Find All South Carolina Midlands Hotels
Change your mind
Book hotels with free cancellation
Be picky
Search almost a million properties worldwide
Find All South Carolina Midlands Hotels
We have found 2949 South Carolina Midlands Hotels
- Tru By Hilton Columbia Downtown
- Wyndham Garden Columbia/Ft. Jackson
- Howard Johnson by Wyndham Florence
- Park Inn by Radisson Florence, SC
- Graduate by Hilton Columbia SC
- Quality Inn Columbia Airport
- Motel 6 Fort Mill, SC - Charlotte
- The Ballantyne, A Luxury Collection Hotel, Charlotte
- Sleep Inn Columbia
- Country Inn & Suites by Radisson, Columbia, SC
- Woodspring Suites Columbia - Irmo
- Hyatt Place Florence Downtown
- Sleep Inn Fort Mill near Carowinds Blvd
- Holiday Inn Express & Suites Columbia-Fort Jackson by IHG
- Gallus Stadium Park Inn, Ascend Hotel Collection
- Days Inn by Wyndham Dillon
- Days Inn by Wyndham Florence/I-95 North
- Quality Inn & Suites Florence Civic Center
- Marriott Columbia
- Moxy Columbia Downtown
- Woodspring Suites Sumter Near Shaw Afb
- Doubletree by Hilton Columbia, SC
- Spark by Hilton Florence North I-95
- Sheraton Columbia Downtown Hotel
- Cambria Hotel Fort Mill
- Lexington Inn and Suites
- Spark by Hilton Orangeburg
- Red Roof Inn Dillon, SC
- Hotel Trundle
- Baymont by Wyndham Greenwood
- Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG
- Quality Inn Mullins - Marion
- Holiday Inn & Suites Columbia NE - Ft Jackson Area by IHG
Let Expedia take you to the best Hotels in South Carolina Midlands. You'll find the largest selection of hotel deals, discount prices, and cheap hotel rates on reservations anywhere in the world. Expedia, the leader in world travel, gives you customer reviews, maps, and the best selection of hotels near landmarks and attractions.