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Our top choices for Cherokee Seneca hotels

21c Museum Hotel Louisville

21c Museum Hotel Louisville
4.5 star property
Downtown Louisville, 7 km from Cherokee Seneca
9.2 out of 10, Wonderful, (1,000 reviews)
"Excellent place. "
United States
Anatole
The price is ¥22,179
¥26,887 total
includes taxes & fees
Jan 30 - Jan 31
21c Museum Hotel Louisville

Holiday Inn Express & Suites Louisville Downtown by IHG

Holiday Inn Express & Suites Louisville Downtown by IHG
2.5 star property
Downtown Louisville, 7.1 km from Cherokee Seneca
8.8 out of 10, Excellent, (1,681 reviews)
"Room was clean and the beds were very comfortable. Would definitely stay here again."
United States
Talva
The price is ¥13,004
¥15,300 total
includes taxes & fees
Jan 25 - Jan 26
Holiday Inn Express & Suites Louisville Downtown by IHG

SpringHill Suites by Marriott Louisville Downtown

SpringHill Suites by Marriott Louisville Downtown
3.0 star property
Downtown Louisville, 5.9 km from Cherokee Seneca
8.4 out of 10, Very Good, (1,002 reviews)
"Great location, spacious room, friendly staff"
United States
Valeriia
The price is ¥15,970
¥18,792 total
includes taxes & fees
Jan 20 - Jan 21
SpringHill Suites by Marriott Louisville Downtown

Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham
4.0 star property
Downtown Louisville, 6.5 km from Cherokee Seneca
9.0 out of 10, Wonderful, (3,986 reviews)
"Great stay"
United States
Carlos
The price is ¥21,349
¥25,120 total
includes taxes & fees
Jan 27 - Jan 28
Galt House Hotel Trademark Collection by Wyndham

Hyatt Regency Louisville

Hyatt Regency Louisville
4.0 star property
Downtown Louisville, 6.4 km from Cherokee Seneca
8.8 out of 10, Excellent, (1,002 reviews)
"Great hotel close to 4th street. Overall nice stay. "
United States
Collin
The price is ¥21,346
¥25,116 total
includes taxes & fees
Jan 26 - Jan 27
Hyatt Regency Louisville

Tru by Hilton Shepherdsville Louisville South

Tru by Hilton Shepherdsville Louisville South
2.5 star property
19.1 km from Cherokee Seneca
9.2 out of 10, Wonderful, (855 reviews)
"Very friendly staff, very clean and comfy rooms"
United States
Trevor
The price is ¥13,949
¥15,525 total
includes taxes & fees
Jan 24 - Jan 25
Tru by Hilton Shepherdsville Louisville South

Fairfield Inn & Suites by Marriott Louisville Airport

Fairfield Inn & Suites by Marriott Louisville Airport
2.5 star property
7.3 km from Cherokee Seneca
8.8 out of 10, Excellent, (688 reviews)
"Staff was amazing, hotel was great."
United States
Rickey
The price is ¥14,705
¥17,302 total
includes taxes & fees
Jan 23 - Jan 24
Fairfield Inn & Suites by Marriott Louisville Airport

Hilton Garden Inn Louisville Downtown

Hilton Garden Inn Louisville Downtown
3.5 star property
Downtown Louisville, 6.4 km from Cherokee Seneca
8.4 out of 10, Very Good, (1,000 reviews)
"Clean, great location and amazing customer service "
United States
Jamie
The price is ¥14,720
¥17,321 total
includes taxes & fees
Jan 25 - Jan 26
Hilton Garden Inn Louisville Downtown

Courtyard by Marriott Louisville Airport

Courtyard by Marriott Louisville Airport
3.0 star property
7.1 km from Cherokee Seneca
9.2 out of 10, Wonderful, (365 reviews)
"Amenities, restaurants, location, room was nice "
United States
Anitra
The price is ¥16,919
¥19,907 total
includes taxes & fees
Jan 20 - Jan 21
Courtyard by Marriott Louisville Airport

Omni Louisville Hotel

Omni Louisville Hotel
4.0 star property
Downtown Louisville, 6.2 km from Cherokee Seneca
9.2 out of 10, Wonderful, (1,761 reviews)
"Beautiful, spacious hotel. Spotless room, kind and helpful staff."
United States
Gizella
The price is ¥26,439
¥31,108 total
includes taxes & fees
Jan 20 - Jan 21
Omni Louisville Hotel

Homewood Suites by Hilton Louisville Downtown, KY

Homewood Suites by Hilton Louisville Downtown, KY
3.0 star property
Downtown Louisville, 6.9 km from Cherokee Seneca
9.2 out of 10, Wonderful, (1,002 reviews)
"Very friendly and clean! Great stay! "
United States
Jackie
The price is ¥16,776
¥19,737 total
includes taxes & fees
Feb 1 - Feb 2
Homewood Suites by Hilton Louisville Downtown, KY

Marriott Louisville East

Marriott Louisville East
4.0 star property
Jeffersontown, 9.9 km from Cherokee Seneca
9.0 out of 10, Wonderful, (1,001 reviews)
"Great stay"
United States
Brad
The price is ¥17,337
¥20,398 total
includes taxes & fees
Jan 23 - Jan 24
Marriott Louisville East

