Find 4 Star Hotels in Northeast Missouri, MO from ¥16,177

Start date: Check-in selected.
To Date
End date: Check-out
  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check availability on Northeast Missouri 4 Star Hotels

Our top choices for Northeast Missouri 4-star hotels

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
4.0 star property
Downtown St. Louis
8.8 out of 10, Excellent, (1152)
"Really nice hotel!"
United States
DARIN
The price is ¥13,603
¥16,177 total
includes taxes & fees
Dec 18 - Dec 19
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Hilton St. Louis Frontenac

Hilton St. Louis Frontenac
4.0 star property
Frontenac
8.8 out of 10, Excellent, (1001)
"Clean room, felt like a mini apartment! The surrounding was beautiful. "
United States
Jane
The price is ¥20,315
¥23,665 total
includes taxes & fees
Dec 21 - Dec 22
Hilton St. Louis Frontenac

21C Museum Hotel St Louis

21C Museum Hotel St Louis
4.5 star property
Downtown West
9.0 out of 10, Wonderful, (1500)
"Room was perfect and parking was a breeze. We really enjoyed the art was wonderful. "
United States
London
The price is ¥20,894
¥25,210 total
includes taxes & fees
Dec 21 - Dec 22
21C Museum Hotel St Louis

The Cheshire

The Cheshire
4.0 star property
Richmond Heights
8.6 out of 10, Excellent, (1006)
"Excellent place to stay. "
United States
Todd
The price is ¥17,918
¥21,274 total
includes taxes & fees
Dec 29 - Dec 30
The Cheshire

Renaissance St. Louis Airport Hotel

Renaissance St. Louis Airport Hotel
4.0 star property
Berkeley
8.4 out of 10, Very Good, (1056)
"Staff was courteous and the room was clean."
United States
Mia
The price is ¥18,386
¥21,510 total
includes taxes & fees
Jan 2 - Jan 3, 2026
Renaissance St. Louis Airport Hotel

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
4.0 star property
Grand Center
8.8 out of 10, Excellent, (1036)
"Fun staff and a very cool hotel. Great room, too!"
United States
Christopher
The price is ¥18,573
¥21,903 total
includes taxes & fees
Dec 21 - Dec 22
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

Live by Loews - St.Louis

Live by Loews - St.Louis
4.0 star property
Downtown St. Louis
9.4 out of 10, Exceptional, (1104)
"Great staff"
United States
Phillip
The price is ¥23,216
¥27,610 total
includes taxes & fees
Dec 18 - Dec 19
Live by Loews - St.Louis

The Westin St. Louis

The Westin St. Louis
4.5 star property
Downtown St. Louis
8.6 out of 10, Excellent, (1006)
"Great location "
United States
Gregory
The price is ¥19,733
¥23,074 total
includes taxes & fees
Dec 21 - Dec 22
The Westin St. Louis

Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa
4.5 star property
St. Charles
8.4 out of 10, Very Good, (1005)
"Clean room, wonderful helpful pleasant staff, amenities, everything was great love staying here!"
United States
Robyn
The price is ¥23,706
¥30,289 total
includes taxes & fees
Dec 21 - Dec 22
Ameristar Casino Resort and Spa

DoubleTree by Hilton St. Louis Forest Park

DoubleTree by Hilton St. Louis Forest Park
4.0 star property
Central West End
8.2 out of 10, Very Good, (1001)
"Great room "
United States
Jessica
The price is ¥16,482
¥19,437 total
includes taxes & fees
Jan 15 - Jan 16, 2026
DoubleTree by Hilton St. Louis Forest Park

River City Casino & Hotel

River City Casino & Hotel
4.0 star property
St. Louis
9.0 out of 10, Wonderful, (1448)
"Awesome place to stay!!"
United States
Kaitlyn
The price is ¥12,750
¥17,099 total
includes taxes & fees
Jan 15 - Jan 16, 2026
River City Casino & Hotel

St. Louis Union Station Hotel, Curio Collection by Hilton

St. Louis Union Station Hotel, Curio Collection by Hilton
4.0 star property
Downtown West
8.4 out of 10, Very Good, (1007)
"Nice historic hotel"
United States
Michelle
The price is ¥22,103
¥26,288 total
includes taxes & fees
Dec 21 - Dec 22
St. Louis Union Station Hotel, Curio Collection by Hilton

Marriott St. Louis Grand

Marriott St. Louis Grand
4.0 star property
Downtown St. Louis
8.2 out of 10, Very Good, (1012)
"Rooms kind of small, but its an older hotel, but kinda iconic. "
United States
Lawrence
The price is ¥19,788
¥23,534 total
includes taxes & fees
Dec 21 - Dec 22
Marriott St. Louis Grand

