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Sep 5 - Sep 7
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Sep 12 - Sep 14
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Sep 26 - Sep 28
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Oct 24 - Oct 26

B&B in Cairo

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Recommended hotels in Cairo

La Center Motel
Basic Double Room | 1 bedroom, free WiFi

La Center Motel

2.0 star property
7.8 out of 10, Good, (14)
"Front desk staff was amazing. Room was comfy and quiet! Clean! Husband and I needed a place to crash on our long ride home and this motel did not disappoint!"
La Center Motel
Quality Inn Cairo I-57
Lobby

Quality Inn Cairo I-57

2.5 star property
6.6 out of 10, (264)
"The hotel is in need of some serious upkeep and cleaning. It is in fairly poor condition, but it the only hotel in town."
The price is ￥10,185
￥11,304 total
includes taxes & fees
Sep 8 - Sep 9
Quality Inn Cairo I-57
Super 8 by Wyndham Charleston/Sikeston East MO
Front of property - evening/night

Super 8 by Wyndham Charleston/Sikeston East MO

2.0 star property
6.6 out of 10, (585)
"Rooms was clean "
The price is ￥8,523
￥9,458 total
includes taxes & fees
Sep 10 - Sep 11
Super 8 by Wyndham Charleston/Sikeston East MO
Cozy cabins on beautiful Horseshoe Lake
Dining

Cozy cabins on beautiful Horseshoe Lake

9.8 out of 10, Exceptional, (34)
"great stay, would book again if ever in the area. Thanks!"
The price is ￥15,261
￥19,300 total
includes taxes & fees
Sep 2 - Sep 3
Cozy cabins on beautiful Horseshoe Lake
Quality Inn Charleston - Sikeston
Desk, laptop workspace, blackout drapes, iron/ironing board

Quality Inn Charleston - Sikeston

2.5 star property
6.8 out of 10, (398)
"I consistently choose to stay there due to positive past encounters."
The price is ￥9,841
￥10,921 total
includes taxes & fees
Sep 7 - Sep 8
Quality Inn Charleston - Sikeston
Peaceful secluded cabin located near Horseshoe Lake
Exterior

Peaceful secluded cabin located near Horseshoe Lake

9.8 out of 10, Exceptional, (17)
"This stay was comfortable and quiet an amazing weekend stay!!"
The price is ￥16,620
￥27,322 total
includes taxes & fees
Aug 28 - Aug 29
Peaceful secluded cabin located near Horseshoe Lake
The Rested Duck Mallard Room
Interior

The Rested Duck Mallard Room

9.2 out of 10, Wonderful, (24)
"Great location and we are looking forward to a return trip. "
The price is ￥15,290
￥19,336 total
includes taxes & fees
Sep 8 - Sep 9
The Rested Duck Mallard Room
Charming 3-bedroom house near ball park in quiet neighborhood
Fridge, microwave, oven, stovetop

Charming 3-bedroom house near ball park in quiet neighborhood

10.0 out of 10, Exceptional, (9)
"Quaint stay to see Grand and kids. "
The price is ￥13,271
￥23,679 total
includes taxes & fees
Sep 16 - Sep 17
Charming 3-bedroom house near ball park in quiet neighborhood
Charming Home just minutes from Interstate and Mall
Exterior detail

Charming Home just minutes from Interstate and Mall

10.0 out of 10, Exceptional, (20)
"We enjoyed staying here very much. Clean and close to where we wanted to be!"
The price is ￥16,220
￥27,594 total
includes taxes & fees
Sep 18 - Sep 19
Charming Home just minutes from Interstate and Mall
Charming cottage overlooking Lake Acre
Exterior

Charming cottage overlooking Lake Acre

10.0 out of 10, Exceptional, (98)
"So Clean, Comfy and Serene!! Worth the drive for solitude."
The price is ￥19,906
￥41,410 total
includes taxes & fees
Aug 28 - Aug 29
Charming cottage overlooking Lake Acre
Eagle Inn Charleston
Desk, iron/ironing board, free WiFi, alarm clocks

Eagle Inn Charleston

2.0 star property
6.8 out of 10, (100)
"Comfortable bed, easy access to room"
The price is ￥9,424
￥10,460 total
includes taxes & fees
Sep 7 - Sep 8
Eagle Inn Charleston
Beautiful Cabin Retreat
Interior

Beautiful Cabin Retreat

8.2 out of 10, Very Good, (41)
"This is a very nice, peaceful cabin. The host was very friendly and accommodating. I would definitely stay here again."
The price is ￥17,694
￥30,317 total
includes taxes & fees
Aug 28 - Aug 29
Beautiful Cabin Retreat
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Cairo Hotel Reviews

Find out more about Cairo

Find out more about Cairo

Cairo B&B information

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Frequently asked questions

Searching for B&Bs in Cairo?
If you're looking for something a little different than your standard hotel experience, a stay at a bed and breakfast could be a great option for your getaway. When you want to explore some attractions in town, Mississippi River and Fort Defiance State Park are worth a stop.
How do you know if a B&B is the best choice for your stay?
With attentive service, opportunities to meet other guests, and of course a full breakfast to start the day, B&Bs provide a truly one-of-a-kind setting.
When should I book my B&B in Cairo?
When you're planning your stay in Cairo, be sure to take into account the year-round temperatures. The hottest months are usually July and August with an average temp of 76°F, while the coldest months are January and February with an average of 41°F. Average annual precipitation for Cairo is 61 inches.
What is there to do in Cairo?
When you want to check out some attractions in town, you might consider a visit to Mississippi River and Fort Defiance State Park. Mound City National Cemetery and Columbus-Belmont State Park are also some sites to visit if you want to see more of the area.
How can I get to and around Cairo?
You can map out your trip in and around Cairo ahead of time with these transportation options. Fly into Cairo, IL (CIR-Cairo Regional), which is located 4.7 mi (7.5 km) from the heart of the city. Otherwise, look for flights into Paducah, KY (PAH-Barkley Regional), which is 22.9 mi (36.8 km) away. If you'd like to explore around the area, consider renting a car to take in more sights.