutique

3.0 star property
Guatapé
8.4 out of 10, Very Good, (8)
"An amazing experience. The whole staff super friendly. First time in Colombia. For sure I’ll be back. Till the next time "
United States
anthony
The price is ¥31,851
¥31,851 total
Dec 8 - Dec 9
MYLOS Hotel Boutique

Alfahar Hotel

3.0 star property
El Carmen de Viboral
9.6 out of 10, Exceptional, (19)
"great hotel, good staff "
United States
matania
Alfahar Hotel

Casa Rose Hotel

3.5 star property
El Carmen de Viboral
9.4 out of 10, Exceptional, (48)
"Staff was welcoming, kind, and serviceable. The hotel's location was very convenient. The amenities and rooms were comfortable, clean and spacious"
United States
Paula
The price is ¥8,524
¥8,524 total
Jan 2 - Jan 3, 2026
Casa Rose Hotel

Hotel Santiago de Arma

3.0 star property
Rionegro
9.2 out of 10, Wonderful, (897)
"Clean and close to the airport "
United States
Andy
Hotel Santiago de Arma

Movich Hotel Las Lomas

4.0 star property
Rionegro
9.0 out of 10, Wonderful, (1003)
"This is a great family hotel, they have a very nice restaurant, the food was excellent. The outdoor space is very nice, beautiful pool, The staff was very friendly and the room was clean and comfortable "
Canada
Joe
The price is ¥25,534
¥25,534 total
Dec 12 - Dec 13
Movich Hotel Las Lomas

Hotel Lagoon

3.5 star property
Rionegro
9.2 out of 10, Wonderful, (295)
"Nice property, very good food, very relaxing."
United States
Kevin
The price is ¥24,550
¥24,550 total
Dec 24 - Dec 25
Hotel Lagoon

TEVA Glamping & Retreat

3.5 star property
Rionegro
9.2 out of 10, Wonderful, (107)
"Love coming here "
United States
Claudia M
TEVA Glamping & Retreat

MG Hotels & Suites

3.5 star property
Rionegro
8.8 out of 10, Excellent, (213)
"It was a pleasant surprise. The staff is very attentive and efficient. The restaurant on the premises was excellent. "
United States
Carlos
The price is ¥21,865
¥21,865 total
Dec 7 - Dec 8
MG Hotels & Suites

Travelers Rio Verde Living Suites

3.5 star property
Rionegro
8.2 out of 10, Very Good, (461)
"Good property. "
United States
Ruth Marcela
Travelers Rio Verde Living Suites

Novotel Medellín El Tesoro

4.5 star property
El Poblado
9.2 out of 10, Wonderful, (1347)
"Incredible place "
United States
Cindy
The price is ¥16,417
¥16,417 total
Jan 3 - Jan 4, 2026
Novotel Medellín El Tesoro
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

Where is the best place to stay in El Santuario?
Located 22.1 mi (35.5 km) from the heart of El Santuario, Heiss Hotel By Jalo is a top choice for your stay based on our traveler data. Other good choices for your visit to the area are Calle Flora Hotel by Jalo and NH Collection Medellín Royal. See all available top hotels, or vacation rentals in El Santuario.
What's the top vacation rental that El Santuario has to offer?
EP Casa Uribe Architecture Art & Nature: This vacation home rental outside of El Santuario is located in a shopping district and has an outdoor pool, a balcony, and laundry facilities to put you at ease in your new surroundings. Kitchen amenities include a dishwasher, a fridge, and a stovetop. See all vacation rentals in El Santuario.
If I need to cancel my hotel reservation in El Santuario, will I receive a refund?
Yes, most room reservations are fully refundable if cancelled before the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your arrival date. If you booked a non-refundable reservation, you might still have the option to cancel and get a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in El Santuario.
Where can I learn more about changing or cancelling my trip to El Santuario?
To access more information about updating your trip to El Santuario or cancelling it, click here.
What's it like staying in El Santuario?
Visitors are sure to enjoy all that El Santuario has to offer. In El Santuario, there are 2 hotels and other accommodations to choose from. Find out more about El Santuario.
What are the top places to visit in El Santuario?
Places to visit in the wider area include San Nicolás Mall, Rock of Guatapé, and Parque Comfama. You'll also find Piedra del Marial and Llanogrande Mall in the area. Check out what more to see and do in Expedia's El Santuario guide.
What's the seasonal weather like in El Santuario?
The hottest months are usually August and September with an average temp of 63°F, while the coldest months are January and July with an average of 63°F. The rainiest months in El Santuario are April, May, October, and November, with each month seeing an average of 17 inches of rainfall.

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