Moonrise Hotel

Moonrise Hotel
4.0 star property
Delmar Loop
9.0 out of 10, Wonderful, (1916)
"Great service, unique hotel. Would absolutely stay again!"
United States
Michael
The price is ¥17,553
¥20,875 total
includes taxes & fees
Dec 17 - Dec 18
Moonrise Hotel

Marriott St. Louis Airport

Marriott St. Louis Airport
4.0 star property
Edmundson
8.0 out of 10, Very Good, (1004)
"Love that there is a restaurant inside the property so that after you check in you do not have to go elsewhere to find a place to eat. "
United States
Susan
The price is ¥19,881
¥23,725 total
includes taxes & fees
Dec 26 - Dec 27
Marriott St. Louis Airport

Hilton Pennywell St. Louis at the Arch

Hilton Pennywell St. Louis at the Arch
4.0 star property
Downtown St. Louis
8.8 out of 10, Excellent, (1016)
"My second time staying there as always it was lovely "
United States
Nina
The price is ¥16,080
¥18,963 total
includes taxes & fees
Dec 21 - Dec 22
Hilton Pennywell St. Louis at the Arch

Le Méridien St. Louis Clayton

Le Méridien St. Louis Clayton
4.0 star property
Clayton
8.8 out of 10, Excellent, (676)
"Small rooms but beautiful lobby. "
United States
Debbie
The price is ¥18,573
¥21,867 total
includes taxes & fees
Dec 19 - Dec 20
Le Méridien St. Louis Clayton

DoubleTree by Hilton St. Louis - Westport

DoubleTree by Hilton St. Louis - Westport
4.0 star property
Maryland Heights
8.2 out of 10, Very Good, (1007)
"Stayed one night felt very safe here"
United States
William
The price is ¥17,120
¥19,857 total
includes taxes & fees
Dec 28 - Dec 29
DoubleTree by Hilton St. Louis - Westport

Embassy Suites by Hilton St. Louis Downtown

Embassy Suites by Hilton St. Louis Downtown
4.0 star property
Downtown St. Louis
8.8 out of 10, Excellent, (1243)
"Great hospitality"
United States
Alejandro
The price is ¥16,703
¥19,864 total
includes taxes & fees
Dec 21 - Dec 22
Embassy Suites by Hilton St. Louis Downtown

The Royal Sonesta Chase Park Plaza St. Louis

The Royal Sonesta Chase Park Plaza St. Louis
4.5 star property
Central West End
9.0 out of 10, Wonderful, (1002)
"Always, a great time and place to stay."
United States
Lubna
The price is ¥24,774
¥33,809 total
includes taxes & fees
Dec 23 - Dec 24
The Royal Sonesta Chase Park Plaza St. Louis
Save an average of 15% on thousands of hotels when you're signed in

Explore similar 5-star hotels

Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Northeast Missouri.
The Ritz-Carlton, St. Louis

The Ritz-Carlton, St. Louis

100 Carondelet Plaza St. Louis MO
The price is ¥77,749 per night from Dec 21 to Dec 22
¥77,749
¥90,762 total
Dec 21 - Dec 22
includes taxes & fees
9.2/10 Wonderful! (553 reviews)
Still don't see what you're looking for?
See all properties in Northeast Missouri.
You can also use these popular filters to refine your search.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Northeast Missouri

Discover the family-friendly area of Northeast Missouri—live music, casinos, and top sights like St. Louis Union Station.

Grant\'s Farm which includes heritage architecture

Top Northeast Missouri Hotel Reviews

Frequently asked questions

What are the best 4-star hotels in Northeast Missouri?
You can find a variety of 4-star hotels in Northeast Missouri, including in St. Louis. St. Louis Union Station Hotel, Curio Collection by Hilton is an Expedia customer favorite here that offers premium bedding and concierge services. Another place that rates highly with travelers is The Last Hotel. Concierge services and a pillowtop mattress help make it their preferred choice.
How much does it cost to stay in a 4-star hotel in Northeast Missouri?
We can help you quickly locate the ideal 4-star hotel for your trip to Northeast Missouri. Use our filter tool to fine-tune your search by things like amenities, budget and star rating and get access to unbeatable deals in a couple of clicks.

  • Search for the lowest price from ¥90,762

What's the difference between 5-star and 4-star hotels in Northeast Missouri?
Give yourself the luxury treatment during your Northeast Missouri escape by checking in to a 4-star hotel. As well as featuring upscale accommodations, these properties are typically filled with amenities like large beds, complimentary bathrobes and more. A 5-star hotel will go the extra mile to make your trip an even more indulgent and unforgettable one. 24-hour front desk, luxurious spas and world-class dining are only the start of the exclusive services and conveniences you'll likely be able to enjoy.

Explore a world of travel with Expedia