Find & Book the Best Hotels in Wayne County for 2026

Top Cities in Wayne County

Large boulders on a rocky landscape with a cloudy sky.

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Our top choices for Wayne County hotels

A rustic cabin with a metal roof, surrounded by a wooden deck and picnic tables, set in a forested area.

1. Lake Wappapello

Williamsville

Tonya

￥14,990 total

includes taxes & fees

Oct 11 - Oct 12

A wooden deck with steps leading to a house, surrounded by trees.

2. Get Away Acres 1/2 mile off highway 60 extra sanitized

Ellsinore

Anonymous traveler

￥20,690 total

includes taxes & fees

Oct 8 - Oct 9

A kitchen with wooden cabinets, a microwave, a coffee maker, a stove, and a sink.

3. Clearwater Lake, cabin minutes from Bluff View Marina & boat dock

Piedmont

Steve A.

￥23,192 total

includes taxes & fees

Oct 15 - Oct 16

A small, single-story cabin with a metal roof, surrounded by a grassy yard and dense trees.

4. Fall Getaway Cabin Bordering Mark Twain National Forest w/Fire Pit & Trails

Mill Spring

￥27,424 total

includes taxes & fees

Oct 8 - Oct 9

A cozy cabin-style room with a wooden interior, a sofa, a dining table, and a kitchen area.

5. Cozy hobby farm cabin under the stars!

Patterson

Wyatt S.

￥19,088 total

includes taxes & fees

Nov 2 - Nov 3

A rustic log cabin with a stone foundation, surrounded by trees and a wooden fence.

6. Sam A Baker State Park

Patterson

Charlie

￥22,630 total

includes taxes & fees

Oct 14 - Oct 15

A Master Lock combination lock attached to a door.

7. Cabin 1 queen bed with a separate bedroom with a double bed

Piedmont

Tonya W.

A rustic cabin interior with a wooden ceiling, a blue door, a television mounted on a wooden shelf, and a dining table with chairs.

8. Mtn-View Cabin w/ Deck & Fire Pit in Des Arc!

Des Arc

PEGGY

A modern kitchen with white cabinets, a central island with stools, and a sign reading "BEACH HOUSE".

9. 1/4 Mile To The Boat Launch & Beach 2 miles the Camp! Free WiFi, beautiful space

Wappapello

Richard L.

A campfire surrounded by benches in a wooded park area.

10. Brown's Lake House, Family-Friendly 2 Bedroom Retreat Near Lake Wappapello

Wappapello

Shea E.

￥38,515 total

includes taxes & fees

Nov 2 - Nov 3

11. Mtn-view Cabin w/ Deck & Fire Pit in Des Arc!

Des Arc

A covered outdoor area with a table and chairs, a metal chair, and a trash can.

12. Cabin near Clearwater Lake

Piedmont

A cozy cabin-style room with a wooden ceiling, a green sofa, a small kitchen area, and a pet bed.

13. Camp Minnow Beach House

Wappapello

Jonathan G.

A kitchen with a black microwave, stove, and refrigerator, with a coffee maker and a sink.

14. Creekside Family camping near Clearwater Lake!

Piedmont

"I would have rated higher, however this is actually a refurbished camper, snd these are newer hosts. There aren't enough outlets and the kitchen outlet for the coffee maker does not work. Also, the shower drain did not work, however the owners were able to fix it almost immediately when we contacted them. Overall, it's a nice, updated camper, the location was perfect for our needs and the hosts were responsive to our needs. We would likely stay again."

Trisha

A modern kitchen with dark cabinetry, a stainless steel refrigerator, a wooden dining table, and a clock on the wall.

15. Ride Trails or go fishing near Clearwater lake. No cleaning fees, pet friendly

Piedmont

Mike A.

￥30,029 total

includes taxes & fees

Oct 8 - Oct 9

A covered outdoor seating area with two wooden chairs, a table with drinks, and a lamp post.

16. Sunshine Shack at Clearwater Lake (sleeps 6)

Piedmont

"The Sunshine Shack is incredibly cute and well decorated, and it also has a number of extremely thoughtful and thorough touches that made our weekend there absolutely wonderful!The screen porch in the back is also amazing and absolutely outstanding. This is such a wonderful place to stay, and its proximity to the Black River is unparalleled. Highly recommend and will definitely stay here again many times over!Thank you so much!"

Matt R.

A spacious living area with a leather couch, dining table, and chairs, large windows, and a view of trees.

17. Riverfront Retreat w/ Porch & Views in Des Arc!

Des Arc

A kitchen with wooden cabinets, a white microwave, a stove, and a coffee maker.

18. Cabin 2 2 double beds

Piedmont

meghan

A kitchen with wooden cabinets, a stainless steel refrigerator, a stove, and a window.

19. Hunting / Fishing Cabin at Lake Wappapello

Williamsville

￥39,150 total

includes taxes & fees

Oct 8 - Oct 9

20. Riverfront Retreat w/ Porch & Views in Des Arc!

Des Arc

Cheryl S.

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Top Wayne County Hotel Reviews

Hampton Inn Poplar Bluff

10/10 Excellent

"Clean rooms, efficient staff, lovely breakfast. I appreciated the hotel sending a text after I checked in; it made it very easy to get questions answered."