Drury Inn & Suites Louisville North

Drury Inn & Suites Louisville North
3.0 star property
12.5 km from Cherokee Seneca
9.6 out of 10, Exceptional, (1,001 reviews)
"Excellent place to stay."
United States
Robert
The price is ¥15,857
¥18,658 total
includes taxes & fees
Jan 22 - Jan 23
Drury Inn & Suites Louisville North

Hilton Garden Inn Louisville Mall of St. Matthews

Hilton Garden Inn Louisville Mall of St. Matthews
3.0 star property
St. Matthews, 5.2 km from Cherokee Seneca
9.2 out of 10, Wonderful, (886 reviews)
"Great view, comfortably slept and amazing staff"
United States
Rebecca
The price is ¥15,053
¥17,711 total
includes taxes & fees
Jan 23 - Jan 24
Hilton Garden Inn Louisville Mall of St. Matthews

Aloft Louisville Downtown

Aloft Louisville Downtown
3.0 star property
Downtown Louisville, 6.1 km from Cherokee Seneca
9.0 out of 10, Wonderful, (1,002 reviews)
"Great room and location and always a plus when pets can stay for free!"
United States
Elizabeth
The price is ¥15,938
¥18,752 total
includes taxes & fees
Feb 1 - Feb 2
Aloft Louisville Downtown

Hampton Inn Simpsonville

Hampton Inn Simpsonville
2.5 star property
29.6 km from Cherokee Seneca
9.4 out of 10, Exceptional, (912 reviews)
"Would stay again"
United States
Chris
The price is ¥14,133
¥15,730 total
includes taxes & fees
Jan 25 - Jan 26
Hampton Inn Simpsonville

Fairfield Inn & Suites by Marriott Louisville Downtown

Fairfield Inn & Suites by Marriott Louisville Downtown
2.5 star property
Downtown Louisville, 6 km from Cherokee Seneca
8.4 out of 10, Very Good, (1,001 reviews)
"Great stay!!!"
United States
Bridget
The price is ¥14,705
¥17,302 total
includes taxes & fees
Jan 23 - Jan 24
Fairfield Inn & Suites by Marriott Louisville Downtown

Embassy Suites Louisville Downtown

Embassy Suites Louisville Downtown
4.0 star property
Downtown Louisville, 6.4 km from Cherokee Seneca
9.0 out of 10, Wonderful, (1,140 reviews)
"Great room and breakfast. Close to several nice restaurants."
United States
Crystal
The price is ¥19,897
¥23,411 total
includes taxes & fees
Jan 24 - Jan 25
Embassy Suites Louisville Downtown

Derby City Gaming & Hotel - A Churchill Downs Property

Derby City Gaming & Hotel - A Churchill Downs Property
4.0 star property
6 km from Cherokee Seneca
9.4 out of 10, Exceptional, (1,758 reviews)
"Rooms are very nice we had a great time "
United States
william
Derby City Gaming & Hotel - A Churchill Downs Property

Cambria Hotel Louisville Downtown-Whiskey Row

Cambria Hotel Louisville Downtown-Whiskey Row
3.0 star property
Downtown Louisville, 5.8 km from Cherokee Seneca
9.4 out of 10, Exceptional, (1,002 reviews)
"Enjoyed our stay."
United States
Christian
The price is ¥16,366
¥19,256 total
includes taxes & fees
Feb 17 - Feb 18
Cambria Hotel Louisville Downtown-Whiskey Row
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Cherokee Seneca

Find the best Cherokee Seneca areas and neighborhoods for the activities you enjoy most.

Downtown Louisville

Explore "Museum Row" in the West Main District, catch a game at Louisville Slugger Field, or stroll across the pedestrian-only Big Four Bridge. Enjoy diverse attractions, restaurants, and the Louie Link skywalk.

St. Matthews

Major shopping destination with the fifth-largest mall in Kentucky, Mall St. Matthews, and smaller centers along Shelbyville Road. Don't miss the historic St. Matthew's Episcopal Church and Holy Trinity.

Fairgrounds

While visiting Fairgrounds, you might make a stop by sights like Freedom Hall and Kentucky Kingdom.

Jeffersontown

Jeffersontown is known for its abundant dining options, and you can plan a trip to Jeffersontown Commons Shopping Center and Bluegrass Indoor Karting while you're in town.

Old Louisville

Boasting Victorian architecture and the highest concentration of stained glass windows in residential homes, Old Louisville offers a walkable neighborhood with pedestrian-only streets, diverse dining options, and attractions like Central Park and the Conrad-Caldwell House.

Top Cherokee Seneca Hotel Reviews

Frequently asked questions

What is Cherokee Seneca like?
You'll be sure to have fun visiting Louisville's Cherokee Seneca neighborhood.
If I need to cancel my hotel reservation in Cherokee Seneca, will I receive a refund?
Yes, you'll find most hotel room reservations are fully refundable provided that you cancel before the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If you have a reservation that's non-refundable, it may still be possible to cancel it and be given a refund within 24 hours of booking. Add your dates and click on "Search", then use the "fully refundable" filter to review top deals in Cherokee Seneca.
Where can I learn more about changing or cancelling my trip to Cherokee Seneca?
To find more details about changing or cancelling your trip to Cherokee Seneca, head over to our customer service page.
What is there to do around this Louisville neighborhood?
Peterson-Dumesnil House, Historic Frankfort Avenue, and Colonel Sanders' Grave are just a few of the places to visit in and around Cherokee Seneca. Muhammad Ali Gravesite and Mid City Mall Shopping Center are also worth a visit when you're out sightseeing in Louisville.

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