San Luis Obispo Wine Country Luxury Vacations
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Top Luxury San Luis Obispo Wine Country Hotels
Madonna Inn
100 Madonna Road, San Luis Obispo, CA
Madonna Inn delivers luxe lodging where you'll enjoy pillowtop beds and more. Notable amenities include a spa, 2 outdoor tennis courts, and an outdoor pool.
9.2/10 Wonderful! (1,247 reviews)
"Loved it"
Reviewed on Sep 25, 2025
Avenue Inn Downtown San Luis Obispo
345 Marsh St, San Luis Obispo, CA
Be treated to luxurious accommodations at Avenue Inn Downtown San Luis Obispo, where you can enjoy amenities like premium channels, flat-screen TVs, and ...
9/10 Wonderful! (1,089 reviews)
"We always try and stay at the Avenue Inn when we travel to SLO. It’s always consistently clean, friendly staff, convenient to downtown, and a safe area!"
Reviewed on Sep 25, 2025
Avila La Fonda Hotel
101 San Miguel St, Avila Beach, CA
Enjoy a posh stay at Avila La Fonda Hotel, where you'll find private hot tubs and pillowtop beds.
9.4/10 Exceptional! (1,002 reviews)
"Great staff and service"
Reviewed on Sep 17, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
